Click here to switch to the map view.

The map label for this gene is dsbC [H]

Identifier: 213157841

GI number: 213157841

Start: 3430900

End: 3431610

Strand: Direct

Name: dsbC [H]

Synonym: AB57_3325

Alternate gene names: 213157841

Gene position: 3430900-3431610 (Clockwise)

Preceding gene: 213157840

Following gene: 213157842

Centisome position: 84.7

GC content: 36.15

Gene sequence:

>711_bases
ATGAAAACTAAACTTGCTACACTCATGTTGAGTTTGGCTTTTTTCGGTTCTGCTCATGCTGATGTTAAAACACTTGAACA
AAATCTGAAGACAAATTATCCAGACCTCCCTGTAAAAGGTGTCTATCAGTCACCTGTCGCTGGAATTTATGAAGTCTATA
CAAGTGGCCGTATTGTTTATACCAATCAAGATGCAAAATACTTTTTTGTAGGCAATTTAGTTGATATCAAACAACAAAAA
AATATGACAGAAGAGCGAATTGCCGAATTGGGTAAAATTGATGTTAAAAGTCTCCCATTAAATCAGGCAATTAAATACGT
CAAAGGTAAAGGAGAGCGTACTCTTTATATTTTCAGTGACCCTGATTGCCCTTACTGTCAGCGTCTAGAACAAAATATGG
TTGGAGTGGATAACGTAACGGTATATATATTCTTATATCCACTGACCAGCTTACATCCAAATGCTGAAAAGGTTTCTAAT
CAAATCTGGTGCTCTAAAAACCCTTCAGAAGCTTGGACAAATTATATGCTTAACCGTAAATTGCCAGCGGCTAGCAAAAG
CTGTACAAGTCCAATTCAGAAAAATATTGCTTTAGGCCAGAAATTAAATATAGATGGCACACCAACTCTGTTCTTACAAG
ATGGTCAAAGAATCTCTGGTGTACCAAGTGATGCAAAACAGATTGAAGCATTATTACAGTCAGTAAAATAA

Upstream 100 bases:

>100_bases
TCTATAGATACAAAATTCTAATGAATTCATTAAATTAGGGCATCAATTTTTTAAGTTTTCTATGCCATCATAATCCACGT
TGTAATCTAAGAGAAAAAAT

Downstream 100 bases:

>100_bases
TCCAATACGCCACTCTCTTAAGTAGAGTGGCGTATTATTTTTCTCCACAGTTTGCTTTATAGACATCGTTTTATATACAA
ATCGGCTGTTTACTTTCGGC

Product: thiol:disulfide interchange protein DsbC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKTKLATLMLSLAFFGSAHADVKTLEQNLKTNYPDLPVKGVYQSPVAGIYEVYTSGRIVYTNQDAKYFFVGNLVDIKQQK
NMTEERIAELGKIDVKSLPLNQAIKYVKGKGERTLYIFSDPDCPYCQRLEQNMVGVDNVTVYIFLYPLTSLHPNAEKVSN
QIWCSKNPSEAWTNYMLNRKLPAASKSCTSPIQKNIALGQKLNIDGTPTLFLQDGQRISGVPSDAKQIEALLQSVK

Sequences:

>Translated_236_residues
MKTKLATLMLSLAFFGSAHADVKTLEQNLKTNYPDLPVKGVYQSPVAGIYEVYTSGRIVYTNQDAKYFFVGNLVDIKQQK
NMTEERIAELGKIDVKSLPLNQAIKYVKGKGERTLYIFSDPDCPYCQRLEQNMVGVDNVTVYIFLYPLTSLHPNAEKVSN
QIWCSKNPSEAWTNYMLNRKLPAASKSCTSPIQKNIALGQKLNIDGTPTLFLQDGQRISGVPSDAKQIEALLQSVK
>Mature_236_residues
MKTKLATLMLSLAFFGSAHADVKTLEQNLKTNYPDLPVKGVYQSPVAGIYEVYTSGRIVYTNQDAKYFFVGNLVDIKQQK
NMTEERIAELGKIDVKSLPLNQAIKYVKGKGERTLYIFSDPDCPYCQRLEQNMVGVDNVTVYIFLYPLTSLHPNAEKVSN
QIWCSKNPSEAWTNYMLNRKLPAASKSCTSPIQKNIALGQKLNIDGTPTLFLQDGQRISGVPSDAKQIEALLQSVK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=225, Percent_Identity=27.1111111111111, Blast_Score=91, Evalue=5e-20,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26406; Mature: 26406

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKLATLMLSLAFFGSAHADVKTLEQNLKTNYPDLPVKGVYQSPVAGIYEVYTSGRIVY
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCEEEE
TNQDAKYFFVGNLVDIKQQKNMTEERIAELGKIDVKSLPLNQAIKYVKGKGERTLYIFSD
ECCCCCEEEECCEEHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECC
PDCPYCQRLEQNMVGVDNVTVYIFLYPLTSLHPNAEKVSNQIWCSKNPSEAWTNYMLNRK
CCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHCCCEECCCCCHHHHHHHHHCCC
LPAASKSCTSPIQKNIALGQKLNIDGTPTLFLQDGQRISGVPSDAKQIEALLQSVK
CCCCCHHHHHHHHHHHHCCCEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKTKLATLMLSLAFFGSAHADVKTLEQNLKTNYPDLPVKGVYQSPVAGIYEVYTSGRIVY
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCEEEE
TNQDAKYFFVGNLVDIKQQKNMTEERIAELGKIDVKSLPLNQAIKYVKGKGERTLYIFSD
ECCCCCEEEECCEEHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECC
PDCPYCQRLEQNMVGVDNVTVYIFLYPLTSLHPNAEKVSNQIWCSKNPSEAWTNYMLNRK
CCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHCCCEECCCCCHHHHHHHHHCCC
LPAASKSCTSPIQKNIALGQKLNIDGTPTLFLQDGQRISGVPSDAKQIEALLQSVK
CCCCCHHHHHHHHHHHHCCCEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA