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The map label for this gene is lrp [H]

Identifier: 213158439

GI number: 213158439

Start: 2475477

End: 2475950

Strand: Reverse

Name: lrp [H]

Synonym: AB57_2388

Alternate gene names: 213158439

Gene position: 2475950-2475477 (Counterclockwise)

Preceding gene: 213158441

Following gene: 213158435

Centisome position: 61.13

GC content: 40.72

Gene sequence:

>474_bases
ATGGATGAGCAGGCTGAAAATTTAACACCTCTTGAATTGAAAATTATGCGCTGTTTACAAGAGAATGGACGTTTAAGTAA
TGCTGAACTGGCAAAACTTGTTGGCATTAGTACTTCGTCATGTTGGAACCATACTCAACGTCTTTTTAAGATTGGGGCCA
TCTTGGATGTACGTGCTCGAATCAATCCGGGTATGGTGCAACGTGAGACTATTGTTTTGGTCGGAGTAGTGCTGGATCGC
TCGACACCTGATAGCTTTCAGGCATTTGAACAAGCAGCAGGTGATTTAGAGAATGTTCTTGAATGTTACTTGGTTGCCGG
AGAAGTCGACTACTTTCTAAAAATTCGTGTTAAAGATTTGGCTGCTTTTAACCGTTTTCATAGTGAAAAAATTATTGCCT
TACCCGGGGTAAGACAGGTGAGGACATTTTTTGTGCTCAATGAAGTTAAAACAGATGGCATGCTGGCATTTTAA

Upstream 100 bases:

>100_bases
TGCTTTCTATTTTTGGCTTTAAAATGAAAGAATATTTTTTAAATAGCCATTAATGGTATTATTTATTTCATAACAAACGG
GGAATTTGGGATATTGTTTT

Downstream 100 bases:

>100_bases
CAACTTAATAAATTCTGACTTCCTTGACTCGGCAGCTTACATTGTTGAAGTTGCCAGCTTTAAGCCAAATCCGAAAAATA
AAATGCCAACTAAGAAAATT

Product: leucine-responsive transcriptional regulator, AsnC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MDEQAENLTPLELKIMRCLQENGRLSNAELAKLVGISTSSCWNHTQRLFKIGAILDVRARINPGMVQRETIVLVGVVLDR
STPDSFQAFEQAAGDLENVLECYLVAGEVDYFLKIRVKDLAAFNRFHSEKIIALPGVRQVRTFFVLNEVKTDGMLAF

Sequences:

>Translated_157_residues
MDEQAENLTPLELKIMRCLQENGRLSNAELAKLVGISTSSCWNHTQRLFKIGAILDVRARINPGMVQRETIVLVGVVLDR
STPDSFQAFEQAAGDLENVLECYLVAGEVDYFLKIRVKDLAAFNRFHSEKIIALPGVRQVRTFFVLNEVKTDGMLAF
>Mature_157_residues
MDEQAENLTPLELKIMRCLQENGRLSNAELAKLVGISTSSCWNHTQRLFKIGAILDVRARINPGMVQRETIVLVGVVLDR
STPDSFQAFEQAAGDLENVLECYLVAGEVDYFLKIRVKDLAAFNRFHSEKIIALPGVRQVRTFFVLNEVKTDGMLAF

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=153, Percent_Identity=37.9084967320261, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=23.7762237762238, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17658; Mature: 17658

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQAENLTPLELKIMRCLQENGRLSNAELAKLVGISTSSCWNHTQRLFKIGAILDVRAR
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEEC
INPGMVQRETIVLVGVVLDRSTPDSFQAFEQAAGDLENVLECYLVAGEVDYFLKIRVKDL
CCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEEEHHHHH
AAFNRFHSEKIIALPGVRQVRTFFVLNEVKTDGMLAF
HHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MDEQAENLTPLELKIMRCLQENGRLSNAELAKLVGISTSSCWNHTQRLFKIGAILDVRAR
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEEC
INPGMVQRETIVLVGVVLDRSTPDSFQAFEQAAGDLENVLECYLVAGEVDYFLKIRVKDL
CCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEEEHHHHH
AAFNRFHSEKIIALPGVRQVRTFFVLNEVKTDGMLAF
HHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]