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The map label for this gene is mdtA [H]

Identifier: 213158704

GI number: 213158704

Start: 2748858

End: 2750078

Strand: Direct

Name: mdtA [H]

Synonym: AB57_2662

Alternate gene names: 213158704

Gene position: 2748858-2750078 (Clockwise)

Preceding gene: 213158698

Following gene: 213158705

Centisome position: 67.86

GC content: 44.47

Gene sequence:

>1221_bases
ATGTCATTTTCCCGCAAACAGTTTGCACTGTCTGCCATCTTTGTCGCTATTTTAGCAACCGGTGGCAGTTTTATGTTGTT
ACATGAAAATGCCGATGCAAAAGCTGCACCAACCGCTGCCCAACAAGCTGCTACTGTTGATGTAGCCCCAGTAGTAAGCA
AAACCATTACCGATTGGCAAGAATATTCCGGTCGTTTAGAAGCAATTGATCAAGTTGATATTCGGCCTCAAGTTTCAGGA
AAACTTATTGCCGTACATTTCAAAGATGGAAGCCTCGTTAAAAAAGGTGATTTACTTTTCACAATCGACCCTCGTCCTTT
TGAAGCAGAACTGAACCGTGCAAAAGCCCAACTTGCTTCAGCTGAAGCACAGGTAACATATACCGCAAGCAATCTTTCGC
GTATTCAACGTCTCATTCAGAGTAATGCTGTTTCTCGCCAAGAACTGGATTTAGCCGAAAATGATGCACGTTCAGCGAAT
GCTAACCTACAAGCCGCTAGAGCTGCTGTCCAATCTGCACGTTTAAATCTAGAATACACCCGTATTACAGCACCTGTCAG
CGGCCGGATTTCACGAGCTGAAGTCACCGTTGGTAATGTAGTTTCTGCAGGTAACGGCGCACAGGTTTTAACAAGTTTAG
TGTCTGTATCCCGCCTTTATGCATCTTTCGATGTTGATGAACAAACTTACCTGAAATATATCAGTAATCAGCGTAATTCA
GCACAAGTACCTGTCTATATGGGACTTGCCAATGAAACAGGCTTTACTCGTGAAGGTACAATCAACTCAATCGATAACAA
TCTGAATACAACCTCAGGTACGATCCGTGTTCGCGCAACTTTTGACAATCCAAACGGTGTTTTATTACCAGGCCTATATG
CACGAATTCGTTTAGGTGGAGGCCAACCTCGCCCAGCGATTCTGATTAGTCCAACCGCGGTTGGTGTCGACCAAGATAAA
CGTTTTGTCGTAGTAGTAGATGCGAAAAATCAAACTGCTTATCGCGAAGTAAAACTCGGTGCCCAACAAGATGGCTTGCA
AATCGTAAATAGCGGATTACAAGCGGGTGATCGTATTGTAGTGAATGGTTTACAACGGATTCGTCCGGGTGACCCTGTTA
CACCGCATCTCGTCCCTATGCCAAATTCACAAATCACTGCTAGCGCTACTCCTCCTCAACCTCAGCCAACAGATAAAACA
TCAACTCCGGCAAAAGGTTAA

Upstream 100 bases:

>100_bases
ACAAACTTTTATGCTCCGTCCATTCCATAAACCCTGTTTCTCCCATACGGACCATAACTAAAAGTCTGAAAACAGGTATC
CAAATAACTAGGAGCACCTC

Downstream 100 bases:

>100_bases
TCACATATGAATATTTCTAAATTTTTTATTGATCGGCCGATCTTTGCTGGTGTGCTATCAGTCTTGATTTTACTCGCCGG
TCTCCTTTCGGTATTTCAGT

Product: efflux transporter, RND family

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSFSRKQFALSAIFVAILATGGSFMLLHENADAKAAPTAAQQAATVDVAPVVSKTITDWQEYSGRLEAIDQVDIRPQVSG
KLIAVHFKDGSLVKKGDLLFTIDPRPFEAELNRAKAQLASAEAQVTYTASNLSRIQRLIQSNAVSRQELDLAENDARSAN
ANLQAARAAVQSARLNLEYTRITAPVSGRISRAEVTVGNVVSAGNGAQVLTSLVSVSRLYASFDVDEQTYLKYISNQRNS
AQVPVYMGLANETGFTREGTINSIDNNLNTTSGTIRVRATFDNPNGVLLPGLYARIRLGGGQPRPAILISPTAVGVDQDK
RFVVVVDAKNQTAYREVKLGAQQDGLQIVNSGLQAGDRIVVNGLQRIRPGDPVTPHLVPMPNSQITASATPPQPQPTDKT
STPAKG

Sequences:

>Translated_406_residues
MSFSRKQFALSAIFVAILATGGSFMLLHENADAKAAPTAAQQAATVDVAPVVSKTITDWQEYSGRLEAIDQVDIRPQVSG
KLIAVHFKDGSLVKKGDLLFTIDPRPFEAELNRAKAQLASAEAQVTYTASNLSRIQRLIQSNAVSRQELDLAENDARSAN
ANLQAARAAVQSARLNLEYTRITAPVSGRISRAEVTVGNVVSAGNGAQVLTSLVSVSRLYASFDVDEQTYLKYISNQRNS
AQVPVYMGLANETGFTREGTINSIDNNLNTTSGTIRVRATFDNPNGVLLPGLYARIRLGGGQPRPAILISPTAVGVDQDK
RFVVVVDAKNQTAYREVKLGAQQDGLQIVNSGLQAGDRIVVNGLQRIRPGDPVTPHLVPMPNSQITASATPPQPQPTDKT
STPAKG
>Mature_405_residues
SFSRKQFALSAIFVAILATGGSFMLLHENADAKAAPTAAQQAATVDVAPVVSKTITDWQEYSGRLEAIDQVDIRPQVSGK
LIAVHFKDGSLVKKGDLLFTIDPRPFEAELNRAKAQLASAEAQVTYTASNLSRIQRLIQSNAVSRQELDLAENDARSANA
NLQAARAAVQSARLNLEYTRITAPVSGRISRAEVTVGNVVSAGNGAQVLTSLVSVSRLYASFDVDEQTYLKYISNQRNSA
QVPVYMGLANETGFTREGTINSIDNNLNTTSGTIRVRATFDNPNGVLLPGLYARIRLGGGQPRPAILISPTAVGVDQDKR
FVVVVDAKNQTAYREVKLGAQQDGLQIVNSGLQAGDRIVVNGLQRIRPGDPVTPHLVPMPNSQITASATPPQPQPTDKTS
TPAKG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=377, Percent_Identity=33.42175066313, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI87082036, Length=344, Percent_Identity=33.7209302325581, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1786668, Length=389, Percent_Identity=33.6760925449871, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789665, Length=337, Percent_Identity=33.5311572700297, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI87081796, Length=316, Percent_Identity=29.1139240506329, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI87081951, Length=184, Percent_Identity=36.9565217391304, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790519, Length=249, Percent_Identity=28.5140562248996, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789637, Length=251, Percent_Identity=30.2788844621514, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43443; Mature: 43311

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSRKQFALSAIFVAILATGGSFMLLHENADAKAAPTAAQQAATVDVAPVVSKTITDWQ
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHCEEEHHHHHHHHHHHHH
EYSGRLEAIDQVDIRPQVSGKLIAVHFKDGSLVKKGDLLFTIDPRPFEAELNRAKAQLAS
HHCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEECCEEEEECCCCCHHHHHHHHHHHHC
AEAQVTYTASNLSRIQRLIQSNAVSRQELDLAENDARSANANLQAARAAVQSARLNLEYT
CCEEEEEEHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEE
RITAPVSGRISRAEVTVGNVVSAGNGAQVLTSLVSVSRLYASFDVDEQTYLKYISNQRNS
EEECCCCCCCEEEEEEECCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
AQVPVYMGLANETGFTREGTINSIDNNLNTTSGTIRVRATFDNPNGVLLPGLYARIRLGG
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCEEEEEECC
GQPRPAILISPTAVGVDQDKRFVVVVDAKNQTAYREVKLGAQQDGLQIVNSGLQAGDRIV
CCCCCEEEECCCEECCCCCCEEEEEEECCCCCCHHHEECCCCCCCHHHHHHHHCCCCEEE
VNGLQRIRPGDPVTPHLVPMPNSQITASATPPQPQPTDKTSTPAKG
EEHHHHCCCCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFSRKQFALSAIFVAILATGGSFMLLHENADAKAAPTAAQQAATVDVAPVVSKTITDWQ
CCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHCEEEHHHHHHHHHHHHH
EYSGRLEAIDQVDIRPQVSGKLIAVHFKDGSLVKKGDLLFTIDPRPFEAELNRAKAQLAS
HHCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEECCEEEEECCCCCHHHHHHHHHHHHC
AEAQVTYTASNLSRIQRLIQSNAVSRQELDLAENDARSANANLQAARAAVQSARLNLEYT
CCEEEEEEHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEE
RITAPVSGRISRAEVTVGNVVSAGNGAQVLTSLVSVSRLYASFDVDEQTYLKYISNQRNS
EEECCCCCCCEEEEEEECCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
AQVPVYMGLANETGFTREGTINSIDNNLNTTSGTIRVRATFDNPNGVLLPGLYARIRLGG
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCEEEEEECC
GQPRPAILISPTAVGVDQDKRFVVVVDAKNQTAYREVKLGAQQDGLQIVNSGLQAGDRIV
CCCCCEEEECCCEECCCCCCEEEEEEECCCCCCHHHEECCCCCCCHHHHHHHHCCCCEEE
VNGLQRIRPGDPVTPHLVPMPNSQITASATPPQPQPTDKTSTPAKG
EEHHHHCCCCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA