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The map label for this gene is qseC [H]

Identifier: 213158588

GI number: 213158588

Start: 2636209

End: 2637537

Strand: Reverse

Name: qseC [H]

Synonym: AB57_2542

Alternate gene names: 213158588

Gene position: 2637537-2636209 (Counterclockwise)

Preceding gene: 213158590

Following gene: 213158584

Centisome position: 65.12

GC content: 39.28

Gene sequence:

>1329_bases
ATGATAAGAACTCGACATGATGGCAAAACGAGTCATCCATTAGCCCAAATGTTCAATCGATATTACTGGTTGCAAATTGG
TCTGATTGCATTATCGATCGTGGTCGGGTTGGCTTGTAGTGCTTGGGTGATTAAGGGTTCTTTACTTAAAACCGCTTTAG
AACAGGAAATGGAGCATTACTGGTTACGTATAGAACGTAACCCAAATGCTGATTTACCAGATACTAAAAATTTATATGGA
TATCGGTGGAATACACAGGTCGCGCCTCAACCTTTTCGGGGCATGCATTTAGAAAGTGGCGTGCACCGAGTATTCGTTGA
TGGTAAAGAACGAATGACGGTCTATGGTGAGCGTAATGGTCAACATGTTCTATTGGTATTTGGCGAAAGCAATGTTAATA
AGCTGATCTGGTTATTTGGTCTTGCTCCACTCATGTTCAGCTTATCTGTTCTATATAGTTTTTTGTGGTGGTCAAACCGA
AGAGCAAGACGCTATTTTTCCCCAATTACGCGTTTAGCAAATGCTTTAGAAAATATTGATTGGGCACATCAAGACACTCA
GGCATCTCCTTTTAGAGATATTAATACCAATGGCAATATGGAAGCCGAATATCTCAAACAAGCTTTAGAAAAATATCATC
AGGTTTTAAGTGATTTTATTCGACGTGAAAGAGAATTTACTGGAGATGTGAGCCATGAGTTACGCACTCCACTCACCATT
TTGAAAGGTAATGTACAACTGTGTCAGGCGAAATTCGGAGACGATAAATCTTTAGTCCGTCTTCATAACACAATTGAAGA
TATGCAGTTGCTCGTCGATACCTTACTGGCGATTGCTCGGAATACGGTAAAAAGCTTGCCATCTGAGAAAAATTTATTAT
CCAAAACGGTAAAAGATCTTGTTGAAAGTTTAGAAGCGGTGAGCGCGGGTAAAGGGATACAGATTAATATTCAACCTGAT
GTTTCTGAACAGCCGCGTTGGTTATATCCTTCTATGACTCAAATGGTTTTAGGTAATATTTTACGTAATGCGCTGAACTA
TTCTCAAGGCTCACAAATCGACATTATTCAACAAAAAAACAGCCTGATTATTGCTGATAATGGAATTGGAATTTCTTTAC
CTAACGATGTGAAAGTGCAAGAGCTCAGCGATTCGCAACTTTCCTTAAAGGCTAAAGGTCATGGCATTGGTTTGCAATTG
GTACAAAAGCTTTGCAAACAACTAGGATGGAGAGTGGAGCTGTTTGATCGACAATATTATTTAACCACTCATCCTGAACT
CGATTTGGAGCCAACCACAGGCTTAATTGTTGTGGTCTATTTAAGTTAA

Upstream 100 bases:

>100_bases
AGCTATTCGGTTTTGAGCAAGGACAAGAATGGGTCATTGGTCACTTTTTATTTAAAAAGCGATCATAGTAATTTCTATAG
CCTATCCCGACGATAAAGAT

Downstream 100 bases:

>100_bases
GTCGCGGAATCTTCCAAAGCAATTTTTAAACCAACACCTGCCACTGTATGTAATAGCTTTGGGTCAAAAGGTTTATCAAC
CATTTTTCTTAAGTTATAGA

Product: two-component system sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MIRTRHDGKTSHPLAQMFNRYYWLQIGLIALSIVVGLACSAWVIKGSLLKTALEQEMEHYWLRIERNPNADLPDTKNLYG
YRWNTQVAPQPFRGMHLESGVHRVFVDGKERMTVYGERNGQHVLLVFGESNVNKLIWLFGLAPLMFSLSVLYSFLWWSNR
RARRYFSPITRLANALENIDWAHQDTQASPFRDINTNGNMEAEYLKQALEKYHQVLSDFIRREREFTGDVSHELRTPLTI
LKGNVQLCQAKFGDDKSLVRLHNTIEDMQLLVDTLLAIARNTVKSLPSEKNLLSKTVKDLVESLEAVSAGKGIQINIQPD
VSEQPRWLYPSMTQMVLGNILRNALNYSQGSQIDIIQQKNSLIIADNGIGISLPNDVKVQELSDSQLSLKAKGHGIGLQL
VQKLCKQLGWRVELFDRQYYLTTHPELDLEPTTGLIVVVYLS

Sequences:

>Translated_442_residues
MIRTRHDGKTSHPLAQMFNRYYWLQIGLIALSIVVGLACSAWVIKGSLLKTALEQEMEHYWLRIERNPNADLPDTKNLYG
YRWNTQVAPQPFRGMHLESGVHRVFVDGKERMTVYGERNGQHVLLVFGESNVNKLIWLFGLAPLMFSLSVLYSFLWWSNR
RARRYFSPITRLANALENIDWAHQDTQASPFRDINTNGNMEAEYLKQALEKYHQVLSDFIRREREFTGDVSHELRTPLTI
LKGNVQLCQAKFGDDKSLVRLHNTIEDMQLLVDTLLAIARNTVKSLPSEKNLLSKTVKDLVESLEAVSAGKGIQINIQPD
VSEQPRWLYPSMTQMVLGNILRNALNYSQGSQIDIIQQKNSLIIADNGIGISLPNDVKVQELSDSQLSLKAKGHGIGLQL
VQKLCKQLGWRVELFDRQYYLTTHPELDLEPTTGLIVVVYLS
>Mature_442_residues
MIRTRHDGKTSHPLAQMFNRYYWLQIGLIALSIVVGLACSAWVIKGSLLKTALEQEMEHYWLRIERNPNADLPDTKNLYG
YRWNTQVAPQPFRGMHLESGVHRVFVDGKERMTVYGERNGQHVLLVFGESNVNKLIWLFGLAPLMFSLSVLYSFLWWSNR
RARRYFSPITRLANALENIDWAHQDTQASPFRDINTNGNMEAEYLKQALEKYHQVLSDFIRREREFTGDVSHELRTPLTI
LKGNVQLCQAKFGDDKSLVRLHNTIEDMQLLVDTLLAIARNTVKSLPSEKNLLSKTVKDLVESLEAVSAGKGIQINIQPD
VSEQPRWLYPSMTQMVLGNILRNALNYSQGSQIDIIQQKNSLIIADNGIGISLPNDVKVQELSDSQLSLKAKGHGIGLQL
VQKLCKQLGWRVELFDRQYYLTTHPELDLEPTTGLIVVVYLS

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=326, Percent_Identity=29.1411042944785, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790346, Length=265, Percent_Identity=26.7924528301887, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789149, Length=348, Percent_Identity=24.4252873563218, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50501; Mature: 50501

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTRHDGKTSHPLAQMFNRYYWLQIGLIALSIVVGLACSAWVIKGSLLKTALEQEMEHY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
WLRIERNPNADLPDTKNLYGYRWNTQVAPQPFRGMHLESGVHRVFVDGKERMTVYGERNG
EEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHCCCEEEEECCCCEEEEEECCCC
QHVLLVFGESNVNKLIWLFGLAPLMFSLSVLYSFLWWSNRRARRYFSPITRLANALENID
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
WAHQDTQASPFRDINTNGNMEAEYLKQALEKYHQVLSDFIRREREFTGDVSHELRTPLTI
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHE
LKGNVQLCQAKFGDDKSLVRLHNTIEDMQLLVDTLLAIARNTVKSLPSEKNLLSKTVKDL
EECCHHEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VESLEAVSAGKGIQINIQPDVSEQPRWLYPSMTQMVLGNILRNALNYSQGSQIDIIQQKN
HHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
SLIIADNGIGISLPNDVKVQELSDSQLSLKAKGHGIGLQLVQKLCKQLGWRVELFDRQYY
CEEEEECCEEEECCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCEEE
LTTHPELDLEPTTGLIVVVYLS
EEECCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MIRTRHDGKTSHPLAQMFNRYYWLQIGLIALSIVVGLACSAWVIKGSLLKTALEQEMEHY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
WLRIERNPNADLPDTKNLYGYRWNTQVAPQPFRGMHLESGVHRVFVDGKERMTVYGERNG
EEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHCCCEEEEECCCCEEEEEECCCC
QHVLLVFGESNVNKLIWLFGLAPLMFSLSVLYSFLWWSNRRARRYFSPITRLANALENID
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
WAHQDTQASPFRDINTNGNMEAEYLKQALEKYHQVLSDFIRREREFTGDVSHELRTPLTI
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHE
LKGNVQLCQAKFGDDKSLVRLHNTIEDMQLLVDTLLAIARNTVKSLPSEKNLLSKTVKDL
EECCHHEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VESLEAVSAGKGIQINIQPDVSEQPRWLYPSMTQMVLGNILRNALNYSQGSQIDIIQQKN
HHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
SLIIADNGIGISLPNDVKVQELSDSQLSLKAKGHGIGLQLVQKLCKQLGWRVELFDRQYY
CEEEEECCEEEECCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCEEE
LTTHPELDLEPTTGLIVVVYLS
EEECCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]