Click here to switch to the map view.

The map label for this gene is serC

Identifier: 213158301

GI number: 213158301

Start: 3119658

End: 3120737

Strand: Reverse

Name: serC

Synonym: AB57_3027

Alternate gene names: 213158301

Gene position: 3120737-3119658 (Counterclockwise)

Preceding gene: 213158310

Following gene: 213158299

Centisome position: 77.05

GC content: 39.07

Gene sequence:

>1080_bases
ATGCGCGCGTACAATTTCTGTGCTGGTCCTGCTGCATTACCTACTGCCGTTTTAGAAAAAGCTCAACAAGAATTGTTGGA
TTGGCAAGGTAAGGGTCTATCCATCATGGAAATGAGTCACCGTAGTGCTGACTATGTTGCTGTTGCGGAAAAAGCTGAAG
CAGATTTGCGTAAGCTCATGAATATTCCTGAAAACTATAAAGTGCTATTTTTACAAGGTGGCGCGTCATTACAATTTTCA
GCAATTCCTTTAAACCTGCTTGGAAAAAATAACAAAGCAGATTATATCCATACTGGAATTTGGTCTGAAAAAGCTTTAAA
AGAAGCAAAACGTTATGGCGATATTAATGTTGTAGAAGCTGGTATTAAAGTAGACGGTAAGTTCGCAATTTCTGAGCAAA
GCGAATGGAACTTGTCTGACGATGCAGCTTATGTCCATTATGCTGATAACGAAACAATTGGCGGTTTACAGTTTGCTGGC
GTTCCTGATGTTAAAGCACCACTGGTATGTGACTTCTCATCAAGCATTTTATCTGCTCCACTTGATGTTTCGAAATTTGG
TCTCATCTATGCAGGTGCGCAAAAAAATATTGGTCCTGCTGGTTTAACAATTGTTATTATCCGTGATGACTTACTGGATC
AAGCTAAAGCAGAGATTCCAAGCATTTTAAAATATGCCGATCAAGCCAAGAATGGTTCTATGGTAAATACACCATCGACT
TATGCTTGGTACTTGTCTGGTTTAGTATTTGAATGGTTACTAGAGCAGGGTGGGGTAGATGCTATCCATAAAGTTAACCT
TGAAAAAGCTCAGTTACTCTATGGTTATATCGATTCAAGCGACTTTTATAATAACCCGATTGCCATTCCAAATCGTTCAA
TTATGAATGTACCATTTACTTTGGCAGATGAAGCTTTAGAAAAGCAATTCTTGAAAGAAGCTGAAGCAAATCACTTATTG
AACTTAGCAGGTCACCGCTCAGTAGGTGGTATGCGTGCAAGTATTTATAACGCTGTACCATTAGAAGGCGTTCAGGCGCT
TATCCGCTTTATGGATGATTTTGCTAAACGTAATGGTTAA

Upstream 100 bases:

>100_bases
CCTAGCATTGAAATATTTACTAGAGAAGCTGCTGCAACCTTAAGCAATCTGTGGTTAAATGCCTTTTTTTATTGTGTTTC
ACTTTTACAAGGGAAAAATC

Downstream 100 bases:

>100_bases
GTTATAAAATGAATAAAGCCCTCAAAAAGAGGGCTTTATTTTTATATAAATGATCAATTAAAAAGGCATAAAACCAAATT
GATGTATCATCATTGCGGCT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRAYNFCAGPAALPTAVLEKAQQELLDWQGKGLSIMEMSHRSADYVAVAEKAEADLRKLMNIPENYKVLFLQGGASLQFS
AIPLNLLGKNNKADYIHTGIWSEKALKEAKRYGDINVVEAGIKVDGKFAISEQSEWNLSDDAAYVHYADNETIGGLQFAG
VPDVKAPLVCDFSSSILSAPLDVSKFGLIYAGAQKNIGPAGLTIVIIRDDLLDQAKAEIPSILKYADQAKNGSMVNTPST
YAWYLSGLVFEWLLEQGGVDAIHKVNLEKAQLLYGYIDSSDFYNNPIAIPNRSIMNVPFTLADEALEKQFLKEAEANHLL
NLAGHRSVGGMRASIYNAVPLEGVQALIRFMDDFAKRNG

Sequences:

>Translated_359_residues
MRAYNFCAGPAALPTAVLEKAQQELLDWQGKGLSIMEMSHRSADYVAVAEKAEADLRKLMNIPENYKVLFLQGGASLQFS
AIPLNLLGKNNKADYIHTGIWSEKALKEAKRYGDINVVEAGIKVDGKFAISEQSEWNLSDDAAYVHYADNETIGGLQFAG
VPDVKAPLVCDFSSSILSAPLDVSKFGLIYAGAQKNIGPAGLTIVIIRDDLLDQAKAEIPSILKYADQAKNGSMVNTPST
YAWYLSGLVFEWLLEQGGVDAIHKVNLEKAQLLYGYIDSSDFYNNPIAIPNRSIMNVPFTLADEALEKQFLKEAEANHLL
NLAGHRSVGGMRASIYNAVPLEGVQALIRFMDDFAKRNG
>Mature_359_residues
MRAYNFCAGPAALPTAVLEKAQQELLDWQGKGLSIMEMSHRSADYVAVAEKAEADLRKLMNIPENYKVLFLQGGASLQFS
AIPLNLLGKNNKADYIHTGIWSEKALKEAKRYGDINVVEAGIKVDGKFAISEQSEWNLSDDAAYVHYADNETIGGLQFAG
VPDVKAPLVCDFSSSILSAPLDVSKFGLIYAGAQKNIGPAGLTIVIIRDDLLDQAKAEIPSILKYADQAKNGSMVNTPST
YAWYLSGLVFEWLLEQGGVDAIHKVNLEKAQLLYGYIDSSDFYNNPIAIPNRSIMNVPFTLADEALEKQFLKEAEANHLL
NLAGHRSVGGMRASIYNAVPLEGVQALIRFMDDFAKRNG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=51.5235457063712, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI10863955, Length=356, Percent_Identity=45.7865168539326, Blast_Score=306, Evalue=2e-83,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=58.9385474860335, Blast_Score=432, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=43.0939226519337, Blast_Score=303, Evalue=8e-83,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=42.2279792746114, Blast_Score=267, Evalue=2e-72,
Organism=Drosophila melanogaster, GI21356589, Length=361, Percent_Identity=49.8614958448753, Blast_Score=358, Evalue=2e-99,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SERC_ACIB3 (B7GY87)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002324777.1
- GeneID:   7059381
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_000864
- HOGENOM:   HBG289982
- OMA:   TFAWYLA
- ProtClustDB:   PRK05355
- GO:   GO:0005737
- HAMAP:   MF_00160
- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000525
- TIGRFAMs:   TIGR01364

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.52

Molecular weight: Translated: 39281; Mature: 39281

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: BINDING 41-41 BINDING 101-101 BINDING 152-152 BINDING 171-171 BINDING 194-194

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAYNFCAGPAALPTAVLEKAQQELLDWQGKGLSIMEMSHRSADYVAVAEKAEADLRKLM
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHH
NIPENYKVLFLQGGASLQFSAIPLNLLGKNNKADYIHTGIWSEKALKEAKRYGDINVVEA
CCCCCCEEEEEECCCCEEEEEEEEEEECCCCCCCEEEECCCHHHHHHHHHHCCCCEEEEE
GIKVDGKFAISEQSEWNLSDDAAYVHYADNETIGGLQFAGVPDVKAPLVCDFSSSILSAP
CEEECCEEEECCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCEEECCCHHHHHCC
LDVSKFGLIYAGAQKNIGPAGLTIVIIRDDLLDQAKAEIPSILKYADQAKNGSMVNTPST
CCHHHCCEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
YAWYLSGLVFEWLLEQGGVDAIHKVNLEKAQLLYGYIDSSDFYNNPIAIPNRSIMNVPFT
HHHHHHHHHHHHHHHHCCCCCCHHCCCHHHEEEEEEECCCCCCCCCCCCCCCCEEECCHH
LADEALEKQFLKEAEANHLLNLAGHRSVGGMRASIYNAVPLEGVQALIRFMDDFAKRNG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRAYNFCAGPAALPTAVLEKAQQELLDWQGKGLSIMEMSHRSADYVAVAEKAEADLRKLM
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHH
NIPENYKVLFLQGGASLQFSAIPLNLLGKNNKADYIHTGIWSEKALKEAKRYGDINVVEA
CCCCCCEEEEEECCCCEEEEEEEEEEECCCCCCCEEEECCCHHHHHHHHHHCCCCEEEEE
GIKVDGKFAISEQSEWNLSDDAAYVHYADNETIGGLQFAGVPDVKAPLVCDFSSSILSAP
CEEECCEEEECCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCEEECCCHHHHHCC
LDVSKFGLIYAGAQKNIGPAGLTIVIIRDDLLDQAKAEIPSILKYADQAKNGSMVNTPST
CCHHHCCEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
YAWYLSGLVFEWLLEQGGVDAIHKVNLEKAQLLYGYIDSSDFYNNPIAIPNRSIMNVPFT
HHHHHHHHHHHHHHHHCCCCCCHHCCCHHHEEEEEEECCCCCCCCCCCCCCCCEEECCHH
LADEALEKQFLKEAEANHLLNLAGHRSVGGMRASIYNAVPLEGVQALIRFMDDFAKRNG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA