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The map label for this gene is mreB [H]

Identifier: 213157800

GI number: 213157800

Start: 3381876

End: 3382892

Strand: Reverse

Name: mreB [H]

Synonym: AB57_3283

Alternate gene names: 213157800

Gene position: 3382892-3381876 (Counterclockwise)

Preceding gene: 213157805

Following gene: 213157799

Centisome position: 83.52

GC content: 42.38

Gene sequence:

>1017_bases
TTGTTTTCGCCGGATCTAGCCATTGATTTAGGTACAGCAAATACACTTATTTATGCACCAGGCCGCGGCATTATATTAAA
TGAACCAACAGTTGTGGCAATTCGTCACAGTGGTTCACAAAAAATTGTTGCTGCTGTAGGTCTAGATGCTAAGCAAATGC
TAGGCCGTACACCTGCGAATATTTCTGCAATTCGTCCAATGAAAGACGGTGTAATTGCAGATTTTGAAGTGACTGAAACC
ATGTTGAATCAGTTTATTGGTAAAGTTCACGAAAAACGTTTGTTCCCACCTGCACCTCGTGTAGTTGTATGTGTACCATG
TAAATCAACTTTGGTCGAGCGCCGTGCAATTCGCGAAGCCGTATTTAATGCGGGTGCTCGTGATGTACGCCTAATTGAAG
AGCCAATGGCTGCTGCAATTGGTGCTGGCATGCCAGTTGAACAAGCATGTGGTTCTATGGTTGTGGATGTTGGTGGTGGT
ACAACTGAAATTGCAATTATTTCATTGCAAGGTTGTGTCTATGCTGATTCTTTACGTATTGGTGGCGATGTATTTGATGA
GCAAATTATCAATTATGTTCGTAAAGCTCACGGTTGCGTAATTGGTGAAACCACAGCTGAAATTATTAAAAAAGAAGTTG
GTATGGCTGTTTCTGATGGTACGACATTAGAAATTGAAGTACGTGGCCGTAACCTTGCAGAAGGTGTACCTCGTGCAATT
ACCGTAACTTCTGACGAAATTACTCAAGCAATTTCTGACCCGTTACAAAGTATTGTAAGCGCGGTGAAATCTGCACTTGA
ACAAACTCCTCCTGAACTTTCTTCTGATATTGCTGAGCGCGGTATTGTGTTGACAGGTGGTGGAGCGTTACTTCGTAACC
TTGATAAATTATTAGCTCAAGAAACCGGTTTACCAGTTGTTGTTGCTGAAGACCCTCTTACTTGTGTAACCCGTGGTGGT
GGTAAAGTATTGGAATTCTTCGACAACCCGAACCATGACATGCTTTTCGTCGGTTAA

Upstream 100 bases:

>100_bases
TGACTTGTTCAAATCATCACATTTAGTTTAAAGTTGCCACCTTGCATCCACATGAAAGTTTAACTGAGAACGAACCGTGA
TTCTAAAACGACTAATTGGC

Downstream 100 bases:

>100_bases
GTTTAAGGATTAGGCGGTGCAACCGAATATTTTTTCAAGACAGCCGCCATCTTTCCGCTCGTTCATTATTGCGGTCATTA
CATGCTTGGTGGTGCTGTTC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MFSPDLAIDLGTANTLIYAPGRGIILNEPTVVAIRHSGSQKIVAAVGLDAKQMLGRTPANISAIRPMKDGVIADFEVTET
MLNQFIGKVHEKRLFPPAPRVVVCVPCKSTLVERRAIREAVFNAGARDVRLIEEPMAAAIGAGMPVEQACGSMVVDVGGG
TTEIAIISLQGCVYADSLRIGGDVFDEQIINYVRKAHGCVIGETTAEIIKKEVGMAVSDGTTLEIEVRGRNLAEGVPRAI
TVTSDEITQAISDPLQSIVSAVKSALEQTPPELSSDIAERGIVLTGGGALLRNLDKLLAQETGLPVVVAEDPLTCVTRGG
GKVLEFFDNPNHDMLFVG

Sequences:

>Translated_338_residues
MFSPDLAIDLGTANTLIYAPGRGIILNEPTVVAIRHSGSQKIVAAVGLDAKQMLGRTPANISAIRPMKDGVIADFEVTET
MLNQFIGKVHEKRLFPPAPRVVVCVPCKSTLVERRAIREAVFNAGARDVRLIEEPMAAAIGAGMPVEQACGSMVVDVGGG
TTEIAIISLQGCVYADSLRIGGDVFDEQIINYVRKAHGCVIGETTAEIIKKEVGMAVSDGTTLEIEVRGRNLAEGVPRAI
TVTSDEITQAISDPLQSIVSAVKSALEQTPPELSSDIAERGIVLTGGGALLRNLDKLLAQETGLPVVVAEDPLTCVTRGG
GKVLEFFDNPNHDMLFVG
>Mature_338_residues
MFSPDLAIDLGTANTLIYAPGRGIILNEPTVVAIRHSGSQKIVAAVGLDAKQMLGRTPANISAIRPMKDGVIADFEVTET
MLNQFIGKVHEKRLFPPAPRVVVCVPCKSTLVERRAIREAVFNAGARDVRLIEEPMAAAIGAGMPVEQACGSMVVDVGGG
TTEIAIISLQGCVYADSLRIGGDVFDEQIINYVRKAHGCVIGETTAEIIKKEVGMAVSDGTTLEIEVRGRNLAEGVPRAI
TVTSDEITQAISDPLQSIVSAVKSALEQTPPELSSDIAERGIVLTGGGALLRNLDKLLAQETGLPVVVAEDPLTCVTRGG
GKVLEFFDNPNHDMLFVG

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=355, Percent_Identity=25.3521126760563, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI48928056, Length=172, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI24234686, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI87082236, Length=337, Percent_Identity=69.4362017804154, Blast_Score=460, Evalue=1e-131,
Organism=Escherichia coli, GI1788875, Length=389, Percent_Identity=23.6503856041131, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17568549, Length=304, Percent_Identity=25.3289473684211, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322426, Length=226, Percent_Identity=24.7787610619469, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319396, Length=218, Percent_Identity=27.0642201834862, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 35749; Mature: 35749

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSPDLAIDLGTANTLIYAPGRGIILNEPTVVAIRHSGSQKIVAAVGLDAKQMLGRTPAN
CCCCCEEEEECCCCEEEEECCCEEEECCCEEEEEEECCCCEEEEEECCCHHHHHCCCCCC
ISAIRPMKDGVIADFEVTETMLNQFIGKVHEKRLFPPAPRVVVCVPCKSTLVERRAIREA
CEEECCCCCCCEECHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHH
VFNAGARDVRLIEEPMAAAIGAGMPVEQACGSMVVDVGGGTTEIAIISLQGCVYADSLRI
HHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCEEEECCCCCEEEEEEEECCEEEECCEEC
GGDVFDEQIINYVRKAHGCVIGETTAEIIKKEVGMAVSDGTTLEIEVRGRNLAEGVPRAI
CCHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCCEECCCCEEEEEECCCCHHCCCCCEE
TVTSDEITQAISDPLQSIVSAVKSALEQTPPELSSDIAERGIVLTGGGALLRNLDKLLAQ
EEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHH
ETGLPVVVAEDPLTCVTRGGGKVLEFFDNPNHDMLFVG
HCCCEEEEECCCCEEEECCCCEEEEECCCCCCCEEEEC
>Mature Secondary Structure
MFSPDLAIDLGTANTLIYAPGRGIILNEPTVVAIRHSGSQKIVAAVGLDAKQMLGRTPAN
CCCCCEEEEECCCCEEEEECCCEEEECCCEEEEEEECCCCEEEEEECCCHHHHHCCCCCC
ISAIRPMKDGVIADFEVTETMLNQFIGKVHEKRLFPPAPRVVVCVPCKSTLVERRAIREA
CEEECCCCCCCEECHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHH
VFNAGARDVRLIEEPMAAAIGAGMPVEQACGSMVVDVGGGTTEIAIISLQGCVYADSLRI
HHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCEEEECCCCCEEEEEEEECCEEEECCEEC
GGDVFDEQIINYVRKAHGCVIGETTAEIIKKEVGMAVSDGTTLEIEVRGRNLAEGVPRAI
CCHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCCEECCCCEEEEEECCCCHHCCCCCEE
TVTSDEITQAISDPLQSIVSAVKSALEQTPPELSSDIAERGIVLTGGGALLRNLDKLLAQ
EEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHH
ETGLPVVVAEDPLTCVTRGGGKVLEFFDNPNHDMLFVG
HCCCEEEEECCCCEEEECCCCEEEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]