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The map label for this gene is obgE

Identifier: 213158222

GI number: 213158222

Start: 3038060

End: 3039280

Strand: Reverse

Name: obgE

Synonym: AB57_2941

Alternate gene names: 213158222

Gene position: 3039280-3038060 (Counterclockwise)

Preceding gene: 213158223

Following gene: 213158221

Centisome position: 75.03

GC content: 44.31

Gene sequence:

>1221_bases
ATGCGCTTTGTTGATGAAGCAGTCATTACCGTAGAGGCTGGCGACGGTGGCAATGGCGTAGCCAGTTTTCGCCGTGAAAA
ATTTGTACCATTTGGTGGCCCAGATGGTGGTGATGGCGGACGTGGTGGAAGTATCTATATTCAAGCAGATGATGATACAA
GTACCCTAGTCGATTACCGTTACACCCGTAAATTCCGCGCTGAGCGTGGTAAAAACGGTGCAGGTGCTAACTGTACCGGA
CGTGGTGGTGAAGATGTGGTTTTAAAAGTACCCGTTGGTACAACAATTGTTGATACAGATTCAGGCGATATTATTGGCGA
TCTGGTAGAAGACGGCCAAAGAGTCATGGTTGCAAGCGGTGGTGAAGGTGGTTTAGGAAATACTCACTTTAAATCATCAA
CCAACCGTGCTCCACGTAAATGTACGACAGGTACAAAAGGTGAGTTCCGTGAAATTCGCCTTGAGTTGAAAGTATTGGCA
GATGTTGGCTTATTAGGTATGCCAAATGCTGGTAAATCAACATTTATTCGTGCAGTAAGTGCCGCGAAACCAAAAGTAGC
AGATTATCCATTTACCACTATGGTTCCTAACCTAGGTGTAGTAGATGCTGACCGTCACCGCTCGTTTGTGATGGCAGATA
TTCCGGGACTTATTGAAGGTGCAGCAGAAGGTGCAGGTTTAGGTATTCGTTTCCTTAAGCATTTAGCACGTACACGTATT
CTTTTGCACATTATTGATGTACAACCAATTGATGGTTCAGACCCGGCCCATAATGCTAAAGCAATTATGAATGAACTTGC
CAAGTTTTCTCCTACTTTGGCGAAGTTACCAATTGTATTAGTACTCAATAAACTTGATCAGATTGCTGAAGAAAGCCGTG
AAGAATGGTGTCAGCATATTCTAGATGAGTTGCAATGGACAGGTCCTGTCTTTAAGACCTCGGGTTTACTCGAAGAAGGA
ACCAAAGAAGTTGTTTATTACCTCATGGATCAGATTGAACAACAACGTGAACGTGAAGTTGAAGATCCTGAGTACGCAGC
AGAAGTAAGAGCATTCCGTGAACAGCTTGAAGCTGAAACACGTGAACAGACCATTGCAGCGAAGGAAGCATACCGTGCTA
TGCGTAAGGCACAACGCCTTGAAAGCATGATGGACGATGATGATGACTTCGATGACGATGAAGACGATGGTGATGTAGAA
AGCATCTACGTTCGTGATTAA

Upstream 100 bases:

>100_bases
AATAAGCAGCAGGAAAGTAGAATTCTCTCGATTTTCTATTCGAGAATTTTCTGAAAATATGGCAGAATAGGCGGTTTTAG
AGTTTTTAGAGGATTGGCAA

Downstream 100 bases:

>100_bases
AAAACCGAGGAAAACATGATAGAAGTGGTCGATGGGCAACGTAAGCTCAGTGAGTGTAAACGAATCGTTGTTAAAATCGG
ATCATCTTTACTCACGGCAA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRFVDEAVITVEAGDGGNGVASFRREKFVPFGGPDGGDGGRGGSIYIQADDDTSTLVDYRYTRKFRAERGKNGAGANCTG
RGGEDVVLKVPVGTTIVDTDSGDIIGDLVEDGQRVMVASGGEGGLGNTHFKSSTNRAPRKCTTGTKGEFREIRLELKVLA
DVGLLGMPNAGKSTFIRAVSAAKPKVADYPFTTMVPNLGVVDADRHRSFVMADIPGLIEGAAEGAGLGIRFLKHLARTRI
LLHIIDVQPIDGSDPAHNAKAIMNELAKFSPTLAKLPIVLVLNKLDQIAEESREEWCQHILDELQWTGPVFKTSGLLEEG
TKEVVYYLMDQIEQQREREVEDPEYAAEVRAFREQLEAETREQTIAAKEAYRAMRKAQRLESMMDDDDDFDDDEDDGDVE
SIYVRD

Sequences:

>Translated_406_residues
MRFVDEAVITVEAGDGGNGVASFRREKFVPFGGPDGGDGGRGGSIYIQADDDTSTLVDYRYTRKFRAERGKNGAGANCTG
RGGEDVVLKVPVGTTIVDTDSGDIIGDLVEDGQRVMVASGGEGGLGNTHFKSSTNRAPRKCTTGTKGEFREIRLELKVLA
DVGLLGMPNAGKSTFIRAVSAAKPKVADYPFTTMVPNLGVVDADRHRSFVMADIPGLIEGAAEGAGLGIRFLKHLARTRI
LLHIIDVQPIDGSDPAHNAKAIMNELAKFSPTLAKLPIVLVLNKLDQIAEESREEWCQHILDELQWTGPVFKTSGLLEEG
TKEVVYYLMDQIEQQREREVEDPEYAAEVRAFREQLEAETREQTIAAKEAYRAMRKAQRLESMMDDDDDFDDDEDDGDVE
SIYVRD
>Mature_406_residues
MRFVDEAVITVEAGDGGNGVASFRREKFVPFGGPDGGDGGRGGSIYIQADDDTSTLVDYRYTRKFRAERGKNGAGANCTG
RGGEDVVLKVPVGTTIVDTDSGDIIGDLVEDGQRVMVASGGEGGLGNTHFKSSTNRAPRKCTTGTKGEFREIRLELKVLA
DVGLLGMPNAGKSTFIRAVSAAKPKVADYPFTTMVPNLGVVDADRHRSFVMADIPGLIEGAAEGAGLGIRFLKHLARTRI
LLHIIDVQPIDGSDPAHNAKAIMNELAKFSPTLAKLPIVLVLNKLDQIAEESREEWCQHILDELQWTGPVFKTSGLLEEG
TKEVVYYLMDQIEQQREREVEDPEYAAEVRAFREQLEAETREQTIAAKEAYRAMRKAQRLESMMDDDDDFDDDEDDGDVE
SIYVRD

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=285, Percent_Identity=40.7017543859649, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI111955139, Length=234, Percent_Identity=41.025641025641, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI111955063, Length=126, Percent_Identity=40.4761904761905, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI1789574, Length=357, Percent_Identity=57.703081232493, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1787454, Length=129, Percent_Identity=31.7829457364341, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=332, Percent_Identity=37.3493975903614, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=338, Percent_Identity=28.9940828402367, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.15625, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=168, Percent_Identity=36.9047619047619, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319281, Length=128, Percent_Identity=35.15625, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129375, Length=344, Percent_Identity=37.5, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24585318, Length=294, Percent_Identity=38.0952380952381, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=32.8125, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=32.8125, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=32.8125, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_ACIB3 (B7GYV1)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002324860.1
- ProteinModelPortal:   B7GYV1
- SMR:   B7GYV1
- GeneID:   7057792
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_000948
- HOGENOM:   HBG716038
- OMA:   YIQADEN
- ProtClustDB:   PRK12298
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 44462; Mature: 44462

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVDEAVITVEAGDGGNGVASFRREKFVPFGGPDGGDGGRGGSIYIQADDDTSTLVDYR
CCCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHH
YTRKFRAERGKNGAGANCTGRGGEDVVLKVPVGTTIVDTDSGDIIGDLVEDGQRVMVASG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHCCCEEEEEEC
GEGGLGNTHFKSSTNRAPRKCTTGTKGEFREIRLELKVLADVGLLGMPNAGKSTFIRAVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTMVPNLGVVDADRHRSFVMADIPGLIEGAAEGAGLGIRFLKHLARTRI
HCCCCCCCCCHHHHCCCCCCEECCCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHH
LLHIIDVQPIDGSDPAHNAKAIMNELAKFSPTLAKLPIVLVLNKLDQIAEESREEWCQHI
EEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDELQWTGPVFKTSGLLEEGTKEVVYYLMDQIEQQREREVEDPEYAAEVRAFREQLEAET
HHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
REQTIAAKEAYRAMRKAQRLESMMDDDDDFDDDEDDGDVESIYVRD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MRFVDEAVITVEAGDGGNGVASFRREKFVPFGGPDGGDGGRGGSIYIQADDDTSTLVDYR
CCCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHH
YTRKFRAERGKNGAGANCTGRGGEDVVLKVPVGTTIVDTDSGDIIGDLVEDGQRVMVASG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHCCCEEEEEEC
GEGGLGNTHFKSSTNRAPRKCTTGTKGEFREIRLELKVLADVGLLGMPNAGKSTFIRAVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTMVPNLGVVDADRHRSFVMADIPGLIEGAAEGAGLGIRFLKHLARTRI
HCCCCCCCCCHHHHCCCCCCEECCCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHH
LLHIIDVQPIDGSDPAHNAKAIMNELAKFSPTLAKLPIVLVLNKLDQIAEESREEWCQHI
EEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDELQWTGPVFKTSGLLEEGTKEVVYYLMDQIEQQREREVEDPEYAAEVRAFREQLEAET
HHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
REQTIAAKEAYRAMRKAQRLESMMDDDDDFDDDEDDGDVESIYVRD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA