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The map label for this gene is yqcB [C]

Identifier: 213158499

GI number: 213158499

Start: 2537669

End: 2538577

Strand: Direct

Name: yqcB [C]

Synonym: AB57_2450

Alternate gene names: 213158499

Gene position: 2537669-2538577 (Clockwise)

Preceding gene: 213158493

Following gene: 213158500

Centisome position: 62.65

GC content: 37.07

Gene sequence:

>909_bases
ATGTCTAGCCCGATTGAATTTTTCCCACCTATGATTGATGGCGTAAGCGCAAGCCAAGTCTATCTTCCTCCACAAACGAC
AGCACAAACCATCTATCAATTTCTTTGCGAAAATTTTCCTCATATAAAAGCAACAGAGTGGCAGCAGCGTTTTCAAGATG
GGCTTATTTACGCGGCAAATGGCGAAAAATTAACATTAAACAGCTCTTATATAGCAAACACACATATTTTTTATTACCGA
TTCCTTGCTAACGAAGTACATGTTCCCTTTGAGCATCAGATTTTATTTGAAAATGATGATTTGCTTGTTGTAGATAAACC
CCATTTTTTAACGATTAGCCCAACAGGGCAATATGTACAAGAAACATTATTAGTCCGACTAAAAAAGCAAACTGGCAATG
AGTTTTTAACCCCGATCCACCGATTAGATCGTGAAACTGCCGGTGTCGTTTTATTTTGCAAACGACCGCAGTCACGTGGA
ATTTACCAACAGTTATTTGCAGATCGTCAAGTCAATAAGATTTACCATGCAATCGCTCCATATAAAGCTGAATTAAAATT
TCCTCAGAGTTTAAAACTGTATTTAGATAAAGGTACACCCTTTTATACAATGCAGGTGATTGCACATACAAAAACCAATA
CCGAAACTAAAATTGAGCTGATTGAACATAATCACTCATGGGCTAAATATTGTTTAACGCCAACCACCGGAAAACAGCAT
CAACTCCGCGTCCATTTAAATCATTTGGGAATTCCGATTAAAAATGATCCGTTTTATCCAATAGTTCAACATAAAGCCGA
TGATGATTTTTCTCAGCCCTTACAGCTTCTAGCTAAGCAAATTTCTTTTATAGACCCGCTAACAAAACAGGAAATGGTTT
TCAATTCACAGCTTGAATTGACACTGTAA

Upstream 100 bases:

>100_bases
AAAATAATCGATATGATACCATTGCCCTGCTTTAAAGCCTACTTAAGTGCTTAACGTTGGCTTTTTTTACATCACATTTA
TTAAATATTGACACACTTTT

Downstream 100 bases:

>100_bases
TCGCATCGTAATGACAAAAAGATTATTTTTTATGCTGAAAGACATTGAAATTACATTCCGATGGTTTAAAATAAATCCCT
AAAAATTAAAAATCATTTGG

Product: RNA pseudouridine synthase family protein

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSSPIEFFPPMIDGVSASQVYLPPQTTAQTIYQFLCENFPHIKATEWQQRFQDGLIYAANGEKLTLNSSYIANTHIFYYR
FLANEVHVPFEHQILFENDDLLVVDKPHFLTISPTGQYVQETLLVRLKKQTGNEFLTPIHRLDRETAGVVLFCKRPQSRG
IYQQLFADRQVNKIYHAIAPYKAELKFPQSLKLYLDKGTPFYTMQVIAHTKTNTETKIELIEHNHSWAKYCLTPTTGKQH
QLRVHLNHLGIPIKNDPFYPIVQHKADDDFSQPLQLLAKQISFIDPLTKQEMVFNSQLELTL

Sequences:

>Translated_302_residues
MSSPIEFFPPMIDGVSASQVYLPPQTTAQTIYQFLCENFPHIKATEWQQRFQDGLIYAANGEKLTLNSSYIANTHIFYYR
FLANEVHVPFEHQILFENDDLLVVDKPHFLTISPTGQYVQETLLVRLKKQTGNEFLTPIHRLDRETAGVVLFCKRPQSRG
IYQQLFADRQVNKIYHAIAPYKAELKFPQSLKLYLDKGTPFYTMQVIAHTKTNTETKIELIEHNHSWAKYCLTPTTGKQH
QLRVHLNHLGIPIKNDPFYPIVQHKADDDFSQPLQLLAKQISFIDPLTKQEMVFNSQLELTL
>Mature_301_residues
SSPIEFFPPMIDGVSASQVYLPPQTTAQTIYQFLCENFPHIKATEWQQRFQDGLIYAANGEKLTLNSSYIANTHIFYYRF
LANEVHVPFEHQILFENDDLLVVDKPHFLTISPTGQYVQETLLVRLKKQTGNEFLTPIHRLDRETAGVVLFCKRPQSRGI
YQQLFADRQVNKIYHAIAPYKAELKFPQSLKLYLDKGTPFYTMQVIAHTKTNTETKIELIEHNHSWAKYCLTPTTGKQHQ
LRVHLNHLGIPIKNDPFYPIVQHKADDDFSQPLQLLAKQISFIDPLTKQEMVFNSQLELTL

Specific function: Unknown

COG id: COG0564

COG function: function code J; Pseudouridylate synthases, 23S RNA-specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI23308689, Length=215, Percent_Identity=32.5581395348837, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1789155, Length=227, Percent_Identity=27.7533039647577, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17534965, Length=213, Percent_Identity=27.2300469483568, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324506, Length=175, Percent_Identity=31.4285714285714, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320168, Length=175, Percent_Identity=33.1428571428571, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321608, Length=192, Percent_Identity=33.8541666666667, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24583449, Length=244, Percent_Identity=29.9180327868852, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24583447, Length=244, Percent_Identity=29.9180327868852, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24583445, Length=244, Percent_Identity=29.9180327868852, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI19921090, Length=207, Percent_Identity=32.8502415458937, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006225
- InterPro:   IPR006224
- InterPro:   IPR006145
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 35021; Mature: 34889

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS01129 PSI_RLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPIEFFPPMIDGVSASQVYLPPQTTAQTIYQFLCENFPHIKATEWQQRFQDGLIYAAN
CCCCCCCCCHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEC
GEKLTLNSSYIANTHIFYYRFLANEVHVPFEHQILFENDDLLVVDKPHFLTISPTGQYVQ
CCEEEECCCEEECCEEEEEEEECCCCCCCCCEEEEEECCCEEEEECCCEEEECCCHHHHH
ETLLVRLKKQTGNEFLTPIHRLDRETAGVVLFCKRPQSRGIYQQLFADRQVNKIYHAIAP
HHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHCHHHHHHHHHHCC
YKAELKFPQSLKLYLDKGTPFYTMQVIAHTKTNTETKIELIEHNHSWAKYCLTPTTGKQH
CEEECCCCCEEEEEEECCCCEEEEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCE
QLRVHLNHLGIPIKNDPFYPIVQHKADDDFSQPLQLLAKQISFIDPLTKQEMVFNSQLEL
EEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEE
TL
EC
>Mature Secondary Structure 
SSPIEFFPPMIDGVSASQVYLPPQTTAQTIYQFLCENFPHIKATEWQQRFQDGLIYAAN
CCCCCCCCHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEC
GEKLTLNSSYIANTHIFYYRFLANEVHVPFEHQILFENDDLLVVDKPHFLTISPTGQYVQ
CCEEEECCCEEECCEEEEEEEECCCCCCCCCEEEEEECCCEEEEECCCEEEECCCHHHHH
ETLLVRLKKQTGNEFLTPIHRLDRETAGVVLFCKRPQSRGIYQQLFADRQVNKIYHAIAP
HHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHCHHHHHHHHHHCC
YKAELKFPQSLKLYLDKGTPFYTMQVIAHTKTNTETKIELIEHNHSWAKYCLTPTTGKQH
CEEECCCCCEEEEEEECCCCEEEEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCE
QLRVHLNHLGIPIKNDPFYPIVQHKADDDFSQPLQLLAKQISFIDPLTKQEMVFNSQLEL
EEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEE
TL
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]