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The map label for this gene is pckG [H]

Identifier: 213158355

GI number: 213158355

Start: 3190452

End: 3192284

Strand: Direct

Name: pckG [H]

Synonym: AB57_3085

Alternate gene names: 213158355

Gene position: 3190452-3192284 (Clockwise)

Preceding gene: 213158348

Following gene: 213157611

Centisome position: 78.77

GC content: 42.83

Gene sequence:

>1833_bases
ATGACCACAGTGAACGCACCAGAATTCGTTCGTCATCCTAAGCTTATAGCATGGGTTGAAGAAATTGCAAACTTAACCAA
ACCAGCAAAAATCGAATGGTGTGACGGAAGCGAAGAAGAGTATCAACGTCTAATCGACTTGATGATCGCTAACGGCACCA
TGCAGAAATTAAACCAAGAAAAACATCCTGGTTCTTATCTTGCAAATTCTGACCCATCTGATGTTGCGCGTGTTGAAGAT
CGTACTTACATCTGCTCTCAAAATAAAGAAGATGCTGGTGCGACAAACAACTGGGAAGATCCAGCTGTTATGCGTGAAAA
ATTAAATGGTTTATTTGAAGGTTCAATGAAAGGCCGTACCATGTACGTTGTTCCTTTCTCTATGGGTCCTTTAGGTAGCC
ATATTGCTCACATTGGTATCGAGTTAACTGACTCTCCTTATGTAGCTGTTAGCATGCGCAAAATGGCACGTATGGGTAAA
GCAGTTTATGACGTATTAGGTACAGATGGCGAGTTTGTTCCTTGCGTACATACAGTAGGTGCTCCACTTGCTGAAGGTCA
AAAAGATGTTGCTTGGCCTTGTAACCCAGAGAAATATATCGTTCATTACCCAGAAACTCGCGAAATCTGGTCTTTCGGTT
CTGGTTACGGCGGTAACGCGTTACTTGGTAAAAAATGTTTAGCTCTTCGTATCGCTTCTGTCATGGGACGCGAACAAGGT
TGGTTAGCTGAACACATGCTTATTCTTGGTGTAACTAACCCTCAAGGTGAAAAACACTACATCGCTGCTGCATTCCCATC
TGCTTGTGGTAAAACAAACTTTGCAATGTTAATTCCACCAGCAGGTTATGAAGGTTGGAAAATCGAAACTGTAGGTGACG
ATATTGCTTGGATTAAACCAGGTGAAGATGGTCGCTTATATGCAATTAACCCTGAAGCTGGTTTCTTCGGTGTAGCACCT
GGTACAAATACCAAAACTAACCCGAACTGTATGGCAACTCTTCACAAAGACGTTATCTATACAAACGTAGCAGTAACTGA
CGATGGTCAAGTATGGTGGGAAGGTCTTTCTAAAGAAGTTCCAGCAAACTTAACTAACTGGAAAGGTCAACCTCACGTAA
ACGGCGAAAAAGCAGCACATCCAAATGCTCGTTTCACTGTTGCAGCAGGTCAATGTCCATCTATCGATGCTGATTGGGAA
AACCCAGCAGGTGTGCCAATTTCTGCATTCATCTTCGGTGGCCGTCGTGCAGATACAGTACCTTTAGTTTCTGAAGCTTT
CGACTGGGTTGACGGTGTATATAAAGCGGCAACTATGGGTTCTGAAACTACTGCTGCTGCTGTTGGTCAACAAGGTATTG
TTCGCCGTGACCCATTCGCGATGCTTCCATTTGCTGGCTATAACATGGCTGACTACTTTGACCACTGGTTAAACCTTGGT
GCGAAAGTAAGTGAAAAAGCTGAAGCTTCTGGCAACAAATTACCAAAAATCTTCAATGTAAACTGGTTCCGTCGTGATGC
TGAAGGCAACTTCGTATGGCCTGGTTTTGGTCAAAACATGCGTGTTCTTGAGTGGATCATTGATCGTTGTGAAGGTCGTG
CAAACGCTGTTGAAACACCTATCGGTTTTGTTCCAACATATGAAGACTTGAATTGGGAAGGTACTGAGTTCACTAAAGAA
CAATTTGACCTCATCACAAATCAAGATAGAGACCAATGGGTTACTGAAATTGAAAGCCACACTGAGTTATTCAATAAACT
TGGCGAACGCTTACCTAAGGCATTAAAAGAACGTCAAGCAGCTTTACTTGAAGCTGTAAAAACTGGCTTCTAA

Upstream 100 bases:

>100_bases
TTATGATTTTATGCTTTAATACAGCCACTTTTTTATTTGATCTTTCATTGTATCCCAATGAATGACTTGTACGTTGTACA
TATTTTGAATAGGCCTCACC

Downstream 100 bases:

>100_bases
TTGCTCTATATAAAAAAGGTCGCCATGTGCGACCTTTTTTATTATGCGGCATCATCTTTTAATCGACGTTCTGATAAATA
AGCTTCTAAAACTTTTACCT

Product: phosphoenolpyruvate carboxykinase

Products: NA

Alternate protein names: PEP carboxykinase; PEPCK; Phosphoenolpyruvate carboxylase [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MTTVNAPEFVRHPKLIAWVEEIANLTKPAKIEWCDGSEEEYQRLIDLMIANGTMQKLNQEKHPGSYLANSDPSDVARVED
RTYICSQNKEDAGATNNWEDPAVMREKLNGLFEGSMKGRTMYVVPFSMGPLGSHIAHIGIELTDSPYVAVSMRKMARMGK
AVYDVLGTDGEFVPCVHTVGAPLAEGQKDVAWPCNPEKYIVHYPETREIWSFGSGYGGNALLGKKCLALRIASVMGREQG
WLAEHMLILGVTNPQGEKHYIAAAFPSACGKTNFAMLIPPAGYEGWKIETVGDDIAWIKPGEDGRLYAINPEAGFFGVAP
GTNTKTNPNCMATLHKDVIYTNVAVTDDGQVWWEGLSKEVPANLTNWKGQPHVNGEKAAHPNARFTVAAGQCPSIDADWE
NPAGVPISAFIFGGRRADTVPLVSEAFDWVDGVYKAATMGSETTAAAVGQQGIVRRDPFAMLPFAGYNMADYFDHWLNLG
AKVSEKAEASGNKLPKIFNVNWFRRDAEGNFVWPGFGQNMRVLEWIIDRCEGRANAVETPIGFVPTYEDLNWEGTEFTKE
QFDLITNQDRDQWVTEIESHTELFNKLGERLPKALKERQAALLEAVKTGF

Sequences:

>Translated_610_residues
MTTVNAPEFVRHPKLIAWVEEIANLTKPAKIEWCDGSEEEYQRLIDLMIANGTMQKLNQEKHPGSYLANSDPSDVARVED
RTYICSQNKEDAGATNNWEDPAVMREKLNGLFEGSMKGRTMYVVPFSMGPLGSHIAHIGIELTDSPYVAVSMRKMARMGK
AVYDVLGTDGEFVPCVHTVGAPLAEGQKDVAWPCNPEKYIVHYPETREIWSFGSGYGGNALLGKKCLALRIASVMGREQG
WLAEHMLILGVTNPQGEKHYIAAAFPSACGKTNFAMLIPPAGYEGWKIETVGDDIAWIKPGEDGRLYAINPEAGFFGVAP
GTNTKTNPNCMATLHKDVIYTNVAVTDDGQVWWEGLSKEVPANLTNWKGQPHVNGEKAAHPNARFTVAAGQCPSIDADWE
NPAGVPISAFIFGGRRADTVPLVSEAFDWVDGVYKAATMGSETTAAAVGQQGIVRRDPFAMLPFAGYNMADYFDHWLNLG
AKVSEKAEASGNKLPKIFNVNWFRRDAEGNFVWPGFGQNMRVLEWIIDRCEGRANAVETPIGFVPTYEDLNWEGTEFTKE
QFDLITNQDRDQWVTEIESHTELFNKLGERLPKALKERQAALLEAVKTGF
>Mature_609_residues
TTVNAPEFVRHPKLIAWVEEIANLTKPAKIEWCDGSEEEYQRLIDLMIANGTMQKLNQEKHPGSYLANSDPSDVARVEDR
TYICSQNKEDAGATNNWEDPAVMREKLNGLFEGSMKGRTMYVVPFSMGPLGSHIAHIGIELTDSPYVAVSMRKMARMGKA
VYDVLGTDGEFVPCVHTVGAPLAEGQKDVAWPCNPEKYIVHYPETREIWSFGSGYGGNALLGKKCLALRIASVMGREQGW
LAEHMLILGVTNPQGEKHYIAAAFPSACGKTNFAMLIPPAGYEGWKIETVGDDIAWIKPGEDGRLYAINPEAGFFGVAPG
TNTKTNPNCMATLHKDVIYTNVAVTDDGQVWWEGLSKEVPANLTNWKGQPHVNGEKAAHPNARFTVAAGQCPSIDADWEN
PAGVPISAFIFGGRRADTVPLVSEAFDWVDGVYKAATMGSETTAAAVGQQGIVRRDPFAMLPFAGYNMADYFDHWLNLGA
KVSEKAEASGNKLPKIFNVNWFRRDAEGNFVWPGFGQNMRVLEWIIDRCEGRANAVETPIGFVPTYEDLNWEGTEFTKEQ
FDLITNQDRDQWVTEIESHTELFNKLGERLPKALKERQAALLEAVKTGF

Specific function: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle [H]

COG id: COG1274

COG function: function code C; Phosphoenolpyruvate carboxykinase (GTP)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family [H]

Homologues:

Organism=Homo sapiens, GI187281517, Length=615, Percent_Identity=50.4065040650407, Blast_Score=585, Evalue=1e-167,
Organism=Homo sapiens, GI66346721, Length=607, Percent_Identity=50.4118616144975, Blast_Score=583, Evalue=1e-166,
Organism=Homo sapiens, GI66346723, Length=387, Percent_Identity=51.937984496124, Blast_Score=390, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17555492, Length=622, Percent_Identity=48.7138263665595, Blast_Score=565, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71989645, Length=613, Percent_Identity=48.4502446982055, Blast_Score=564, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71989658, Length=613, Percent_Identity=48.4502446982055, Blast_Score=563, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71989653, Length=600, Percent_Identity=48.8333333333333, Blast_Score=557, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI32564411, Length=564, Percent_Identity=50.886524822695, Blast_Score=548, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI32564407, Length=519, Percent_Identity=52.2157996146435, Blast_Score=513, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI71989649, Length=482, Percent_Identity=52.2821576763486, Blast_Score=490, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI32564409, Length=375, Percent_Identity=48.8, Blast_Score=335, Evalue=5e-92,
Organism=Caenorhabditis elegans, GI17540956, Length=629, Percent_Identity=25.1192368839428, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24655085, Length=607, Percent_Identity=49.2586490939045, Blast_Score=569, Evalue=1e-162,
Organism=Drosophila melanogaster, GI24655082, Length=606, Percent_Identity=48.5148514851485, Blast_Score=561, Evalue=1e-160,
Organism=Drosophila melanogaster, GI161077226, Length=571, Percent_Identity=49.5621716287215, Blast_Score=536, Evalue=1e-152,
Organism=Drosophila melanogaster, GI24655088, Length=503, Percent_Identity=52.0874751491054, Blast_Score=507, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018091
- InterPro:   IPR013035
- InterPro:   IPR008209
- InterPro:   IPR008210 [H]

Pfam domain/function: PF00821 PEPCK [H]

EC number: =4.1.1.32 [H]

Molecular weight: Translated: 67449; Mature: 67318

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00505 PEPCK_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVNAPEFVRHPKLIAWVEEIANLTKPAKIEWCDGSEEEYQRLIDLMIANGTMQKLNQE
CCCCCCHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHCCC
KHPGSYLANSDPSDVARVEDRTYICSQNKEDAGATNNWEDPAVMREKLNGLFEGSMKGRT
CCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCE
MYVVPFSMGPLGSHIAHIGIELTDSPYVAVSMRKMARMGKAVYDVLGTDGEFVPCVHTVG
EEEEEECCCCCHHHHEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCEECHHHHCC
APLAEGQKDVAWPCNPEKYIVHYPETREIWSFGSGYGGNALLGKKCLALRIASVMGREQG
CCHHCCCCCCCCCCCCCCEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
WLAEHMLILGVTNPQGEKHYIAAAFPSACGKTNFAMLIPPAGYEGWKIETVGDDIAWIKP
CHHHEEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCEEEEECCCCEEEECC
GEDGRLYAINPEAGFFGVAPGTNTKTNPNCMATLHKDVIYTNVAVTDDGQVWWEGLSKEV
CCCCEEEEECCCCCEEECCCCCCCCCCCHHHHEEHHCEEEEEEEEECCCHHHHHCCCCCC
PANLTNWKGQPHVNGEKAAHPNARFTVAAGQCPSIDADWENPAGVPISAFIFGGRRADTV
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
PLVSEAFDWVDGVYKAATMGSETTAAAVGQQGIVRRDPFAMLPFAGYNMADYFDHWLNLG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEECCCCEECCCCCCCHHHHHHHHHHCC
AKVSEKAEASGNKLPKIFNVNWFRRDAEGNFVWPGFGQNMRVLEWIIDRCEGRANAVETP
CCCCHHHHCCCCCCCEEEECCEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCC
IGFVPTYEDLNWEGTEFTKEQFDLITNQDRDQWVTEIESHTELFNKLGERLPKALKERQA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLEAVKTGF
HHHHHHHHCC
>Mature Secondary Structure 
TTVNAPEFVRHPKLIAWVEEIANLTKPAKIEWCDGSEEEYQRLIDLMIANGTMQKLNQE
CCCCCHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHCCC
KHPGSYLANSDPSDVARVEDRTYICSQNKEDAGATNNWEDPAVMREKLNGLFEGSMKGRT
CCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCE
MYVVPFSMGPLGSHIAHIGIELTDSPYVAVSMRKMARMGKAVYDVLGTDGEFVPCVHTVG
EEEEEECCCCCHHHHEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCEECHHHHCC
APLAEGQKDVAWPCNPEKYIVHYPETREIWSFGSGYGGNALLGKKCLALRIASVMGREQG
CCHHCCCCCCCCCCCCCCEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
WLAEHMLILGVTNPQGEKHYIAAAFPSACGKTNFAMLIPPAGYEGWKIETVGDDIAWIKP
CHHHEEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCEEEEECCCCEEEECC
GEDGRLYAINPEAGFFGVAPGTNTKTNPNCMATLHKDVIYTNVAVTDDGQVWWEGLSKEV
CCCCEEEEECCCCCEEECCCCCCCCCCCHHHHEEHHCEEEEEEEEECCCHHHHHCCCCCC
PANLTNWKGQPHVNGEKAAHPNARFTVAAGQCPSIDADWENPAGVPISAFIFGGRRADTV
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
PLVSEAFDWVDGVYKAATMGSETTAAAVGQQGIVRRDPFAMLPFAGYNMADYFDHWLNLG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEECCCCEECCCCCCCHHHHHHHHHHCC
AKVSEKAEASGNKLPKIFNVNWFRRDAEGNFVWPGFGQNMRVLEWIIDRCEGRANAVETP
CCCCHHHHCCCCCCCEEEECCEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCC
IGFVPTYEDLNWEGTEFTKEQFDLITNQDRDQWVTEIESHTELFNKLGERLPKALKERQA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLEAVKTGF
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA