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The map label for this gene is mocR [H]

Identifier: 213159021

GI number: 213159021

Start: 3840347

End: 3841846

Strand: Direct

Name: mocR [H]

Synonym: AB57_3729

Alternate gene names: 213159021

Gene position: 3840347-3841846 (Clockwise)

Preceding gene: 213159018

Following gene: 213159024

Centisome position: 94.81

GC content: 45.8

Gene sequence:

>1500_bases
TTGCGTAGTTTACTTGGAGATCATTTGCTGCAACGACTCCAACAGGACACTGAAGGGAAACTACATCAACGCCTTTTCCG
TTGCCTGCGTGGTGCCATTATTGATGGAGTGATCCAGCCTAAGACTCGTCTACCTGCATCACGCGATTTAGCCAGTGAAA
TTCATGTTTCGAGAAATACCGTTCTTAGTGCCTACGAACAACTACAGGCCGAAGGCTATTTAGAAGCACGGACAGGACAT
GGCACATGGGTTGCCGAAAAGTTACCAGAGAGTTTTTTAAATACACAAAACAAGAAAAAAGTAGTTTCTAGCCCAAATAT
TCAAAGTTCTTACGCCCTCTCACAGCGTGGCTCAAACTTATTGGGCTATGCCGCAGCCTCGCCACATCAATGGGGAGCCT
TTGTTCCGGGAGCACCCGATGTTACCGAGTTTCCACATCATATTTTTAGTCGTATTCAAGCACGCTTAAGCCGCGAACCG
GACATTAACCGTCTAATTTATAGCAATGCAGGTGGATGCATAGAGCTTCGAAGTGCATTGGCAGATTACTTACGTGTTGC
GCGTTCAGTCCAGTGCGATGCGGACCAGATTATTATTACCGAAGGCATTCATCAAGCCATTGATTTAGTCTCACGTGCAC
TGAGTGATATGGGAGATAAAGTCTGGATTGAAGATCCCGCTTATTGGGGAATGCGTAATACGTTACGGATTAATGGCCTC
GATATTCAGCCGATGCCTGTCGATGCTGAAGGCATTATTCCTGAAGAAAATCCGGCAGTACCGCCTAAACTCATTTTTGT
CACACCATCACATCAATATCCGCTTGGCTCACATTTAAGCCTTGATCGTCGCAGACAATTGATTCAGATTGCACGTCAGC
ACAATAGCTGGATTGTAGAAGATGACTATGACAGTGAGTTCCGTTTCTCGGGCCAGCCTTATCCATCTTTGCAAGGCTTA
GAAAATAACGCACCTGTTTTATATATGGGCACGTTTAGTAAAACTATTTATCCATCCTTAAGAATTGGCTATTTGGTCGT
CCCTAAGCCGTTATTTTCACCGCTACGTATTGTTGCGGCCGAGCTTTATCGTGGTGGGCACTTGCTTGAGCAAAAAGCCC
TCGCTGAATTTATTCGTGAAGGCCATTATGAAGCGCATATTCGCCGTATGCGCCTGCTCTATGGTAAACGCCGCGATTAC
TTGGTGAGCTTAATTCAACGCTATCTTGGCCCCGAATTTATTCATGAATATGATGAAGCAGCAGGGTTACATCTGGTTTT
AAAACTACCGAACTCTTGCGATGATGTCGCCATTGCAGCCACAGCACTTGAACGTGGCGTCAAGGTTCGTCCACTGTCTC
AGTACTACATGCAATCACATGCACATGCCGAACGTGGACTGCTGATGGGCTTTGCCTGTGTAAATGAAAAAGATATGGTG
ATGGCTTTTGGTGTCTTGCTCCAGTGCTTACGTGAAGCAGGTGTACCCACACTGAATTGA

Upstream 100 bases:

>100_bases
TTAATTTTCAGGGTGCTTTACAACGACTGCCTATGCATGTAATTTCGCTCGTCTGATGCCAACTGACGAGAGCCACTTTT
TAACTGTAGGAGAGAGCCAA

Downstream 100 bases:

>100_bases
TCTTTTTATCTGAGCAAAATAAAAAAGAGCCTCACTGTGAGGCTCTTTTGATTTAAAAATTTAAACTAACTTTTCTTCAT
GGCTATGAGTTAAATGGGTT

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MRSLLGDHLLQRLQQDTEGKLHQRLFRCLRGAIIDGVIQPKTRLPASRDLASEIHVSRNTVLSAYEQLQAEGYLEARTGH
GTWVAEKLPESFLNTQNKKKVVSSPNIQSSYALSQRGSNLLGYAAASPHQWGAFVPGAPDVTEFPHHIFSRIQARLSREP
DINRLIYSNAGGCIELRSALADYLRVARSVQCDADQIIITEGIHQAIDLVSRALSDMGDKVWIEDPAYWGMRNTLRINGL
DIQPMPVDAEGIIPEENPAVPPKLIFVTPSHQYPLGSHLSLDRRRQLIQIARQHNSWIVEDDYDSEFRFSGQPYPSLQGL
ENNAPVLYMGTFSKTIYPSLRIGYLVVPKPLFSPLRIVAAELYRGGHLLEQKALAEFIREGHYEAHIRRMRLLYGKRRDY
LVSLIQRYLGPEFIHEYDEAAGLHLVLKLPNSCDDVAIAATALERGVKVRPLSQYYMQSHAHAERGLLMGFACVNEKDMV
MAFGVLLQCLREAGVPTLN

Sequences:

>Translated_499_residues
MRSLLGDHLLQRLQQDTEGKLHQRLFRCLRGAIIDGVIQPKTRLPASRDLASEIHVSRNTVLSAYEQLQAEGYLEARTGH
GTWVAEKLPESFLNTQNKKKVVSSPNIQSSYALSQRGSNLLGYAAASPHQWGAFVPGAPDVTEFPHHIFSRIQARLSREP
DINRLIYSNAGGCIELRSALADYLRVARSVQCDADQIIITEGIHQAIDLVSRALSDMGDKVWIEDPAYWGMRNTLRINGL
DIQPMPVDAEGIIPEENPAVPPKLIFVTPSHQYPLGSHLSLDRRRQLIQIARQHNSWIVEDDYDSEFRFSGQPYPSLQGL
ENNAPVLYMGTFSKTIYPSLRIGYLVVPKPLFSPLRIVAAELYRGGHLLEQKALAEFIREGHYEAHIRRMRLLYGKRRDY
LVSLIQRYLGPEFIHEYDEAAGLHLVLKLPNSCDDVAIAATALERGVKVRPLSQYYMQSHAHAERGLLMGFACVNEKDMV
MAFGVLLQCLREAGVPTLN
>Mature_499_residues
MRSLLGDHLLQRLQQDTEGKLHQRLFRCLRGAIIDGVIQPKTRLPASRDLASEIHVSRNTVLSAYEQLQAEGYLEARTGH
GTWVAEKLPESFLNTQNKKKVVSSPNIQSSYALSQRGSNLLGYAAASPHQWGAFVPGAPDVTEFPHHIFSRIQARLSREP
DINRLIYSNAGGCIELRSALADYLRVARSVQCDADQIIITEGIHQAIDLVSRALSDMGDKVWIEDPAYWGMRNTLRINGL
DIQPMPVDAEGIIPEENPAVPPKLIFVTPSHQYPLGSHLSLDRRRQLIQIARQHNSWIVEDDYDSEFRFSGQPYPSLQGL
ENNAPVLYMGTFSKTIYPSLRIGYLVVPKPLFSPLRIVAAELYRGGHLLEQKALAEFIREGHYEAHIRRMRLLYGKRRDY
LVSLIQRYLGPEFIHEYDEAAGLHLVLKLPNSCDDVAIAATALERGVKVRPLSQYYMQSHAHAERGLLMGFACVNEKDMV
MAFGVLLQCLREAGVPTLN

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=318, Percent_Identity=27.3584905660377, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI33469970, Length=318, Percent_Identity=27.3584905660377, Blast_Score=112, Evalue=1e-24,
Organism=Escherichia coli, GI1787710, Length=445, Percent_Identity=27.4157303370787, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1790797, Length=434, Percent_Identity=28.3410138248848, Blast_Score=123, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321236, Length=282, Percent_Identity=22.6950354609929, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56174; Mature: 56174

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLLGDHLLQRLQQDTEGKLHQRLFRCLRGAIIDGVIQPKTRLPASRDLASEIHVSRNT
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHH
VLSAYEQLQAEGYLEARTGHGTWVAEKLPESFLNTQNKKKVVSSPNIQSSYALSQRGSNL
HHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHCCCCE
LGYAAASPHQWGAFVPGAPDVTEFPHHIFSRIQARLSREPDINRLIYSNAGGCIELRSAL
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHH
ADYLRVARSVQCDADQIIITEGIHQAIDLVSRALSDMGDKVWIEDPAYWGMRNTLRINGL
HHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCE
DIQPMPVDAEGIIPEENPAVPPKLIFVTPSHQYPLGSHLSLDRRRQLIQIARQHNSWIVE
ECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
DDYDSEFRFSGQPYPSLQGLENNAPVLYMGTFSKTIYPSLRIGYLVVPKPLFSPLRIVAA
CCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCHHHCCCCEECEEEECCHHHHHHHHHHH
ELYRGGHLLEQKALAEFIREGHYEAHIRRMRLLYGKRRDYLVSLIQRYLGPEFIHEYDEA
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHC
AGLHLVLKLPNSCDDVAIAATALERGVKVRPLSQYYMQSHAHAERGLLMGFACVNEKDMV
CCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHH
MAFGVLLQCLREAGVPTLN
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRSLLGDHLLQRLQQDTEGKLHQRLFRCLRGAIIDGVIQPKTRLPASRDLASEIHVSRNT
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHH
VLSAYEQLQAEGYLEARTGHGTWVAEKLPESFLNTQNKKKVVSSPNIQSSYALSQRGSNL
HHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHCCCCE
LGYAAASPHQWGAFVPGAPDVTEFPHHIFSRIQARLSREPDINRLIYSNAGGCIELRSAL
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHH
ADYLRVARSVQCDADQIIITEGIHQAIDLVSRALSDMGDKVWIEDPAYWGMRNTLRINGL
HHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCE
DIQPMPVDAEGIIPEENPAVPPKLIFVTPSHQYPLGSHLSLDRRRQLIQIARQHNSWIVE
ECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
DDYDSEFRFSGQPYPSLQGLENNAPVLYMGTFSKTIYPSLRIGYLVVPKPLFSPLRIVAA
CCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCHHHCCCCEECEEEECCHHHHHHHHHHH
ELYRGGHLLEQKALAEFIREGHYEAHIRRMRLLYGKRRDYLVSLIQRYLGPEFIHEYDEA
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHC
AGLHLVLKLPNSCDDVAIAATALERGVKVRPLSQYYMQSHAHAERGLLMGFACVNEKDMV
CCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHH
MAFGVLLQCLREAGVPTLN
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]