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The map label for this gene is fabG [H]

Identifier: 213158433

GI number: 213158433

Start: 2468916

End: 2470307

Strand: Reverse

Name: fabG [H]

Synonym: AB57_2382

Alternate gene names: 213158433

Gene position: 2470307-2468916 (Counterclockwise)

Preceding gene: 213158435

Following gene: 213158432

Centisome position: 60.99

GC content: 41.95

Gene sequence:

>1392_bases
ATGACTGATCAATACCAAGCATTTACGCAATCTCCTATTGGTAAATTCGTTGTTAAAAATCTGGGTTTACCTTCGCCTGT
TGTATTAGAGCGTTTTGAAAGTGCTCAGCCAGTAGTGAAAGGTGCAGTATTGGTTGGCGCGGCGCCGTCAAGCGTTTTGT
CTGGTGCGATTGCACAAGTACTTAGCAATATTCATGCAGATAGCTATGTAGGCAATAATGTTGCATTACAACAAGAAGCT
GCAAAAGTTGGTTTAAATTTACGTCCATTCAATGCAGGTGATAAAGAATCAAAATTCAAAGCTGTTGTATTTGATGCGTC
TGGTATTCAAAATTCAGAACAGTTAAACGAACTTTATAAATTCTTTAATCCGATTGCACGTCAAGTTGCGACTTCTGGTC
GAGTGATTGTTATTGGTACAACGCCAGAAACTGCAAAAACTGTGAAACAAGCGATTGCTCAGCGTGCACTTGAAGGCTTT
ATCAAATCTGTAGGTAAAGAATTTAAAAAGGGTATTACTGCTCAAGTTGTGTATGTAGACGAAGGTGCTGCTGCAAACCT
TGAATCAACATTACGTTTCTTGCTTTCTCCACGTTCAGCGTATGTTTCTGGTCAAGTAATTCGTGTATCTAAAGCAGATG
TAGTTGATGTTGATTGGGCAAAACCGCTTGCTGGAAAAACTGCGTTAGTAACTGGTGCAAGCCGTGGTATTGGTGAGGCA
ATTGCACATGTGTTGGCACGTGATGGTGCGCATGTTATTTGTCTAGACGTACCACAACAACAAGCTGACCTTGACCGTGT
AGCTGCTGACATTGGTGGTTCTACATTGGCAATTGACATTACAGCTGCTGATGCGGGCGAAAAAATTAAAGCTGCTGCGG
CTAAACAAGGCGGTTTAGATATTATTGTTCATAACGCAGGTATTACACGTGACAAAACTTTGGCAAACATGAAGCCAGAG
CTTTGGGACTTAGTCATTAACATTAACTTGTCTGCTGCTGAACGCGTAAACGACTACTTGTTAGAAAACGATGGTCTAAA
TGCAAATGGCCGCATTGTTTGTGTATCATCAATTAGTGGTATTGCTGGTAACCTTGGTCAAACCAACTATGCTGCATCTA
AAGCAGGTGTAATTGGCCTAGTGAAATTTACTGCGCCTATTCTAAAAAATGGTATTACCATTAACGCAGTAGCACCTGGC
TTTATCGAGACCCAAATGACTGCTGCGATTCCATTTGCGATTCGTGAAGCTGGTCGCCGTATGAACTCAATGCAACAAGG
TGGTTTACCTGTTGATGTAGCAGAAACGATTGCATGGTTTGCATCAACTGCTTCTACAGGTGTAAATGGCAACGTTGTAC
GCGTGTGCGGTCAAAGCTTGTTGGGCGCTTAA

Upstream 100 bases:

>100_bases
GAGTAACTCTAATGAACGACTGCTTTCATATTGTTTCTATCCATCTCATAACATAATGAAGCCTGTCGTAGAAAATTCAT
TTCTTTGAGAGATAATAATC

Downstream 100 bases:

>100_bases
GCACTTTTAGCTAAATAGGGGTGCTTGTGCATCCCTTTTTTATTCAAGAATTTATAAATTATAAAAGGTTAGGTATGAAT
ACTCGTCATTTTAGCCAGCT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTDQYQAFTQSPIGKFVVKNLGLPSPVVLERFESAQPVVKGAVLVGAAPSSVLSGAIAQVLSNIHADSYVGNNVALQQEA
AKVGLNLRPFNAGDKESKFKAVVFDASGIQNSEQLNELYKFFNPIARQVATSGRVIVIGTTPETAKTVKQAIAQRALEGF
IKSVGKEFKKGITAQVVYVDEGAAANLESTLRFLLSPRSAYVSGQVIRVSKADVVDVDWAKPLAGKTALVTGASRGIGEA
IAHVLARDGAHVICLDVPQQQADLDRVAADIGGSTLAIDITAADAGEKIKAAAAKQGGLDIIVHNAGITRDKTLANMKPE
LWDLVININLSAAERVNDYLLENDGLNANGRIVCVSSISGIAGNLGQTNYAASKAGVIGLVKFTAPILKNGITINAVAPG
FIETQMTAAIPFAIREAGRRMNSMQQGGLPVDVAETIAWFASTASTGVNGNVVRVCGQSLLGA

Sequences:

>Translated_463_residues
MTDQYQAFTQSPIGKFVVKNLGLPSPVVLERFESAQPVVKGAVLVGAAPSSVLSGAIAQVLSNIHADSYVGNNVALQQEA
AKVGLNLRPFNAGDKESKFKAVVFDASGIQNSEQLNELYKFFNPIARQVATSGRVIVIGTTPETAKTVKQAIAQRALEGF
IKSVGKEFKKGITAQVVYVDEGAAANLESTLRFLLSPRSAYVSGQVIRVSKADVVDVDWAKPLAGKTALVTGASRGIGEA
IAHVLARDGAHVICLDVPQQQADLDRVAADIGGSTLAIDITAADAGEKIKAAAAKQGGLDIIVHNAGITRDKTLANMKPE
LWDLVININLSAAERVNDYLLENDGLNANGRIVCVSSISGIAGNLGQTNYAASKAGVIGLVKFTAPILKNGITINAVAPG
FIETQMTAAIPFAIREAGRRMNSMQQGGLPVDVAETIAWFASTASTGVNGNVVRVCGQSLLGA
>Mature_462_residues
TDQYQAFTQSPIGKFVVKNLGLPSPVVLERFESAQPVVKGAVLVGAAPSSVLSGAIAQVLSNIHADSYVGNNVALQQEAA
KVGLNLRPFNAGDKESKFKAVVFDASGIQNSEQLNELYKFFNPIARQVATSGRVIVIGTTPETAKTVKQAIAQRALEGFI
KSVGKEFKKGITAQVVYVDEGAAANLESTLRFLLSPRSAYVSGQVIRVSKADVVDVDWAKPLAGKTALVTGASRGIGEAI
AHVLARDGAHVICLDVPQQQADLDRVAADIGGSTLAIDITAADAGEKIKAAAAKQGGLDIIVHNAGITRDKTLANMKPEL
WDLVININLSAAERVNDYLLENDGLNANGRIVCVSSISGIAGNLGQTNYAASKAGVIGLVKFTAPILKNGITINAVAPGF
IETQMTAAIPFAIREAGRRMNSMQQGGLPVDVAETIAWFASTASTGVNGNVVRVCGQSLLGA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=37.890625, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=31.1740890688259, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4504505, Length=243, Percent_Identity=32.5102880658436, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=29.5275590551181, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=31.25, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI33667109, Length=203, Percent_Identity=31.5270935960591, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI126723191, Length=166, Percent_Identity=34.3373493975904, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=32.3383084577114, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI126723750, Length=270, Percent_Identity=27.037037037037, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=40.5737704918033, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=32.9411764705882, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=28.968253968254, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=27.1255060728745, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=32.5301204819277, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=30.379746835443, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787526, Length=197, Percent_Identity=29.9492385786802, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789378, Length=261, Percent_Identity=29.1187739463602, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=39.1666666666667, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17555706, Length=242, Percent_Identity=36.3636363636364, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17568967, Length=167, Percent_Identity=35.9281437125749, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=215, Percent_Identity=33.4883720930233, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=212, Percent_Identity=31.6037735849057, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=27.0588235294118, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=29.5454545454545, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=29.6747967479675, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=249, Percent_Identity=30.5220883534137, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=29.4354838709677, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=26.7206477732794, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=250, Percent_Identity=30, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=245, Percent_Identity=27.7551020408163, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=230, Percent_Identity=27.8260869565217, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=30, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=244, Percent_Identity=29.0983606557377, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=208, Percent_Identity=29.8076923076923, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=37.2950819672131, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=33.469387755102, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18859837, Length=188, Percent_Identity=34.0425531914894, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17737361, Length=250, Percent_Identity=33.2, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355319, Length=202, Percent_Identity=32.1782178217822, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=32.6530612244898, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357041, Length=241, Percent_Identity=29.4605809128631, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=31.3008130081301, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=27.0408163265306, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=242, Percent_Identity=30.5785123966942, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 48355; Mature: 48224

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQYQAFTQSPIGKFVVKNLGLPSPVVLERFESAQPVVKGAVLVGAAPSSVLSGAIAQV
CCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHCEEEEECCCHHHHHHHHHHH
LSNIHADSYVGNNVALQQEAAKVGLNLRPFNAGDKESKFKAVVFDASGIQNSEQLNELYK
HHHHCCCCCCCCCEEEHHHHHHHCCEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHH
FFNPIARQVATSGRVIVIGTTPETAKTVKQAIAQRALEGFIKSVGKEFKKGITAQVVYVD
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
EGAAANLESTLRFLLSPRSAYVSGQVIRVSKADVVDVDWAKPLAGKTALVTGASRGIGEA
CCCCCCHHHHHHHHHCCCHHHCCCEEEEEECCCEEECCCCCCCCCCEEEEECCCCCHHHH
IAHVLARDGAHVICLDVPQQQADLDRVAADIGGSTLAIDITAADAGEKIKAAAAKQGGLD
HHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHCCCCCE
IIVHNAGITRDKTLANMKPELWDLVININLSAAERVNDYLLENDGLNANGRIVCVSSISG
EEEECCCCCCCCHHHCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
IAGNLGQTNYAASKAGVIGLVKFTAPILKNGITINAVAPGFIETQMTAAIPFAIREAGRR
HHCCCCCCCCCCCCCCEEEEHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
MNSMQQGGLPVDVAETIAWFASTASTGVNGNVVRVCGQSLLGA
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TDQYQAFTQSPIGKFVVKNLGLPSPVVLERFESAQPVVKGAVLVGAAPSSVLSGAIAQV
CCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHCEEEEECCCHHHHHHHHHHH
LSNIHADSYVGNNVALQQEAAKVGLNLRPFNAGDKESKFKAVVFDASGIQNSEQLNELYK
HHHHCCCCCCCCCEEEHHHHHHHCCEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHH
FFNPIARQVATSGRVIVIGTTPETAKTVKQAIAQRALEGFIKSVGKEFKKGITAQVVYVD
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
EGAAANLESTLRFLLSPRSAYVSGQVIRVSKADVVDVDWAKPLAGKTALVTGASRGIGEA
CCCCCCHHHHHHHHHCCCHHHCCCEEEEEECCCEEECCCCCCCCCCEEEEECCCCCHHHH
IAHVLARDGAHVICLDVPQQQADLDRVAADIGGSTLAIDITAADAGEKIKAAAAKQGGLD
HHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHCCCCCE
IIVHNAGITRDKTLANMKPELWDLVININLSAAERVNDYLLENDGLNANGRIVCVSSISG
EEEECCCCCCCCHHHCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
IAGNLGQTNYAASKAGVIGLVKFTAPILKNGITINAVAPGFIETQMTAAIPFAIREAGRR
HHCCCCCCCCCCCCCCEEEEHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
MNSMQQGGLPVDVAETIAWFASTASTGVNGNVVRVCGQSLLGA
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]