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The map label for this gene is omp38 [H]

Identifier: 213157857

GI number: 213157857

Start: 3447764

End: 3448825

Strand: Reverse

Name: omp38 [H]

Synonym: AB57_3344

Alternate gene names: 213157857

Gene position: 3448825-3447764 (Counterclockwise)

Preceding gene: 213157861

Following gene: 213157850

Centisome position: 85.15

GC content: 42.18

Gene sequence:

>1062_bases
ATGAAATTGAGTCGTATTGCACTTGCTACTATGCTTGTTGCTGCTCCATTAGCTGCTGCTAATGCTGGCGTAACAGTTAC
TCCATTATTGCTTGGTTACACTTTCCAAGACACTCAACACAACAATGGCGGTAAAGATGGCGAGTTAACTAACGGACCTG
AATTACAAGACGATTTATTCGTTGGTGCAGCTCTTGGTATCGAGTTAACACCATGGTTAGGTTTCGAAGCTGAATATAAC
CAAGTTAAAGGTGATGTAGACGGTCTTGCAGCTGGCGCTGAATACAAGCAAAAACAAATCAACGGTAACTTCTATGTTAC
TTCTGATTTAATCACTAAAAACTATGACAGCAAAATCAAGCCATACGTATTGTTAGGTGCTGGTCACTACAAATACGAGA
TTCCTGACCTTTCTTATCACAACGATGAAGAAGGTACTTTAGGTAATGCTGGTGTTGGTGCTTTCTGGCGCTTAAACGAT
GCTCTATCTCTTCGTACAGAAGCTCGTGGTACTTATAACTTTGACGAAAAATTCTGGAACTATACAGCTCTTGCTGGCTT
AAACGTAGTTCTTGGTGGTCACTTGAAGCCTGCTGCTCCTGTAGTAGAAGTTGCTCCAGTTGAACCAACTCCAGTTGCTC
CACAACCACAAGAGTTAACTGAAGACCTTAACATGGAACTTCGTGTGTTCTTTGATACTAACAAATCAAACATCAAAGAC
CAATACAAGCCAGAAATCGCTAAAGTTGCTGAAAAATTATCTGAATACCCTAACGCTACTGCACGTATCGAAGGTCACAC
AGATAACACTGGTCCACGTAAGTTGAACGAACGTTTATCTTTAGCTCGTGCTAACTCTGTTAAATCAGCTCTTGTAAACG
AATACAACGTTGACGCTTCTCGTTTGTCTACTCAAGGTTTCGCTTGGGATCAACCGATTGCTGACAACAAAACTAAAGAA
GGTCGTGCTATGAACCGTCGTGTATTCGCGACAATCACTGGTAGCCGTACTGTAGTAGTTCAACCTGGTCAAGAAGCGGC
AGCTCCTGCAGCAGCTCAATAA

Upstream 100 bases:

>100_bases
AATGTGAATAGCTTAAAAATAATACTGGGGTAAAAATATCTCAGGGGCCAATAAATTTAGGCTGAGCTTGAACAACAATT
GTTATCTCTGGAGGATATCC

Downstream 100 bases:

>100_bases
TTTGAGTTCTTGAACAGTAAAAAAGCGACTCGCTAGAGTCGCTTTTTTTTTATGGCGATTTTTAAAATATTTGGTCATTT
GTAAATCTCCTGATTCATAA

Product: outer membrane protein A

Products: NA

Alternate protein names: Outer membrane protein ompA; Outer membrane protein ompAb [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDTQHNNGGKDGELTNGPELQDDLFVGAALGIELTPWLGFEAEYN
QVKGDVDGLAAGAEYKQKQINGNFYVTSDLITKNYDSKIKPYVLLGAGHYKYEIPDLSYHNDEEGTLGNAGVGAFWRLND
ALSLRTEARGTYNFDEKFWNYTALAGLNVVLGGHLKPAAPVVEVAPVEPTPVAPQPQELTEDLNMELRVFFDTNKSNIKD
QYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKE
GRAMNRRVFATITGSRTVVVQPGQEAAAPAAAQ

Sequences:

>Translated_353_residues
MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDTQHNNGGKDGELTNGPELQDDLFVGAALGIELTPWLGFEAEYN
QVKGDVDGLAAGAEYKQKQINGNFYVTSDLITKNYDSKIKPYVLLGAGHYKYEIPDLSYHNDEEGTLGNAGVGAFWRLND
ALSLRTEARGTYNFDEKFWNYTALAGLNVVLGGHLKPAAPVVEVAPVEPTPVAPQPQELTEDLNMELRVFFDTNKSNIKD
QYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKE
GRAMNRRVFATITGSRTVVVQPGQEAAAPAAAQ
>Mature_353_residues
MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDTQHNNGGKDGELTNGPELQDDLFVGAALGIELTPWLGFEAEYN
QVKGDVDGLAAGAEYKQKQINGNFYVTSDLITKNYDSKIKPYVLLGAGHYKYEIPDLSYHNDEEGTLGNAGVGAFWRLND
ALSLRTEARGTYNFDEKFWNYTALAGLNVVLGGHLKPAAPVVEVAPVEPTPVAPQPQELTEDLNMELRVFFDTNKSNIKD
QYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKE
GRAMNRRVFATITGSRTVVVQPGQEAAAPAAAQ

Specific function: Porin. Induces apoptosis in human laryngeal epithelial HEp-2 cells through caspases-dependent and AIF-dependent pathways. Purified omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochr

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=111, Percent_Identity=45.945945945946, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788957, Length=112, Percent_Identity=40.1785714285714, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR006665
- InterPro:   IPR008722 [H]

Pfam domain/function: PF00691 OmpA; PF05736 OprF [H]

EC number: NA

Molecular weight: Translated: 38357; Mature: 38357

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDTQHNNGGKDGELTNGPELQDDLF
CCCHHHHHHHHHHHHHHHHCCCCCEEEHEEEEEEECCCCCCCCCCCCCCCCCCCCCHHEE
VGAALGIELTPWLGFEAEYNQVKGDVDGLAAGAEYKQKQINGNFYVTSDLITKNYDSKIK
EEEEECEEECCCCCCCCHHHHHCCCHHHHHCCCHHHHHHCCCCEEEEECCCCCCCCCCCC
PYVLLGAGHYKYEIPDLSYHNDEEGTLGNAGVGAFWRLNDALSLRTEARGTYNFDEKFWN
CEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHC
YTALAGLNVVLGGHLKPAAPVVEVAPVEPTPVAPQPQELTEDLNMELRVFFDTNKSNIKD
CHHHHCCEEEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCH
QYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDAS
HHCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSRTVVVQPGQEAAAPAAAQ
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEECCCHHHCCCCCCC
>Mature Secondary Structure
MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDTQHNNGGKDGELTNGPELQDDLF
CCCHHHHHHHHHHHHHHHHCCCCCEEEHEEEEEEECCCCCCCCCCCCCCCCCCCCCHHEE
VGAALGIELTPWLGFEAEYNQVKGDVDGLAAGAEYKQKQINGNFYVTSDLITKNYDSKIK
EEEEECEEECCCCCCCCHHHHHCCCHHHHHCCCHHHHHHCCCCEEEEECCCCCCCCCCCC
PYVLLGAGHYKYEIPDLSYHNDEEGTLGNAGVGAFWRLNDALSLRTEARGTYNFDEKFWN
CEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHC
YTALAGLNVVLGGHLKPAAPVVEVAPVEPTPVAPQPQELTEDLNMELRVFFDTNKSNIKD
CHHHHCCEEEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCH
QYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDAS
HHCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSRTVVVQPGQEAAAPAAAQ
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEECCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA