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The map label for this gene is uxuR [H]

Identifier: 213158619

GI number: 213158619

Start: 2665355

End: 2666053

Strand: Reverse

Name: uxuR [H]

Synonym: AB57_2573

Alternate gene names: 213158619

Gene position: 2666053-2665355 (Counterclockwise)

Preceding gene: 213158621

Following gene: 213158618

Centisome position: 65.82

GC content: 36.91

Gene sequence:

>699_bases
ATGATTGAGCAAATTCAAAAAAGATCACTGGTCGATGAAGTGATTCATGTCATACGCCAGAATATTAAAAATGATATTTG
GAAAGTAGATGAGAAAATTCCCACTGAACCTGAGCTTGTTCAAGGTTTGGGTGTGGGGCGAAACACCATTCGTGAAGCAA
TTAAAATTTTAGAATATTTAGGTGTTTTAGAAGTCAAACAGGGGCTGGGTACTTTTGTACGTACGAAGAATGACTTTTCG
ATTGTGATTAATTCAATTCATCATTCTGATTTATATGAACACGTAGAAGTACGATGTTTATTAGAAATCGAAATTGCTAA
ATTAGCCGCTAGACATAGCACGCCTGAAGATATGCGCGATGTTATAGCGTGTTTAGAACATAGAGCAGCAACAAATCAAC
AAGATGTTGCTAACTTCATGTTAAGTGATAAGAAACTACATTTGGCAATTGCCAAGGCGACTCATAATAAAGCTTTACAG
GCAACTTATGAGTATTTCTTAAACTCAAGCTATCAATACACCTTAGAGCTAGTGACTAATAAAAATTTACCTGACCCAAA
CCAGCAAATACATAGTGAACTTGTTCAAGCTATTCAACACAAGTCTGAGTCAGAAGCCATGCGAGTTGCGGAGTCTATGT
TGGCGCCCATATTACGTTCGCTAGATTCAATTAAAGCTGACTTTGTCCAAAACCACTAA

Upstream 100 bases:

>100_bases
CCATGAGCTCAACCTTTAAAAATGCATGAAAGAGAAATTGAACAATTAAACATAGGATGATAGTATCACCGTATGTTTAA
GCTTACTAGTACCAATTTTA

Downstream 100 bases:

>100_bases
ATAGCTAGATCAAGTACTATGAGTTTTATGATTGTTTCGAACAACTTTGCTGTTCCTTACTATTTAAATGTGAGGAAAGA
AAAGGGAATGACGGCTTATT

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MIEQIQKRSLVDEVIHVIRQNIKNDIWKVDEKIPTEPELVQGLGVGRNTIREAIKILEYLGVLEVKQGLGTFVRTKNDFS
IVINSIHHSDLYEHVEVRCLLEIEIAKLAARHSTPEDMRDVIACLEHRAATNQQDVANFMLSDKKLHLAIAKATHNKALQ
ATYEYFLNSSYQYTLELVTNKNLPDPNQQIHSELVQAIQHKSESEAMRVAESMLAPILRSLDSIKADFVQNH

Sequences:

>Translated_232_residues
MIEQIQKRSLVDEVIHVIRQNIKNDIWKVDEKIPTEPELVQGLGVGRNTIREAIKILEYLGVLEVKQGLGTFVRTKNDFS
IVINSIHHSDLYEHVEVRCLLEIEIAKLAARHSTPEDMRDVIACLEHRAATNQQDVANFMLSDKKLHLAIAKATHNKALQ
ATYEYFLNSSYQYTLELVTNKNLPDPNQQIHSELVQAIQHKSESEAMRVAESMLAPILRSLDSIKADFVQNH
>Mature_232_residues
MIEQIQKRSLVDEVIHVIRQNIKNDIWKVDEKIPTEPELVQGLGVGRNTIREAIKILEYLGVLEVKQGLGTFVRTKNDFS
IVINSIHHSDLYEHVEVRCLLEIEIAKLAARHSTPEDMRDVIACLEHRAATNQQDVANFMLSDKKLHLAIAKATHNKALQ
ATYEYFLNSSYQYTLELVTNKNLPDPNQQIHSELVQAIQHKSESEAMRVAESMLAPILRSLDSIKADFVQNH

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789353, Length=233, Percent_Identity=27.4678111587983, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790032, Length=172, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1790780, Length=168, Percent_Identity=33.9285714285714, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994955, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26483; Mature: 26483

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEQIQKRSLVDEVIHVIRQNIKNDIWKVDEKIPTEPELVQGLGVGRNTIREAIKILEYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
GVLEVKQGLGTFVRTKNDFSIVINSIHHSDLYEHVEVRCLLEIEIAKLAARHSTPEDMRD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VIACLEHRAATNQQDVANFMLSDKKLHLAIAKATHNKALQATYEYFLNSSYQYTLELVTN
HHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
KNLPDPNQQIHSELVQAIQHKSESEAMRVAESMLAPILRSLDSIKADFVQNH
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIEQIQKRSLVDEVIHVIRQNIKNDIWKVDEKIPTEPELVQGLGVGRNTIREAIKILEYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
GVLEVKQGLGTFVRTKNDFSIVINSIHHSDLYEHVEVRCLLEIEIAKLAARHSTPEDMRD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VIACLEHRAATNQQDVANFMLSDKKLHLAIAKATHNKALQATYEYFLNSSYQYTLELVTN
HHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
KNLPDPNQQIHSELVQAIQHKSESEAMRVAESMLAPILRSLDSIKADFVQNH
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]