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The map label for this gene is hchA [H]

Identifier: 213157784

GI number: 213157784

Start: 3364689

End: 3365564

Strand: Reverse

Name: hchA [H]

Synonym: AB57_3265

Alternate gene names: 213157784

Gene position: 3365564-3364689 (Counterclockwise)

Preceding gene: 213157785

Following gene: 213157771

Centisome position: 83.09

GC content: 38.81

Gene sequence:

>876_bases
ATGAATACCCCAGCATCAAATGATAAAAATCCAACTCCAGATTTGGCTGAAGATAATGCCTTTTTCCCATCACCTTATTC
ACTGAGTCAATATACTTCTCCTAAAACAGATTACGATGGTACAACCTATCCAACGCCGTATGCAGGCAATAAAAAGGTCT
TAATGATTGCAACTGATGAACGCTATATCCAGATGCAAAACGGTAAGTTCTTTTCTACCGGAAACCATCCAGTAGAAATG
CTTTTGCCAATGTTCCATTTAGATAATGCCGGATTTGAAATTGACGTTGCGACACTTTCAGGTAATCCAGCCAAACTTGA
AATGTGGGCAATGCCAAAGCAAGAACAAGTAGTATTAGATACTTTCCAGAAATATGCAGATAAATTAAAAATACCGTTAA
AACTTGCCGATATTTTAGAAAATGTAGTCGGTGAAAACTCTCCATATGCGGCTGTATTTATTCCGGGTGGGCATGGGGTA
TTAGCGAAGATTCCGCATAGCCTTGAAGTGAAGAAAGTTCTTAAATGGGCAGTTGAACAAGACAAATTTATTATTACGTT
ATGTCATGGTCCAGCTTCGTTACTGGCTGCCGCAGTAGATGAACAGCCTGAGAATTATATTTTTAAAGATTATCAAATTT
GTGTATTCCCTGATTCGTTAGATAAGGGAGCGAATATTGATATTGGTTACATGCCTGGAGCTTTACCGTGGTTAGTCGGT
GAAAACCTTGAAAAACTCGGTGTGAAGATTTTGAACACTGGCATTACTGGTCAATGTCATCGAGACCGTAAATTGTTAAC
AGGCGATAGTCCACTTGCTTCTAATAATTTAGGCAAACTTGCAGCTGAAACATTGCTGGCTGAAGTGAAGGATTAA

Upstream 100 bases:

>100_bases
GCTTGTTGCACCTGTTTCTTGATCTGAATATACATTTAATAAGAAATAATAACTGTCTTAAAGCTGTTATTTCGCTCTTC
AATTCTAAAGGATGGTAACC

Downstream 100 bases:

>100_bases
TTCACTAAAAGTGTGCGCCCTGCGGGACTCGAATTTAATAGTTAAAATTAGGTTTTATTTAGTTATTTTATTTTTAATTA
TTTTTGATACCGTAACTCGT

Product: chaperone protein HchA

Products: NA

Alternate protein names: Hsp31 [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNTPASNDKNPTPDLAEDNAFFPSPYSLSQYTSPKTDYDGTTYPTPYAGNKKVLMIATDERYIQMQNGKFFSTGNHPVEM
LLPMFHLDNAGFEIDVATLSGNPAKLEMWAMPKQEQVVLDTFQKYADKLKIPLKLADILENVVGENSPYAAVFIPGGHGV
LAKIPHSLEVKKVLKWAVEQDKFIITLCHGPASLLAAAVDEQPENYIFKDYQICVFPDSLDKGANIDIGYMPGALPWLVG
ENLEKLGVKILNTGITGQCHRDRKLLTGDSPLASNNLGKLAAETLLAEVKD

Sequences:

>Translated_291_residues
MNTPASNDKNPTPDLAEDNAFFPSPYSLSQYTSPKTDYDGTTYPTPYAGNKKVLMIATDERYIQMQNGKFFSTGNHPVEM
LLPMFHLDNAGFEIDVATLSGNPAKLEMWAMPKQEQVVLDTFQKYADKLKIPLKLADILENVVGENSPYAAVFIPGGHGV
LAKIPHSLEVKKVLKWAVEQDKFIITLCHGPASLLAAAVDEQPENYIFKDYQICVFPDSLDKGANIDIGYMPGALPWLVG
ENLEKLGVKILNTGITGQCHRDRKLLTGDSPLASNNLGKLAAETLLAEVKD
>Mature_291_residues
MNTPASNDKNPTPDLAEDNAFFPSPYSLSQYTSPKTDYDGTTYPTPYAGNKKVLMIATDERYIQMQNGKFFSTGNHPVEM
LLPMFHLDNAGFEIDVATLSGNPAKLEMWAMPKQEQVVLDTFQKYADKLKIPLKLADILENVVGENSPYAAVFIPGGHGV
LAKIPHSLEVKKVLKWAVEQDKFIITLCHGPASLLAAAVDEQPENYIFKDYQICVFPDSLDKGANIDIGYMPGALPWLVG
ENLEKLGVKILNTGITGQCHRDRKLLTGDSPLASNNLGKLAAETLLAEVKD

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788278, Length=279, Percent_Identity=54.8387096774194, Blast_Score=320, Evalue=5e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017283
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 31986; Mature: 31986

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPASNDKNPTPDLAEDNAFFPSPYSLSQYTSPKTDYDGTTYPTPYAGNKKVLMIATDE
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
RYIQMQNGKFFSTGNHPVEMLLPMFHLDNAGFEIDVATLSGNPAKLEMWAMPKQEQVVLD
EEEEEECCEEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHHH
TFQKYADKLKIPLKLADILENVVGENSPYAAVFIPGGHGVLAKIPHSLEVKKVLKWAVEQ
HHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHCC
DKFIITLCHGPASLLAAAVDEQPENYIFKDYQICVFPDSLDKGANIDIGYMPGALPWLVG
CCEEEEEECCHHHHHHHHHCCCCCCCEEECEEEEEECCCCCCCCCEEEECCCCCCHHHHC
ENLEKLGVKILNTGITGQCHRDRKLLTGDSPLASNNLGKLAAETLLAEVKD
CCHHHHCEEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTPASNDKNPTPDLAEDNAFFPSPYSLSQYTSPKTDYDGTTYPTPYAGNKKVLMIATDE
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
RYIQMQNGKFFSTGNHPVEMLLPMFHLDNAGFEIDVATLSGNPAKLEMWAMPKQEQVVLD
EEEEEECCEEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHHH
TFQKYADKLKIPLKLADILENVVGENSPYAAVFIPGGHGVLAKIPHSLEVKKVLKWAVEQ
HHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHCC
DKFIITLCHGPASLLAAAVDEQPENYIFKDYQICVFPDSLDKGANIDIGYMPGALPWLVG
CCEEEEEECCHHHHHHHHHCCCCCCCEEECEEEEEECCCCCCCCCEEEECCCCCCHHHHC
ENLEKLGVKILNTGITGQCHRDRKLLTGDSPLASNNLGKLAAETLLAEVKD
CCHHHHCEEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA