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The map label for this gene is pcaU [H]

Identifier: 213157520

GI number: 213157520

Start: 2294025

End: 2294837

Strand: Direct

Name: pcaU [H]

Synonym: AB57_2209

Alternate gene names: 213157520

Gene position: 2294025-2294837 (Clockwise)

Preceding gene: 213157519

Following gene: 213157540

Centisome position: 56.64

GC content: 38.25

Gene sequence:

>813_bases
ATGAGTAAAGATGAACGGATAATCCAGAATCAGGACAACAAAAAAACGATTCGTCATGAAGATTACATTGCTGGCATTGG
TAAAGGCATGGCGATTTTAGATAGCTTTAGTAGTAATCAACATCGTTTAAACATTTCTATGGCTGCCGAAAAAACCGGAC
TCACCCGAGCTGCAGCAAGACGTCATTTATTAACTCTAGAATATTTAGGTTATCTTGAGTCAGATGGTCACTATTACTAT
TTAACCCCAAAAGTTCTTAAATTTTCAGGAGCTTATTTAGGTGCAGCTCAGCTTCCGAAAGTGTCTCAACCTTTATTAAA
TCTTCTAACTAACCAAACCTCTCTCATTTATTCTGTGATGGTACTTGATGGTTATGAAGCCATTACGATTGCCCGTAGTG
CTGCCCACCAACAAACTGACCGTGTAAATCCATATGGTTTGCATTTAGGTAATCGCTTACCTGCTCATGCAACTTCGGCG
GGTAAAATTTTACTGGCACATTTAAGCCAAGAAGAACAATTGGACTGGCTCCAAAAATATCCGCTTCAACGTTTAACTAA
ATATACGCATGTCGAAAATGATAAATTTTTAGAGTTACTCAAAGAAATCCGAGAACAAGATTGGTGTTATTCACGTGAAG
AGCATGAATTAGGTGTTCATGCGCTCGCCGTACCGATTTATGGACAAGACTTTAAAGTAGTTGCTGCCTTAAACATTGTT
TCTCCAACCATGAGAACAACTGAAGAATATTTAATTCAACATATTTTACCGCTATTGCAAGAGACTGCGCGGGATTTAAG
ACAAGTTCTCTAA

Upstream 100 bases:

>100_bases
AAGGGATAATTTAAGGCATCAATTTTTGCGACATGAAATTATTAAACTTTTTCAGTAAAGCAAATTGATCTACTAAGCTT
CTATCGTACAAGGACCAGTA

Downstream 100 bases:

>100_bases
ATCTTACTTAGGCTATTTCCATAAGATTAATTTTATTTTTGCTTAGGCTATTTGGTTAAATAAAATGATCAGAATGTATG
CTTAGGCTATTTCTAAAAGT

Product: pca operon regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSKDERIIQNQDNKKTIRHEDYIAGIGKGMAILDSFSSNQHRLNISMAAEKTGLTRAAARRHLLTLEYLGYLESDGHYYY
LTPKVLKFSGAYLGAAQLPKVSQPLLNLLTNQTSLIYSVMVLDGYEAITIARSAAHQQTDRVNPYGLHLGNRLPAHATSA
GKILLAHLSQEEQLDWLQKYPLQRLTKYTHVENDKFLELLKEIREQDWCYSREEHELGVHALAVPIYGQDFKVVAALNIV
SPTMRTTEEYLIQHILPLLQETARDLRQVL

Sequences:

>Translated_270_residues
MSKDERIIQNQDNKKTIRHEDYIAGIGKGMAILDSFSSNQHRLNISMAAEKTGLTRAAARRHLLTLEYLGYLESDGHYYY
LTPKVLKFSGAYLGAAQLPKVSQPLLNLLTNQTSLIYSVMVLDGYEAITIARSAAHQQTDRVNPYGLHLGNRLPAHATSA
GKILLAHLSQEEQLDWLQKYPLQRLTKYTHVENDKFLELLKEIREQDWCYSREEHELGVHALAVPIYGQDFKVVAALNIV
SPTMRTTEEYLIQHILPLLQETARDLRQVL
>Mature_269_residues
SKDERIIQNQDNKKTIRHEDYIAGIGKGMAILDSFSSNQHRLNISMAAEKTGLTRAAARRHLLTLEYLGYLESDGHYYYL
TPKVLKFSGAYLGAAQLPKVSQPLLNLLTNQTSLIYSVMVLDGYEAITIARSAAHQQTDRVNPYGLHLGNRLPAHATSAG
KILLAHLSQEEQLDWLQKYPLQRLTKYTHVENDKFLELLKEIREQDWCYSREEHELGVHALAVPIYGQDFKVVAALNIVS
PTMRTTEEYLIQHILPLLQETARDLRQVL

Specific function: Activates transcription of the pca operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=245, Percent_Identity=27.7551020408163, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786468, Length=231, Percent_Identity=26.8398268398268, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788131, Length=260, Percent_Identity=25.3846153846154, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87082359, Length=230, Percent_Identity=25.2173913043478, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30752; Mature: 30620

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDERIIQNQDNKKTIRHEDYIAGIGKGMAILDSFSSNQHRLNISMAAEKTGLTRAAAR
CCCCCCHHHCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEEHHHHHCHHHHHHH
RHLLTLEYLGYLESDGHYYYLTPKVLKFSGAYLGAAQLPKVSQPLLNLLTNQTSLIYSVM
HHHHHHHHHHHEECCCCEEEECHHHHHHCCCCCCHHCCCCHHHHHHHHHHCCHHHHHHHH
VLDGYEAITIARSAAHQQTDRVNPYGLHLGNRLPAHATSAGKILLAHLSQEEQLDWLQKY
HHCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHC
PLQRLTKYTHVENDKFLELLKEIREQDWCYSREEHELGVHALAVPIYGQDFKVVAALNIV
CHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCEEEEEEEHHH
SPTMRTTEEYLIQHILPLLQETARDLRQVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SKDERIIQNQDNKKTIRHEDYIAGIGKGMAILDSFSSNQHRLNISMAAEKTGLTRAAAR
CCCCCHHHCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEEHHHHHCHHHHHHH
RHLLTLEYLGYLESDGHYYYLTPKVLKFSGAYLGAAQLPKVSQPLLNLLTNQTSLIYSVM
HHHHHHHHHHHEECCCCEEEECHHHHHHCCCCCCHHCCCCHHHHHHHHHHCCHHHHHHHH
VLDGYEAITIARSAAHQQTDRVNPYGLHLGNRLPAHATSAGKILLAHLSQEEQLDWLQKY
HHCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHC
PLQRLTKYTHVENDKFLELLKEIREQDWCYSREEHELGVHALAVPIYGQDFKVVAALNIV
CHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCEEEEEEEHHH
SPTMRTTEEYLIQHILPLLQETARDLRQVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515921 [H]