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The map label for this gene is lolA [H]

Identifier: 213157671

GI number: 213157671

Start: 3273053

End: 3273748

Strand: Reverse

Name: lolA [H]

Synonym: AB57_3149

Alternate gene names: 213157671

Gene position: 3273748-3273053 (Counterclockwise)

Preceding gene: 213157672

Following gene: 213157670

Centisome position: 80.82

GC content: 40.66

Gene sequence:

>696_bases
ATGAATATGCTTCGTAAAACCATGTGTGCTATTACACTCAGCGCCTCAGTGCTTGCTCCTGTAATGAGTACTACAGCGTT
CGCTGCACCCGTAGCAGCACCGGAGCAACAGGCAATTGGGAACCTGGTAAATCAGTTATCAGGCTTACAGCGTTTGACTG
CCGATTTTGAACAGACAACGAAAGCGAATACAAAAACTGTAGCACAGAAAAAAGGCTTAAGTGCTCAGCATATGAACCAG
ACATTTAAAGGTTCAATGAAAGTTGAACGTCCGGGGAAATTTTATTGGGAAACTGTAAGTCCCTCTAAGCAAACTATTGT
AACAAGTGGAAAAACAGTCTGGATTTATGACCCTGATCTACAACAGGCTGTGCGCCAAAGCTTAGATGATCAGGTCGCTG
ATACACCGGCTTTATTGCTCTCTGGTAATACTAACCAAATCATGAAGTCTTACCGAGTAACTCAGCCAGATAAATCTAAG
TTATATTTCACATTATTCCCTAAAAAAGAAGATGGAGCTTTCCAAAGCTTAACGATTAGTTTTGGTGCCAACAAAGCACC
TACACTCATGGTATTGCAAGATTCTTTAGGTCAAACGACTTATGTTCGTTTCAAGAATGTTAAAGTAAATGCCTCAATTC
CAGCTTCAACTTTCAATTTTACGCCTCCGAAAGGTACCGATATCATTGATCAATAA

Upstream 100 bases:

>100_bases
AAAGTTTGTCGGTTAATATAAGTCTTGAATGAAGAGCTTGTTTAGCTGGATTAATTGAAAGGCTAGCAAGTTATCTTACA
GCAACTAAAAAGGTGATGAC

Downstream 100 bases:

>100_bases
GCCTGATTATTTAGAAAGCCATCTTTACGATGGCTTTCTTTTTATATATCAAGCCTAGATACATTTTTTAACCCCGTCTT
AAACTTACGCTTTGTATAGT

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNMLRKTMCAITLSASVLAPVMSTTAFAAPVAAPEQQAIGNLVNQLSGLQRLTADFEQTTKANTKTVAQKKGLSAQHMNQ
TFKGSMKVERPGKFYWETVSPSKQTIVTSGKTVWIYDPDLQQAVRQSLDDQVADTPALLLSGNTNQIMKSYRVTQPDKSK
LYFTLFPKKEDGAFQSLTISFGANKAPTLMVLQDSLGQTTYVRFKNVKVNASIPASTFNFTPPKGTDIIDQ

Sequences:

>Translated_231_residues
MNMLRKTMCAITLSASVLAPVMSTTAFAAPVAAPEQQAIGNLVNQLSGLQRLTADFEQTTKANTKTVAQKKGLSAQHMNQ
TFKGSMKVERPGKFYWETVSPSKQTIVTSGKTVWIYDPDLQQAVRQSLDDQVADTPALLLSGNTNQIMKSYRVTQPDKSK
LYFTLFPKKEDGAFQSLTISFGANKAPTLMVLQDSLGQTTYVRFKNVKVNASIPASTFNFTPPKGTDIIDQ
>Mature_231_residues
MNMLRKTMCAITLSASVLAPVMSTTAFAAPVAAPEQQAIGNLVNQLSGLQRLTADFEQTTKANTKTVAQKKGLSAQHMNQ
TFKGSMKVERPGKFYWETVSPSKQTIVTSGKTVWIYDPDLQQAVRQSLDDQVADTPALLLSGNTNQIMKSYRVTQPDKSK
LYFTLFPKKEDGAFQSLTISFGANKAPTLMVLQDSLGQTTYVRFKNVKVNASIPASTFNFTPPKGTDIIDQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

Organism=Escherichia coli, GI145693108, Length=224, Percent_Identity=25.4464285714286, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 25321; Mature: 25321

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMLRKTMCAITLSASVLAPVMSTTAFAAPVAAPEQQAIGNLVNQLSGLQRLTADFEQTT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KANTKTVAQKKGLSAQHMNQTFKGSMKVERPGKFYWETVSPSKQTIVTSGKTVWIYDPDL
CCCHHHHHHHCCCCHHHHHHHHCCCEEECCCCCEEEEECCCCCEEEEECCCEEEEECCCH
QQAVRQSLDDQVADTPALLLSGNTNQIMKSYRVTQPDKSKLYFTLFPKKEDGAFQSLTIS
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEE
FGANKAPTLMVLQDSLGQTTYVRFKNVKVNASIPASTFNFTPPKGTDIIDQ
ECCCCCCEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNMLRKTMCAITLSASVLAPVMSTTAFAAPVAAPEQQAIGNLVNQLSGLQRLTADFEQTT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KANTKTVAQKKGLSAQHMNQTFKGSMKVERPGKFYWETVSPSKQTIVTSGKTVWIYDPDL
CCCHHHHHHHCCCCHHHHHHHHCCCEEECCCCCEEEEECCCCCEEEEECCCEEEEECCCH
QQAVRQSLDDQVADTPALLLSGNTNQIMKSYRVTQPDKSKLYFTLFPKKEDGAFQSLTIS
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEE
FGANKAPTLMVLQDSLGQTTYVRFKNVKVNASIPASTFNFTPPKGTDIIDQ
ECCCCCCEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA