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The map label for this gene is kdpE [H]

Identifier: 213158519

GI number: 213158519

Start: 2562368

End: 2563084

Strand: Reverse

Name: kdpE [H]

Synonym: AB57_2470

Alternate gene names: 213158519

Gene position: 2563084-2562368 (Counterclockwise)

Preceding gene: 213158520

Following gene: 213158517

Centisome position: 63.28

GC content: 41.0

Gene sequence:

>717_bases
ATGATAAGTTCAGAAACATCACCTGTAGAAACACGTATTGTGATTATTGATGATGAGCCTCAAATCCGTAAATTTTTAGA
CATTGCTTTAAGAACTCAAAAATACAAAACCACGCTCTGCGAAACGGGTTACAAAGGCCTAGAGACTTTGGCAACCCAAG
GAGCTGATTTGGTGATTCTAGACTTAGGCTTACCCGATTTAGATGGAAGAGAAGTGCTTCAAGAATTACGTAGCTGGTCG
AATGTTCCCGTTATTGTGTTATCTGTACGTGCTGATGAATATGAAAAAGTTGCTTTGCTCGATGCTGGCGCAAATGATTA
CATGACCAAGCCGTTTAGTGTGCAAGAGCTTTTGGCACGCATACGTGTCATTCTAAGAAATCAACCGATTCAGCAAGAAG
CTCATGTGTATGACGATGGCTATCTTAAAGTCGATATTACGCAACGTTTAGTTTGGGTCGAGCAACAGCCAATTACTTTA
ACTCGAAAAGAGTTTCAACTTTTGACGCTCTTAATGCGCTATCAAGGGCAGCTTTTAACACAGCCACAGCTCTTAAAAGA
ACTATGGGGACCCACCCATCAGGAAGATACGCACTATTTACGTATTTTAGTGGGCAAGTTACGTAGTAAACTGGGGGATA
ACGCGATTCAGCCACGCTATATTGCTACTGAACCTGGTGTAGGATTACGTTTTTTAGCTAAGCAGAAAAATCATTAA

Upstream 100 bases:

>100_bases
ATATGGGTACAATAGAAGCATTTTCAGGGCGCCAAAATAAAGGTACTTTAATTCAAATCAAATTACCCCTTCATCCAGTA
AAAGAATAAGTTGTAAATTC

Downstream 100 bases:

>100_bases
TTAGATGTAAAAAAACCTTAGGGTATTTCTCCCTAAGGGTTTGCAAAGTGGTTTATAGTTTTTTGCTTTTTTTATTCAAA
TATTCCAATGTTGTTCTGCT

Product: two-component system regulatory protein KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MISSETSPVETRIVIIDDEPQIRKFLDIALRTQKYKTTLCETGYKGLETLATQGADLVILDLGLPDLDGREVLQELRSWS
NVPVIVLSVRADEYEKVALLDAGANDYMTKPFSVQELLARIRVILRNQPIQQEAHVYDDGYLKVDITQRLVWVEQQPITL
TRKEFQLLTLLMRYQGQLLTQPQLLKELWGPTHQEDTHYLRILVGKLRSKLGDNAIQPRYIATEPGVGLRFLAKQKNH

Sequences:

>Translated_238_residues
MISSETSPVETRIVIIDDEPQIRKFLDIALRTQKYKTTLCETGYKGLETLATQGADLVILDLGLPDLDGREVLQELRSWS
NVPVIVLSVRADEYEKVALLDAGANDYMTKPFSVQELLARIRVILRNQPIQQEAHVYDDGYLKVDITQRLVWVEQQPITL
TRKEFQLLTLLMRYQGQLLTQPQLLKELWGPTHQEDTHYLRILVGKLRSKLGDNAIQPRYIATEPGVGLRFLAKQKNH
>Mature_238_residues
MISSETSPVETRIVIIDDEPQIRKFLDIALRTQKYKTTLCETGYKGLETLATQGADLVILDLGLPDLDGREVLQELRSWS
NVPVIVLSVRADEYEKVALLDAGANDYMTKPFSVQELLARIRVILRNQPIQQEAHVYDDGYLKVDITQRLVWVEQQPITL
TRKEFQLLTLLMRYQGQLLTQPQLLKELWGPTHQEDTHYLRILVGKLRSKLGDNAIQPRYIATEPGVGLRFLAKQKNH

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=45.8149779735683, Blast_Score=194, Evalue=4e-51,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=34.3891402714932, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=35.1111111111111, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=31.0043668122271, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=32.5991189427313, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=32.5688073394495, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=29.5154185022026, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=28.8888888888889, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=30.9417040358744, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=28.9473684210526, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=30.316742081448, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=27.0742358078603, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=28.8888888888889, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=27.7056277056277, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1788550, Length=124, Percent_Identity=33.8709677419355, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790299, Length=130, Percent_Identity=31.5384615384615, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=129, Percent_Identity=27.906976744186, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27290; Mature: 27290

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSETSPVETRIVIIDDEPQIRKFLDIALRTQKYKTTLCETGYKGLETLATQGADLVIL
CCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEE
DLGLPDLDGREVLQELRSWSNVPVIVLSVRADEYEKVALLDAGANDYMTKPFSVQELLAR
ECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCHHHHHHH
IRVILRNQPIQQEAHVYDDGYLKVDITQRLVWVEQQPITLTRKEFQLLTLLMRYQGQLLT
HHHHHCCCCCCCCCEEECCCEEEEEEEHEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCC
QPQLLKELWGPTHQEDTHYLRILVGKLRSKLGDNAIQPRYIATEPGVGLRFLAKQKNH
CHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEECCCCCC
>Mature Secondary Structure
MISSETSPVETRIVIIDDEPQIRKFLDIALRTQKYKTTLCETGYKGLETLATQGADLVIL
CCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEE
DLGLPDLDGREVLQELRSWSNVPVIVLSVRADEYEKVALLDAGANDYMTKPFSVQELLAR
ECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCHHHHHHH
IRVILRNQPIQQEAHVYDDGYLKVDITQRLVWVEQQPITLTRKEFQLLTLLMRYQGQLLT
HHHHHCCCCCCCCCEEECCCEEEEEEEHEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCC
QPQLLKELWGPTHQEDTHYLRILVGKLRSKLGDNAIQPRYIATEPGVGLRFLAKQKNH
CHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]