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The map label for this gene is glnS [H]

Identifier: 213158490

GI number: 213158490

Start: 2528391

End: 2530118

Strand: Reverse

Name: glnS [H]

Synonym: AB57_2440

Alternate gene names: 213158490

Gene position: 2530118-2528391 (Counterclockwise)

Preceding gene: 213158494

Following gene: 213158482

Centisome position: 62.46

GC content: 41.61

Gene sequence:

>1728_bases
ATGAAGCCTAATGATGTTGTCTCGAACCTGCCAAACAACCCGACACCGAATACTCATGCCTCTGTCGATTCTGCGCAGCA
AGAACAACAGGCTGGATTAGATTTTGTTCGCCAAGTCATTACCGATGATTTAGCTGCCGGACGTGCCAAACAAATCGTAA
CGCGTTTCCCGCCAGAACCAAATGGTTATTTACATATTGGTCACGTAAAAGCAATTTGCCTCAACTTTGGCGTTGCTGAA
GAGTTTAATGGTCTTTGTAATTTACGTTTTGACGATACTAACCCGGATGCGGAAGAACAAGAGTATGTTGATGGTATCGC
CAATGATGTGAAATGGCTTGGATTTAGCTGGAATGGCGAACCACGTTATGCTTCCGGTTATTTTGATCAGCTATATGCTT
GGGCAATTCAGTTGATTGAACAAGGCGATGCATATGTTGATTTGCAGTCTCCAGAAGAAATCAAATTAAATCGTGGTAGC
TTTGTTGAGCCAGGTAAAAATTCGCCATATCGTGATGCTTCTGTTGAAGAAAACCTTGCTCGTTTTGAAAAAATGCGCAA
TGGTGAACTTAAAGAAGGTGAAGCTGTTTTACGTGCCAAAATTGATATGGCAAGCCCGAATGTACATATGCGTGACCCAA
TTTTGTATCGTGTTTTACATTCAGAGCATCACCAAACAGGTGATAAGTGGAAAATCTACCCAATGTATGACTATGCTCAT
CCATTGTCTGATGCGATCGAAGGAATCACACATTCACTTTGTACATTAGAGTTCCAAGACCACCGTCCGTTTTATGACTG
GATTGTTGAAAAAGTTAAGTCTAAAGCTGTGCCGCACCAATATGAATCTTCTCGTTTAAACGTAGATTACACCATTACGT
CTAAACGTAAATTACGTAAATTGGTTGAAGGCGGTTATGTGAATGGATGGGATGATCCTCGTATGCCAACGGTTGTCGGT
ATGCGTCGCCGTGGTTTCACACCAGAAGGCCTACGTGATTTCTGTAAACGTGTAGGTGTGTCTAAAACTGACGGTATTGT
GGATGTCGCAATGCTTGAGTTCTGTATTCGTCAATCTTTAGAGAATACGGCAGCGCGCGGTATGGCAGTGTTAAATCCAT
TAAAAGTAACACTTACGAACTTACCGGAAGATTTAGACCTTACCCATGCTCGTCATCCTAATGTCGATATGGGTGAGCGC
GTTATTCCATTAACTAAAGAAATCTATATTGACCGTAAAGATTTCGAAGAAGTACCGCCAAAAGGCTTTAAACGTTTAAT
TCCTGATGGTGAAGTTCGTCTACGCCATGCATATGTGATTAAGTGTGATGAAGTCATTAAAGATGCAAACGGTGAAGTCA
TTGAGCTGAAGTGTTCAATCGATCCGGATACTTTAGGTAAAAATCCTGAAGGCCGCAAAGTAAAAGGCGTAATTCACTGG
GTATCTGCAACTAAAGGTATTCCTGCTGAAGTACGTATTTATGATCGACTGTTTACAGAAGCTGACCCTGAAACTGGTGA
TGATTTCTTAGCAAACTTAAATCCAGATTCTTTGAAAGTGGTTCAAGCTGTAATCGAACCTGCTTTAGCTCAAGCGAAGC
CAGAAGATCGCTTCCAGTTTGAACGCGAAGGTTATTTCGTTGCTGATCAATACGATCATACTCCTGAGAAGCCTGTGTTT
AACCGTGTTCTTGACTTAAAAGACAGCTTCAAGCCTGAGAAAAAGTAA

Upstream 100 bases:

>100_bases
TAAACTACAAGGCAAGTAAAAAACGTTAAAATCTTTGTGAAAAATGAAGATAGCGTTTATTTTTTCGAAATTTTATCTAC
AAAGAAGTGATTGATACACT

Downstream 100 bases:

>100_bases
GAGATTGATTATCTCTTACTTTTTCGCAAGACGAATATCATGTGGTGAGTAAACAGAAGATATAAAAAAGCCCAACTGTA
AAGTTGGGCTTTTTATTCAG

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MKPNDVVSNLPNNPTPNTHASVDSAQQEQQAGLDFVRQVITDDLAAGRAKQIVTRFPPEPNGYLHIGHVKAICLNFGVAE
EFNGLCNLRFDDTNPDAEEQEYVDGIANDVKWLGFSWNGEPRYASGYFDQLYAWAIQLIEQGDAYVDLQSPEEIKLNRGS
FVEPGKNSPYRDASVEENLARFEKMRNGELKEGEAVLRAKIDMASPNVHMRDPILYRVLHSEHHQTGDKWKIYPMYDYAH
PLSDAIEGITHSLCTLEFQDHRPFYDWIVEKVKSKAVPHQYESSRLNVDYTITSKRKLRKLVEGGYVNGWDDPRMPTVVG
MRRRGFTPEGLRDFCKRVGVSKTDGIVDVAMLEFCIRQSLENTAARGMAVLNPLKVTLTNLPEDLDLTHARHPNVDMGER
VIPLTKEIYIDRKDFEEVPPKGFKRLIPDGEVRLRHAYVIKCDEVIKDANGEVIELKCSIDPDTLGKNPEGRKVKGVIHW
VSATKGIPAEVRIYDRLFTEADPETGDDFLANLNPDSLKVVQAVIEPALAQAKPEDRFQFEREGYFVADQYDHTPEKPVF
NRVLDLKDSFKPEKK

Sequences:

>Translated_575_residues
MKPNDVVSNLPNNPTPNTHASVDSAQQEQQAGLDFVRQVITDDLAAGRAKQIVTRFPPEPNGYLHIGHVKAICLNFGVAE
EFNGLCNLRFDDTNPDAEEQEYVDGIANDVKWLGFSWNGEPRYASGYFDQLYAWAIQLIEQGDAYVDLQSPEEIKLNRGS
FVEPGKNSPYRDASVEENLARFEKMRNGELKEGEAVLRAKIDMASPNVHMRDPILYRVLHSEHHQTGDKWKIYPMYDYAH
PLSDAIEGITHSLCTLEFQDHRPFYDWIVEKVKSKAVPHQYESSRLNVDYTITSKRKLRKLVEGGYVNGWDDPRMPTVVG
MRRRGFTPEGLRDFCKRVGVSKTDGIVDVAMLEFCIRQSLENTAARGMAVLNPLKVTLTNLPEDLDLTHARHPNVDMGER
VIPLTKEIYIDRKDFEEVPPKGFKRLIPDGEVRLRHAYVIKCDEVIKDANGEVIELKCSIDPDTLGKNPEGRKVKGVIHW
VSATKGIPAEVRIYDRLFTEADPETGDDFLANLNPDSLKVVQAVIEPALAQAKPEDRFQFEREGYFVADQYDHTPEKPVF
NRVLDLKDSFKPEKK
>Mature_575_residues
MKPNDVVSNLPNNPTPNTHASVDSAQQEQQAGLDFVRQVITDDLAAGRAKQIVTRFPPEPNGYLHIGHVKAICLNFGVAE
EFNGLCNLRFDDTNPDAEEQEYVDGIANDVKWLGFSWNGEPRYASGYFDQLYAWAIQLIEQGDAYVDLQSPEEIKLNRGS
FVEPGKNSPYRDASVEENLARFEKMRNGELKEGEAVLRAKIDMASPNVHMRDPILYRVLHSEHHQTGDKWKIYPMYDYAH
PLSDAIEGITHSLCTLEFQDHRPFYDWIVEKVKSKAVPHQYESSRLNVDYTITSKRKLRKLVEGGYVNGWDDPRMPTVVG
MRRRGFTPEGLRDFCKRVGVSKTDGIVDVAMLEFCIRQSLENTAARGMAVLNPLKVTLTNLPEDLDLTHARHPNVDMGER
VIPLTKEIYIDRKDFEEVPPKGFKRLIPDGEVRLRHAYVIKCDEVIKDANGEVIELKCSIDPDTLGKNPEGRKVKGVIHW
VSATKGIPAEVRIYDRLFTEADPETGDDFLANLNPDSLKVVQAVIEPALAQAKPEDRFQFEREGYFVADQYDHTPEKPVF
NRVLDLKDSFKPEKK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=529, Percent_Identity=46.8809073724008, Blast_Score=436, Evalue=1e-122,
Organism=Homo sapiens, GI62241042, Length=522, Percent_Identity=33.7164750957854, Blast_Score=269, Evalue=5e-72,
Organism=Escherichia coli, GI1786895, Length=540, Percent_Identity=57.5925925925926, Blast_Score=663, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=354, Percent_Identity=24.8587570621469, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17543332, Length=536, Percent_Identity=42.7238805970149, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17511007, Length=525, Percent_Identity=32, Blast_Score=249, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6324742, Length=563, Percent_Identity=40.4973357015986, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321192, Length=519, Percent_Identity=36.4161849710983, Blast_Score=300, Evalue=6e-82,
Organism=Drosophila melanogaster, GI17864488, Length=527, Percent_Identity=44.022770398482, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24649466, Length=518, Percent_Identity=34.3629343629344, Blast_Score=269, Evalue=3e-72,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 65363; Mature: 65363

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNDVVSNLPNNPTPNTHASVDSAQQEQQAGLDFVRQVITDDLAAGRAKQIVTRFPPEP
CCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
NGYLHIGHVKAICLNFGVAEEFNGLCNLRFDDTNPDAEEQEYVDGIANDVKWLGFSWNGE
CCEEEECHHHHHHHHCCCHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCC
PRYASGYFDQLYAWAIQLIEQGDAYVDLQSPEEIKLNRGSFVEPGKNSPYRDASVEENLA
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHH
RFEKMRNGELKEGEAVLRAKIDMASPNVHMRDPILYRVLHSEHHQTGDKWKIYPMYDYAH
HHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHC
PLSDAIEGITHSLCTLEFQDHRPFYDWIVEKVKSKAVPHQYESSRLNVDYTITSKRKLRK
HHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHH
LVEGGYVNGWDDPRMPTVVGMRRRGFTPEGLRDFCKRVGVSKTDGIVDVAMLEFCIRQSL
HHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ENTAARGMAVLNPLKVTLTNLPEDLDLTHARHPNVDMGERVIPLTKEIYIDRKDFEEVPP
HHHHHCCHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCHHHHEECCHHHHHCCC
KGFKRLIPDGEVRLRHAYVIKCDEVIKDANGEVIELKCSIDPDTLGKNPEGRKVKGVIHW
HHHHHCCCCCCEEEEEEEEEEHHHHHHCCCCCEEEEEECCCHHHCCCCCCCCEEEHEEEE
VSATKGIPAEVRIYDRLFTEADPETGDDFLANLNPDSLKVVQAVIEPALAQAKPEDRFQF
EHHCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHCEE
EREGYFVADQYDHTPEKPVFNRVLDLKDSFKPEKK
CCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKPNDVVSNLPNNPTPNTHASVDSAQQEQQAGLDFVRQVITDDLAAGRAKQIVTRFPPEP
CCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
NGYLHIGHVKAICLNFGVAEEFNGLCNLRFDDTNPDAEEQEYVDGIANDVKWLGFSWNGE
CCEEEECHHHHHHHHCCCHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCC
PRYASGYFDQLYAWAIQLIEQGDAYVDLQSPEEIKLNRGSFVEPGKNSPYRDASVEENLA
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHH
RFEKMRNGELKEGEAVLRAKIDMASPNVHMRDPILYRVLHSEHHQTGDKWKIYPMYDYAH
HHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHC
PLSDAIEGITHSLCTLEFQDHRPFYDWIVEKVKSKAVPHQYESSRLNVDYTITSKRKLRK
HHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHH
LVEGGYVNGWDDPRMPTVVGMRRRGFTPEGLRDFCKRVGVSKTDGIVDVAMLEFCIRQSL
HHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ENTAARGMAVLNPLKVTLTNLPEDLDLTHARHPNVDMGERVIPLTKEIYIDRKDFEEVPP
HHHHHCCHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCHHHHEECCHHHHHCCC
KGFKRLIPDGEVRLRHAYVIKCDEVIKDANGEVIELKCSIDPDTLGKNPEGRKVKGVIHW
HHHHHCCCCCCEEEEEEEEEEHHHHHHCCCCCEEEEEECCCHHHCCCCCCCCEEEHEEEE
VSATKGIPAEVRIYDRLFTEADPETGDDFLANLNPDSLKVVQAVIEPALAQAKPEDRFQF
EHHCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHCEE
EREGYFVADQYDHTPEKPVFNRVLDLKDSFKPEKK
CCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA