Click here to switch to the map view.

The map label for this gene is 213157473

Identifier: 213157473

GI number: 213157473

Start: 2243197

End: 2244216

Strand: Direct

Name: 213157473

Synonym: AB57_2162

Alternate gene names: NA

Gene position: 2243197-2244216 (Clockwise)

Preceding gene: 213157472

Following gene: 213157474

Centisome position: 55.38

GC content: 42.94

Gene sequence:

>1020_bases
ATGACTATTTCAAACACAACAGACTTGCCTGCTCCCTTAATGCCATCACAGCAACACAATGGCAAATTTAGAAATACGCG
TCCGAACCAACACAAGCCTTCTTTTGGCAAAACGCTTCAACTCATGTGGAAGTTTCTATTTAACAAACCTAAAAATACCG
TTCCAAACAGAGAAATTCCTGTTTTAAGTTTGTCAAAAGAACAGCTTTTAAGTGCGCCTGACCGTTCTCTATTTCGTTTG
GGTCACTCAACTATCCTGTTAAAACTGCAAGATGAATTTTGGTTAACTGACCCTGTTTTTTCAGAGCGTGCATCACCTTT
TCAATGGCTTGGACCAAAACGTTTCCATCAGCCCCCAATTAGTATTGCCGAATTACCACCCATTAAAGGCGTGATTTTGT
CGCATAACCACTACGACCACCTCGATTACCATGCGGTCATGCAGCTTAACGATAAAGTTGAGCACTTCTTAACACCGCTT
GGTGTGGGTGATACACTCATTAAATGGGGAATTCCAGCAGAAAAGGTTCAGCAGCTCGACTGGTGGGGTACCACACAGGT
AGATGGACTAAAATTAGTTGCTACCCCTGCCCATCATTTTTCAGGCCGTGGTATGGGTGATAGCAATGCGACACTTTGGG
CATCGTGGGTGATTATTGATAATGATTTACGTGTATTTTTTAGTGGAGATACGGGCTATTTTGACGGGTTTAAAGAAATC
GGTCTTCGTTATGGACCTTTCGATCTGACCATGTTAGAAACGGGTGCTTACGACCCCGAATGGCCTGATGTTCACATGCA
ACCAGAGCAAACTTTACAAGCTCATATCGATTTAAAAGGACGTCATTTGTTGCCTGTGCACAACGGTACTTTTGACTTGG
CACTTCATGCTTGGGACGACCCTTTTGAACGTATCGTCGCTTTGGCTCAACAAAATAATTTAGCGATTAGCACACCGCAA
ATGGGACAAATTTTGAACTTAAACGAGCCGAATGTTGAAAATTATTGGTGGCGTTCGTGA

Upstream 100 bases:

>100_bases
ATTAATGAGTGAGTAAATACTCATTTAAATAAATCTAAATAAGCACTTAGCCCAAGTACTTATTTGTACATATAGGTTTG
TTCCAATAAGGAAAAACAAA

Downstream 100 bases:

>100_bases
GTTTTTCGATAATTTTTTAAATTATTTATCCTATTAAATTTCAATTTAAAGGTATTTAAATTCAGTTATATACCCTACAT
ATCTAGCCTCAATATCGCTT

Product: zinc-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTISNTTDLPAPLMPSQQHNGKFRNTRPNQHKPSFGKTLQLMWKFLFNKPKNTVPNREIPVLSLSKEQLLSAPDRSLFRL
GHSTILLKLQDEFWLTDPVFSERASPFQWLGPKRFHQPPISIAELPPIKGVILSHNHYDHLDYHAVMQLNDKVEHFLTPL
GVGDTLIKWGIPAEKVQQLDWWGTTQVDGLKLVATPAHHFSGRGMGDSNATLWASWVIIDNDLRVFFSGDTGYFDGFKEI
GLRYGPFDLTMLETGAYDPEWPDVHMQPEQTLQAHIDLKGRHLLPVHNGTFDLALHAWDDPFERIVALAQQNNLAISTPQ
MGQILNLNEPNVENYWWRS

Sequences:

>Translated_339_residues
MTISNTTDLPAPLMPSQQHNGKFRNTRPNQHKPSFGKTLQLMWKFLFNKPKNTVPNREIPVLSLSKEQLLSAPDRSLFRL
GHSTILLKLQDEFWLTDPVFSERASPFQWLGPKRFHQPPISIAELPPIKGVILSHNHYDHLDYHAVMQLNDKVEHFLTPL
GVGDTLIKWGIPAEKVQQLDWWGTTQVDGLKLVATPAHHFSGRGMGDSNATLWASWVIIDNDLRVFFSGDTGYFDGFKEI
GLRYGPFDLTMLETGAYDPEWPDVHMQPEQTLQAHIDLKGRHLLPVHNGTFDLALHAWDDPFERIVALAQQNNLAISTPQ
MGQILNLNEPNVENYWWRS
>Mature_338_residues
TISNTTDLPAPLMPSQQHNGKFRNTRPNQHKPSFGKTLQLMWKFLFNKPKNTVPNREIPVLSLSKEQLLSAPDRSLFRLG
HSTILLKLQDEFWLTDPVFSERASPFQWLGPKRFHQPPISIAELPPIKGVILSHNHYDHLDYHAVMQLNDKVEHFLTPLG
VGDTLIKWGIPAEKVQQLDWWGTTQVDGLKLVATPAHHFSGRGMGDSNATLWASWVIIDNDLRVFFSGDTGYFDGFKEIG
LRYGPFDLTMLETGAYDPEWPDVHMQPEQTLQAHIDLKGRHLLPVHNGTFDLALHAWDDPFERIVALAQQNNLAISTPQM
GQILNLNEPNVENYWWRS

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=304, Percent_Identity=39.1447368421053, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI170932481, Length=304, Percent_Identity=39.1447368421053, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17543102, Length=285, Percent_Identity=32.9824561403509, Blast_Score=163, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI17543100, Length=285, Percent_Identity=32.9824561403509, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25148824, Length=285, Percent_Identity=32.9824561403509, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17543104, Length=289, Percent_Identity=32.5259515570934, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6325154, Length=241, Percent_Identity=35.2697095435685, Blast_Score=122, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38746; Mature: 38614

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISNTTDLPAPLMPSQQHNGKFRNTRPNQHKPSFGKTLQLMWKFLFNKPKNTVPNREIP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
VLSLSKEQLLSAPDRSLFRLGHSTILLKLQDEFWLTDPVFSERASPFQWLGPKRFHQPPI
EEECCHHHHHCCCCHHHHHCCCEEEEEEEECCEEECCCHHHHCCCCHHHCCCHHCCCCCC
SIAELPPIKGVILSHNHYDHLDYHAVMQLNDKVEHFLTPLGVGDTLIKWGIPAEKVQQLD
CHHCCCCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHCCCCCCCHHEECCCCHHHHHHCC
WWGTTQVDGLKLVATPAHHFSGRGMGDSNATLWASWVIIDNDLRVFFSGDTGYFDGFKEI
CCCCCCCCCEEEEEECCHHCCCCCCCCCCCEEEEEEEEEECCEEEEECCCCCHHCCHHHH
GLRYGPFDLTMLETGAYDPEWPDVHMQPEQTLQAHIDLKGRHLLPVHNGTFDLALHAWDD
CCEECCEEEEEEECCCCCCCCCCCCCCHHHHHEEEEEECCCEEEEEECCEEEEEEECCCC
PFERIVALAQQNNLAISTPQMGQILNLNEPNVENYWWRS
HHHHHHHHHHCCCEEEECCCCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TISNTTDLPAPLMPSQQHNGKFRNTRPNQHKPSFGKTLQLMWKFLFNKPKNTVPNREIP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
VLSLSKEQLLSAPDRSLFRLGHSTILLKLQDEFWLTDPVFSERASPFQWLGPKRFHQPPI
EEECCHHHHHCCCCHHHHHCCCEEEEEEEECCEEECCCHHHHCCCCHHHCCCHHCCCCCC
SIAELPPIKGVILSHNHYDHLDYHAVMQLNDKVEHFLTPLGVGDTLIKWGIPAEKVQQLD
CHHCCCCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHCCCCCCCHHEECCCCHHHHHHCC
WWGTTQVDGLKLVATPAHHFSGRGMGDSNATLWASWVIIDNDLRVFFSGDTGYFDGFKEI
CCCCCCCCCEEEEEECCHHCCCCCCCCCCCEEEEEEEEEECCEEEEECCCCCHHCCHHHH
GLRYGPFDLTMLETGAYDPEWPDVHMQPEQTLQAHIDLKGRHLLPVHNGTFDLALHAWDD
CCEECCEEEEEEECCCCCCCCCCCCCCHHHHHEEEEEECCCEEEEEECCEEEEEEECCCC
PFERIVALAQQNNLAISTPQMGQILNLNEPNVENYWWRS
HHHHHHHHHHCCCEEEECCCCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]