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The map label for this gene is lpxD [H]

Identifier: 213158366

GI number: 213158366

Start: 2395476

End: 2396546

Strand: Reverse

Name: lpxD [H]

Synonym: AB57_2312

Alternate gene names: 213158366

Gene position: 2396546-2395476 (Counterclockwise)

Preceding gene: 213158367

Following gene: 213158365

Centisome position: 59.17

GC content: 37.35

Gene sequence:

>1071_bases
ATGAAAGTGCAACAATATCGTTTAGATGAATTAACTCACCTTGTTAAAGGTGAGCTAATTGGTGAAGGTAGTCTTCAATT
TTCAAACTTGGCGAGTTTGGAAAATGCAGAGGTTAACCATCTTACTTTTGTGAATGGTGAGAAACATCTTGATCAAGCTA
AAGTAAGTCGTGCGGGCGCTTACATTGTTACCGCAGCTTTAAAAGAACATCTTCCTGAAAAAGATAATTTTATTATTGTT
GATAATCCCTATCTTGCGTTTGCAATCCTTACCCATGTATTTGATAAAAAGATTAGCTCAACAGGCATAGAAAGCACTGC
CCAAATTCATCCATCTGCTGTTATTTCCGAAACTGCTTATATTGGTCACTATGTGGTTATTGGTGAGAATTGTGTAGTTG
GCGATAATACCGTCATTCAGTCACATACCAAACTTGATGATAATGTAGAAGTTGGAAAAGACTGTTTTATTGATTCTCAT
GTCACTATTACAGGTGGTTCTAAATTACGAGATCGCGTCCGTATTCATTCAAGTACTGTCATTGGTGGAGAAGGTTTTGG
TTTTGCTCCATATCAAGGAAAGTGGCATCGTATTGCTCAATTAGGTTCAGTTTTAATTGGAAATGATGTCCGAATTGGAT
CAAATTGTAGTATTGATAGAGGCGCACTTGATAATACAATTTTGGAAGATGGGGTTATTATTGATAACCTTGTGCAAATT
GCACATAACGTCCATATTGGTTCAAATACTGCTATTGCAGCGAAGTGCGGTATTGCCGGAAGTACAAAAATTGGCAAAAA
CTGTATTCTAGCTGGGGCGTGTGGAGTGGCAGGACACCTTTCAATTGCTGATAATGTGACTTTGACTGGAATGTCAATGG
TCACAAAAAATATTTCTGAAGCTGGAACTTACTCTTCGGGAACCGGATTATTTGAAAATAATCATTGGAAAAAGACGATT
GTACGCTTGCGACAATTAGCAGATGTGCCATTGACCCAAATCACTAAACGACTTGATCATATACAAGCTCAAATAGAGTC
TCTTGAATCAACTTTTAATTTGCGTAAATAG

Upstream 100 bases:

>100_bases
CTTGACTTTATTTTGAATAAAAATTCGACTGTTGCCTATGACGCTAAGTATGATTTAACTGATAAAATGATACAAAAGGT
TAATTCAATGAAATAAATTA

Downstream 100 bases:

>100_bases
AATATTATGACCGAGTCTACTACACCTAAATTTGCCATCCCTGAATTACCAATGCAGATTCAAACGATTCGTCAATATTT
GCCGCATCGTTACCCATTCT

Product: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKVQQYRLDELTHLVKGELIGEGSLQFSNLASLENAEVNHLTFVNGEKHLDQAKVSRAGAYIVTAALKEHLPEKDNFIIV
DNPYLAFAILTHVFDKKISSTGIESTAQIHPSAVISETAYIGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKDCFIDSH
VTITGGSKLRDRVRIHSSTVIGGEGFGFAPYQGKWHRIAQLGSVLIGNDVRIGSNCSIDRGALDNTILEDGVIIDNLVQI
AHNVHIGSNTAIAAKCGIAGSTKIGKNCILAGACGVAGHLSIADNVTLTGMSMVTKNISEAGTYSSGTGLFENNHWKKTI
VRLRQLADVPLTQITKRLDHIQAQIESLESTFNLRK

Sequences:

>Translated_356_residues
MKVQQYRLDELTHLVKGELIGEGSLQFSNLASLENAEVNHLTFVNGEKHLDQAKVSRAGAYIVTAALKEHLPEKDNFIIV
DNPYLAFAILTHVFDKKISSTGIESTAQIHPSAVISETAYIGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKDCFIDSH
VTITGGSKLRDRVRIHSSTVIGGEGFGFAPYQGKWHRIAQLGSVLIGNDVRIGSNCSIDRGALDNTILEDGVIIDNLVQI
AHNVHIGSNTAIAAKCGIAGSTKIGKNCILAGACGVAGHLSIADNVTLTGMSMVTKNISEAGTYSSGTGLFENNHWKKTI
VRLRQLADVPLTQITKRLDHIQAQIESLESTFNLRK
>Mature_356_residues
MKVQQYRLDELTHLVKGELIGEGSLQFSNLASLENAEVNHLTFVNGEKHLDQAKVSRAGAYIVTAALKEHLPEKDNFIIV
DNPYLAFAILTHVFDKKISSTGIESTAQIHPSAVISETAYIGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKDCFIDSH
VTITGGSKLRDRVRIHSSTVIGGEGFGFAPYQGKWHRIAQLGSVLIGNDVRIGSNCSIDRGALDNTILEDGVIIDNLVQI
AHNVHIGSNTAIAAKCGIAGSTKIGKNCILAGACGVAGHLSIADNVTLTGMSMVTKNISEAGTYSSGTGLFENNHWKKTI
VRLRQLADVPLTQITKRLDHIQAQIESLESTFNLRK

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG1044

COG function: function code M; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786376, Length=352, Percent_Identity=39.4886363636364, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR011004
- InterPro:   IPR007691
- InterPro:   IPR020573 [H]

Pfam domain/function: PF00132 Hexapep; PF04613 LpxD [H]

EC number: 2.3.1.-

Molecular weight: Translated: 38430; Mature: 38430

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVQQYRLDELTHLVKGELIGEGSLQFSNLASLENAEVNHLTFVNGEKHLDQAKVSRAGA
CCCHHHHHHHHHHHHHCCEECCCCCCHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHCCH
YIVTAALKEHLPEKDNFIIVDNPYLAFAILTHVFDKKISSTGIESTAQIHPSAVISETAY
HEEEHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHE
IGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKDCFIDSHVTITGGSKLRDRVRIHSSTV
EEEEEEECCEEEECCCCEEECCCCCCCCCCCCCCEEECCEEEEECCHHHHHHHEEECCEE
IGGEGFGFAPYQGKWHRIAQLGSVLIGNDVRIGSNCSIDRGALDNTILEDGVIIDNLVQI
ECCCCCCCCCCCCHHHHHHHHCCEEECCCEEECCCCCCCCCCCCCHHHHCCCHHHHHHHH
AHNVHIGSNTAIAAKCGIAGSTKIGKNCILAGACGVAGHLSIADNVTLTGMSMVTKNISE
HHHEECCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCEEECCCEEEEHHHHHHHHHHH
AGTYSSGTGLFENNHWKKTIVRLRQLADVPLTQITKRLDHIQAQIESLESTFNLRK
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVQQYRLDELTHLVKGELIGEGSLQFSNLASLENAEVNHLTFVNGEKHLDQAKVSRAGA
CCCHHHHHHHHHHHHHCCEECCCCCCHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHCCH
YIVTAALKEHLPEKDNFIIVDNPYLAFAILTHVFDKKISSTGIESTAQIHPSAVISETAY
HEEEHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHE
IGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKDCFIDSHVTITGGSKLRDRVRIHSSTV
EEEEEEECCEEEECCCCEEECCCCCCCCCCCCCCEEECCEEEEECCHHHHHHHEEECCEE
IGGEGFGFAPYQGKWHRIAQLGSVLIGNDVRIGSNCSIDRGALDNTILEDGVIIDNLVQI
ECCCCCCCCCCCCHHHHHHHHCCEEECCCEEECCCCCCCCCCCCCHHHHCCCHHHHHHHH
AHNVHIGSNTAIAAKCGIAGSTKIGKNCILAGACGVAGHLSIADNVTLTGMSMVTKNISE
HHHEECCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCEEECCCEEEEHHHHHHHHHHH
AGTYSSGTGLFENNHWKKTIVRLRQLADVPLTQITKRLDHIQAQIESLESTFNLRK
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA