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The map label for this gene is yrhP [H]

Identifier: 213158314

GI number: 213158314

Start: 3136348

End: 3136971

Strand: Direct

Name: yrhP [H]

Synonym: AB57_3041

Alternate gene names: 213158314

Gene position: 3136348-3136971 (Clockwise)

Preceding gene: 213158309

Following gene: 213158320

Centisome position: 77.43

GC content: 39.42

Gene sequence:

>624_bases
ATGACCGCTATACTCATTCCTTATTTAATTGCCATTACTTTACTTACCCTTACCCCTGGTTTAGATACAACTTTAATTAT
TCGTACTGCAACACTTGAAGGAAAATCTAAAGCGTTTCAAGCAGCTCTAGGAATTAGTCTTGGCTGTATTGCTTGGGGAA
TTGTCGTGGCATGCGGTCTAGGTGCCCTACTGATGGCATCCGACTTAGCATTCAATATATTGAAATGGATGGGCGCCGCT
TATTTAGCATGGTTGGGTTTAAATATGATTTTAAAACCTCGTAGTCAGCTCGCAGATATACAAGACAATCATTCAAATCT
CTCTACTTCAGAGAATTGGTTTATTAAAGGTTTCTTTGGCAACTTGCTGAATCCAAAAGTTGGAATTTTTTATATTTCAT
TTCTTCCCCAGTTCATTCCAGCGCAAGCATCGGCTGTTACTTGGGTGATGGGGCTAGTAATGATTCATGTGGTGATTGGC
GTGTTATGGTCAAGTCTATTAATTCTGGCTATGCAGCCACTTTCGCGCTATCTAAAGCAACCCAAGTTTGTAAAATATAT
GGACCGAATTACGGGCAGTATTTTTGTTCTATTCGCTTTGAAATTGGCGTTGAGTAAAAGGTAA

Upstream 100 bases:

>100_bases
TACCAAAAACTATTTAATCAGGAAAATTTGATATCGCACAGCATAATGAATCCAACTTATATATTACAATTTATACTAAG
TATCCGTTGGACCTTACACC

Downstream 100 bases:

>100_bases
GTTTTTAAAAGCGTGCTAACACATAGCACGCTAAATAACGCTTAAAAAACTTACATTAGCCCTTTTAAGTAATTTTCTAT
TTGAACTGCAACTTCATCGG

Product: lysine exporter protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MTAILIPYLIAITLLTLTPGLDTTLIIRTATLEGKSKAFQAALGISLGCIAWGIVVACGLGALLMASDLAFNILKWMGAA
YLAWLGLNMILKPRSQLADIQDNHSNLSTSENWFIKGFFGNLLNPKVGIFYISFLPQFIPAQASAVTWVMGLVMIHVVIG
VLWSSLLILAMQPLSRYLKQPKFVKYMDRITGSIFVLFALKLALSKR

Sequences:

>Translated_207_residues
MTAILIPYLIAITLLTLTPGLDTTLIIRTATLEGKSKAFQAALGISLGCIAWGIVVACGLGALLMASDLAFNILKWMGAA
YLAWLGLNMILKPRSQLADIQDNHSNLSTSENWFIKGFFGNLLNPKVGIFYISFLPQFIPAQASAVTWVMGLVMIHVVIG
VLWSSLLILAMQPLSRYLKQPKFVKYMDRITGSIFVLFALKLALSKR
>Mature_206_residues
TAILIPYLIAITLLTLTPGLDTTLIIRTATLEGKSKAFQAALGISLGCIAWGIVVACGLGALLMASDLAFNILKWMGAAY
LAWLGLNMILKPRSQLADIQDNHSNLSTSENWFIKGFFGNLLNPKVGIFYISFLPQFIPAQASAVTWVMGLVMIHVVIGV
LWSSLLILAMQPLSRYLKQPKFVKYMDRITGSIFVLFALKLALSKR

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=204, Percent_Identity=29.9019607843137, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1788099, Length=203, Percent_Identity=25.615763546798, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22705; Mature: 22574

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAILIPYLIAITLLTLTPGLDTTLIIRTATLEGKSKAFQAALGISLGCIAWGIVVACGL
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
GALLMASDLAFNILKWMGAAYLAWLGLNMILKPRSQLADIQDNHSNLSTSENWFIKGFFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEHHH
NLLNPKVGIFYISFLPQFIPAQASAVTWVMGLVMIHVVIGVLWSSLLILAMQPLSRYLKQ
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PKFVKYMDRITGSIFVLFALKLALSKR
CHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAILIPYLIAITLLTLTPGLDTTLIIRTATLEGKSKAFQAALGISLGCIAWGIVVACGL
CHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
GALLMASDLAFNILKWMGAAYLAWLGLNMILKPRSQLADIQDNHSNLSTSENWFIKGFFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEHHH
NLLNPKVGIFYISFLPQFIPAQASAVTWVMGLVMIHVVIGVLWSSLLILAMQPLSRYLKQ
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PKFVKYMDRITGSIFVLFALKLALSKR
CHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]