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The map label for this gene is cat1 [H]

Identifier: 213158977

GI number: 213158977

Start: 3799072

End: 3800586

Strand: Direct

Name: cat1 [H]

Synonym: AB57_3679

Alternate gene names: 213158977

Gene position: 3799072-3800586 (Clockwise)

Preceding gene: 213158976

Following gene: 213158978

Centisome position: 93.79

GC content: 41.19

Gene sequence:

>1515_bases
ATGTCTTTAAGTCGTATTCGCCTAGCTTCTCTTCATGACAAGGTCATCAGTGCTGAACAAGCTGCGCAATTCATCGAAAA
TGGAATGACCGTTGGTATGAGTGGTTTTACTCGTGCTGGCGAAGCTAAAGCTGTTCCACAAGCACTTGTAGAGCTTGCAA
AAAAGAATCCGTTAAAAATCACGTTAATTACGGGTGCTAGCTTAGGTAATGACTTAGACAAACAACTCACGGAAGCAGGT
GTTTTATCTCGTCGCATGCCATTCCAAGTGGATAACACTTTACGCCGCGCAATTAATAACGGCGAAGTCATGTTTATTGA
CCAACACTTGTCAGAAACTGTTGAGCAAATGCGTAACCAGCAACTTAAACGTCCAGATGTTGCGGTCATTGAAGCAATTG
CGATTACTGAAGATGGTGGCATTATTCCAACAACTTCTGTTGGTAACTCTGCAAGTTTTGCAATTTTTGCCGAAAAAGTA
ATTGTTGAAATCAACACTTCTTTAAGCGAAAGCTTTGAAGGTTTGCACGATATCTATATTCCAACTTATCGTCCAACACG
TACGCCAATTCCATTAACAAAAGTGGACGAACGTATTGGTACAACAGCTATCCAAATCGATCCTTCGAAAATTGTTGGTA
TTGTATTTAACGATACACATGACTCTCCATCGACAGTCACTCCTCCAGATGATGAGACTCAAGGCATTGCCAATCACCTT
ATCGCATTCTTTGAAAAAGAAGTGGCTGAAGGTCGTTTACCGAAAAACCTTGGTCCACTCCAAGCAGGGATCGGTTCAAT
TGCAAACGCTGTACTAACAGGTTTAAAAGATTCTAATTTTGAAGACCTCATCATGTACTCAGAAGTACTACAAGACTGTA
CTTTTGAATTAATTGATGCAGGCAAAATGAAATTTGCTTCTGGTAGTTCAATTACGCTTTCAGCAAAATGTGGTGAAAAA
GTTTTTGGTAATATCGAAGCTTACAAAGACAAATTAGTGCTTCGTCCACAAGAAATTTCTAATCACCCTGAGCTTGTACG
TCGTTTAGGTATTATCGGTATTAATACTGCACTTGAGTTTGATATTTACGGTAACGTGAACTCAACTCACGTGTGTGGTA
CTAAAATGATGAACGGTATTGGTGGTTCAGGTGACTTCGCTCGTAATGCGCACTTGGCAATCTTTGTAACCAAATCAATC
GCTAAAGGCGGCGATATTTCTTCTATCGTGCCAATGGTGAGTCACGTTGACCACAGTGAACACGACGTTGATATTTTAGT
GACAGAGCAAGGTTTAGCAGACTTACGTGGTTTAGCACCTCGTGAACGCGCTCGCGCTATTATCGACAACTGCGTACACC
CGCTTTACCGTGATGCATTAAATGACTATTTTGATCGTGCATGTGCTAAAGGCGGACATACACCTCACTTACTTCGTGAA
GCATTGTCTTGGCATGCAAACTTTGAAGAAACAGGCCAAATGCTTCAACCAACACCAGTTGCAAAATCAGCTTAA

Upstream 100 bases:

>100_bases
CGCATTTATTTAAAAAATTAGACCTTAGCCTAACACCTATGCACTTTTCATTTTTTCATAGCTAAAATCCGTTATGTTTT
GACAATATTGAGGATGTCCA

Downstream 100 bases:

>100_bases
GACATACTTTTAATTTAAGCACTCCTACGGGGGTGCTTTTTTATTTGTGTAAATTATTCACAAACTACTGCTCAAGTTCG
AATTTTTATTTTATCTTTTC

Product: succinyl-CoA:coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MSLSRIRLASLHDKVISAEQAAQFIENGMTVGMSGFTRAGEAKAVPQALVELAKKNPLKITLITGASLGNDLDKQLTEAG
VLSRRMPFQVDNTLRRAINNGEVMFIDQHLSETVEQMRNQQLKRPDVAVIEAIAITEDGGIIPTTSVGNSASFAIFAEKV
IVEINTSLSESFEGLHDIYIPTYRPTRTPIPLTKVDERIGTTAIQIDPSKIVGIVFNDTHDSPSTVTPPDDETQGIANHL
IAFFEKEVAEGRLPKNLGPLQAGIGSIANAVLTGLKDSNFEDLIMYSEVLQDCTFELIDAGKMKFASGSSITLSAKCGEK
VFGNIEAYKDKLVLRPQEISNHPELVRRLGIIGINTALEFDIYGNVNSTHVCGTKMMNGIGGSGDFARNAHLAIFVTKSI
AKGGDISSIVPMVSHVDHSEHDVDILVTEQGLADLRGLAPRERARAIIDNCVHPLYRDALNDYFDRACAKGGHTPHLLRE
ALSWHANFEETGQMLQPTPVAKSA

Sequences:

>Translated_504_residues
MSLSRIRLASLHDKVISAEQAAQFIENGMTVGMSGFTRAGEAKAVPQALVELAKKNPLKITLITGASLGNDLDKQLTEAG
VLSRRMPFQVDNTLRRAINNGEVMFIDQHLSETVEQMRNQQLKRPDVAVIEAIAITEDGGIIPTTSVGNSASFAIFAEKV
IVEINTSLSESFEGLHDIYIPTYRPTRTPIPLTKVDERIGTTAIQIDPSKIVGIVFNDTHDSPSTVTPPDDETQGIANHL
IAFFEKEVAEGRLPKNLGPLQAGIGSIANAVLTGLKDSNFEDLIMYSEVLQDCTFELIDAGKMKFASGSSITLSAKCGEK
VFGNIEAYKDKLVLRPQEISNHPELVRRLGIIGINTALEFDIYGNVNSTHVCGTKMMNGIGGSGDFARNAHLAIFVTKSI
AKGGDISSIVPMVSHVDHSEHDVDILVTEQGLADLRGLAPRERARAIIDNCVHPLYRDALNDYFDRACAKGGHTPHLLRE
ALSWHANFEETGQMLQPTPVAKSA
>Mature_503_residues
SLSRIRLASLHDKVISAEQAAQFIENGMTVGMSGFTRAGEAKAVPQALVELAKKNPLKITLITGASLGNDLDKQLTEAGV
LSRRMPFQVDNTLRRAINNGEVMFIDQHLSETVEQMRNQQLKRPDVAVIEAIAITEDGGIIPTTSVGNSASFAIFAEKVI
VEINTSLSESFEGLHDIYIPTYRPTRTPIPLTKVDERIGTTAIQIDPSKIVGIVFNDTHDSPSTVTPPDDETQGIANHLI
AFFEKEVAEGRLPKNLGPLQAGIGSIANAVLTGLKDSNFEDLIMYSEVLQDCTFELIDAGKMKFASGSSITLSAKCGEKV
FGNIEAYKDKLVLRPQEISNHPELVRRLGIIGINTALEFDIYGNVNSTHVCGTKMMNGIGGSGDFARNAHLAIFVTKSIA
KGGDISSIVPMVSHVDHSEHDVDILVTEQGLADLRGLAPRERARAIIDNCVHPLYRDALNDYFDRACAKGGHTPHLLREA
LSWHANFEETGQMLQPTPVAKSA

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=45.679012345679, Blast_Score=434, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI32563853, Length=258, Percent_Identity=31.3953488372093, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17538151, Length=243, Percent_Identity=32.0987654320988, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319456, Length=513, Percent_Identity=45.6140350877193, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 54715; Mature: 54584

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSRIRLASLHDKVISAEQAAQFIENGMTVGMSGFTRAGEAKAVPQALVELAKKNPLKI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCEEE
TLITGASLGNDLDKQLTEAGVLSRRMPFQVDNTLRRAINNGEVMFIDQHLSETVEQMRNQ
EEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHH
QLKRPDVAVIEAIAITEDGGIIPTTSVGNSASFAIFAEKVIVEINTSLSESFEGLHDIYI
HCCCCCHHHEEEEEEECCCCEECCCCCCCCCEEEEEEEEEEEEECCHHHHHHCCHHHEEC
PTYRPTRTPIPLTKVDERIGTTAIQIDPSKIVGIVFNDTHDSPSTVTPPDDETQGIANHL
CCCCCCCCCCCHHHHHHHHCCEEEEECHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
IAFFEKEVAEGRLPKNLGPLQAGIGSIANAVLTGLKDSNFEDLIMYSEVLQDCTFELIDA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
GKMKFASGSSITLSAKCGEKVFGNIEAYKDKLVLRPQEISNHPELVRRLGIIGINTALEF
CCEEECCCCCEEEECCCCHHHHCCHHHHHHHHEECHHHHCCCHHHHHHHCCEEECCEEEE
DIYGNVNSTHVCGTKMMNGIGGSGDFARNAHLAIFVTKSIAKGGDISSIVPMVSHVDHSE
EEECCCCCCEECHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCC
HDVDILVTEQGLADLRGLAPRERARAIIDNCVHPLYRDALNDYFDRACAKGGHTPHLLRE
CCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHANFEETGQMLQPTPVAKSA
HHHHCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SLSRIRLASLHDKVISAEQAAQFIENGMTVGMSGFTRAGEAKAVPQALVELAKKNPLKI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCEEE
TLITGASLGNDLDKQLTEAGVLSRRMPFQVDNTLRRAINNGEVMFIDQHLSETVEQMRNQ
EEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHH
QLKRPDVAVIEAIAITEDGGIIPTTSVGNSASFAIFAEKVIVEINTSLSESFEGLHDIYI
HCCCCCHHHEEEEEEECCCCEECCCCCCCCCEEEEEEEEEEEEECCHHHHHHCCHHHEEC
PTYRPTRTPIPLTKVDERIGTTAIQIDPSKIVGIVFNDTHDSPSTVTPPDDETQGIANHL
CCCCCCCCCCCHHHHHHHHCCEEEEECHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
IAFFEKEVAEGRLPKNLGPLQAGIGSIANAVLTGLKDSNFEDLIMYSEVLQDCTFELIDA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
GKMKFASGSSITLSAKCGEKVFGNIEAYKDKLVLRPQEISNHPELVRRLGIIGINTALEF
CCEEECCCCCEEEECCCCHHHHCCHHHHHHHHEECHHHHCCCHHHHHHHCCEEECCEEEE
DIYGNVNSTHVCGTKMMNGIGGSGDFARNAHLAIFVTKSIAKGGDISSIVPMVSHVDHSE
EEECCCCCCEECHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCC
HDVDILVTEQGLADLRGLAPRERARAIIDNCVHPLYRDALNDYFDRACAKGGHTPHLLRE
CCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHANFEETGQMLQPTPVAKSA
HHHHCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]