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The map label for this gene is desA3 [H]

Identifier: 213158171

GI number: 213158171

Start: 2977330

End: 2978424

Strand: Reverse

Name: desA3 [H]

Synonym: AB57_2885

Alternate gene names: 213158171

Gene position: 2978424-2977330 (Counterclockwise)

Preceding gene: 213158172

Following gene: 213158169

Centisome position: 73.53

GC content: 38.36

Gene sequence:

>1095_bases
ATGAATATGCCAGTGAAAGTCGAATATTTTAAAAATCCTAAAAATCGAGATTTGACTCCAGCAGAACTTGAAGCATTTGC
AAAAGAGCTTGATCAGATCAAACAAGAAGTATTGGATGATTTGGGTGAAAAAGACGCTAAATATATCCGCCGTGTCTATG
CTGCTATTCGTTATAGTAGCTTTTTAGGCCGAGCTTGTTTATTTGCAGGTTGGTTCCCGCCAGCGTGGATTTTAGGTACA
GGTTTATTAGGTTTCTCTAAAATTATGGAGAACATGGAGCTCGGCCATAATGTTATGCACGGTCAATATGACTGGATGAA
TGACCCGAAATTTAATGGTCAAACTTATGAATGGGATACTGTAGGTACCTCTGACAACTGGCGTCAAACCCACAACTATA
AACATCATACTTATACCAATATTAAAGGTATTGATGATGACATTGGTTATGGCTTACTTCGCTTATTCCCTGAACAACGT
TGGAAGCCAGGGTTCTTATTGCAGCCTATTTACAGTATTCCATTTTGCTTATTGTTCCAGTGGGGTGTAGCAATTCAGAA
TCTTGAAATTGGGCGTGTACTTTACAAGCGTAAGACTAAGGCACAATTTTTAGAAGAGTTAAAACCAGTTAATAAAAAGA
TTGGCAAGCAACTCTTTAAAGATTATGTTTTCTTCCCACTTATTGCAGGGCCGGCAGCATTACCAGTATTTACAGGTAAC
TTGGTCGCAAATGGTCTTCGTAATATCTGGACCTTTAGTATTATTTTCTGTGGACATTTCACGAAAGATGCAGAAGTGTT
CCCAAAATCTGTTTTACAAGAAGAAAGCCGTGGACACTGGTATATGCGCCAAATTCGTGGTTCTTCTAACTTAACAGGTT
CAGAAGCATTCCATATTTTGTCTGGTCACTTAAGTCATCAAATTGAACATCACTTATTCCCAGATATTCCTGCTCGTCGT
TATCGCCAAATGGCTCCAAAAGTTGAGGCAGTTTGTAAGAAATATGGCTTGAACTATAACAATGCCAGCTTTGTTAAGCA
GTTTGGACAAGTGGTTGGACGTATTGTGAAATATGCGTTCCCATTTAAAAAATAA

Upstream 100 bases:

>100_bases
ACTAAACGGTAGCCAAAATACGGAACCAAGCCAATTACTTAAAATTTGTGTGAACTCAGCACAATCCGATCTAGTTATTG
ATCTTTAAGAGAGAACTCTT

Downstream 100 bases:

>100_bases
GATAAAAGAGCCCTGAGAATTCAGGGCTTTTTTTTATTTCTTTTTAGAAATCCACATGGTAATTGTGGCATGAAATACTT
TATCTTTGTGAGTGTCGTAA

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(9)-desaturase; Stearoyl-CoA desaturase [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MNMPVKVEYFKNPKNRDLTPAELEAFAKELDQIKQEVLDDLGEKDAKYIRRVYAAIRYSSFLGRACLFAGWFPPAWILGT
GLLGFSKIMENMELGHNVMHGQYDWMNDPKFNGQTYEWDTVGTSDNWRQTHNYKHHTYTNIKGIDDDIGYGLLRLFPEQR
WKPGFLLQPIYSIPFCLLFQWGVAIQNLEIGRVLYKRKTKAQFLEELKPVNKKIGKQLFKDYVFFPLIAGPAALPVFTGN
LVANGLRNIWTFSIIFCGHFTKDAEVFPKSVLQEESRGHWYMRQIRGSSNLTGSEAFHILSGHLSHQIEHHLFPDIPARR
YRQMAPKVEAVCKKYGLNYNNASFVKQFGQVVGRIVKYAFPFKK

Sequences:

>Translated_364_residues
MNMPVKVEYFKNPKNRDLTPAELEAFAKELDQIKQEVLDDLGEKDAKYIRRVYAAIRYSSFLGRACLFAGWFPPAWILGT
GLLGFSKIMENMELGHNVMHGQYDWMNDPKFNGQTYEWDTVGTSDNWRQTHNYKHHTYTNIKGIDDDIGYGLLRLFPEQR
WKPGFLLQPIYSIPFCLLFQWGVAIQNLEIGRVLYKRKTKAQFLEELKPVNKKIGKQLFKDYVFFPLIAGPAALPVFTGN
LVANGLRNIWTFSIIFCGHFTKDAEVFPKSVLQEESRGHWYMRQIRGSSNLTGSEAFHILSGHLSHQIEHHLFPDIPARR
YRQMAPKVEAVCKKYGLNYNNASFVKQFGQVVGRIVKYAFPFKK
>Mature_364_residues
MNMPVKVEYFKNPKNRDLTPAELEAFAKELDQIKQEVLDDLGEKDAKYIRRVYAAIRYSSFLGRACLFAGWFPPAWILGT
GLLGFSKIMENMELGHNVMHGQYDWMNDPKFNGQTYEWDTVGTSDNWRQTHNYKHHTYTNIKGIDDDIGYGLLRLFPEQR
WKPGFLLQPIYSIPFCLLFQWGVAIQNLEIGRVLYKRKTKAQFLEELKPVNKKIGKQLFKDYVFFPLIAGPAALPVFTGN
LVANGLRNIWTFSIIFCGHFTKDAEVFPKSVLQEESRGHWYMRQIRGSSNLTGSEAFHILSGHLSHQIEHHLFPDIPARR
YRQMAPKVEAVCKKYGLNYNNASFVKQFGQVVGRIVKYAFPFKK

Specific function: Desaturates stearoyl-CoA to form oleoyl-CoA [H]

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Probable). Note=Has been shown to be membrane-associated but no reliable trans-membrane regions are predicted by bioinformatics tools [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Homo sapiens, GI13375616, Length=297, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: NA

Molecular weight: Translated: 42203; Mature: 42203

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMPVKVEYFKNPKNRDLTPAELEAFAKELDQIKQEVLDDLGEKDAKYIRRVYAAIRYSS
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FLGRACLFAGWFPPAWILGTGLLGFSKIMENMELGHNVMHGQYDWMNDPKFNGQTYEWDT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCEEEECC
VGTSDNWRQTHNYKHHTYTNIKGIDDDIGYGLLRLFPEQRWKPGFLLQPIYSIPFCLLFQ
CCCCCCCHHHCCCCCCEECCCCCCCCHHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHHH
WGVAIQNLEIGRVLYKRKTKAQFLEELKPVNKKIGKQLFKDYVFFPLIAGPAALPVFTGN
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LVANGLRNIWTFSIIFCGHFTKDAEVFPKSVLQEESRGHWYMRQIRGSSNLTGSEAFHIL
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHH
SGHLSHQIEHHLFPDIPARRYRQMAPKVEAVCKKYGLNYNNASFVKQFGQVVGRIVKYAF
HHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
PFKK
CCCC
>Mature Secondary Structure
MNMPVKVEYFKNPKNRDLTPAELEAFAKELDQIKQEVLDDLGEKDAKYIRRVYAAIRYSS
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FLGRACLFAGWFPPAWILGTGLLGFSKIMENMELGHNVMHGQYDWMNDPKFNGQTYEWDT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCEEEECC
VGTSDNWRQTHNYKHHTYTNIKGIDDDIGYGLLRLFPEQRWKPGFLLQPIYSIPFCLLFQ
CCCCCCCHHHCCCCCCEECCCCCCCCHHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHHH
WGVAIQNLEIGRVLYKRKTKAQFLEELKPVNKKIGKQLFKDYVFFPLIAGPAALPVFTGN
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LVANGLRNIWTFSIIFCGHFTKDAEVFPKSVLQEESRGHWYMRQIRGSSNLTGSEAFHIL
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHH
SGHLSHQIEHHLFPDIPARRYRQMAPKVEAVCKKYGLNYNNASFVKQFGQVVGRIVKYAF
HHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
PFKK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]