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The map label for this gene is aaeR [H]

Identifier: 213158144

GI number: 213158144

Start: 2947041

End: 2947970

Strand: Reverse

Name: aaeR [H]

Synonym: AB57_2858

Alternate gene names: 213158144

Gene position: 2947970-2947041 (Counterclockwise)

Preceding gene: 213158145

Following gene: 213158142

Centisome position: 72.78

GC content: 40.32

Gene sequence:

>930_bases
ATGTTAGATCAGCTTCGTGCGATGGGTGTTTTTGCTTGTGTGGTTGAAAAAAGTTCATTTAGTGGTGCGGCACGTGAATT
AGGCATTACAACAAGTGCTGTAAGTCAGCAAATCCGTTCTCTTGAAAATGAAATGGATGTAATTTTATTACATCGTTCTA
CGCGAAAACTTAGTTTGACTGAGGCAGGGCAGGCTTTTTTCTCAAGTTGCCAAGAAATGTTGGCAGCAGCAGAAAGAGGC
AAAATCAGAATCAATGAATTGCGAGATGATTTGATTGGTGACTTGCGTATTGCAACTACCCCTGATTTAGCGGTTCAGCA
CATTATTCCTGCTTTATCTCACTGGATGTCTGCCCATCGTGGTCTATCTGTTCATTTTGAAGTGGGGCATCGATATATCG
ATTTAATCGAAGAGCGAATTGATATTGCAGTGCGCATGAGTTCTACAGCGGTAGAAGAGAGCGACTCTGTTATTCCTATG
GCTTTTGTCGATCAGATTTTGGTAGCCTCTCCCAGCTATCTCAATCAAACAAGCCCAATCTTGCATCCAAATGATTTAAA
CAACCATGAGTTGCTTTCTATCAATGCAATGAATGATTCACGTAGTTTTAATTTTCAGCACGCTAAAACTGGTGAAAAAT
TAAATATCGAGATGGCAAGCCGTTTGCAAAGTAATAATTTACAAGTGGCTAAAGCGCTATGCCAGCAAGGGCATGGAATT
GCCAGAATTTTATATTTAGATGCTCAAAAAGAACTGAAGAATGGTTCTTTAATTGAAATCCTTCCAGATTGGAAACTCCC
AGCTTTCACTTTATATGCAGAGATTGCAAAACACGATCAACAGCCAATGAAAATTCAACGTTGTGTCGAAGCGCTTAAGC
AATACTTCAGCCAGTTGGCTGGCGGAAGAGCAATGCAGATTGTTCGTTAA

Upstream 100 bases:

>100_bases
TAATGCATTAAATATAGGTTTCCTCGTATAATACAATTGGTTGCTTTCATTACAACAATAAGCATTTTTTATAAATTTAG
AATTAGATTTGAGGAAACCT

Downstream 100 bases:

>100_bases
CTTTTATCTCATTCATAAAAAAGGGCTTGTTATTACAAGCCCTTTTTTATGTCAGTGTTATTTTTGCTTTAGCGTAGCAA
CTTCCTCTTGAGTTTCTTGA

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MLDQLRAMGVFACVVEKSSFSGAARELGITTSAVSQQIRSLENEMDVILLHRSTRKLSLTEAGQAFFSSCQEMLAAAERG
KIRINELRDDLIGDLRIATTPDLAVQHIIPALSHWMSAHRGLSVHFEVGHRYIDLIEERIDIAVRMSSTAVEESDSVIPM
AFVDQILVASPSYLNQTSPILHPNDLNNHELLSINAMNDSRSFNFQHAKTGEKLNIEMASRLQSNNLQVAKALCQQGHGI
ARILYLDAQKELKNGSLIEILPDWKLPAFTLYAEIAKHDQQPMKIQRCVEALKQYFSQLAGGRAMQIVR

Sequences:

>Translated_309_residues
MLDQLRAMGVFACVVEKSSFSGAARELGITTSAVSQQIRSLENEMDVILLHRSTRKLSLTEAGQAFFSSCQEMLAAAERG
KIRINELRDDLIGDLRIATTPDLAVQHIIPALSHWMSAHRGLSVHFEVGHRYIDLIEERIDIAVRMSSTAVEESDSVIPM
AFVDQILVASPSYLNQTSPILHPNDLNNHELLSINAMNDSRSFNFQHAKTGEKLNIEMASRLQSNNLQVAKALCQQGHGI
ARILYLDAQKELKNGSLIEILPDWKLPAFTLYAEIAKHDQQPMKIQRCVEALKQYFSQLAGGRAMQIVR
>Mature_309_residues
MLDQLRAMGVFACVVEKSSFSGAARELGITTSAVSQQIRSLENEMDVILLHRSTRKLSLTEAGQAFFSSCQEMLAAAERG
KIRINELRDDLIGDLRIATTPDLAVQHIIPALSHWMSAHRGLSVHFEVGHRYIDLIEERIDIAVRMSSTAVEESDSVIPM
AFVDQILVASPSYLNQTSPILHPNDLNNHELLSINAMNDSRSFNFQHAKTGEKLNIEMASRLQSNNLQVAKALCQQGHGI
ARILYLDAQKELKNGSLIEILPDWKLPAFTLYAEIAKHDQQPMKIQRCVEALKQYFSQLAGGRAMQIVR

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=305, Percent_Identity=29.8360655737705, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=28.956228956229, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87081978, Length=305, Percent_Identity=28.5245901639344, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789440, Length=298, Percent_Identity=28.5234899328859, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1787589, Length=277, Percent_Identity=25.9927797833935, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI145693193, Length=272, Percent_Identity=26.1029411764706, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787128, Length=267, Percent_Identity=26.2172284644195, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1789173, Length=264, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI157672245, Length=155, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786508, Length=88, Percent_Identity=39.7727272727273, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786448, Length=257, Percent_Identity=24.5136186770428, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788706, Length=269, Percent_Identity=25.6505576208178, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790011, Length=315, Percent_Identity=23.1746031746032, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34517; Mature: 34517

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDQLRAMGVFACVVEKSSFSGAARELGITTSAVSQQIRSLENEMDVILLHRSTRKLSLT
CCCHHHHHHHHHEEEECCCCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEHH
EAGQAFFSSCQEMLAAAERGKIRINELRDDLIGDLRIATTPDLAVQHIIPALSHWMSAHR
HHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHC
GLSVHFEVGHRYIDLIEERIDIAVRMSSTAVEESDSVIPMAFVDQILVASPSYLNQTSPI
CCEEEEHHHHHHHHHHHHHHHEEEEECHHHHCCCCCCCHHHHHHHHHHCCCHHCCCCCCC
LHPNDLNNHELLSINAMNDSRSFNFQHAKTGEKLNIEMASRLQSNNLQVAKALCQQGHGI
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHCCCCHHHHHHHHHCCCCE
ARILYLDAQKELKNGSLIEILPDWKLPAFTLYAEIAKHDQQPMKIQRCVEALKQYFSQLA
EEEEEEECHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
GGRAMQIVR
CCCEEEECC
>Mature Secondary Structure
MLDQLRAMGVFACVVEKSSFSGAARELGITTSAVSQQIRSLENEMDVILLHRSTRKLSLT
CCCHHHHHHHHHEEEECCCCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEHH
EAGQAFFSSCQEMLAAAERGKIRINELRDDLIGDLRIATTPDLAVQHIIPALSHWMSAHR
HHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHC
GLSVHFEVGHRYIDLIEERIDIAVRMSSTAVEESDSVIPMAFVDQILVASPSYLNQTSPI
CCEEEEHHHHHHHHHHHHHHHEEEEECHHHHCCCCCCCHHHHHHHHHHCCCHHCCCCCCC
LHPNDLNNHELLSINAMNDSRSFNFQHAKTGEKLNIEMASRLQSNNLQVAKALCQQGHGI
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHCCCCHHHHHHHHHCCCCE
ARILYLDAQKELKNGSLIEILPDWKLPAFTLYAEIAKHDQQPMKIQRCVEALKQYFSQLA
EEEEEEECHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
GGRAMQIVR
CCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]