Click here to switch to the map view.

The map label for this gene is mdaB [H]

Identifier: 213158902

GI number: 213158902

Start: 3710699

End: 3711286

Strand: Direct

Name: mdaB [H]

Synonym: AB57_3603

Alternate gene names: 213158902

Gene position: 3710699-3711286 (Clockwise)

Preceding gene: 213158899

Following gene: 213158903

Centisome position: 91.61

GC content: 38.95

Gene sequence:

>588_bases
ATGAGCAATATTTTAGTCATTAATGGTGCCAAACAATTTGCCCACTCAAATGGTGAATTAAATGACACACTCACGACATT
AGCGACGAATCACCTCACTGAACTCGGTCATGAAGTAAAAGTCACTCGTGCAGATAGTGACTACAATGCTGAAGCCGAAG
TAGAAAAATATTTATGGGCAGATGTCGTGATTTATCAAATGCCGGGCTGGTGGATGGGTGCACCGTGGACTGTAAAAAAA
TATATTGACGATGTATTTACGACAGGTCATGGTTCTCTTTATGCAAACGATGGTCGTAGCCGCTCTGATGCCTCAAAAAA
ATATGGTTCAGGTGGTTTAATTCATGACAAAAAATATATGTTGTCGCTTACTTGGAATGCGCCAATGGAAGCATTTGACG
ATGCGGATCAGTTTTTCCATGGTGTGGGTGTAGATGGTGTTTATTTACCATTTCATAAAGCAAATCAATTCTTAGGTATG
AGTACCCTACCAACATTTATTGTAAATGATGTAATTAAAATGCCTGATGTAGATAGTTATGTGGAAGCATACAAAGCACA
TTTGAACACACTATTTGCAGCAGCCTAA

Upstream 100 bases:

>100_bases
ATTTTTAATCAATAATATTTTTCCAATTACTACATTTTTCTTTAAGAGTAAGTTCTCTAAAGTATCGCTCAAGTTTAAGA
ATTGAATTAGAGTAACTCCC

Downstream 100 bases:

>100_bases
TCCGGAGAAAACCATGCTTACTATTATCGCGGAAATTCGTACTCAATCGGGTGGACAGCACCGCCAAAACGTATTGAATG
CATTTCAAAAAATCATTCCA

Product: modulator of drug activity B

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSNILVINGAKQFAHSNGELNDTLTTLATNHLTELGHEVKVTRADSDYNAEAEVEKYLWADVVIYQMPGWWMGAPWTVKK
YIDDVFTTGHGSLYANDGRSRSDASKKYGSGGLIHDKKYMLSLTWNAPMEAFDDADQFFHGVGVDGVYLPFHKANQFLGM
STLPTFIVNDVIKMPDVDSYVEAYKAHLNTLFAAA

Sequences:

>Translated_195_residues
MSNILVINGAKQFAHSNGELNDTLTTLATNHLTELGHEVKVTRADSDYNAEAEVEKYLWADVVIYQMPGWWMGAPWTVKK
YIDDVFTTGHGSLYANDGRSRSDASKKYGSGGLIHDKKYMLSLTWNAPMEAFDDADQFFHGVGVDGVYLPFHKANQFLGM
STLPTFIVNDVIKMPDVDSYVEAYKAHLNTLFAAA
>Mature_194_residues
SNILVINGAKQFAHSNGELNDTLTTLATNHLTELGHEVKVTRADSDYNAEAEVEKYLWADVVIYQMPGWWMGAPWTVKKY
IDDVFTTGHGSLYANDGRSRSDASKKYGSGGLIHDKKYMLSLTWNAPMEAFDDADQFFHGVGVDGVYLPFHKANQFLGMS
TLPTFIVNDVIKMPDVDSYVEAYKAHLNTLFAAA

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=193, Percent_Identity=76.1658031088083, Blast_Score=322, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 21721; Mature: 21589

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNILVINGAKQFAHSNGELNDTLTTLATNHLTELGHEVKVTRADSDYNAEAEVEKYLWA
CCCEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHH
DVVIYQMPGWWMGAPWTVKKYIDDVFTTGHGSLYANDGRSRSDASKKYGSGGLIHDKKYM
HEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHCCCCCCEECCEEE
LSLTWNAPMEAFDDADQFFHGVGVDGVYLPFHKANQFLGMSTLPTFIVNDVIKMPDVDSY
EEEEECCCHHHHCCHHHHHHCCCCCCEEECHHHCCHHCCCHHHHHHHHHHHHCCCCHHHH
VEAYKAHLNTLFAAA
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNILVINGAKQFAHSNGELNDTLTTLATNHLTELGHEVKVTRADSDYNAEAEVEKYLWA
CCEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHH
DVVIYQMPGWWMGAPWTVKKYIDDVFTTGHGSLYANDGRSRSDASKKYGSGGLIHDKKYM
HEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHCCCCCCEECCEEE
LSLTWNAPMEAFDDADQFFHGVGVDGVYLPFHKANQFLGMSTLPTFIVNDVIKMPDVDSY
EEEEECCCHHHHCCHHHHHHCCCCCCEEECHHHCCHHCCCHHHHHHHHHHHHCCCCHHHH
VEAYKAHLNTLFAAA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]