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The map label for this gene is ahpC [C]

Identifier: 213157877

GI number: 213157877

Start: 3473132

End: 3473773

Strand: Direct

Name: ahpC [C]

Synonym: AB57_3367

Alternate gene names: 213157877

Gene position: 3473132-3473773 (Clockwise)

Preceding gene: 213157874

Following gene: 213157878

Centisome position: 85.75

GC content: 38.32

Gene sequence:

>642_bases
ATGACATTACGATTAGGCGACACAGCCCCTGATTTTCAACAAGAATCAAGCGAAGGCACTATTAATTTTTATGATTTTCT
AGGTGATAGTTGGGGCATTTTATTTTCACACCCGGCCGACTATACGCCAGTATGTACAACTGAATTGGGTTATACAGCAA
AACTAAAAGATGAATTTGAAAAACGTAATGTTAAAGCAATTGCCTTATCTGTAGATGATGTAGAGTCGCACAAAGGCTGG
ATTAATGACATTAACGAAACTCAAAATACAACAGTCAATTTTCCAATTATTGCTGACAAAGACCGCAAAGTATCTGAGCT
ATACGGTTTTATTCATCCGAATGCCAGTGAAACCCTTACTGTTCGTTCTTTAGTGATTATTGACCCACATAAAAAAGTTC
GTCTAATCATCACCTACCCTGCTTCGACTGGTCGTAATTTTAATGAAGTCTTACGTGTTGTTGACTCATTACAATTAACC
GATAAGCATAAAGTGGCTACACCAGCAAACTGGCAACAAGGTGAAGATGTGGTCATTGTCCCTTCTTTAAAAGATGAAGA
GGAAATTAAACAACGCTTCCCTAAAGGTTATACTGCGGTGAAACCTTATTTACGCCTCACACCACAGCCTGAGCAAGATT
AA

Upstream 100 bases:

>100_bases
AAGTTCATAATAAAATATAAAAACAATAATTTTAATAATAAATAAATTGCGGCATAGTCATTTCAACATATAACAAATTT
TAAGCAATTGAGGTTTTACC

Downstream 100 bases:

>100_bases
AGCCTTTAACAAGGCTTTAATCGAAGCGCAAGACAAACGCAGTGCGTAGGCAAGCGTCTGAAAGGTCGCCTGCAAGACAA
ACGCAGCGCGTAGGCAAATA

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTLRLGDTAPDFQQESSEGTINFYDFLGDSWGILFSHPADYTPVCTTELGYTAKLKDEFEKRNVKAIALSVDDVESHKGW
INDINETQNTTVNFPIIADKDRKVSELYGFIHPNASETLTVRSLVIIDPHKKVRLIITYPASTGRNFNEVLRVVDSLQLT
DKHKVATPANWQQGEDVVIVPSLKDEEEIKQRFPKGYTAVKPYLRLTPQPEQD

Sequences:

>Translated_213_residues
MTLRLGDTAPDFQQESSEGTINFYDFLGDSWGILFSHPADYTPVCTTELGYTAKLKDEFEKRNVKAIALSVDDVESHKGW
INDINETQNTTVNFPIIADKDRKVSELYGFIHPNASETLTVRSLVIIDPHKKVRLIITYPASTGRNFNEVLRVVDSLQLT
DKHKVATPANWQQGEDVVIVPSLKDEEEIKQRFPKGYTAVKPYLRLTPQPEQD
>Mature_212_residues
TLRLGDTAPDFQQESSEGTINFYDFLGDSWGILFSHPADYTPVCTTELGYTAKLKDEFEKRNVKAIALSVDDVESHKGWI
NDINETQNTTVNFPIIADKDRKVSELYGFIHPNASETLTVRSLVIIDPHKKVRLIITYPASTGRNFNEVLRVVDSLQLTD
KHKVATPANWQQGEDVVIVPSLKDEEEIKQRFPKGYTAVKPYLRLTPQPEQD

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=221, Percent_Identity=52.0361990950226, Blast_Score=223, Evalue=7e-59,
Organism=Homo sapiens, GI32189392, Length=190, Percent_Identity=33.1578947368421, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=32.6315789473684, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=32.6315789473684, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=32.6315789473684, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI5453549, Length=148, Percent_Identity=33.1081081081081, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI32483377, Length=169, Percent_Identity=31.3609467455621, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI5802974, Length=169, Percent_Identity=31.3609467455621, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=30.5194805194805, Blast_Score=74, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI25153706, Length=199, Percent_Identity=42.713567839196, Blast_Score=169, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI193204376, Length=189, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32565831, Length=189, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17554494, Length=144, Percent_Identity=30.5555555555556, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=56.1320754716981, Blast_Score=235, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6320661, Length=157, Percent_Identity=33.1210191082803, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323613, Length=157, Percent_Identity=31.8471337579618, Blast_Score=79, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=50.2283105022831, Blast_Score=220, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=48.5436893203884, Blast_Score=187, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24652436, Length=206, Percent_Identity=48.5436893203884, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI17975518, Length=206, Percent_Identity=48.5436893203884, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI17157991, Length=168, Percent_Identity=32.7380952380952, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24641739, Length=168, Percent_Identity=32.7380952380952, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21357347, Length=194, Percent_Identity=29.3814432989691, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17738015, Length=199, Percent_Identity=29.1457286432161, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24656348, Length=160, Percent_Identity=31.875, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17864676, Length=160, Percent_Identity=31.875, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24152; Mature: 24021

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRLGDTAPDFQQESSEGTINFYDFLGDSWGILFSHPADYTPVCTTELGYTAKLKDEFE
CEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCEEECCCCCEEHHHHHHH
KRNVKAIALSVDDVESHKGWINDINETQNTTVNFPIIADKDRKVSELYGFIHPNASETLT
HCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHEEECCCCCCEEE
VRSLVIIDPHKKVRLIITYPASTGRNFNEVLRVVDSLQLTDKHKVATPANWQQGEDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
PSLKDEEEIKQRFPKGYTAVKPYLRLTPQPEQD
CCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TLRLGDTAPDFQQESSEGTINFYDFLGDSWGILFSHPADYTPVCTTELGYTAKLKDEFE
EEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCEEECCCCCEEHHHHHHH
KRNVKAIALSVDDVESHKGWINDINETQNTTVNFPIIADKDRKVSELYGFIHPNASETLT
HCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHEEECCCCCCEEE
VRSLVIIDPHKKVRLIITYPASTGRNFNEVLRVVDSLQLTDKHKVATPANWQQGEDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
PSLKDEEEIKQRFPKGYTAVKPYLRLTPQPEQD
CCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]