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The map label for this gene is dapB

Identifier: 213158765

GI number: 213158765

Start: 4020208

End: 4021029

Strand: Reverse

Name: dapB

Synonym: AB57_3899

Alternate gene names: 213158765

Gene position: 4021029-4020208 (Counterclockwise)

Preceding gene: 213158767

Following gene: 213158764

Centisome position: 99.27

GC content: 45.62

Gene sequence:

>822_bases
ATGTCAGCAGCTCCACGCATTGGTATTTTGGGTGCAGGCGGCCGTATGGGTCGTATACTTATTCAGGCAGTTCAACAAGC
AGGTTATCAATTGGGAGCCGCTGTTGTACGCCCAGAAAGTACTTTAATCGGTGCTGATGCTGGTGAACTTGCAGGAATTG
GTTCAATTGGAGTGAAGCTTACCGGAAGCTTGGCAGAGGTTCTTGAAGACTGTGATGTTGTAATTGACTTTTCGACTCCT
GCAGCAACATCTGAGCATTTAAAGCTATGTCGTGAAGCTGGTGTAGCTATAGTGATTGGGACAACGGGAATGTCTGATGA
ACAAAAAGCTGAGCTTGATGAAACGGCAAAACATATACCTGTTGTATATGCTGCGAACTACTCTGTTGGCGTAAATGTAT
CAATCAAGTTACTTGAGCTTGCAGCAAAAGTATTTGGCGATACAGTAGATATTGAAGTGATTGAGGCTCATCACCGTCAT
AAAGTAGATGCACCATCTGGTACTGCATTAATGATGGGTGAAGCAATTGCGGATACGTTAGGCCGTAACTTAAAAGAAGT
TGCTGTTTATGGTCGTGAAGGGCATACCGGTCCACGTGATCGTCAAACCATTGGTTTCGAAACCATCCGTGGTGGCGATA
TTGTAGGGGAACATACGGTCATGTTTATTGGTGAGGGTGAGCGTGTTGAAGTGACTCACAAAGCCACTAACCGTATGAAC
TTTGCTGCCGGTGCAGTACGAGCTGCTGCATGGGTTGTGGGCCGTGAAGCGCGTAAATATGACATGAAAGATGTTTTAGG
GTTGAACGACGTACAGGTGTAA

Upstream 100 bases:

>100_bases
AATTCCCGTTCCCTTTAAAAAATATTTTTTACTTTTTATTGTGGGCAAAGAGTTTTGATATAGTAAGCCAATTACGTAAA
ACAGAAGATTGGGAAGGATT

Downstream 100 bases:

>100_bases
ACCATCTGTACACTTCCCATATGTGGCGAGAAAAACAAGATAGAGCAGAACATGAATAAAAAACAAATTGCTTTGACCAC
TCTTCTTTGCTTAAGCAGCC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSAAPRIGILGAGGRMGRILIQAVQQAGYQLGAAVVRPESTLIGADAGELAGIGSIGVKLTGSLAEVLEDCDVVIDFSTP
AATSEHLKLCREAGVAIVIGTTGMSDEQKAELDETAKHIPVVYAANYSVGVNVSIKLLELAAKVFGDTVDIEVIEAHHRH
KVDAPSGTALMMGEAIADTLGRNLKEVAVYGREGHTGPRDRQTIGFETIRGGDIVGEHTVMFIGEGERVEVTHKATNRMN
FAAGAVRAAAWVVGREARKYDMKDVLGLNDVQV

Sequences:

>Translated_273_residues
MSAAPRIGILGAGGRMGRILIQAVQQAGYQLGAAVVRPESTLIGADAGELAGIGSIGVKLTGSLAEVLEDCDVVIDFSTP
AATSEHLKLCREAGVAIVIGTTGMSDEQKAELDETAKHIPVVYAANYSVGVNVSIKLLELAAKVFGDTVDIEVIEAHHRH
KVDAPSGTALMMGEAIADTLGRNLKEVAVYGREGHTGPRDRQTIGFETIRGGDIVGEHTVMFIGEGERVEVTHKATNRMN
FAAGAVRAAAWVVGREARKYDMKDVLGLNDVQV
>Mature_272_residues
SAAPRIGILGAGGRMGRILIQAVQQAGYQLGAAVVRPESTLIGADAGELAGIGSIGVKLTGSLAEVLEDCDVVIDFSTPA
ATSEHLKLCREAGVAIVIGTTGMSDEQKAELDETAKHIPVVYAANYSVGVNVSIKLLELAAKVFGDTVDIEVIEAHHRHK
VDAPSGTALMMGEAIADTLGRNLKEVAVYGREGHTGPRDRQTIGFETIRGGDIVGEHTVMFIGEGERVEVTHKATNRMNF
AAGAVRAAAWVVGREARKYDMKDVLGLNDVQV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=60.2996254681648, Blast_Score=306, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_ACIB3 (B7GV10)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002323979.1
- ProteinModelPortal:   B7GV10
- SMR:   B7GV10
- GeneID:   7059336
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_000038
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28753; Mature: 28622

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAPRIGILGAGGRMGRILIQAVQQAGYQLGAAVVRPESTLIGADAGELAGIGSIGVKL
CCCCCCEEEEECCCHHHHHHHHHHHHCCHHHCEEEECCCCEEEECCCHHHCCCCCCCEEE
TGSLAEVLEDCDVVIDFSTPAATSEHLKLCREAGVAIVIGTTGMSDEQKAELDETAKHIP
CCHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCC
VVYAANYSVGVNVSIKLLELAAKVFGDTVDIEVIEAHHRHKVDAPSGTALMMGEAIADTL
EEEEECCEECCCEEHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCCCCEEEHHHHHHHHH
GRNLKEVAVYGREGHTGPRDRQTIGFETIRGGDIVGEHTVMFIGEGERVEVTHKATNRMN
CCCHHHHEEECCCCCCCCCCCCEECEEEECCCCEECCEEEEEEECCCEEEEEECCCCCCH
FAAGAVRAAAWVVGREARKYDMKDVLGLNDVQV
HHHHHHHHHHHHHHCHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure 
SAAPRIGILGAGGRMGRILIQAVQQAGYQLGAAVVRPESTLIGADAGELAGIGSIGVKL
CCCCCEEEEECCCHHHHHHHHHHHHCCHHHCEEEECCCCEEEECCCHHHCCCCCCCEEE
TGSLAEVLEDCDVVIDFSTPAATSEHLKLCREAGVAIVIGTTGMSDEQKAELDETAKHIP
CCHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCC
VVYAANYSVGVNVSIKLLELAAKVFGDTVDIEVIEAHHRHKVDAPSGTALMMGEAIADTL
EEEEECCEECCCEEHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCCCCEEEHHHHHHHHH
GRNLKEVAVYGREGHTGPRDRQTIGFETIRGGDIVGEHTVMFIGEGERVEVTHKATNRMN
CCCHHHHEEECCCCCCCCCCCCEECEEEECCCCEECCEEEEEEECCCEEEEEECCCCCCH
FAAGAVRAAAWVVGREARKYDMKDVLGLNDVQV
HHHHHHHHHHHHHHCHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA