Click here to switch to the map view.

The map label for this gene is emrE [C]

Identifier: 213157861

GI number: 213157861

Start: 3451617

End: 3451970

Strand: Reverse

Name: emrE [C]

Synonym: AB57_3348

Alternate gene names: 213157861

Gene position: 3451970-3451617 (Counterclockwise)

Preceding gene: 213157862

Following gene: 213157857

Centisome position: 85.22

GC content: 37.57

Gene sequence:

>354_bases
ATGTTCGCTTTAATTTCAAAAATAAATCCTGGTGCTTGGTGGTTAATATTCGCTATTGCGACGGATGTACTTTCAACCTT
TTATTCAGCTAAAGGCAATGGATTAGTTAATAAAACTGCTCAGGGGATTGCTCTAGTTTTGTATATTATCTCTTTTGCAT
GTGCTGCTATTGCTTTGAAATATATGCAAGCTGGAATTTTATATGTGTTGTGGTCTGGGGTGGGGGTATTGGCGACCGCT
TTTCTCGCAAAGATTTTTCTTGGGCAGAACATTGATGTAGCAGGATGGATTGGGATTGGTTTTATTACAGTCGGCTTAAT
GATTATTGCGCAATACTCTAATATCGATGTTTAA

Upstream 100 bases:

>100_bases
TATCAAACTGGTGCTTAAATAGCTTCTAAGTGAAAAGGCTGAACTCAGGTTCAGCTTTTTTTATAAATAATTTTTTAAAT
AAATGAATTGAAGAATAAAA

Downstream 100 bases:

>100_bases
AGCCCTTATAGAAACACTGAGATCTCTATAAGGGCTAAAGATTTAAGTATCTAACTGGCAGTTAACCATCCATTTGACAC
CAAATTGATCAGTAAAAGCA

Product: quaternary ammonium compound-resistance protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: QuateRNAry Ammonium Compound-Resistance Protein; Multidrug Transporter

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MFALISKINPGAWWLIFAIATDVLSTFYSAKGNGLVNKTAQGIALVLYIISFACAAIALKYMQAGILYVLWSGVGVLATA
FLAKIFLGQNIDVAGWIGIGFITVGLMIIAQYSNIDV

Sequences:

>Translated_117_residues
MFALISKINPGAWWLIFAIATDVLSTFYSAKGNGLVNKTAQGIALVLYIISFACAAIALKYMQAGILYVLWSGVGVLATA
FLAKIFLGQNIDVAGWIGIGFITVGLMIIAQYSNIDV
>Mature_117_residues
MFALISKINPGAWWLIFAIATDVLSTFYSAKGNGLVNKTAQGIALVLYIISFACAAIALKYMQAGILYVLWSGVGVLATA
FLAKIFLGQNIDVAGWIGIGFITVGLMIIAQYSNIDV

Specific function: Multidrug Transporter. Confers Resistance To A Wide Range Of Toxic Compounds By Removing Them For The Cells. The Efflux Is Coupled To An Influx Of Protons. Probably Prevents The Incorporation Of Methyl VIologen Into Cells. Involved In Ethidium Bromide Ef

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 12480; Mature: 12480

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFALISKINPGAWWLIFAIATDVLSTFYSAKGNGLVNKTAQGIALVLYIISFACAAIALK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YMQAGILYVLWSGVGVLATAFLAKIFLGQNIDVAGWIGIGFITVGLMIIAQYSNIDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFALISKINPGAWWLIFAIATDVLSTFYSAKGNGLVNKTAQGIALVLYIISFACAAIALK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YMQAGILYVLWSGVGVLATAFLAKIFLGQNIDVAGWIGIGFITVGLMIIAQYSNIDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA