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The map label for this gene is yhcA [H]

Identifier: 213157188

GI number: 213157188

Start: 1960149

End: 1961588

Strand: Direct

Name: yhcA [H]

Synonym: AB57_1871

Alternate gene names: 213157188

Gene position: 1960149-1961588 (Clockwise)

Preceding gene: 213157187

Following gene: 213157189

Centisome position: 48.39

GC content: 40.42

Gene sequence:

>1440_bases
ATGGAACGTTCTTCTGTGTCCGCGGCTCAACCTCATGAGCAAAGTTTACAACGCTACGTACTTCTGACAGTTATGCTTGG
TACAGGTACGGTTAGTTTAAATAACAGTAGTTTCAACCCTGCAATACCTCATTTAATGTCCTATTTTCAGGTAGGTGAGG
TATGGGCAAGTTGGGTCGTTGTTGCCTTTTTATTAGCAATGAGTATCAGTTTGCCTTTAGCTGGATTCCTAAGCCAGCGT
TTTGGTAAGCGGTCAATTTATTTAATTGCCTTATTGGGATTTGCTTTGGCTTCTACAGCAGGTGGTTTATTTAATCAGTT
TGAATCGGTGTTGATTGCTAGAGCTCTGCAAGGCTTTTGTAGCGGATTAATGATTCCATTATCTCTTGGACTAATTTTTT
CAGTTACACCAAGTGAACAACGGGGAAGTACAACAGGATTATGGGGTGCCATGATCATGCTAACCTTAGCAGTTGGGCCT
ATGCTCGGAGCACTGGTTTTGGTATGGCTTAATTGGAAAGCCTTATTTTTTATCAATTTACCTGTTGCTTGTCTGGCATT
AATTTTAGGCTATGTTTTTCTACCTAAAGAGCAAGGGGACAATAAGCAAGAGTTTGACTGGGCAGGATTCTTTTTTCTCG
GTTCAAGCATAGTTTTATTACTTGGGACACTGAGCCAAATCCATCAAATTCAGGACTTATTTCAACCTCTATATGGTGCG
CTTTTAGTTCTAAGTGTGCTGCTTTTTATAAGGTTTATTTTTTTACAAAAGAATAAGTCGATGCCATTAATCGAGCCAGC
TTTGTTTGCTACGAAGGGTTTCCGCTACAGCTTAGTCATTTGTGTGGCACAAACAGTAGGCTTATTTATTGGCATGTTGC
TCATTCCACTATGGATACAGCACCTTCTAAAGTTAAGCCCGCTTTGGACTGGTTTTGCGCTAATGAGCAGTGCAGTAGTT
ACCGGTATTTGTAGTCAACCTGCAGGAAAATATCTAGATCGTTACGGTGCTGCAAAAATCATGTCTCTTGGACTAATGAT
TACTGTGGCTTCTTTTCTTTTGCTTGCTTGGGCACCTGTACAAAATGTCTGGTTCATTGTGTTTTGTATGATATTACATG
GCTTAGGAATGGGACTTTCTTATATGCCATCGACTACGGCAGGTTTGAACAGCTTACGCCAGCAGCAACAGCATCTAGTT
ACTCAAGCGGCCGCTCTAAATAATTTATTCCGACGTATTTTTGCTGCAGTGGCAGTCGTTATTGCCGCGTTATATCTTCA
GCTAAGACAACAATCATTGCCGTTAAATACTCAAGCAATATTTACATCATTTCACACTATGCAGGAAATCTTTGTGTGTT
GTGCAATTCTTATACTTTGCACTTTGCCTTTCGCATGGCGTTTTCCTGAACAGTACAGAATCGACCAATTAAAGAAATAG

Upstream 100 bases:

>100_bases
CCTTAAATAAATCAGGGCCAATGCATCATTCTGCTTTGGGAGCGTATGCACGAAGTAAATTATCTGAGCATATTGAATAA
GCTGAACAGAGGATATGTGT

Downstream 100 bases:

>100_bases
GATTAATAAAAATGGGACAATTACATCCAGTTTTATCAAATACACATGTGATTCAAAATGCTTTACAGGCTTGGCAGCAT
CCAAATTCGGATCAGGCAAA

Product: transporter, major facilitator family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MERSSVSAAQPHEQSLQRYVLLTVMLGTGTVSLNNSSFNPAIPHLMSYFQVGEVWASWVVVAFLLAMSISLPLAGFLSQR
FGKRSIYLIALLGFALASTAGGLFNQFESVLIARALQGFCSGLMIPLSLGLIFSVTPSEQRGSTTGLWGAMIMLTLAVGP
MLGALVLVWLNWKALFFINLPVACLALILGYVFLPKEQGDNKQEFDWAGFFFLGSSIVLLLGTLSQIHQIQDLFQPLYGA
LLVLSVLLFIRFIFLQKNKSMPLIEPALFATKGFRYSLVICVAQTVGLFIGMLLIPLWIQHLLKLSPLWTGFALMSSAVV
TGICSQPAGKYLDRYGAAKIMSLGLMITVASFLLLAWAPVQNVWFIVFCMILHGLGMGLSYMPSTTAGLNSLRQQQQHLV
TQAAALNNLFRRIFAAVAVVIAALYLQLRQQSLPLNTQAIFTSFHTMQEIFVCCAILILCTLPFAWRFPEQYRIDQLKK

Sequences:

>Translated_479_residues
MERSSVSAAQPHEQSLQRYVLLTVMLGTGTVSLNNSSFNPAIPHLMSYFQVGEVWASWVVVAFLLAMSISLPLAGFLSQR
FGKRSIYLIALLGFALASTAGGLFNQFESVLIARALQGFCSGLMIPLSLGLIFSVTPSEQRGSTTGLWGAMIMLTLAVGP
MLGALVLVWLNWKALFFINLPVACLALILGYVFLPKEQGDNKQEFDWAGFFFLGSSIVLLLGTLSQIHQIQDLFQPLYGA
LLVLSVLLFIRFIFLQKNKSMPLIEPALFATKGFRYSLVICVAQTVGLFIGMLLIPLWIQHLLKLSPLWTGFALMSSAVV
TGICSQPAGKYLDRYGAAKIMSLGLMITVASFLLLAWAPVQNVWFIVFCMILHGLGMGLSYMPSTTAGLNSLRQQQQHLV
TQAAALNNLFRRIFAAVAVVIAALYLQLRQQSLPLNTQAIFTSFHTMQEIFVCCAILILCTLPFAWRFPEQYRIDQLKK
>Mature_479_residues
MERSSVSAAQPHEQSLQRYVLLTVMLGTGTVSLNNSSFNPAIPHLMSYFQVGEVWASWVVVAFLLAMSISLPLAGFLSQR
FGKRSIYLIALLGFALASTAGGLFNQFESVLIARALQGFCSGLMIPLSLGLIFSVTPSEQRGSTTGLWGAMIMLTLAVGP
MLGALVLVWLNWKALFFINLPVACLALILGYVFLPKEQGDNKQEFDWAGFFFLGSSIVLLLGTLSQIHQIQDLFQPLYGA
LLVLSVLLFIRFIFLQKNKSMPLIEPALFATKGFRYSLVICVAQTVGLFIGMLLIPLWIQHLLKLSPLWTGFALMSSAVV
TGICSQPAGKYLDRYGAAKIMSLGLMITVASFLLLAWAPVQNVWFIVFCMILHGLGMGLSYMPSTTAGLNSLRQQQQHLV
TQAAALNNLFRRIFAAVAVVIAALYLQLRQQSLPLNTQAIFTSFHTMQEIFVCCAILILCTLPFAWRFPEQYRIDQLKK

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=386, Percent_Identity=29.7927461139896, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789042, Length=441, Percent_Identity=22.4489795918367, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788710, Length=404, Percent_Identity=21.5346534653465, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790195, Length=372, Percent_Identity=23.6559139784946, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788392, Length=431, Percent_Identity=24.1299303944316, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324264, Length=168, Percent_Identity=26.1904761904762, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 52871; Mature: 52871

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSSVSAAQPHEQSLQRYVLLTVMLGTGTVSLNNSSFNPAIPHLMSYFQVGEVWASWVV
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
VAFLLAMSISLPLAGFLSQRFGKRSIYLIALLGFALASTAGGLFNQFESVLIARALQGFC
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGLMIPLSLGLIFSVTPSEQRGSTTGLWGAMIMLTLAVGPMLGALVLVWLNWKALFFINL
HHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
PVACLALILGYVFLPKEQGDNKQEFDWAGFFFLGSSIVLLLGTLSQIHQIQDLFQPLYGA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVLSVLLFIRFIFLQKNKSMPLIEPALFATKGFRYSLVICVAQTVGLFIGMLLIPLWIQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HLLKLSPLWTGFALMSSAVVTGICSQPAGKYLDRYGAAKIMSLGLMITVASFLLLAWAPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNVWFIVFCMILHGLGMGLSYMPSTTAGLNSLRQQQQHLVTQAAALNNLFRRIFAAVAVV
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAALYLQLRQQSLPLNTQAIFTSFHTMQEIFVCCAILILCTLPFAWRFPEQYRIDQLKK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MERSSVSAAQPHEQSLQRYVLLTVMLGTGTVSLNNSSFNPAIPHLMSYFQVGEVWASWVV
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
VAFLLAMSISLPLAGFLSQRFGKRSIYLIALLGFALASTAGGLFNQFESVLIARALQGFC
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGLMIPLSLGLIFSVTPSEQRGSTTGLWGAMIMLTLAVGPMLGALVLVWLNWKALFFINL
HHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
PVACLALILGYVFLPKEQGDNKQEFDWAGFFFLGSSIVLLLGTLSQIHQIQDLFQPLYGA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVLSVLLFIRFIFLQKNKSMPLIEPALFATKGFRYSLVICVAQTVGLFIGMLLIPLWIQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HLLKLSPLWTGFALMSSAVVTGICSQPAGKYLDRYGAAKIMSLGLMITVASFLLLAWAPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNVWFIVFCMILHGLGMGLSYMPSTTAGLNSLRQQQQHLVTQAAALNNLFRRIFAAVAVV
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAALYLQLRQQSLPLNTQAIFTSFHTMQEIFVCCAILILCTLPFAWRFPEQYRIDQLKK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8969498 [H]