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The map label for this gene is degP [H]

Identifier: 213158247

GI number: 213158247

Start: 3061652

End: 3063028

Strand: Reverse

Name: degP [H]

Synonym: AB57_2966

Alternate gene names: 213158247

Gene position: 3063028-3061652 (Counterclockwise)

Preceding gene: 213158249

Following gene: 213158246

Centisome position: 75.62

GC content: 40.74

Gene sequence:

>1377_bases
ATGAAATCTCGCTATTTACAACAAGGAATGTATGCAGCGGTATTTACAGTTGCTGCTGTTCAAGCAAATGCTGCTGTTGA
TTTTTCAAACCTCGTTGAACAAGTTAGTCCGGCTGTGGTGAGTGTAAACGTTGTAAAAAAAATGACTCAGGATGAACTGT
TACAACAGCAAGTTCCTGAAATTTTAAAACGTTTCTTTGGTAATCAGGTCATCATTCCACAGCAACAAGGTCCTCAAGAG
AAAACTGCATATGGTAGTGCGTTCTTTATTAGTAAAGATGGTTATTTACTTACGAACCACCATGTAATTGAAAACGCTTC
CCGCATCAGTATTACTTTAAATGACCGTCGTGAAATTGATGCAACAGTGGTCGGTAGTGATGAGCGGACAGACGTTGCAT
TATTAAAGGTAAACGGAACTAACTATCCTGCTTTACGCGTAGGAAATGTTGATCGTTTACGTGTAGGAGAGCCGGTTTTA
GCAATTGGTTCACCATTTGGTTTTGATTATTCAGCTTCGGCAGGTATTGTCAGCGCTAAATCACGTAACATGAGCGGTGA
AACCTCTGTACCATTTATTCAAACCGATGTGGCGTTGAACCCTGGTAACTCAGGTGGTCCATTGTTTAACCAAAATGGTG
AAGTTGTCGGGGTGAACTCACGTATCTTTAGTGGTACGGGGGGGTATATGGGCTTATCTTTCTCTATTCCAATTGATGTT
GCGATGGATGTAGCTGAACAGCTTAAAACGAAAGGGAAAGTGACTCGTTCATACCTAGGCGTTATGATGCAAGATATTGA
CCGTAACCTTGCAGATGCCTATAAATTGCCTAAACCGGAAGGTGCTCTGATTACTCAGGTTTCTCCAAATTCACCTGCTC
AAAAAGCAGGGCTTAGAGCTGGCGATGTTATTCTAAAATTAAATGGTGCTTCTGTACTGCGTACTAGTGATTTGCTTTAT
GCATTAAATAAAGTACAACCAAACCAAACTGTTCAGTTTGAAGTTTTACGTGATGATAAAACCCGAAATATCTCGGCAAC
ACTAGCAACTGCACCTGATGAAACACCGGCTACCGGTAATCAAGCCTCTGCTTCTAAAGGTCCAGTATTGGGAATGAGTA
TTCGTGATCTCGCTGTGCCAGAGAAAAATGCTTTAGGTATAAAAGGCGGTATTTATGTACAAGATGTTCGCCGTGGTGGA
TTAGCATCATTGTCAAATATCATTCCAGGCGATGTGATTATTCAGGTTAACAATACTCAGATTTTGAATAGTCAGGATTT
TGCAAAAGTTGTTTCTAATTTGCCAAAAAATACAGTTGCGCGAGTTGGGATCATTCGTCAAGGACAACGAGCAATGCTTG
GTTTACGTATTCAGTAA

Upstream 100 bases:

>100_bases
GATGCCTTACAAATAAACATATTGTTACGCACAATTCCAAAGCATTGTGATACAAAAGTTTTATTCTTATTCTTGTAGAC
CAATTGTGGGTGAGCACCGA

Downstream 100 bases:

>100_bases
AATATTATAAAAATGAACCACCCTGAAAATGGGTGGTTTTTTATTATTTGTATTCGGCATAATGTTCGATCTAGCGAATT
AAATTTTAGCTTTGAGTTTA

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKSRYLQQGMYAAVFTVAAVQANAAVDFSNLVEQVSPAVVSVNVVKKMTQDELLQQQVPEILKRFFGNQVIIPQQQGPQE
KTAYGSAFFISKDGYLLTNHHVIENASRISITLNDRREIDATVVGSDERTDVALLKVNGTNYPALRVGNVDRLRVGEPVL
AIGSPFGFDYSASAGIVSAKSRNMSGETSVPFIQTDVALNPGNSGGPLFNQNGEVVGVNSRIFSGTGGYMGLSFSIPIDV
AMDVAEQLKTKGKVTRSYLGVMMQDIDRNLADAYKLPKPEGALITQVSPNSPAQKAGLRAGDVILKLNGASVLRTSDLLY
ALNKVQPNQTVQFEVLRDDKTRNISATLATAPDETPATGNQASASKGPVLGMSIRDLAVPEKNALGIKGGIYVQDVRRGG
LASLSNIIPGDVIIQVNNTQILNSQDFAKVVSNLPKNTVARVGIIRQGQRAMLGLRIQ

Sequences:

>Translated_458_residues
MKSRYLQQGMYAAVFTVAAVQANAAVDFSNLVEQVSPAVVSVNVVKKMTQDELLQQQVPEILKRFFGNQVIIPQQQGPQE
KTAYGSAFFISKDGYLLTNHHVIENASRISITLNDRREIDATVVGSDERTDVALLKVNGTNYPALRVGNVDRLRVGEPVL
AIGSPFGFDYSASAGIVSAKSRNMSGETSVPFIQTDVALNPGNSGGPLFNQNGEVVGVNSRIFSGTGGYMGLSFSIPIDV
AMDVAEQLKTKGKVTRSYLGVMMQDIDRNLADAYKLPKPEGALITQVSPNSPAQKAGLRAGDVILKLNGASVLRTSDLLY
ALNKVQPNQTVQFEVLRDDKTRNISATLATAPDETPATGNQASASKGPVLGMSIRDLAVPEKNALGIKGGIYVQDVRRGG
LASLSNIIPGDVIIQVNNTQILNSQDFAKVVSNLPKNTVARVGIIRQGQRAMLGLRIQ
>Mature_458_residues
MKSRYLQQGMYAAVFTVAAVQANAAVDFSNLVEQVSPAVVSVNVVKKMTQDELLQQQVPEILKRFFGNQVIIPQQQGPQE
KTAYGSAFFISKDGYLLTNHHVIENASRISITLNDRREIDATVVGSDERTDVALLKVNGTNYPALRVGNVDRLRVGEPVL
AIGSPFGFDYSASAGIVSAKSRNMSGETSVPFIQTDVALNPGNSGGPLFNQNGEVVGVNSRIFSGTGGYMGLSFSIPIDV
AMDVAEQLKTKGKVTRSYLGVMMQDIDRNLADAYKLPKPEGALITQVSPNSPAQKAGLRAGDVILKLNGASVLRTSDLLY
ALNKVQPNQTVQFEVLRDDKTRNISATLATAPDETPATGNQASASKGPVLGMSIRDLAVPEKNALGIKGGIYVQDVRRGG
LASLSNIIPGDVIIQVNNTQILNSQDFAKVVSNLPKNTVARVGIIRQGQRAMLGLRIQ

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=307, Percent_Identity=32.2475570032573, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI24308541, Length=323, Percent_Identity=32.1981424148607, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI22129776, Length=319, Percent_Identity=29.7805642633229, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI7019477, Length=333, Percent_Identity=32.1321321321321, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1789629, Length=431, Percent_Identity=34.8027842227378, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1786356, Length=445, Percent_Identity=33.4831460674157, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1789630, Length=287, Percent_Identity=33.1010452961672, Blast_Score=155, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24646839, Length=286, Percent_Identity=32.1678321678322, Blast_Score=135, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 49067; Mature: 49067

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRYLQQGMYAAVFTVAAVQANAAVDFSNLVEQVSPAVVSVNVVKKMTQDELLQQQVPE
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
ILKRFFGNQVIIPQQQGPQEKTAYGSAFFISKDGYLLTNHHVIENASRISITLNDRREID
HHHHHCCCEEEEECCCCCCCHHCCCCEEEEECCCEEEECCCEECCCCEEEEEECCCCCEE
ATVVGSDERTDVALLKVNGTNYPALRVGNVDRLRVGEPVLAIGSPFGFDYSASAGIVSAK
EEEECCCCCCEEEEEEECCCCCCEEEECCCCEEECCCCEEEECCCCCCCCCCCCCEEEEC
SRNMSGETSVPFIQTDVALNPGNSGGPLFNQNGEVVGVNSRIFSGTGGYMGLSFSIPIDV
CCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEECCEEEECCCCEEEEEEECCHHH
AMDVAEQLKTKGKVTRSYLGVMMQDIDRNLADAYKLPKPEGALITQVSPNSPAQKAGLRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCCC
GDVILKLNGASVLRTSDLLYALNKVQPNQTVQFEVLRDDKTRNISATLATAPDETPATGN
CCEEEEECCCCEEEHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCC
QASASKGPVLGMSIRDLAVPEKNALGIKGGIYVQDVRRGGLASLSNIIPGDVIIQVNNTQ
CCCCCCCCEEEEEHHHHCCCCCCCCCCCCCEEEEEHHCCCHHHHHHCCCCCEEEEECCCE
ILNSQDFAKVVSNLPKNTVARVGIIRQGQRAMLGLRIQ
EECCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MKSRYLQQGMYAAVFTVAAVQANAAVDFSNLVEQVSPAVVSVNVVKKMTQDELLQQQVPE
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
ILKRFFGNQVIIPQQQGPQEKTAYGSAFFISKDGYLLTNHHVIENASRISITLNDRREID
HHHHHCCCEEEEECCCCCCCHHCCCCEEEEECCCEEEECCCEECCCCEEEEEECCCCCEE
ATVVGSDERTDVALLKVNGTNYPALRVGNVDRLRVGEPVLAIGSPFGFDYSASAGIVSAK
EEEECCCCCCEEEEEEECCCCCCEEEECCCCEEECCCCEEEECCCCCCCCCCCCCEEEEC
SRNMSGETSVPFIQTDVALNPGNSGGPLFNQNGEVVGVNSRIFSGTGGYMGLSFSIPIDV
CCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEECCEEEECCCCEEEEEEECCHHH
AMDVAEQLKTKGKVTRSYLGVMMQDIDRNLADAYKLPKPEGALITQVSPNSPAQKAGLRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCCC
GDVILKLNGASVLRTSDLLYALNKVQPNQTVQFEVLRDDKTRNISATLATAPDETPATGN
CCEEEEECCCCEEEHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCC
QASASKGPVLGMSIRDLAVPEKNALGIKGGIYVQDVRRGGLASLSNIIPGDVIIQVNNTQ
CCCCCCCCEEEEEHHHHCCCCCCCCCCCCCEEEEEHHCCCHHHHHHCCCCCEEEEECCCE
ILNSQDFAKVVSNLPKNTVARVGIIRQGQRAMLGLRIQ
EECCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]