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The map label for this gene is mmgC [H]

Identifier: 213158807

GI number: 213158807

Start: 3619455

End: 3620627

Strand: Direct

Name: mmgC [H]

Synonym: AB57_3502

Alternate gene names: 213158807

Gene position: 3619455-3620627 (Clockwise)

Preceding gene: 213158801

Following gene: 213158838

Centisome position: 89.36

GC content: 39.22

Gene sequence:

>1173_bases
ATGCAATCTGGTGCTATTCGTCCCATTCCAAATATGTTACCTCGCCATTTATTTAATGAAGAACATGAAGCTTTTCGGGA
AACGGTACGTAAATTCTATGAGAAAGAAGTTGTACCTAATATTGAAAAATATGAAAAACAACAACATGTTGACCGAGATC
TTTGGAATAAAGCTGGTGCATTAGGTTTACTCTGTACCACCATGCCAGAACAATATGGTGGTTCAGGTGTGGATCGCCTA
TACAGCATGATTCTTATTGAAGAACAAGCCTATGCGATGGACTCAAGTACAGGTTTCTCACTGCATTCCGACATTGTAGC
CAACTATATTAATAACTTCGGTAATGAAGAGCAAAAACAGAAATGGCTCCCTAAAATGGCTACTGGTGAGACGGTTACCG
CAATTGCCATGACCGAGCCGGGAACAGGTTCAGACTTGCAAGCGGTTCGTACAACAGCCGTTCTTGATGGCGATGAATAT
GTCATTAATGGTTCAAAAATATTTATTACCAATGGCTATTTATGCGATATGGCGATTGTCGTTTGTAAAACGGGGAATAG
CGATAAAGGATCTGCCAATTTATCACTCATTATTGTCGAAGCTGACCGTGCTGGTTTTACTAAGGGCAAACCACTTAACA
AAATTGGTATGAAAGGCCAAGATACCTGTGAACTCTTCTTTGATAACGTTCGTGTTCCTAAAGAAAATCTTTTAGGTATG
GAAGGTATGGGCTTTATCATGCTCATGAAAGAATTAGCGTGGGAGCGTATGCTAGTTGCTATTATCTGCCAAGCCGGGGC
AGAAGCAGCATTTGCACATACTGTTCAATATACAAAAGATCGTAAAGCATTCGGCAAACCAATTGGAGCATTCCAAAATA
CTCGTTTTAAACTTGCTGAACTTAGAACAGAGATAGATTTCTGCCGTACCTATTTAGATCGTTGTATGGAATTACAACTC
GATGAAAAATTGAGTGTTGAAGCTGCAGCGGCTGCAAAATATAAAATTTCAGATATGTTTTCAAAAGTTGTAGATGAATG
TCTTCAATTACATGGTGGTTATGGCTATATGCTGGAATATCCAATTGCCCGCGCTTATATCGATCACCGAGCAAACCGTA
TTTATGCAGGCACCAATGAAATTATGAAAGAATTAATCTCTAGAACTCTTTAA

Upstream 100 bases:

>100_bases
CACTTCACCGCCATAAATGAGCATTCATCACATTGTTAGGTCTAGTCGCTTCCCTTATGTTTAGCTCATAACATCAAGCC
CAAACCAAGGAAGAAATACA

Downstream 100 bases:

>100_bases
TCTTTACTATAAAAAAGGAGGCTTATAGCCTCCTTTTTATTTTCGAATATCAAGACACTAATTTTGGTTTACGTGTGGTA
ACTTCTGAATGCTTATGAAA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MQSGAIRPIPNMLPRHLFNEEHEAFRETVRKFYEKEVVPNIEKYEKQQHVDRDLWNKAGALGLLCTTMPEQYGGSGVDRL
YSMILIEEQAYAMDSSTGFSLHSDIVANYINNFGNEEQKQKWLPKMATGETVTAIAMTEPGTGSDLQAVRTTAVLDGDEY
VINGSKIFITNGYLCDMAIVVCKTGNSDKGSANLSLIIVEADRAGFTKGKPLNKIGMKGQDTCELFFDNVRVPKENLLGM
EGMGFIMLMKELAWERMLVAIICQAGAEAAFAHTVQYTKDRKAFGKPIGAFQNTRFKLAELRTEIDFCRTYLDRCMELQL
DEKLSVEAAAAAKYKISDMFSKVVDECLQLHGGYGYMLEYPIARAYIDHRANRIYAGTNEIMKELISRTL

Sequences:

>Translated_390_residues
MQSGAIRPIPNMLPRHLFNEEHEAFRETVRKFYEKEVVPNIEKYEKQQHVDRDLWNKAGALGLLCTTMPEQYGGSGVDRL
YSMILIEEQAYAMDSSTGFSLHSDIVANYINNFGNEEQKQKWLPKMATGETVTAIAMTEPGTGSDLQAVRTTAVLDGDEY
VINGSKIFITNGYLCDMAIVVCKTGNSDKGSANLSLIIVEADRAGFTKGKPLNKIGMKGQDTCELFFDNVRVPKENLLGM
EGMGFIMLMKELAWERMLVAIICQAGAEAAFAHTVQYTKDRKAFGKPIGAFQNTRFKLAELRTEIDFCRTYLDRCMELQL
DEKLSVEAAAAAKYKISDMFSKVVDECLQLHGGYGYMLEYPIARAYIDHRANRIYAGTNEIMKELISRTL
>Mature_390_residues
MQSGAIRPIPNMLPRHLFNEEHEAFRETVRKFYEKEVVPNIEKYEKQQHVDRDLWNKAGALGLLCTTMPEQYGGSGVDRL
YSMILIEEQAYAMDSSTGFSLHSDIVANYINNFGNEEQKQKWLPKMATGETVTAIAMTEPGTGSDLQAVRTTAVLDGDEY
VINGSKIFITNGYLCDMAIVVCKTGNSDKGSANLSLIIVEADRAGFTKGKPLNKIGMKGQDTCELFFDNVRVPKENLLGM
EGMGFIMLMKELAWERMLVAIICQAGAEAAFAHTVQYTKDRKAFGKPIGAFQNTRFKLAELRTEIDFCRTYLDRCMELQL
DEKLSVEAAAAAKYKISDMFSKVVDECLQLHGGYGYMLEYPIARAYIDHRANRIYAGTNEIMKELISRTL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=391, Percent_Identity=46.2915601023018, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=33.42175066313, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=33.0687830687831, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=34.9462365591398, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=34.6041055718475, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI21361497, Length=396, Percent_Identity=34.3434343434343, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=31.7460317460317, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=31.7460317460317, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI76496475, Length=396, Percent_Identity=33.5858585858586, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4557235, Length=396, Percent_Identity=33.5858585858586, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4501859, Length=394, Percent_Identity=28.9340101522843, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4503943, Length=379, Percent_Identity=26.9129287598945, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI7669494, Length=364, Percent_Identity=26.9230769230769, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI48976061, Length=387, Percent_Identity=26.6149870801034, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI211971008, Length=387, Percent_Identity=26.6149870801034, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38505218, Length=382, Percent_Identity=27.2251308900524, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI87081958, Length=335, Percent_Identity=33.134328358209, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1786223, Length=382, Percent_Identity=27.4869109947644, Blast_Score=124, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17538396, Length=402, Percent_Identity=34.3283582089552, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17551932, Length=377, Percent_Identity=33.6870026525199, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17533517, Length=369, Percent_Identity=32.7913279132791, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17534899, Length=362, Percent_Identity=33.1491712707182, Blast_Score=204, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=32.9787234042553, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17508101, Length=376, Percent_Identity=30.8510638297872, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17570075, Length=372, Percent_Identity=31.989247311828, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=31.758530183727, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17506239, Length=378, Percent_Identity=30.952380952381, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI71985184, Length=392, Percent_Identity=32.6530612244898, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=35.7664233576642, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI71982178, Length=278, Percent_Identity=30.2158273381295, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=300, Percent_Identity=33.6666666666667, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17534353, Length=381, Percent_Identity=26.509186351706, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32563615, Length=226, Percent_Identity=34.070796460177, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17562446, Length=365, Percent_Identity=28.2191780821918, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=24.3801652892562, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=36.2924281984334, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI21356377, Length=374, Percent_Identity=32.3529411764706, Blast_Score=211, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24666513, Length=391, Percent_Identity=30.690537084399, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=31.283422459893, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24660351, Length=376, Percent_Identity=32.1808510638298, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI281363737, Length=353, Percent_Identity=30.028328611898, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI19920834, Length=387, Percent_Identity=29.4573643410853, Blast_Score=137, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43815; Mature: 43815

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSGAIRPIPNMLPRHLFNEEHEAFRETVRKFYEKEVVPNIEKYEKQQHVDRDLWNKAGA
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
LGLLCTTMPEQYGGSGVDRLYSMILIEEQAYAMDSSTGFSLHSDIVANYINNFGNEEQKQ
HHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHH
KWLPKMATGETVTAIAMTEPGTGSDLQAVRTTAVLDGDEYVINGSKIFITNGYLCDMAIV
HHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHEECCCEEEEECCEEEEECCHHHEEEEE
VCKTGNSDKGSANLSLIIVEADRAGFTKGKPLNKIGMKGQDTCELFFDNVRVPKENLLGM
EEECCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHCCCCCHHHCCCC
EGMGFIMLMKELAWERMLVAIICQAGAEAAFAHTVQYTKDRKAFGKPIGAFQNTRFKLAE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LRTEIDFCRTYLDRCMELQLDEKLSVEAAAAAKYKISDMFSKVVDECLQLHGGYGYMLEY
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHH
PIARAYIDHRANRIYAGTNEIMKELISRTL
HHHHHHHHHCCCEEEECHHHHHHHHHHHCC
>Mature Secondary Structure
MQSGAIRPIPNMLPRHLFNEEHEAFRETVRKFYEKEVVPNIEKYEKQQHVDRDLWNKAGA
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
LGLLCTTMPEQYGGSGVDRLYSMILIEEQAYAMDSSTGFSLHSDIVANYINNFGNEEQKQ
HHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHH
KWLPKMATGETVTAIAMTEPGTGSDLQAVRTTAVLDGDEYVINGSKIFITNGYLCDMAIV
HHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHEECCCEEEEECCEEEEECCHHHEEEEE
VCKTGNSDKGSANLSLIIVEADRAGFTKGKPLNKIGMKGQDTCELFFDNVRVPKENLLGM
EEECCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHCCCCCHHHCCCC
EGMGFIMLMKELAWERMLVAIICQAGAEAAFAHTVQYTKDRKAFGKPIGAFQNTRFKLAE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LRTEIDFCRTYLDRCMELQLDEKLSVEAAAAAKYKISDMFSKVVDECLQLHGGYGYMLEY
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHH
PIARAYIDHRANRIYAGTNEIMKELISRTL
HHHHHHHHHCCCEEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]