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The map label for this gene is fabR [H]

Identifier: 213158173

GI number: 213158173

Start: 2979650

End: 2980345

Strand: Direct

Name: fabR [H]

Synonym: AB57_2890

Alternate gene names: 213158173

Gene position: 2979650-2980345 (Clockwise)

Preceding gene: 213158170

Following gene: 213158174

Centisome position: 73.56

GC content: 39.94

Gene sequence:

>696_bases
ATGACCCAAACCTCACTTTCTCAGAGCCCAAATGACACAACCTCATCACAAGATGTCATTGAAATAAAAACAGTAACGCG
TTCTGTTGGAAGAAAAGCGACGATTACGAAAGAAGAACTTTTTCAGGCAGCTCTTAACCTGATTGGTCCACAAAAAAGTA
TTGCCTCACTCAGTTTACGTGAAGTTGCAAGAGAAGCTGGTATTGCCCCAAACAGTTTTTATCGTCACTTTAAAGACATT
GATGAGTTAGCTATTTCACTCATTGACCGTGCCGGTATCGTTTTACGTAAAATTATTCGTCAAGCACGCCTTCGTGCATC
TTTGCAAGACAGCATTATTCGCAGTTCTGTAGAAATTTTTCTGCAACAGCTGGATGCTGATGAAGGCAATTTAAGTTTAT
TGTTGCGAGAAGGTTTTACAGGTTCCGCTTCTTATAAAGCTGCTGTAGATCGACAGCTCAACTTCTTTCAGCAAGAGCTA
CAAGAAGATTTAATTCGCTTAGAACGCCTCAATAACAATCATCTATACCATCCTGAACTTGTTGCAAAAGCAATTACACA
ACTTGTTTTTCACATGGGTGCCAAAGTGATTGACCTTCCTATTGATCAGCGTGCGGAAGTCGCAGAACAAACAATGATTA
TGATCAGAATGATTTTAGAAGGTGCCCGTCATCTAGACGAAGCAAAAATAAGATAG

Upstream 100 bases:

>100_bases
TGTATATATATTTGTATATACACTCGTACTTTTAATTACAATTTCACAAGTTCCCTGTCTAACGCTATAATCCAGACAGT
TTAAGAATATATTGAAAAAC

Downstream 100 bases:

>100_bases
ATTCCACATAAAATGGTTTGTGATTTTACAAGCCATTTTTTATACACCTGTGCCTGCTGATTAATAAAAATATAAACCAT
AGATTGAAGCAGCTTAGATG

Product: transcriptional regulator, TetR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTQTSLSQSPNDTTSSQDVIEIKTVTRSVGRKATITKEELFQAALNLIGPQKSIASLSLREVAREAGIAPNSFYRHFKDI
DELAISLIDRAGIVLRKIIRQARLRASLQDSIIRSSVEIFLQQLDADEGNLSLLLREGFTGSASYKAAVDRQLNFFQQEL
QEDLIRLERLNNNHLYHPELVAKAITQLVFHMGAKVIDLPIDQRAEVAEQTMIMIRMILEGARHLDEAKIR

Sequences:

>Translated_231_residues
MTQTSLSQSPNDTTSSQDVIEIKTVTRSVGRKATITKEELFQAALNLIGPQKSIASLSLREVAREAGIAPNSFYRHFKDI
DELAISLIDRAGIVLRKIIRQARLRASLQDSIIRSSVEIFLQQLDADEGNLSLLLREGFTGSASYKAAVDRQLNFFQQEL
QEDLIRLERLNNNHLYHPELVAKAITQLVFHMGAKVIDLPIDQRAEVAEQTMIMIRMILEGARHLDEAKIR
>Mature_230_residues
TQTSLSQSPNDTTSSQDVIEIKTVTRSVGRKATITKEELFQAALNLIGPQKSIASLSLREVAREAGIAPNSFYRHFKDID
ELAISLIDRAGIVLRKIIRQARLRASLQDSIIRSSVEIFLQQLDADEGNLSLLLREGFTGSASYKAAVDRQLNFFQQELQ
EDLIRLERLNNNHLYHPELVAKAITQLVFHMGAKVIDLPIDQRAEVAEQTMIMIRMILEGARHLDEAKIR

Specific function: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, fabR directly influences the physical properties of the membrane bilayer [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693209, Length=192, Percent_Identity=42.1875, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 26034; Mature: 25903

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTSLSQSPNDTTSSQDVIEIKTVTRSVGRKATITKEELFQAALNLIGPQKSIASLSLR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
EVAREAGIAPNSFYRHFKDIDELAISLIDRAGIVLRKIIRQARLRASLQDSIIRSSVEIF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQQLDADEGNLSLLLREGFTGSASYKAAVDRQLNFFQQELQEDLIRLERLNNNHLYHPEL
HHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VAKAITQLVFHMGAKVIDLPIDQRAEVAEQTMIMIRMILEGARHLDEAKIR
HHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQTSLSQSPNDTTSSQDVIEIKTVTRSVGRKATITKEELFQAALNLIGPQKSIASLSLR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
EVAREAGIAPNSFYRHFKDIDELAISLIDRAGIVLRKIIRQARLRASLQDSIIRSSVEIF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQQLDADEGNLSLLLREGFTGSASYKAAVDRQLNFFQQELQEDLIRLERLNNNHLYHPEL
HHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VAKAITQLVFHMGAKVIDLPIDQRAEVAEQTMIMIRMILEGARHLDEAKIR
HHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA