| Definition | Acinetobacter baumannii AB0057, complete genome. |
|---|---|
| Accession | NC_011586 |
| Length | 4,050,513 |
Click here to switch to the map view.
The map label for this gene is mrcA [H]
Identifier: 213158948
GI number: 213158948
Start: 3758489
End: 3760954
Strand: Direct
Name: mrcA [H]
Synonym: AB57_3649
Alternate gene names: 213158948
Gene position: 3758489-3760954 (Clockwise)
Preceding gene: 213158931
Following gene: 213158958
Centisome position: 92.79
GC content: 42.05
Gene sequence:
>2466_bases ATGTATCTCTATATTGCCCCAGCGCTTCCGGAAATGAGTTCACTAAAAAAAGCACCGCTTTTAAAACCATTGCAAGTCTA TACAGCCGACAATCAACTTATTGCTGAATACGGTGGTAAACTTTCTATTCCGGTTGAATACAAACAAATTCCTCCTAATT TTATTCATGCATTCCTAGCAGCAGAAGATTCTTCTTTCTTTGAACATAGCGGCATTAGTTTTAAAGGTTTAGGCCGTGCT TTGAGTGAAAGTGTTACGGGTTCTGATGTACAAACTGGTGGCTCAACCATCACGATGCAGGTCGCAAAGAACTATTATTT AAGTCCAGAAAGAACATTAAAACGCAAACTAACAGAAATCTTTTTGGCTCGAAAAATTGAGCAAAACTTATCCAAAGAAG ACATCTTAAGCCTCTATGTAAATAAGATTTTCTTAGGTAAAAATGCTTACGGTATCGCAGCGGCAGCAAAGATTTACTAC AACAAAAGCATTAATGAGCTCAGCATTGCCCAAATGGCCATGATTGCCGGCTTGCCTAAAGCACCATCTAAATATAATCC AGTTGTTAACCCTGAGCGTGCACTTGAACGTCGCAACTGGATTTTAGGCCGAATGCTTCAACTTGGTTATATCTCTCAAA CGGAATATCAAAAGGCCGTTGCAGAGCCAATCAATTTGAATATGCCCAACCGTGACCTAAATAATATTCATCCTTACGCA GGTGAAATGGTCCGCTCAGAGCTTGTAAAACATTTTGGTGAACAAGCAATTGATTCTGGTTATAAAGTCTACACAACAAT TAATGCGAAACGCCAAGCGATTGCGGAAAAAGCTGTGCAGGACGGTCTTGAAGCTTATGACCGTCGTCATGGCTGGCGTG GTGCAGAAGCACATGATAAGCCATTAAGCGAATTTAGAGCATATGCCAACACTTATCCGGCGCAAGTCACCAAGGTAAAT AGCAGCTCTTTTGAAGCATTAATGCAAGATGGCTCAACAGTAACCGTGCAATGGTCCGGCATGTCATGGGCCCGTCCCTA TCGCAATGCAAATAGCGTAGGTGCAGCGCCTTCTCGTGCATCTCAAATTGTTAAAGTTAAAGATATTGTTCGTTTACGCC CAAATGAAGCTAAAACTGCGTGGTCACTAGTTCAAGTACCAAAAGTACAAGGTCAGCTCATTGCAATTAACCCAAACGAT GGGTCAATTGAAGCAATTGTAGGTGGTTATAATTTCTATCAATCAAAATTTAACCGTGCTTTACAAGGCTGGCGTCAACC AGGTTCTACCATCAAACCATTCCTCTATGCTTTAGCATTAGAACGTGGCATGACACCTTATAGTATGGTGAATGATAGCC CTATTACGATTGGCAAGTGGACACCGAAGAACTCTGATGGTCGCTACCTAGGCATGATCCCGTTACGCCGTGCTTTGTAT TTGTCTCGTAATACGGTTTCAGTAAGACTCTTACAAACTGTAGGAATTGAACGTACTCGCCAATTATTCATGGATTTTGG TTTACAAGAGGATCAAATTCCACGTAACTACACCATTGCTTTAGGTACGCCTCAAGTATTACCAATTCAAATGGCAACTG GTTATGCAACATTTGCAAACGGTGGTTACCGCGTTCAACCGCATTTTATTCAGCGTATTGAAGATGCATACGGTAAAGTC ATTTACGAAGCCAAGCCAGAATATGCATGTATTCCATGTATTAATGCTCCTGAGACAACTGACGATGCACAGGTAACTAC TCCAGATGATCAAGTTGTTGAAGTCACAAATAAAGAGCTAGAGCAGAAAGAAAAGACAACCAAACAACTCAATCTTAAAC AGACGGACAAAAATAACAGTCAATATCGTCAAGCTCAGCGCATTTTAAAATCAAGCTCTGCTTATGACATGGCAAATATC TTACGTGACGTAATTGAGCATGGTACAGGTCGTGCTGCACTCAAGATCGGCCGTAGTGATTTAGGAGGTAAAACAGGTAC GACTAACGATGCAAAAGATGCATGGTTTGCAGGTTTTAATGGCAAGTTAGTAACTGTAACATGGGTTGGTTTTGACCAGC CGACTACACTTGGTCGCCGTGAGTATGGTGGTATTGCTGCACTACCAATCTGGATTAACTTTATGGGTCAAGCATTGCAA GGTACACCAGCTGCTTGGGTTCGTTTAGAAAAAGATGCTCAGGCACCTATTTCTCGCGATAAGCAAGAAGTCACAGCTGA AGTAGGCGATAAGAAAACCTATCGTGCTGCCCCTCCATTAGCACGCCCACTCTATCGTCCTGCACCACCACAACCTAAAA CCACCAATAATGACTTCGATGACTTACCGGGTGAGGAAATTGTGATTCCTTCCAAGACAACCCCTCCAGCAATGAAACCT TCGCAAGGGGCAGCGCCGAAGCGTGAAAAAGATGAATTAGAAAACTTGATTAATCAAATTGAATAA
Upstream 100 bases:
>100_bases CTTACTTATCATGAAAAAGCTATCCAGTTTGGGCTTCGTGCGTCCAATTTTTTTGATCATTATTATTATCTTAGTCTCAC TTCCGATGGGATTCTATGGC
Downstream 100 bases:
>100_bases AAATAAAAAAGCCATCGTTAGATGGCTTTTTTATTACGCTTTTGAAAAAGATAAATTTGAAAAGATGCGGTCACTTGTAA GTGTGCTTTCTGTTCTAATT
Product: penicillin-binding protein 1A
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 821; Mature: 821
Protein sequence:
>821_residues MYLYIAPALPEMSSLKKAPLLKPLQVYTADNQLIAEYGGKLSIPVEYKQIPPNFIHAFLAAEDSSFFEHSGISFKGLGRA LSESVTGSDVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKIEQNLSKEDILSLYVNKIFLGKNAYGIAAAAKIYY NKSINELSIAQMAMIAGLPKAPSKYNPVVNPERALERRNWILGRMLQLGYISQTEYQKAVAEPINLNMPNRDLNNIHPYA GEMVRSELVKHFGEQAIDSGYKVYTTINAKRQAIAEKAVQDGLEAYDRRHGWRGAEAHDKPLSEFRAYANTYPAQVTKVN SSSFEALMQDGSTVTVQWSGMSWARPYRNANSVGAAPSRASQIVKVKDIVRLRPNEAKTAWSLVQVPKVQGQLIAINPND GSIEAIVGGYNFYQSKFNRALQGWRQPGSTIKPFLYALALERGMTPYSMVNDSPITIGKWTPKNSDGRYLGMIPLRRALY LSRNTVSVRLLQTVGIERTRQLFMDFGLQEDQIPRNYTIALGTPQVLPIQMATGYATFANGGYRVQPHFIQRIEDAYGKV IYEAKPEYACIPCINAPETTDDAQVTTPDDQVVEVTNKELEQKEKTTKQLNLKQTDKNNSQYRQAQRILKSSSAYDMANI LRDVIEHGTGRAALKIGRSDLGGKTGTTNDAKDAWFAGFNGKLVTVTWVGFDQPTTLGRREYGGIAALPIWINFMGQALQ GTPAAWVRLEKDAQAPISRDKQEVTAEVGDKKTYRAAPPLARPLYRPAPPQPKTTNNDFDDLPGEEIVIPSKTTPPAMKP SQGAAPKREKDELENLINQIE
Sequences:
>Translated_821_residues MYLYIAPALPEMSSLKKAPLLKPLQVYTADNQLIAEYGGKLSIPVEYKQIPPNFIHAFLAAEDSSFFEHSGISFKGLGRA LSESVTGSDVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKIEQNLSKEDILSLYVNKIFLGKNAYGIAAAAKIYY NKSINELSIAQMAMIAGLPKAPSKYNPVVNPERALERRNWILGRMLQLGYISQTEYQKAVAEPINLNMPNRDLNNIHPYA GEMVRSELVKHFGEQAIDSGYKVYTTINAKRQAIAEKAVQDGLEAYDRRHGWRGAEAHDKPLSEFRAYANTYPAQVTKVN SSSFEALMQDGSTVTVQWSGMSWARPYRNANSVGAAPSRASQIVKVKDIVRLRPNEAKTAWSLVQVPKVQGQLIAINPND GSIEAIVGGYNFYQSKFNRALQGWRQPGSTIKPFLYALALERGMTPYSMVNDSPITIGKWTPKNSDGRYLGMIPLRRALY LSRNTVSVRLLQTVGIERTRQLFMDFGLQEDQIPRNYTIALGTPQVLPIQMATGYATFANGGYRVQPHFIQRIEDAYGKV IYEAKPEYACIPCINAPETTDDAQVTTPDDQVVEVTNKELEQKEKTTKQLNLKQTDKNNSQYRQAQRILKSSSAYDMANI LRDVIEHGTGRAALKIGRSDLGGKTGTTNDAKDAWFAGFNGKLVTVTWVGFDQPTTLGRREYGGIAALPIWINFMGQALQ GTPAAWVRLEKDAQAPISRDKQEVTAEVGDKKTYRAAPPLARPLYRPAPPQPKTTNNDFDDLPGEEIVIPSKTTPPAMKP SQGAAPKREKDELENLINQIE >Mature_821_residues MYLYIAPALPEMSSLKKAPLLKPLQVYTADNQLIAEYGGKLSIPVEYKQIPPNFIHAFLAAEDSSFFEHSGISFKGLGRA LSESVTGSDVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKIEQNLSKEDILSLYVNKIFLGKNAYGIAAAAKIYY NKSINELSIAQMAMIAGLPKAPSKYNPVVNPERALERRNWILGRMLQLGYISQTEYQKAVAEPINLNMPNRDLNNIHPYA GEMVRSELVKHFGEQAIDSGYKVYTTINAKRQAIAEKAVQDGLEAYDRRHGWRGAEAHDKPLSEFRAYANTYPAQVTKVN SSSFEALMQDGSTVTVQWSGMSWARPYRNANSVGAAPSRASQIVKVKDIVRLRPNEAKTAWSLVQVPKVQGQLIAINPND GSIEAIVGGYNFYQSKFNRALQGWRQPGSTIKPFLYALALERGMTPYSMVNDSPITIGKWTPKNSDGRYLGMIPLRRALY LSRNTVSVRLLQTVGIERTRQLFMDFGLQEDQIPRNYTIALGTPQVLPIQMATGYATFANGGYRVQPHFIQRIEDAYGKV IYEAKPEYACIPCINAPETTDDAQVTTPDDQVVEVTNKELEQKEKTTKQLNLKQTDKNNSQYRQAQRILKSSSAYDMANI LRDVIEHGTGRAALKIGRSDLGGKTGTTNDAKDAWFAGFNGKLVTVTWVGFDQPTTLGRREYGGIAALPIWINFMGQALQ GTPAAWVRLEKDAQAPISRDKQEVTAEVGDKKTYRAAPPLARPLYRPAPPQPKTTNNDFDDLPGEEIVIPSKTTPPAMKP SQGAAPKREKDELENLINQIE
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=769, Percent_Identity=40.8322496749025, Blast_Score=565, Evalue=1e-162, Organism=Escherichia coli, GI1786343, Length=263, Percent_Identity=34.6007604562738, Blast_Score=145, Evalue=1e-35, Organism=Escherichia coli, GI1788867, Length=249, Percent_Identity=33.7349397590361, Blast_Score=124, Evalue=3e-29, Organism=Escherichia coli, GI1789601, Length=165, Percent_Identity=33.9393939393939, Blast_Score=89, Evalue=9e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 91390; Mature: 91390
Theoretical pI: Translated: 9.71; Mature: 9.71
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYLYIAPALPEMSSLKKAPLLKPLQVYTADNQLIAEYGGKLSIPVEYKQIPPNFIHAFLA CEEEEECCCCCHHHHHCCCCCCCEEEEECCCEEHHHCCCEEEEEEEHHHCCHHHHHHHHH AEDSSFFEHSGISFKGLGRALSESVTGSDVQTGGSTITMQVAKNYYLSPERTLKRKLTEI CCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH FLARKIEQNLSKEDILSLYVNKIFLGKNAYGIAAAAKIYYNKSINELSIAQMAMIAGLPK HHHHHHHHCCCHHHHHHHHHHHHEECCCCCCHHHHHHEEECCCCCHHHHHHHHHHHCCCC APSKYNPVVNPERALERRNWILGRMLQLGYISQTEYQKAVAEPINLNMPNRDLNNIHPYA CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHH GEMVRSELVKHFGEQAIDSGYKVYTTINAKRQAIAEKAVQDGLEAYDRRHGWRGAEAHDK HHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC PLSEFRAYANTYPAQVTKVNSSSFEALMQDGSTVTVQWSGMSWARPYRNANSVGAAPSRA HHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCHHH SQIVKVKDIVRLRPNEAKTAWSLVQVPKVQGQLIAINPNDGSIEAIVGGYNFYQSKFNRA HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCHHHHHHHHHHH LQGWRQPGSTIKPFLYALALERGMTPYSMVNDSPITIGKWTPKNSDGRYLGMIPLRRALY HHHHHCCCCHHHHHHHHHHHHHCCCCHHHCCCCCEEEEECCCCCCCCCEEEHHHHHHHHH LSRNTVSVRLLQTVGIERTRQLFMDFGLQEDQIPRNYTIALGTPQVLPIQMATGYATFAN HCCCCEEEEEHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEECCEEEECC GGYRVQPHFIQRIEDAYGKVIYEAKPEYACIPCINAPETTDDAQVTTPDDQVVEVTNKEL CCEEECHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCCCEEECCCCHHHHHHHHHH EQKEKTTKQLNLKQTDKNNSQYRQAQRILKSSSAYDMANILRDVIEHGTGRAALKIGRSD HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCHH LGGKTGTTNDAKDAWFAGFNGKLVTVTWVGFDQPTTLGRREYGGIAALPIWINFMGQALQ CCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCHHCCCEEEHHHHHHHHHHHHC GTPAAWVRLEKDAQAPISRDKQEVTAEVGDKKTYRAAPPLARPLYRPAPPQPKTTNNDFD CCCHHEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCC DLPGEEIVIPSKTTPPAMKPSQGAAPKREKDELENLINQIE CCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC >Mature Secondary Structure MYLYIAPALPEMSSLKKAPLLKPLQVYTADNQLIAEYGGKLSIPVEYKQIPPNFIHAFLA CEEEEECCCCCHHHHHCCCCCCCEEEEECCCEEHHHCCCEEEEEEEHHHCCHHHHHHHHH AEDSSFFEHSGISFKGLGRALSESVTGSDVQTGGSTITMQVAKNYYLSPERTLKRKLTEI CCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH FLARKIEQNLSKEDILSLYVNKIFLGKNAYGIAAAAKIYYNKSINELSIAQMAMIAGLPK HHHHHHHHCCCHHHHHHHHHHHHEECCCCCCHHHHHHEEECCCCCHHHHHHHHHHHCCCC APSKYNPVVNPERALERRNWILGRMLQLGYISQTEYQKAVAEPINLNMPNRDLNNIHPYA CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHH GEMVRSELVKHFGEQAIDSGYKVYTTINAKRQAIAEKAVQDGLEAYDRRHGWRGAEAHDK HHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC PLSEFRAYANTYPAQVTKVNSSSFEALMQDGSTVTVQWSGMSWARPYRNANSVGAAPSRA HHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCHHH SQIVKVKDIVRLRPNEAKTAWSLVQVPKVQGQLIAINPNDGSIEAIVGGYNFYQSKFNRA HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCHHHHHHHHHHH LQGWRQPGSTIKPFLYALALERGMTPYSMVNDSPITIGKWTPKNSDGRYLGMIPLRRALY HHHHHCCCCHHHHHHHHHHHHHCCCCHHHCCCCCEEEEECCCCCCCCCEEEHHHHHHHHH LSRNTVSVRLLQTVGIERTRQLFMDFGLQEDQIPRNYTIALGTPQVLPIQMATGYATFAN HCCCCEEEEEHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEECCEEEECC GGYRVQPHFIQRIEDAYGKVIYEAKPEYACIPCINAPETTDDAQVTTPDDQVVEVTNKEL CCEEECHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCCCEEECCCCHHHHHHHHHH EQKEKTTKQLNLKQTDKNNSQYRQAQRILKSSSAYDMANILRDVIEHGTGRAALKIGRSD HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCHH LGGKTGTTNDAKDAWFAGFNGKLVTVTWVGFDQPTTLGRREYGGIAALPIWINFMGQALQ CCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCHHCCCEEEHHHHHHHHHHHHC GTPAAWVRLEKDAQAPISRDKQEVTAEVGDKKTYRAAPPLARPLYRPAPPQPKTTNNDFD CCCHHEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCC DLPGEEIVIPSKTTPPAMKPSQGAAPKREKDELENLINQIE CCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10984043; 7901733 [H]