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The map label for this gene is ycgM [H]

Identifier: 213158793

GI number: 213158793

Start: 3601662

End: 3602303

Strand: Reverse

Name: ycgM [H]

Synonym: AB57_3488

Alternate gene names: 213158793

Gene position: 3602303-3601662 (Counterclockwise)

Preceding gene: 213158794

Following gene: 213158791

Centisome position: 88.93

GC content: 39.56

Gene sequence:

>642_bases
ATGAAAACACGTCCTTCAAAAATCGTTTGTGTGGGCAGAAGTTATGCTGATCATGTAAAAGAACTGAACAATGCAATGCC
AGGACGTCCGGTGTTATTTATCAAACCACCAAGTAGTTTGATTGGTTTAGATGAAGGCATTTCATGGAATCCTGCATGGG
GTAGTTGTCATTTCGAATGCGAATTTGTTTTACGCATTGATCAGCCACTAAAAGGAGAAACTGATCCGCAAAAAGTATTG
CAGGCCATTGGTGCAGTGACTTTAGGATTGGATTTAACATTACGTGACTTACAAAATGAGTTAAAAGATAAAGGCCAACC
TTGGGAAAGAGCAAAGGCTTTTGATGGTTCGTGTGTGCTTGCAGACTGGGTAGATGTGAGTGAAATCACGAACTGGGAAG
AGACTAGATTTAATTTCCATATTAATGATGAATTACGTCAAGACGGTAATACCGCTTTGCTCATGTTTAATATTGCTTAT
CTTTTAGTAGATATTAATCAGGTGTTCTCACTTGAGCCAGGCGATGTCATTATGACGGGTACACCCGCAGGTGTAGGACC
ATTAAATGCTGGCGATCAGCTAAAAATGACTTTGAAAGGGGCTACTCAAGATTTTGTTTGGGAAACTTTTGTTAAAGCAT
AA

Upstream 100 bases:

>100_bases
GAAACGTGCATTTGCTCAGGCTTCAGATCAAACTATATTTGAAAATACATTTAAGAAATAAGTTATTGGAATTATTAGCC
GCAACAATAAAGGAAGCTTC

Downstream 100 bases:

>100_bases
TTTTATTTAAGTTATTAAACTTTAAACCCTATTATTAAACGGATAATAGGGTTTTTTTATTATACTCAAAATTAATTTAT
TGATAGAGCTTTCGGAACTG

Product: fumarylacetoacetate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKTRPSKIVCVGRSYADHVKELNNAMPGRPVLFIKPPSSLIGLDEGISWNPAWGSCHFECEFVLRIDQPLKGETDPQKVL
QAIGAVTLGLDLTLRDLQNELKDKGQPWERAKAFDGSCVLADWVDVSEITNWEETRFNFHINDELRQDGNTALLMFNIAY
LLVDINQVFSLEPGDVIMTGTPAGVGPLNAGDQLKMTLKGATQDFVWETFVKA

Sequences:

>Translated_213_residues
MKTRPSKIVCVGRSYADHVKELNNAMPGRPVLFIKPPSSLIGLDEGISWNPAWGSCHFECEFVLRIDQPLKGETDPQKVL
QAIGAVTLGLDLTLRDLQNELKDKGQPWERAKAFDGSCVLADWVDVSEITNWEETRFNFHINDELRQDGNTALLMFNIAY
LLVDINQVFSLEPGDVIMTGTPAGVGPLNAGDQLKMTLKGATQDFVWETFVKA
>Mature_213_residues
MKTRPSKIVCVGRSYADHVKELNNAMPGRPVLFIKPPSSLIGLDEGISWNPAWGSCHFECEFVLRIDQPLKGETDPQKVL
QAIGAVTLGLDLTLRDLQNELKDKGQPWERAKAFDGSCVLADWVDVSEITNWEETRFNFHINDELRQDGNTALLMFNIAY
LLVDINQVFSLEPGDVIMTGTPAGVGPLNAGDQLKMTLKGATQDFVWETFVKA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI66348062, Length=198, Percent_Identity=35.3535353535354, Blast_Score=142, Evalue=2e-34,
Organism=Homo sapiens, GI215422413, Length=193, Percent_Identity=35.7512953367876, Blast_Score=141, Evalue=3e-34,
Organism=Homo sapiens, GI13654274, Length=193, Percent_Identity=35.7512953367876, Blast_Score=141, Evalue=4e-34,
Organism=Homo sapiens, GI156231349, Length=185, Percent_Identity=32.4324324324324, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI40786394, Length=185, Percent_Identity=30.8108108108108, Blast_Score=91, Evalue=7e-19,
Organism=Escherichia coli, GI1787428, Length=198, Percent_Identity=43.4343434343434, Blast_Score=174, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17557057, Length=193, Percent_Identity=40.9326424870466, Blast_Score=146, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6324161, Length=223, Percent_Identity=36.7713004484305, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571789, Length=189, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28572127, Length=185, Percent_Identity=29.1891891891892, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24663695, Length=183, Percent_Identity=28.9617486338798, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23690; Mature: 23690

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRPSKIVCVGRSYADHVKELNNAMPGRPVLFIKPPSSLIGLDEGISWNPAWGSCHFEC
CCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHEECCCCCCCCCCCCCEEEEE
EFVLRIDQPLKGETDPQKVLQAIGAVTLGLDLTLRDLQNELKDKGQPWERAKAFDGSCVL
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCHHHHHCCCCCEEE
ADWVDVSEITNWEETRFNFHINDELRQDGNTALLMFNIAYLLVDINQVFSLEPGDVIMTG
ECCCCHHHHCCCCCEEEEEEECHHHHCCCCEEEEHEEHHHHHHHHHHHHCCCCCCEEEEC
TPAGVGPLNAGDQLKMTLKGATQDFVWETFVKA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MKTRPSKIVCVGRSYADHVKELNNAMPGRPVLFIKPPSSLIGLDEGISWNPAWGSCHFEC
CCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHEECCCCCCCCCCCCCEEEEE
EFVLRIDQPLKGETDPQKVLQAIGAVTLGLDLTLRDLQNELKDKGQPWERAKAFDGSCVL
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCHHHHHCCCCCEEE
ADWVDVSEITNWEETRFNFHINDELRQDGNTALLMFNIAYLLVDINQVFSLEPGDVIMTG
ECCCCHHHHCCCCCEEEEEEECHHHHCCCCEEEEHEEHHHHHHHHHHHHCCCCCCEEEEC
TPAGVGPLNAGDQLKMTLKGATQDFVWETFVKA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]