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The map label for this gene is entD [C]

Identifier: 213158091

GI number: 213158091

Start: 2881925

End: 2882680

Strand: Reverse

Name: entD [C]

Synonym: AB57_2803

Alternate gene names: 213158091

Gene position: 2882680-2881925 (Counterclockwise)

Preceding gene: 213158092

Following gene: 213158090

Centisome position: 71.17

GC content: 31.75

Gene sequence:

>756_bases
ATGAATACGAAGAAGCAGTTAAGTAGAGGGGCTAATTCATGTCTGGATGAAATAAATATTCAATATGAAAAGCTAACAGC
TTTCGGGCTAGATATACATAAAGTCCAGCTCAGCCAAATCAAAGAAATACCTCAGCTTGATCATATCTATCAGGAGCTGA
ATATATTTCTTCCACCGAATATAAAAAGCTCACGCTTCATTCGTCAATTAGAGTTCTTGACGGGGCGCTTAGCAGCAAAA
TATGCATTACAAAGCTTTAACTTACAAGATTCTATTGTCTATCAAGGTAGACATGGGGAACCCCTATGGCCCGAAGGAGT
GATGGGGGGTATTAGTCATGTTGGATCAAAAAAATCATGTTATGCCATCGCATATGCTAGAAATAACACACCTAAAGAAA
AAATATTTGGAATCGATATAGAGTCTCAAAAACATCATATTTTTTTTCAAAAGAAAGATGAATTTTATGATGTTTTTCTC
AATAAAAACGAGCAAGAAGAAATTGAAAAGCTACTAAAAGATCAAGCATATTTATATTTGATAATATTCTCCGCTAAAGA
AAGTATCATTAAGGCATTTTATTTAAAATATAAGCAAATTATTGATTTTAAAAATATAAAACTTAAAGCACTAGATGGCG
CGTTTCTTTATTTTTACCTTAGACAAGAAAGTTTAAGCGGGATAACTCTAGAGGTTAAAGTTTATTTTTTTCATACAAAT
AACGAGATAATTACAATTTCTTGCATTGAAAACTAA

Upstream 100 bases:

>100_bases
CATTTCTACTTTCTCAATCCCGAGACTCGAGTAAAGATGCTTGAAAATATTGCTGCCATCGTTGAAACATTGACTGTGAA
TATTGAATAAAGTCCATGCT

Downstream 100 bases:

>100_bases
ATTTGTTATTGATAATAATAATCATTTGCATTAATGTGTGTTTTAGTATTTTTATATCCTTATATTTAAAAAGAAGTACT
ACAGAATTTGCTTGAAAAAA

Product: probable acinetobactin biosynthesis protein

Products: pyrophosphate; AMP; enterobactin; aryl carrier protein/isochorismatase; 3',5'-ADP; serine activating enzyme + [C]

Alternate protein names: 4-Phosphopantetheinyl Transferase Family Protein; Phosphopantetheinyl Transferase; EntD-Related Protein; 4-Phosphopantetheinyl Tranferase

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MNTKKQLSRGANSCLDEINIQYEKLTAFGLDIHKVQLSQIKEIPQLDHIYQELNIFLPPNIKSSRFIRQLEFLTGRLAAK
YALQSFNLQDSIVYQGRHGEPLWPEGVMGGISHVGSKKSCYAIAYARNNTPKEKIFGIDIESQKHHIFFQKKDEFYDVFL
NKNEQEEIEKLLKDQAYLYLIIFSAKESIIKAFYLKYKQIIDFKNIKLKALDGAFLYFYLRQESLSGITLEVKVYFFHTN
NEIITISCIEN

Sequences:

>Translated_251_residues
MNTKKQLSRGANSCLDEINIQYEKLTAFGLDIHKVQLSQIKEIPQLDHIYQELNIFLPPNIKSSRFIRQLEFLTGRLAAK
YALQSFNLQDSIVYQGRHGEPLWPEGVMGGISHVGSKKSCYAIAYARNNTPKEKIFGIDIESQKHHIFFQKKDEFYDVFL
NKNEQEEIEKLLKDQAYLYLIIFSAKESIIKAFYLKYKQIIDFKNIKLKALDGAFLYFYLRQESLSGITLEVKVYFFHTN
NEIITISCIEN
>Mature_251_residues
MNTKKQLSRGANSCLDEINIQYEKLTAFGLDIHKVQLSQIKEIPQLDHIYQELNIFLPPNIKSSRFIRQLEFLTGRLAAK
YALQSFNLQDSIVYQGRHGEPLWPEGVMGGISHVGSKKSCYAIAYARNNTPKEKIFGIDIESQKHHIFFQKKDEFYDVFL
NKNEQEEIEKLLKDQAYLYLIIFSAKESIIKAFYLKYKQIIDFKNIKLKALDGAFLYFYLRQESLSGITLEVKVYFFHTN
NEIITISCIEN

Specific function: Catalyzes The Transfer Of The 4'-Phosphopantetheine Moiety From Coenzyme A To Apo-Domains Of Both Entb (An Arcp Domain) And Entf (A Pcp Domain). Plays An Essential Role In The Assembly Of The Enterobactin. [C]

COG id: COG2977

COG function: function code Q; Phosphopantetheinyl transferase component of siderophore synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.8.- [C]

Molecular weight: Translated: 29282; Mature: 29282

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKKQLSRGANSCLDEINIQYEKLTAFGLDIHKVQLSQIKEIPQLDHIYQELNIFLPPN
CCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEHHHHHHCCCHHHHHHHHCEEEECCC
IKSSRFIRQLEFLTGRLAAKYALQSFNLQDSIVYQGRHGEPLWPEGVMGGISHVGSKKSC
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCE
YAIAYARNNTPKEKIFGIDIESQKHHIFFQKKDEFYDVFLNKNEQEEIEKLLKDQAYLYL
EEEEEECCCCCHHHEEEEEECCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHCCCEEEE
IIFSAKESIIKAFYLKYKQIIDFKNIKLKALDGAFLYFYLRQESLSGITLEVKVYFFHTN
EEEECHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCCCEEEEEEEEEEECC
NEIITISCIEN
CCEEEEEEECC
>Mature Secondary Structure
MNTKKQLSRGANSCLDEINIQYEKLTAFGLDIHKVQLSQIKEIPQLDHIYQELNIFLPPN
CCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEHHHHHHCCCHHHHHHHHCEEEECCC
IKSSRFIRQLEFLTGRLAAKYALQSFNLQDSIVYQGRHGEPLWPEGVMGGISHVGSKKSC
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCE
YAIAYARNNTPKEKIFGIDIESQKHHIFFQKKDEFYDVFLNKNEQEEIEKLLKDQAYLYL
EEEEEECCCCCHHHEEEEEECCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHCCCEEEE
IIFSAKESIIKAFYLKYKQIIDFKNIKLKALDGAFLYFYLRQESLSGITLEVKVYFFHTN
EEEECHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCCCEEEEEEEEEEECC
NEIITISCIEN
CCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate; Coenzyme A; apo-EntB; apo-serine activating enzyme [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin Coenzyme A + apo-EntB = aryl carrier protein/isochorismatase + 3',5'-ADP Coenzyme A + apo-serine activating enzyme = 3',5'-ADP + serine activating enzyme [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA