| Definition | Acinetobacter baumannii AB0057, complete genome. |
|---|---|
| Accession | NC_011586 |
| Length | 4,050,513 |
Click here to switch to the map view.
The map label for this gene is fadH [H]
Identifier: 213157966
GI number: 213157966
Start: 3570568
End: 3571479
Strand: Reverse
Name: fadH [H]
Synonym: AB57_3460
Alternate gene names: 213157966
Gene position: 3571479-3570568 (Counterclockwise)
Preceding gene: 213157967
Following gene: 213157965
Centisome position: 88.17
GC content: 42.76
Gene sequence:
>912_bases ATGAGTTATCAATCAATATTTAGACCAGATGCTTTCGCCAATAAAGTCATTATTGTGACAGGTGGTGGCTCAGGAATTGG ACGCTGTACGGCACATGAACTTGCCGCTTTGGGTGCACAAGTAGTGATTACAGGACGCAAAATTGAAAAATTAGAGAAAG TAAGCCAAGAAATAATAGAAGATGGGGGCTTAGTTCATTTCATTGTTTGTGATAACCGTGAAGAAGAACAAGTGAAAAAT ATGATTGCCGAAGTGATTGAGAAATTCGGCAAACTCGATGGTTTGGTAAATAATGCAGGCGGGCAGTTCCCCTCAGCTTT AGAGAATATTTCGGCGAATGGTTTCGATGCAGTCGTGCGTAATAATTTACACGCAACTTTCTATTTAATGCGTGAAGCTT ATAACCAATGGATGGCTAAACATGGTGGCAGTATTGTCAATATGACTGCTGATATGTGGGGTGGCATGCCAGGAATGGGA CATTCTGGTGCTGCGCGTTCAGGGGTTGATAACTTAACTAAAACAGCATCGGTTGAGTGGGGCAAATCTGGTGTTCGTGT AAATGCGGTTGCACCGGGGTGGATTGTATCATCCGGTATGGATAATTATAGCGGTGATTTTGCCAAAGTAATTATTCCAA GTCTTGCTGGCAATGTACCGTTAAAACGTATGGGAACTGAGTCGGAAGTCTCATCGGCAATTTGTTATTTACTGTCAGAT GCTGCGGCTTTTGTGTCAGGTGTAACTTTGCGTATTGATGGCGCTGCATCGCAAGGGACACGCATGTACCCACTAGCCGA AGCAACAAATAGTCAGTCTTATAATGGTTTCCATCGCGCGTTTATTCCTGAAATTTTTAAAAAAGATAAGACTGCGAAAG TCGAGCAAAGCAATAATTCAGGCTCGGAGTGA
Upstream 100 bases:
>100_bases TTGATCCGCAAGGTAAAGCCTTTGCCCAACAGTTATTGGATATGCCTGTTAAAGTTCCGGCACATCTTTTAGAAAAATAA AATGAATGGATGAAACAAAG
Downstream 100 bases:
>100_bases GGAATAAAAAATGACCATTCTTCAATCCGAAATTACTGTTGGTAGTGAACAGTATCAAAAGAATAAAGAGGCACTACTTG CTCAACTGAATGAAGTCCGT
Product: oxidoreductase short-chain dehydrogenase/reductase family
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 303; Mature: 302
Protein sequence:
>303_residues MSYQSIFRPDAFANKVIIVTGGGSGIGRCTAHELAALGAQVVITGRKIEKLEKVSQEIIEDGGLVHFIVCDNREEEQVKN MIAEVIEKFGKLDGLVNNAGGQFPSALENISANGFDAVVRNNLHATFYLMREAYNQWMAKHGGSIVNMTADMWGGMPGMG HSGAARSGVDNLTKTASVEWGKSGVRVNAVAPGWIVSSGMDNYSGDFAKVIIPSLAGNVPLKRMGTESEVSSAICYLLSD AAAFVSGVTLRIDGAASQGTRMYPLAEATNSQSYNGFHRAFIPEIFKKDKTAKVEQSNNSGSE
Sequences:
>Translated_303_residues MSYQSIFRPDAFANKVIIVTGGGSGIGRCTAHELAALGAQVVITGRKIEKLEKVSQEIIEDGGLVHFIVCDNREEEQVKN MIAEVIEKFGKLDGLVNNAGGQFPSALENISANGFDAVVRNNLHATFYLMREAYNQWMAKHGGSIVNMTADMWGGMPGMG HSGAARSGVDNLTKTASVEWGKSGVRVNAVAPGWIVSSGMDNYSGDFAKVIIPSLAGNVPLKRMGTESEVSSAICYLLSD AAAFVSGVTLRIDGAASQGTRMYPLAEATNSQSYNGFHRAFIPEIFKKDKTAKVEQSNNSGSE >Mature_302_residues SYQSIFRPDAFANKVIIVTGGGSGIGRCTAHELAALGAQVVITGRKIEKLEKVSQEIIEDGGLVHFIVCDNREEEQVKNM IAEVIEKFGKLDGLVNNAGGQFPSALENISANGFDAVVRNNLHATFYLMREAYNQWMAKHGGSIVNMTADMWGGMPGMGH SGAARSGVDNLTKTASVEWGKSGVRVNAVAPGWIVSSGMDNYSGDFAKVIIPSLAGNVPLKRMGTESEVSSAICYLLSDA AAFVSGVTLRIDGAASQGTRMYPLAEATNSQSYNGFHRAFIPEIFKKDKTAKVEQSNNSGSE
Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=273, Percent_Identity=42.1245421245421, Blast_Score=217, Evalue=1e-56, Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=32.5581395348837, Blast_Score=137, Evalue=1e-32, Organism=Homo sapiens, GI4503301, Length=259, Percent_Identity=32.4324324324324, Blast_Score=124, Evalue=9e-29, Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=31.3304721030043, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=27.6264591439689, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI5031737, Length=265, Percent_Identity=27.1698113207547, Blast_Score=89, Evalue=7e-18, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=27.9352226720648, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI33667109, Length=212, Percent_Identity=28.3018867924528, Blast_Score=82, Evalue=8e-16, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=28.6290322580645, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI4504505, Length=195, Percent_Identity=29.7435897435897, Blast_Score=75, Evalue=9e-14, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=25.6916996047431, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI4503817, Length=191, Percent_Identity=27.7486910994764, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI31542939, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI209862901, Length=86, Percent_Identity=44.1860465116279, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI19923983, Length=86, Percent_Identity=44.1860465116279, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=26.9430051813472, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=34.5528455284553, Blast_Score=108, Evalue=6e-25, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=29.5081967213115, Blast_Score=102, Evalue=4e-23, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=26.8774703557312, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=28.8, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=28.6885245901639, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=27.3469387755102, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI87082160, Length=267, Percent_Identity=29.9625468164794, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1789378, Length=240, Percent_Identity=27.0833333333333, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=30, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=26.1538461538462, Blast_Score=79, Evalue=5e-16, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=25.1012145748988, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787526, Length=203, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=25.9541984732824, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI1787820, Length=201, Percent_Identity=25.3731343283582, Blast_Score=64, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=35.6862745098039, Blast_Score=133, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=33.7209302325581, Blast_Score=129, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=31.4176245210728, Blast_Score=119, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=29.8850574712644, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=29.8850574712644, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=29.4339622641509, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=31.2, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17561272, Length=256, Percent_Identity=33.59375, Blast_Score=107, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=31.8181818181818, Blast_Score=106, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=29.1187739463602, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=31.203007518797, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=30.5343511450382, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.1853281853282, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=29.0076335877863, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=30.4, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=28.996282527881, Blast_Score=100, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560220, Length=194, Percent_Identity=34.5360824742268, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=29.3877551020408, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=29.9595141700405, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=29.3233082706767, Blast_Score=92, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=28.1853281853282, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=29.6, Blast_Score=91, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=29.4117647058824, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI72000259, Length=277, Percent_Identity=27.4368231046931, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=31.4741035856574, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=25.0996015936255, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=26.615969581749, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=27.0588235294118, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=26.8482490272374, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17555612, Length=223, Percent_Identity=30.9417040358744, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17564282, Length=209, Percent_Identity=27.7511961722488, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17508895, Length=215, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=271, Percent_Identity=34.3173431734317, Blast_Score=146, Evalue=4e-36, Organism=Saccharomyces cerevisiae, GI6322861, Length=242, Percent_Identity=26.4462809917355, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=9e-13, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=35.4581673306773, Blast_Score=129, Evalue=3e-30, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=33.4661354581673, Blast_Score=127, Evalue=8e-30, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=34.8, Blast_Score=126, Evalue=1e-29, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=31.6205533596838, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=34.136546184739, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=31.3253012048193, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=32.4, Blast_Score=96, Evalue=4e-20, Organism=Drosophila melanogaster, GI17737361, Length=265, Percent_Identity=27.9245283018868, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI28571387, Length=259, Percent_Identity=25.4826254826255, Blast_Score=72, Evalue=6e-13, Organism=Drosophila melanogaster, GI24663911, Length=212, Percent_Identity=27.3584905660377, Blast_Score=65, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.34 [H]
Molecular weight: Translated: 32348; Mature: 32217
Theoretical pI: Translated: 6.52; Mature: 6.52
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSYQSIFRPDAFANKVIIVTGGGSGIGRCTAHELAALGAQVVITGRKIEKLEKVSQEIIE CCCHHHCCCCHHHCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHH DGGLVHFIVCDNREEEQVKNMIAEVIEKFGKLDGLVNNAGGQFPSALENISANGFDAVVR CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHH NNLHATFYLMREAYNQWMAKHGGSIVNMTADMWGGMPGMGHSGAARSGVDNLTKTASVEW CCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCC GKSGVRVNAVAPGWIVSSGMDNYSGDFAKVIIPSLAGNVPLKRMGTESEVSSAICYLLSD CCCCEEEEEECCCHHEECCCCCCCCCHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHH AAAFVSGVTLRIDGAASQGTRMYPLAEATNSQSYNGFHRAFIPEIFKKDKTAKVEQSNNS HHHHHCCCEEEEECCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCC GSE CCC >Mature Secondary Structure SYQSIFRPDAFANKVIIVTGGGSGIGRCTAHELAALGAQVVITGRKIEKLEKVSQEIIE CCHHHCCCCHHHCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHH DGGLVHFIVCDNREEEQVKNMIAEVIEKFGKLDGLVNNAGGQFPSALENISANGFDAVVR CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHH NNLHATFYLMREAYNQWMAKHGGSIVNMTADMWGGMPGMGHSGAARSGVDNLTKTASVEW CCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCC GKSGVRVNAVAPGWIVSSGMDNYSGDFAKVIIPSLAGNVPLKRMGTESEVSSAICYLLSD CCCCEEEEEECCCHHEECCCCCCCCCHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHH AAAFVSGVTLRIDGAASQGTRMYPLAEATNSQSYNGFHRAFIPEIFKKDKTAKVEQSNNS HHHHHCCCEEEEECCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCC GSE CCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]