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The map label for this gene is baeS [H]

Identifier: 213157896

GI number: 213157896

Start: 3493167

End: 3494723

Strand: Reverse

Name: baeS [H]

Synonym: AB57_3388

Alternate gene names: 213157896

Gene position: 3494723-3493167 (Counterclockwise)

Preceding gene: 213157901

Following gene: 213157895

Centisome position: 86.28

GC content: 38.66

Gene sequence:

>1557_bases
ATGCAAAAGAACTTTGCCAAATATGTAGCCGATGTTGAAATGCAAAAGCTAGATCGGCTCATTACTAATCTGGGAAATGT
ATATACCGTTTATCATGATTGGGGGAATGCGATTCAGGCGCAAATCTTACAAATTGAAGGAACGGCAGCACCAGATGATT
ATGACCGTCTTTCCCAGTGGTGGTTACGGCGCCAATATGATATTGCCATTCAGCAGCATTCTTTCGATGAACACACTCTC
ATTAATATTTCTCCAGATGCGGGAACGGTAAATAAAAACTCTATTTTTAGTGATGAAGAACTACGTACACTTGAGCAAAA
CTTACCTTCGGAATATCAACCGTTTGAAGGTTTAAGATTCCCGCTAAGTGCAAACCAGTTTCGTCCAAGCGATGATAAAA
ACAAATCAAAAAAAGGAAGCCTCAAAGACATTGAGACGCAAAATGGTAAGAAGCGTTTTATTGCTTTACCAGACCGGCTG
GGCTTAAGTTCTCGTTTATCTTTATATGATGCCAAACACCAGTTCGTAGTGGGTGAACCGCCGTCTTCGGATCAGATGTC
TTATCGCCCGATTATGGTCAATAGTCAGGTCGTAGGTTATTTAGGTCTAAAACCAGTTTTAGATAAAGAAGATGCATTAA
GTATTAATTTCTTCAGTAATCAAAAGCGCTATTTACTTTTAATTTATGCCTTAACATTACTGTCGAGTTTAGTTGCAGCA
CTTTTAATGGCAACTTATTTTAAAAAGCCAATTCAGCGTCTATTAAATGCAACAAATGAGTTAACAAAAGGTAATTATCA
ACACCAAGTTGTGATTAAACGAAATGATGAGTTAGGTGATTTATCTACTCAATTAAATCATTTAGCTGAAATTTTACATC
AGCATGAAGAATCACGACGTCAATGGGTTGCAGATACCTCTCATGAATTGAAAACTCCATTGGCTGTTTTGCAAGCGCAG
ATTGAAGCGATGCAAGATGGTATCCGAAAGGCAACACCTGAACATCTTGATGCCATGATGCGACAAGTTTCGAGTTTAAA
GAAATTGACACAAGATCTGGCAGACTTGGCTCAGGCTGATGCTCAACAACTTAAATGTTATTTGAGTTCGGTTAATCCTT
GGGAAGTTATACTGCAAGAAGTCGAAAATTTCAGACCTAAACTCGAACAAGCAGGGTTAGAAATTGAGGTGGAAGGTGAA
GGCGCTTCTTTATTGTTAGACCGTGATCGATTTAAACAAATTATTGTTAACTTGATCGGTAATAGTATTCGCTATACCGA
AACAGGTGGAAAGATTCATATTCATACAAATCAAACGTCTCAGGAGTGGACTTTATATGTTGATGACAGTCCATTTGGTT
TAAGTGATGAGCAATTATCACGTTTAGGTGAACGTTTTTATCGTGTCGATGATTCGCGTACGCGTAGTACAGGTGGAACA
GGACTAGGCTTAGCTTTATCTTGTAAAATTGCGCAGGCGCTTGGTGGTACACTCAGTTTTGAACACTCACCATTAGGTGG
TTTACGTTGTGTACTGACCTTTAAAAAGCAGAGTTAA

Upstream 100 bases:

>100_bases
GAACGTTCTACGTGTTCCCATAGCCTTGCGGTTATTTTTAACGGTCTTGCTTACCACGCTGTTAATTGCAACTGCAAGTT
TGAGTGTTCTGCACTGGACG

Downstream 100 bases:

>100_bases
ATAAAAGGAAAAATGGCCCATGAAACATATTATGTTGGTTGAGGATGAAGTCGAGTTAGCGCATCTGGTGCGTGATTATC
TTGAGGCTGCTGGATTCGAA

Product: two component signal transduction system kinase sensor component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MQKNFAKYVADVEMQKLDRLITNLGNVYTVYHDWGNAIQAQILQIEGTAAPDDYDRLSQWWLRRQYDIAIQQHSFDEHTL
INISPDAGTVNKNSIFSDEELRTLEQNLPSEYQPFEGLRFPLSANQFRPSDDKNKSKKGSLKDIETQNGKKRFIALPDRL
GLSSRLSLYDAKHQFVVGEPPSSDQMSYRPIMVNSQVVGYLGLKPVLDKEDALSINFFSNQKRYLLLIYALTLLSSLVAA
LLMATYFKKPIQRLLNATNELTKGNYQHQVVIKRNDELGDLSTQLNHLAEILHQHEESRRQWVADTSHELKTPLAVLQAQ
IEAMQDGIRKATPEHLDAMMRQVSSLKKLTQDLADLAQADAQQLKCYLSSVNPWEVILQEVENFRPKLEQAGLEIEVEGE
GASLLLDRDRFKQIIVNLIGNSIRYTETGGKIHIHTNQTSQEWTLYVDDSPFGLSDEQLSRLGERFYRVDDSRTRSTGGT
GLGLALSCKIAQALGGTLSFEHSPLGGLRCVLTFKKQS

Sequences:

>Translated_518_residues
MQKNFAKYVADVEMQKLDRLITNLGNVYTVYHDWGNAIQAQILQIEGTAAPDDYDRLSQWWLRRQYDIAIQQHSFDEHTL
INISPDAGTVNKNSIFSDEELRTLEQNLPSEYQPFEGLRFPLSANQFRPSDDKNKSKKGSLKDIETQNGKKRFIALPDRL
GLSSRLSLYDAKHQFVVGEPPSSDQMSYRPIMVNSQVVGYLGLKPVLDKEDALSINFFSNQKRYLLLIYALTLLSSLVAA
LLMATYFKKPIQRLLNATNELTKGNYQHQVVIKRNDELGDLSTQLNHLAEILHQHEESRRQWVADTSHELKTPLAVLQAQ
IEAMQDGIRKATPEHLDAMMRQVSSLKKLTQDLADLAQADAQQLKCYLSSVNPWEVILQEVENFRPKLEQAGLEIEVEGE
GASLLLDRDRFKQIIVNLIGNSIRYTETGGKIHIHTNQTSQEWTLYVDDSPFGLSDEQLSRLGERFYRVDDSRTRSTGGT
GLGLALSCKIAQALGGTLSFEHSPLGGLRCVLTFKKQS
>Mature_518_residues
MQKNFAKYVADVEMQKLDRLITNLGNVYTVYHDWGNAIQAQILQIEGTAAPDDYDRLSQWWLRRQYDIAIQQHSFDEHTL
INISPDAGTVNKNSIFSDEELRTLEQNLPSEYQPFEGLRFPLSANQFRPSDDKNKSKKGSLKDIETQNGKKRFIALPDRL
GLSSRLSLYDAKHQFVVGEPPSSDQMSYRPIMVNSQVVGYLGLKPVLDKEDALSINFFSNQKRYLLLIYALTLLSSLVAA
LLMATYFKKPIQRLLNATNELTKGNYQHQVVIKRNDELGDLSTQLNHLAEILHQHEESRRQWVADTSHELKTPLAVLQAQ
IEAMQDGIRKATPEHLDAMMRQVSSLKKLTQDLADLAQADAQQLKCYLSSVNPWEVILQEVENFRPKLEQAGLEIEVEGE
GASLLLDRDRFKQIIVNLIGNSIRYTETGGKIHIHTNQTSQEWTLYVDDSPFGLSDEQLSRLGERFYRVDDSRTRSTGGT
GLGLALSCKIAQALGGTLSFEHSPLGGLRCVLTFKKQS

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=350, Percent_Identity=36.5714285714286, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1786783, Length=330, Percent_Identity=26.969696969697, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1787894, Length=332, Percent_Identity=27.4096385542169, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786600, Length=200, Percent_Identity=32.5, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1790346, Length=286, Percent_Identity=29.7202797202797, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=30, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1789149, Length=217, Percent_Identity=29.4930875576037, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1790861, Length=351, Percent_Identity=24.7863247863248, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788279, Length=284, Percent_Identity=26.7605633802817, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081816, Length=257, Percent_Identity=27.2373540856031, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787374, Length=326, Percent_Identity=24.5398773006135, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=24.4635193133047, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=23.4567901234568, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789403, Length=247, Percent_Identity=25.9109311740891, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790551, Length=247, Percent_Identity=26.7206477732794, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1788549, Length=210, Percent_Identity=22.8571428571429, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58696; Mature: 58696

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKNFAKYVADVEMQKLDRLITNLGNVYTVYHDWGNAIQAQILQIEGTAAPDDYDRLSQW
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHH
WLRRQYDIAIQQHSFDEHTLINISPDAGTVNKNSIFSDEELRTLEQNLPSEYQPFEGLRF
HHHHHHHEEEEECCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
PLSANQFRPSDDKNKSKKGSLKDIETQNGKKRFIALPDRLGLSSRLSLYDAKHQFVVGEP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHEECCCCEEECCC
PSSDQMSYRPIMVNSQVVGYLGLKPVLDKEDALSINFFSNQKRYLLLIYALTLLSSLVAA
CCCCCCCCCCEEECCCEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
LLMATYFKKPIQRLLNATNELTKGNYQHQVVIKRNDELGDLSTQLNHLAEILHQHEESRR
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
QWVADTSHELKTPLAVLQAQIEAMQDGIRKATPEHLDAMMRQVSSLKKLTQDLADLAQAD
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQLKCYLSSVNPWEVILQEVENFRPKLEQAGLEIEVEGEGASLLLDRDRFKQIIVNLIG
HHHHHHHHHCCCHHHHHHHHHHHHCHHHHHCCCEEEECCCCCEEEECHHHHHHHHHHHHC
NSIRYTETGGKIHIHTNQTSQEWTLYVDDSPFGLSDEQLSRLGERFYRVDDSRTRSTGGT
CCEEEEECCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GLGLALSCKIAQALGGTLSFEHSPLGGLRCVLTFKKQS
CCCCEEHHHHHHHCCCCEEECCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MQKNFAKYVADVEMQKLDRLITNLGNVYTVYHDWGNAIQAQILQIEGTAAPDDYDRLSQW
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHH
WLRRQYDIAIQQHSFDEHTLINISPDAGTVNKNSIFSDEELRTLEQNLPSEYQPFEGLRF
HHHHHHHEEEEECCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
PLSANQFRPSDDKNKSKKGSLKDIETQNGKKRFIALPDRLGLSSRLSLYDAKHQFVVGEP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHEECCCCEEECCC
PSSDQMSYRPIMVNSQVVGYLGLKPVLDKEDALSINFFSNQKRYLLLIYALTLLSSLVAA
CCCCCCCCCCEEECCCEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
LLMATYFKKPIQRLLNATNELTKGNYQHQVVIKRNDELGDLSTQLNHLAEILHQHEESRR
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
QWVADTSHELKTPLAVLQAQIEAMQDGIRKATPEHLDAMMRQVSSLKKLTQDLADLAQAD
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQLKCYLSSVNPWEVILQEVENFRPKLEQAGLEIEVEGEGASLLLDRDRFKQIIVNLIG
HHHHHHHHHCCCHHHHHHHHHHHHCHHHHHCCCEEEECCCCCEEEECHHHHHHHHHHHHC
NSIRYTETGGKIHIHTNQTSQEWTLYVDDSPFGLSDEQLSRLGERFYRVDDSRTRSTGGT
CCEEEEECCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GLGLALSCKIAQALGGTLSFEHSPLGGLRCVLTFKKQS
CCCCEEHHHHHHHCCCCEEECCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]