Click here to switch to the map view.

The map label for this gene is cbl [H]

Identifier: 213158258

GI number: 213158258

Start: 3072852

End: 3073775

Strand: Direct

Name: cbl [H]

Synonym: AB57_2978

Alternate gene names: 213158258

Gene position: 3072852-3073775 (Clockwise)

Preceding gene: 213158257

Following gene: 213158260

Centisome position: 75.86

GC content: 37.77

Gene sequence:

>924_bases
ATGAACTTTCAACAATTAAGAATTATCCGAGAAACAGTACGCCAAAACTTTAATTTAACGGAAGCATCTGCCGCGTTATA
TACCTCTCAATCAGGTGTAAGTAAACATATTAAAGATTTAGAAGATGAATTAGGCGTACAACTTTTCGTCCGTAAAGGTA
AACGTCTGCTGGGTTTAACTGAACCCGGTCAATCACTCCTTAGCATTGTAGAACGCATGCTTGTAGATGCTGAAAATATT
AAACGTCTTGCCGATGACTTTAATAAAGTGGACGAAGGTACTTTAACGATTGCAACAACTCATACTCAAGCACGTTATGT
ATTACCACCAATCGTCAATCAATTTAAGAAACTATTTCCAAAAGTTCATTTGATTTTGCAACAAGCAAGTCCTGTCGAAA
TTGCAGAAATGCTTTTACAAGGTGAAGCTGATATTGGTATCGCGACAGAGTCTTTAACAACTGAAGAAAATTTAGCAAGT
ATTCCATACTATCAATGGCAGCACAGCATTATTACTCCTCAAGATCACCCACTTACACAGCTCGATAAAATTGATCTTGA
TGCTTTATCTGAGTACCCACTGATTACTTATCACGGCGGTTTTACAGGTCGTTCAAAGATCGATAAAGCATTTGAAGATG
CACAAATTGATGCCGATATTGTAATGTCTGCGCTTGATGCCGATGTTATCAAGACTTACGTTGAACTCGGCATGGGCGTC
GGAATTGTCAATGATGTCGCTTACGATGCAGAGCGTGACTATCGTTTAAAACAAATTAAAACTGATATCTTTGGTGTCAA
CACCACATGGATTGCTGTTCGCAAAGGCCATTTATTACGTGGTTATGGTTATGAGTTTATTTCTTTATGCTCACCTGATG
CTGACATTAAAGCATTGAAAAAAATTGCCTATCCAGATGAATAA

Upstream 100 bases:

>100_bases
TTCACCTATTTGCAGATCAAGTTGCTTAAGGAATTATTTGGTGAGGAGCCATCTCGCGGTATTTAAAGCCGTTCCTCACC
TCTTTTGAGGAAAAGTGTAA

Downstream 100 bases:

>100_bases
AATTTAAGGGAAAAATAAAAGAGCTACGTAAGTAGCTCTTTTATTTTTAAACATAAAAAAACGAGCCGAAGCTCGTTTTT
ATGCTTTATTACCAGAAGAA

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNFQQLRIIRETVRQNFNLTEASAALYTSQSGVSKHIKDLEDELGVQLFVRKGKRLLGLTEPGQSLLSIVERMLVDAENI
KRLADDFNKVDEGTLTIATTHTQARYVLPPIVNQFKKLFPKVHLILQQASPVEIAEMLLQGEADIGIATESLTTEENLAS
IPYYQWQHSIITPQDHPLTQLDKIDLDALSEYPLITYHGGFTGRSKIDKAFEDAQIDADIVMSALDADVIKTYVELGMGV
GIVNDVAYDAERDYRLKQIKTDIFGVNTTWIAVRKGHLLRGYGYEFISLCSPDADIKALKKIAYPDE

Sequences:

>Translated_307_residues
MNFQQLRIIRETVRQNFNLTEASAALYTSQSGVSKHIKDLEDELGVQLFVRKGKRLLGLTEPGQSLLSIVERMLVDAENI
KRLADDFNKVDEGTLTIATTHTQARYVLPPIVNQFKKLFPKVHLILQQASPVEIAEMLLQGEADIGIATESLTTEENLAS
IPYYQWQHSIITPQDHPLTQLDKIDLDALSEYPLITYHGGFTGRSKIDKAFEDAQIDADIVMSALDADVIKTYVELGMGV
GIVNDVAYDAERDYRLKQIKTDIFGVNTTWIAVRKGHLLRGYGYEFISLCSPDADIKALKKIAYPDE
>Mature_307_residues
MNFQQLRIIRETVRQNFNLTEASAALYTSQSGVSKHIKDLEDELGVQLFVRKGKRLLGLTEPGQSLLSIVERMLVDAENI
KRLADDFNKVDEGTLTIATTHTQARYVLPPIVNQFKKLFPKVHLILQQASPVEIAEMLLQGEADIGIATESLTTEENLAS
IPYYQWQHSIITPQDHPLTQLDKIDLDALSEYPLITYHGGFTGRSKIDKAFEDAQIDADIVMSALDADVIKTYVELGMGV
GIVNDVAYDAERDYRLKQIKTDIFGVNTTWIAVRKGHLLRGYGYEFISLCSPDADIKALKKIAYPDE

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=302, Percent_Identity=51.6556291390728, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1787530, Length=293, Percent_Identity=45.0511945392491, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI157672245, Length=225, Percent_Identity=31.5555555555556, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI2367136, Length=233, Percent_Identity=22.3175965665236, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=25.7627118644068, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790399, Length=253, Percent_Identity=24.5059288537549, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=28.1632653061224, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI145693105, Length=230, Percent_Identity=23.0434782608696, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789204, Length=230, Percent_Identity=26.5217391304348, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082132, Length=140, Percent_Identity=32.8571428571429, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790262, Length=281, Percent_Identity=24.9110320284698, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790208, Length=245, Percent_Identity=25.3061224489796, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788748, Length=253, Percent_Identity=25.296442687747, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34471; Mature: 34471

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRIIRETVRQNFNLTEASAALYTSQSGVSKHIKDLEDELGVQLFVRKGKRLLGLT
CCHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHCCCCEECCC
EPGQSLLSIVERMLVDAENIKRLADDFNKVDEGTLTIATTHTQARYVLPPIVNQFKKLFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCHHHHHHHHHHH
KVHLILQQASPVEIAEMLLQGEADIGIATESLTTEENLASIPYYQWQHSIITPQDHPLTQ
HHHHHHHCCCCHHHHHHHHCCCCCCCEECCCCCCHHHHHCCCCHHCCCCCCCCCCCCCCH
LDKIDLDALSEYPLITYHGGFTGRSKIDKAFEDAQIDADIVMSALDADVIKTYVELGMGV
HHHCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
GIVNDVAYDAERDYRLKQIKTDIFGVNTTWIAVRKGHLLRGYGYEFISLCSPDADIKALK
CHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEECCCHHHHHHCCCCHHHHHHH
KIAYPDE
HHCCCCC
>Mature Secondary Structure
MNFQQLRIIRETVRQNFNLTEASAALYTSQSGVSKHIKDLEDELGVQLFVRKGKRLLGLT
CCHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHCCCCEECCC
EPGQSLLSIVERMLVDAENIKRLADDFNKVDEGTLTIATTHTQARYVLPPIVNQFKKLFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCHHHHHHHHHHH
KVHLILQQASPVEIAEMLLQGEADIGIATESLTTEENLASIPYYQWQHSIITPQDHPLTQ
HHHHHHHCCCCHHHHHHHHCCCCCCCEECCCCCCHHHHHCCCCHHCCCCCCCCCCCCCCH
LDKIDLDALSEYPLITYHGGFTGRSKIDKAFEDAQIDADIVMSALDADVIKTYVELGMGV
HHHCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
GIVNDVAYDAERDYRLKQIKTDIFGVNTTWIAVRKGHLLRGYGYEFISLCSPDADIKALK
CHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEECCCHHHHHHCCCCHHHHHHH
KIAYPDE
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]