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The map label for this gene is ygjG [C]

Identifier: 213158640

GI number: 213158640

Start: 2685093

End: 2686469

Strand: Reverse

Name: ygjG [C]

Synonym: AB57_2594

Alternate gene names: 213158640

Gene position: 2686469-2685093 (Counterclockwise)

Preceding gene: 213158642

Following gene: 213158639

Centisome position: 66.32

GC content: 44.01

Gene sequence:

>1377_bases
ATGTTTGATACGGATAAATTCAGCGACTCTGAACATACTTTGGATGCGGTTCAAACCAATAATAATATGCATATAAATTA
TCAGGCGCACTGGATGCCTTTTTCAGCAAACCGAAACTTTGCTAAAGACCCACGTATGATTGTGGGTGCCAAAGGATCGT
ACCTAATTGATGATTCGGGCCGTGAAATATTCGATTCACTTTCAGGCTTATGGACGTGTGGTGCAGGCCATACCTTGCCT
GAAATTCAACAAGCGGTAAGTACTCAATTAGGTCAGCTCGACTACTCACCAGCGTTCCAGTTTGGTCATCCGCTTTCTTT
TAAGTTGGCAGATAAAATTGTTCAACATATGCCCGAAAAACTACAACACGTTTTCTTTACCAACTCGGGTTCGGAGTCGG
CAGATACGTCTATAAAAATGGCACGCGCCTATTGGCGCATTAAAGGTAAACCAAGTAAAACCAAATTGATTGGTCGTGCC
CGTGGCTATCATGGTGTGAACGTTGCAGGGACAAGTTTAGGTGGGATTGGCGGCAACCGTAAAATGTTTGGACAACTTAT
GGATGTAGACCATTTACCTCATACTTTGCAACCTGATTTAACTTTTACCAAAGGCTGTGCAGAAACAGGCGGGGTAGAAC
TTGCCAATGAAATGCTTAAGTTAATTGAGCTGCACGATGCTTCAAATATTGCAGCTGTCATTGTGGAGCCTATTTCCGGT
TCTGCAGGTTGTATTGTGCCGCCAACAGGCTATTTACAACGTTTAAGAGAGATCTGTGATCAGCATGACATCTTGTTAAT
TTTTGATGAGGTGATTACAGGCTTTGGGCGTTTAGGAACGTGGACGGCGGCAGAATATTTTGGGGTAACACCAGATATTT
TGAATTTTGCGAAACAGGTGACCAATGGTGCTATTCCTTTAGGTGGAGTGGTGGCAAGCCATGAAATTTACTCTGCCTTT
ATGCAGCAAGACTTACCAGAGCATGCCATTGAATTTACCCACGGCTATACCTATTCGGCACATCCAGTTGCTTGTGCTGC
CGCTTTAGCTGCCCTTGAAATTTTAGAGAAGAAAAACCTGTTGGCTCAATCGGCAGCATTGGCACCAAGTTTTGAAAAAA
TGCTGCATGGTTTAAAAAGCGCACCGCATATTTTAGATATTCGCAACTGTGGCTTGATTGGTGCTTTGCAGTTAGCTCCG
CGTGATGGCGATGCCACCATCCGAGGCTTTGAGCTTGGTATGAAACTCTGGAAAGAAGGTTTCTATGTCCGCTTTGGAGG
CGACACGCTTCAGTTCGGTCCAATGTTTAACAGTACAGAAGCAGATATTGACCGCTTAATGAATGCTGTGGGCGATGCGC
TTTATCAAGTGAATTAA

Upstream 100 bases:

>100_bases
GTTTTGTTTTTTTAAATCTAAACTCAAGATAATTTGAATTTATCAAACTTATCTCGCTATGTACACTCAAACCATAATTT
GAAAATAAACAGGAATGGTT

Downstream 100 bases:

>100_bases
GCTTTATTAGGCATTTTACCGAGGTCTGTAATATCAACAGACCCATCTTCAAAATCTAAATGAAAAATACAGTTTGATCT
GAAAACTAATTGTAGTAAGG

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MFDTDKFSDSEHTLDAVQTNNNMHINYQAHWMPFSANRNFAKDPRMIVGAKGSYLIDDSGREIFDSLSGLWTCGAGHTLP
EIQQAVSTQLGQLDYSPAFQFGHPLSFKLADKIVQHMPEKLQHVFFTNSGSESADTSIKMARAYWRIKGKPSKTKLIGRA
RGYHGVNVAGTSLGGIGGNRKMFGQLMDVDHLPHTLQPDLTFTKGCAETGGVELANEMLKLIELHDASNIAAVIVEPISG
SAGCIVPPTGYLQRLREICDQHDILLIFDEVITGFGRLGTWTAAEYFGVTPDILNFAKQVTNGAIPLGGVVASHEIYSAF
MQQDLPEHAIEFTHGYTYSAHPVACAAALAALEILEKKNLLAQSAALAPSFEKMLHGLKSAPHILDIRNCGLIGALQLAP
RDGDATIRGFELGMKLWKEGFYVRFGGDTLQFGPMFNSTEADIDRLMNAVGDALYQVN

Sequences:

>Translated_458_residues
MFDTDKFSDSEHTLDAVQTNNNMHINYQAHWMPFSANRNFAKDPRMIVGAKGSYLIDDSGREIFDSLSGLWTCGAGHTLP
EIQQAVSTQLGQLDYSPAFQFGHPLSFKLADKIVQHMPEKLQHVFFTNSGSESADTSIKMARAYWRIKGKPSKTKLIGRA
RGYHGVNVAGTSLGGIGGNRKMFGQLMDVDHLPHTLQPDLTFTKGCAETGGVELANEMLKLIELHDASNIAAVIVEPISG
SAGCIVPPTGYLQRLREICDQHDILLIFDEVITGFGRLGTWTAAEYFGVTPDILNFAKQVTNGAIPLGGVVASHEIYSAF
MQQDLPEHAIEFTHGYTYSAHPVACAAALAALEILEKKNLLAQSAALAPSFEKMLHGLKSAPHILDIRNCGLIGALQLAP
RDGDATIRGFELGMKLWKEGFYVRFGGDTLQFGPMFNSTEADIDRLMNAVGDALYQVN
>Mature_458_residues
MFDTDKFSDSEHTLDAVQTNNNMHINYQAHWMPFSANRNFAKDPRMIVGAKGSYLIDDSGREIFDSLSGLWTCGAGHTLP
EIQQAVSTQLGQLDYSPAFQFGHPLSFKLADKIVQHMPEKLQHVFFTNSGSESADTSIKMARAYWRIKGKPSKTKLIGRA
RGYHGVNVAGTSLGGIGGNRKMFGQLMDVDHLPHTLQPDLTFTKGCAETGGVELANEMLKLIELHDASNIAAVIVEPISG
SAGCIVPPTGYLQRLREICDQHDILLIFDEVITGFGRLGTWTAAEYFGVTPDILNFAKQVTNGAIPLGGVVASHEIYSAF
MQQDLPEHAIEFTHGYTYSAHPVACAAALAALEILEKKNLLAQSAALAPSFEKMLHGLKSAPHILDIRNCGLIGALQLAP
RDGDATIRGFELGMKLWKEGFYVRFGGDTLQFGPMFNSTEADIDRLMNAVGDALYQVN

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=401, Percent_Identity=28.6783042394015, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI37574042, Length=440, Percent_Identity=28.6363636363636, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI284507298, Length=312, Percent_Identity=30.1282051282051, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI226442705, Length=441, Percent_Identity=27.891156462585, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI13994255, Length=382, Percent_Identity=26.4397905759162, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI226442709, Length=404, Percent_Identity=28.4653465346535, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI24119277, Length=371, Percent_Identity=26.6846361185984, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI145693181, Length=312, Percent_Identity=34.9358974358974, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789759, Length=416, Percent_Identity=31.25, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786991, Length=445, Percent_Identity=28.5393258426966, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788044, Length=408, Percent_Identity=28.921568627451, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789016, Length=359, Percent_Identity=30.6406685236769, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1787560, Length=420, Percent_Identity=29.7619047619048, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786349, Length=324, Percent_Identity=27.7777777777778, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32564660, Length=456, Percent_Identity=28.7280701754386, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25144271, Length=403, Percent_Identity=26.0545905707196, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71992977, Length=386, Percent_Identity=27.979274611399, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25144274, Length=209, Percent_Identity=31.5789473684211, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323470, Length=453, Percent_Identity=26.2693156732892, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6324432, Length=423, Percent_Identity=25.7683215130024, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6324386, Length=383, Percent_Identity=27.154046997389, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574759, Length=450, Percent_Identity=28, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21357415, Length=407, Percent_Identity=25.5528255528256, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21356575, Length=382, Percent_Identity=27.4869109947644, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI161085790, Length=442, Percent_Identity=27.1493212669683, Blast_Score=128, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 50018; Mature: 50018

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTDKFSDSEHTLDAVQTNNNMHINYQAHWMPFSANRNFAKDPRMIVGAKGSYLIDDSG
CCCCCCCCCCCHHHHHEECCCCEEEEEEEEEEEECCCCCCCCCCCEEEECCCCEEECCCC
REIFDSLSGLWTCGAGHTLPEIQQAVSTQLGQLDYSPAFQFGHPLSFKLADKIVQHMPEK
HHHHHHHHCEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHH
LQHVFFTNSGSESADTSIKMARAYWRIKGKPSKTKLIGRARGYHGVNVAGTSLGGIGGNR
HHHEEEECCCCCCHHHHHHEEHHHEEECCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCH
KMFGQLMDVDHLPHTLQPDLTFTKGCAETGGVELANEMLKLIELHDASNIAAVIVEPISG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCC
SAGCIVPPTGYLQRLREICDQHDILLIFDEVITGFGRLGTWTAAEYFGVTPDILNFAKQV
CCCEEECCHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHH
TNGAIPLGGVVASHEIYSAFMQQDLPEHAIEFTHGYTYSAHPVACAAALAALEILEKKNL
HCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
LAQSAALAPSFEKMLHGLKSAPHILDIRNCGLIGALQLAPRDGDATIRGFELGMKLWKEG
HHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCEEHHHHHHHHHHHCC
FYVRFGGDTLQFGPMFNSTEADIDRLMNAVGDALYQVN
CEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFDTDKFSDSEHTLDAVQTNNNMHINYQAHWMPFSANRNFAKDPRMIVGAKGSYLIDDSG
CCCCCCCCCCCHHHHHEECCCCEEEEEEEEEEEECCCCCCCCCCCEEEECCCCEEECCCC
REIFDSLSGLWTCGAGHTLPEIQQAVSTQLGQLDYSPAFQFGHPLSFKLADKIVQHMPEK
HHHHHHHHCEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHH
LQHVFFTNSGSESADTSIKMARAYWRIKGKPSKTKLIGRARGYHGVNVAGTSLGGIGGNR
HHHEEEECCCCCCHHHHHHEEHHHEEECCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCH
KMFGQLMDVDHLPHTLQPDLTFTKGCAETGGVELANEMLKLIELHDASNIAAVIVEPISG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCC
SAGCIVPPTGYLQRLREICDQHDILLIFDEVITGFGRLGTWTAAEYFGVTPDILNFAKQV
CCCEEECCHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHH
TNGAIPLGGVVASHEIYSAFMQQDLPEHAIEFTHGYTYSAHPVACAAALAALEILEKKNL
HCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
LAQSAALAPSFEKMLHGLKSAPHILDIRNCGLIGALQLAPRDGDATIRGFELGMKLWKEG
HHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCEEHHHHHHHHHHHCC
FYVRFGGDTLQFGPMFNSTEADIDRLMNAVGDALYQVN
CEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]