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The map label for this gene is appC [H]

Identifier: 213157153

GI number: 213157153

Start: 1923625

End: 1924767

Strand: Direct

Name: appC [H]

Synonym: AB57_1836

Alternate gene names: 213157153

Gene position: 1923625-1924767 (Clockwise)

Preceding gene: 213157152

Following gene: 213157154

Centisome position: 47.49

GC content: 40.33

Gene sequence:

>1143_bases
ATGCTGAGTGTTTTATCAAAAAGAAAGTTAGAAACCCAGACAGCTCCTGCTTCAGCGGGGCTATGGCGACTTGCCATGCG
TCGCCTTCGGGCCGATAAAATTGCAATGGCATCGCTCATTGTTGTGTTGTTCTATTTGATCGTATTAATACTATCTCTAA
CGGGTGTGATTGCATCTGATTGGAATAAAGAAGTTGCTGTCAGTTATGCGCCTCCTACATTTATAGGTGCAGATAAGACA
ACTGAAGCTTTGAAAAGTACAGCCGCTGTAGATGAGGAATTACCGGAAAATCCAGTCGATCCCTTAAAAGATGTAATTCA
CCAACTCAAGGCTGAAATCAAACAAGAAAAGAGCTCTGGAAGTGCAATTGATTATTATGGTGTAGTTGATCCATTAGCTG
ATGATATGAAAGCAATTGATCAGCAACTCGGTGGACATTTACTTGATCAGCAAAGTGAACTAAAAAGTACCCTAATTTTT
GGTGCTGACAAATGGGGACAAGATGTCCTTAAAAAAACCATTAAAGGCGCTGAAACTTCAATTATTGTAGGGCTTGTTTC
TGCCTTACTGGCAGTCACATTAGGAACGCTTTTAGGGGCAATTTCAGGTTATTTTGGTGGTTGGGTCGATGATATTCTCA
ACTGGTTTTATAATATTTTTACTTCCATTCCATATTTATTATTAGTTCTTGCGATTGCTGCTGTACTACAACAAAAGGGC
ATTTTATCTATTGTTCTGATTTTAGGCTTAACGGGCTGGACAGGTGTCTATCGGTTAATTCGTGCTGAATATATGAAACA
TACGGCACGCGAATATGTACTTGCAGCTAAAGCCATTGGTGTCGGGCATTTACGCCGTATGTTTATTCATATTTTTCCTA
ACGTCAGCCATATTGCATTGGTCCAAATGTCTATTTTGGTGGTTTCTTTTATTAAATCGGAAGTGATTTTGAGTTTCTTA
GGGTTCGGTGTGCCAGTAGGTGTAGTGTCTTGGGGCAGTATGTTAAATGAAGCACAAAGTGAACTTCTTTTAGGTAAGTG
GTGGCAGCTTGTCGCAGCCTCTGTCGCAATGGCGGTTTTGGTTACGGCATTTTCAATGTTTACTGATGCGCTACGCGATG
CATTAGACCCGAAACTAAAATAA

Upstream 100 bases:

>100_bases
ATTACTGTATATATTGCAGCTGCAACCATGATTTTTAATTTGATTGCGGACTTGGTCTACAAAGTGGTTGATCCACGTGT
ACAGTTGAAGTAGGTGGGTT

Downstream 100 bases:

>100_bases
AAGGAAATCCAAATGTCAGAACAAGAAAAAAAGACCCCATTACTCCACATTGAAAACTTACGTGTAAGCTTTAAAGGTGA
AGATAAACAGTATATCGAAA

Product: ABC-type dipeptide/oligopeptide/nickel transport system permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MLSVLSKRKLETQTAPASAGLWRLAMRRLRADKIAMASLIVVLFYLIVLILSLTGVIASDWNKEVAVSYAPPTFIGADKT
TEALKSTAAVDEELPENPVDPLKDVIHQLKAEIKQEKSSGSAIDYYGVVDPLADDMKAIDQQLGGHLLDQQSELKSTLIF
GADKWGQDVLKKTIKGAETSIIVGLVSALLAVTLGTLLGAISGYFGGWVDDILNWFYNIFTSIPYLLLVLAIAAVLQQKG
ILSIVLILGLTGWTGVYRLIRAEYMKHTAREYVLAAKAIGVGHLRRMFIHIFPNVSHIALVQMSILVVSFIKSEVILSFL
GFGVPVGVVSWGSMLNEAQSELLLGKWWQLVAASVAMAVLVTAFSMFTDALRDALDPKLK

Sequences:

>Translated_380_residues
MLSVLSKRKLETQTAPASAGLWRLAMRRLRADKIAMASLIVVLFYLIVLILSLTGVIASDWNKEVAVSYAPPTFIGADKT
TEALKSTAAVDEELPENPVDPLKDVIHQLKAEIKQEKSSGSAIDYYGVVDPLADDMKAIDQQLGGHLLDQQSELKSTLIF
GADKWGQDVLKKTIKGAETSIIVGLVSALLAVTLGTLLGAISGYFGGWVDDILNWFYNIFTSIPYLLLVLAIAAVLQQKG
ILSIVLILGLTGWTGVYRLIRAEYMKHTAREYVLAAKAIGVGHLRRMFIHIFPNVSHIALVQMSILVVSFIKSEVILSFL
GFGVPVGVVSWGSMLNEAQSELLLGKWWQLVAASVAMAVLVTAFSMFTDALRDALDPKLK
>Mature_380_residues
MLSVLSKRKLETQTAPASAGLWRLAMRRLRADKIAMASLIVVLFYLIVLILSLTGVIASDWNKEVAVSYAPPTFIGADKT
TEALKSTAAVDEELPENPVDPLKDVIHQLKAEIKQEKSSGSAIDYYGVVDPLADDMKAIDQQLGGHLLDQQSELKSTLIF
GADKWGQDVLKKTIKGAETSIIVGLVSALLAVTLGTLLGAISGYFGGWVDDILNWFYNIFTSIPYLLLVLAIAAVLQQKG
ILSIVLILGLTGWTGVYRLIRAEYMKHTAREYVLAAKAIGVGHLRRMFIHIFPNVSHIALVQMSILVVSFIKSEVILSFL
GFGVPVGVVSWGSMLNEAQSELLLGKWWQLVAASVAMAVLVTAFSMFTDALRDALDPKLK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=223, Percent_Identity=31.390134529148, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=31.1926605504587, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789964, Length=226, Percent_Identity=37.6106194690265, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787498, Length=232, Percent_Identity=34.051724137931, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787760, Length=219, Percent_Identity=31.9634703196347, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789889, Length=219, Percent_Identity=29.2237442922374, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787549, Length=247, Percent_Identity=27.1255060728745, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 41411; Mature: 41411

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVLSKRKLETQTAPASAGLWRLAMRRLRADKIAMASLIVVLFYLIVLILSLTGVIASD
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WNKEVAVSYAPPTFIGADKTTEALKSTAAVDEELPENPVDPLKDVIHQLKAEIKQEKSSG
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
SAIDYYGVVDPLADDMKAIDQQLGGHLLDQQSELKSTLIFGADKWGQDVLKKTIKGAETS
CCEEECCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHH
IIVGLVSALLAVTLGTLLGAISGYFGGWVDDILNWFYNIFTSIPYLLLVLAIAAVLQQKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ILSIVLILGLTGWTGVYRLIRAEYMKHTAREYVLAAKAIGVGHLRRMFIHIFPNVSHIAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VQMSILVVSFIKSEVILSFLGFGVPVGVVSWGSMLNEAQSELLLGKWWQLVAASVAMAVL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTAFSMFTDALRDALDPKLK
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLSVLSKRKLETQTAPASAGLWRLAMRRLRADKIAMASLIVVLFYLIVLILSLTGVIASD
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WNKEVAVSYAPPTFIGADKTTEALKSTAAVDEELPENPVDPLKDVIHQLKAEIKQEKSSG
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
SAIDYYGVVDPLADDMKAIDQQLGGHLLDQQSELKSTLIFGADKWGQDVLKKTIKGAETS
CCEEECCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHH
IIVGLVSALLAVTLGTLLGAISGYFGGWVDDILNWFYNIFTSIPYLLLVLAIAAVLQQKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ILSIVLILGLTGWTGVYRLIRAEYMKHTAREYVLAAKAIGVGHLRRMFIHIFPNVSHIAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VQMSILVVSFIKSEVILSFLGFGVPVGVVSWGSMLNEAQSELLLGKWWQLVAASVAMAVL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTAFSMFTDALRDALDPKLK
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]