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The map label for this gene is glcB [H]

Identifier: 213157142

GI number: 213157142

Start: 1908427

End: 1910592

Strand: Direct

Name: glcB [H]

Synonym: AB57_1825

Alternate gene names: 213157142

Gene position: 1908427-1910592 (Clockwise)

Preceding gene: 213157141

Following gene: 213157143

Centisome position: 47.12

GC content: 38.69

Gene sequence:

>2166_bases
ATGACTGCACGTATTCAAAAAGGCAAGTTAGCGATTGCTAAAGAACTTTACGATTTTATCGAAAATGAAGCTTTACCAGG
TTCTGGTTTAGATAGTGAAACTTACTGGAAGAACTTTGAGCAAGTTGTTGTCGACCTTAGTCCAAAGAATAAAGCATTAT
TGGCTAAGCGTGATGAATTACAAGCAAAAATTGATGAATGGCACCGCAACAATAAATTTGAATTAGGTGCTTACAAAGCA
TTTTTAACTGAAATTGGTTATTTATTACCAGAAGTTGAAGACTTCCAAATTACTACTGAAAACGTAGATGAAGAAATTGC
ATTGTTAGCAGGCCCACAATTAGTAGTACCTGTACGTAATGCACGTTATTGCTTAAATGCAGCAAATGCACGCTGGGGTT
CTTTGTACGATGCACTTTACGGCTTCGATGTAATTTCAGAAGAAGGCGGTGCAGAAAAAGGAAAAGGATATAACCCTGTA
CGTGGTGCGAAAGTTATTGAGTTTGCTAAAAACTTCTTAAATGAAATTTTCCCGCTTGCGCAAGGCTCACATGCTGATGC
AACTAAATATGCAATCGAGCAGAATAAACTCGTTGTGACTTTAAAAGATGGTACTAAAACTGGCTTAGCTCATGAAGCTC
AGTTTGTGGGTTTCAATGGTGAAGAAGCGAACCCTTCAGAAGTTGTTCTTTTGAGTAATGGCTTACATGTCATTATTGAA
ATTGATGCGAATAGCCCAATTGGCCAAACTGATTTAGCGGGTGTTAAAGATCTAACACTTGAAGCTGCGGTTACAACAAT
TCAGGATCTTGAAGACTCTGTAGCAGCTGTTGATGCAGAAGAAAAGGTTGAAGGTTATCGTAACTGGTTAGGTTTGATGA
AGGGCACTCTTCAAGAATCTATCGAAAAAAATGGTAAAACAATTGTTCGCGCTTTGAATAAAGACCGTGAAATTAAAAAT
TTGATCGGTGGCACAACAAAACTTCATGGTCGTTCACTTATGTTACTTCGTAACGTAGGTCATTTAATGACGAATCCAGC
GATATTAGTTGATGGTGAAGAAATTTTCGAAGGTATTATGGATGCGTTGGTAACGCCATTGTTATCAATTGCTGACATCC
GTAGTGAAAACGAAAATAAAAACTCTCGTAAAGGGTCTATGTATATTGTTAAACCAAAAATGCATGGCCCTGAAGAAGTT
GCTTTTGCTGTTGAGTTATTTGAGCGTGCTGAGCAAGCCTTAGGATTACCAGCGAAGTCTTTAAAAATCGGTATTATGGA
TGAAGAACGCCGTACATCTGTAAACTTGAAAAACTGTATTGCTGCTGCTAAAGATCGCACAATCTTTATTAACACTGGGT
TCATGGACCGTACTGGTGATGAAATCCATACTTCTATGGAAGCTGCTCCAGTTGTTCGTAAAGAAGCGGTTAAAACACAA
AAATGGATTGCTGCTTACGAAAACCGTAACGTTGCAATCGGTTTGAAATGTGGTTTACAAGGTAAAGCACAGATTGGTAA
AGGCATGTGGCCAAAACCAGATAGCATGAAAGATATGTTGGCAACTAAAGCTGCTCATCCAAATGCTGGTGCTTCATGTG
CTTGGGTTCCATCACCAACTGGTGCTGTACTTCATGCGATGCATTACCATCAAGTAAATGTAAAAGCACGTCAAGATCAG
TTAAAAGCTGAAGAAATGTTGTCATTAGATGACTTGTTAACTCCTCCATTTGCAACTGATACAAACTGGTCAGCAGAAGA
AATTAATAACGAGCTCGAAAATAACTGCCAAGGTATTTTAGGTTACGTTGTGCGTTGGGTTGACTTAGGTGTAGGTTGTT
CAAAAGTTCCTGATATTAACAACGTGGGCTTAATGGAAGACCGTGCAACATTACGTATTTCTTCTCAACATGTTGCCAAC
TGGTTACGTCACGGTATCGTGACTCGTGAACAAGTTGAAGAAGTGCTTAAACGCATGGCAAAAATTGTTGATGAACAAAA
TGCGAATGATCCATTGTATAAACCAATGGCAGCTAACTTTGAAACTAATATTGCTTTCCAAGCAGCTTCAGACCTTATCT
TTAAAGGTTGTGAACAGCCTTCTGGTTATACTGAGCCATTACTACATGCGGCTCGTTTAAAATTAAAAGGTTATACAGGT
GACTAA

Upstream 100 bases:

>100_bases
AATGCTTACTATTTAGGAATGTGATATTAGTATTCAGCTTAATTTAAATCGGTATACTAGGATTCTCTTGGTATAAAAAG
TAGCAACTTCAGGAAAGACA

Downstream 100 bases:

>100_bases
TTTTAACCTGTTATAAAAAAAGCCTCTTCGGAGGCTTTTTTATTTTCGGTATATTTTGTGCTTATAGATAAGACGTGAAT
TTATAAATAAAGGATTTCAA

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 721; Mature: 720

Protein sequence:

>721_residues
MTARIQKGKLAIAKELYDFIENEALPGSGLDSETYWKNFEQVVVDLSPKNKALLAKRDELQAKIDEWHRNNKFELGAYKA
FLTEIGYLLPEVEDFQITTENVDEEIALLAGPQLVVPVRNARYCLNAANARWGSLYDALYGFDVISEEGGAEKGKGYNPV
RGAKVIEFAKNFLNEIFPLAQGSHADATKYAIEQNKLVVTLKDGTKTGLAHEAQFVGFNGEEANPSEVVLLSNGLHVIIE
IDANSPIGQTDLAGVKDLTLEAAVTTIQDLEDSVAAVDAEEKVEGYRNWLGLMKGTLQESIEKNGKTIVRALNKDREIKN
LIGGTTKLHGRSLMLLRNVGHLMTNPAILVDGEEIFEGIMDALVTPLLSIADIRSENENKNSRKGSMYIVKPKMHGPEEV
AFAVELFERAEQALGLPAKSLKIGIMDEERRTSVNLKNCIAAAKDRTIFINTGFMDRTGDEIHTSMEAAPVVRKEAVKTQ
KWIAAYENRNVAIGLKCGLQGKAQIGKGMWPKPDSMKDMLATKAAHPNAGASCAWVPSPTGAVLHAMHYHQVNVKARQDQ
LKAEEMLSLDDLLTPPFATDTNWSAEEINNELENNCQGILGYVVRWVDLGVGCSKVPDINNVGLMEDRATLRISSQHVAN
WLRHGIVTREQVEEVLKRMAKIVDEQNANDPLYKPMAANFETNIAFQAASDLIFKGCEQPSGYTEPLLHAARLKLKGYTG
D

Sequences:

>Translated_721_residues
MTARIQKGKLAIAKELYDFIENEALPGSGLDSETYWKNFEQVVVDLSPKNKALLAKRDELQAKIDEWHRNNKFELGAYKA
FLTEIGYLLPEVEDFQITTENVDEEIALLAGPQLVVPVRNARYCLNAANARWGSLYDALYGFDVISEEGGAEKGKGYNPV
RGAKVIEFAKNFLNEIFPLAQGSHADATKYAIEQNKLVVTLKDGTKTGLAHEAQFVGFNGEEANPSEVVLLSNGLHVIIE
IDANSPIGQTDLAGVKDLTLEAAVTTIQDLEDSVAAVDAEEKVEGYRNWLGLMKGTLQESIEKNGKTIVRALNKDREIKN
LIGGTTKLHGRSLMLLRNVGHLMTNPAILVDGEEIFEGIMDALVTPLLSIADIRSENENKNSRKGSMYIVKPKMHGPEEV
AFAVELFERAEQALGLPAKSLKIGIMDEERRTSVNLKNCIAAAKDRTIFINTGFMDRTGDEIHTSMEAAPVVRKEAVKTQ
KWIAAYENRNVAIGLKCGLQGKAQIGKGMWPKPDSMKDMLATKAAHPNAGASCAWVPSPTGAVLHAMHYHQVNVKARQDQ
LKAEEMLSLDDLLTPPFATDTNWSAEEINNELENNCQGILGYVVRWVDLGVGCSKVPDINNVGLMEDRATLRISSQHVAN
WLRHGIVTREQVEEVLKRMAKIVDEQNANDPLYKPMAANFETNIAFQAASDLIFKGCEQPSGYTEPLLHAARLKLKGYTG
D
>Mature_720_residues
TARIQKGKLAIAKELYDFIENEALPGSGLDSETYWKNFEQVVVDLSPKNKALLAKRDELQAKIDEWHRNNKFELGAYKAF
LTEIGYLLPEVEDFQITTENVDEEIALLAGPQLVVPVRNARYCLNAANARWGSLYDALYGFDVISEEGGAEKGKGYNPVR
GAKVIEFAKNFLNEIFPLAQGSHADATKYAIEQNKLVVTLKDGTKTGLAHEAQFVGFNGEEANPSEVVLLSNGLHVIIEI
DANSPIGQTDLAGVKDLTLEAAVTTIQDLEDSVAAVDAEEKVEGYRNWLGLMKGTLQESIEKNGKTIVRALNKDREIKNL
IGGTTKLHGRSLMLLRNVGHLMTNPAILVDGEEIFEGIMDALVTPLLSIADIRSENENKNSRKGSMYIVKPKMHGPEEVA
FAVELFERAEQALGLPAKSLKIGIMDEERRTSVNLKNCIAAAKDRTIFINTGFMDRTGDEIHTSMEAAPVVRKEAVKTQK
WIAAYENRNVAIGLKCGLQGKAQIGKGMWPKPDSMKDMLATKAAHPNAGASCAWVPSPTGAVLHAMHYHQVNVKARQDQL
KAEEMLSLDDLLTPPFATDTNWSAEEINNELENNCQGILGYVVRWVDLGVGCSKVPDINNVGLMEDRATLRISSQHVANW
LRHGIVTREQVEEVLKRMAKIVDEQNANDPLYKPMAANFETNIAFQAASDLIFKGCEQPSGYTEPLLHAARLKLKGYTGD

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=725, Percent_Identity=57.1034482758621, Blast_Score=853, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 79507; Mature: 79375

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARIQKGKLAIAKELYDFIENEALPGSGLDSETYWKNFEQVVVDLSPKNKALLAKRDEL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCCEEHHHHHHH
QAKIDEWHRNNKFELGAYKAFLTEIGYLLPEVEDFQITTENVDEEIALLAGPQLVVPVRN
HHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHEEECCEEEEEECC
ARYCLNAANARWGSLYDALYGFDVISEEGGAEKGKGYNPVRGAKVIEFAKNFLNEIFPLA
CHHHHCCCCCCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
QGSHADATKYAIEQNKLVVTLKDGTKTGLAHEAQFVGFNGEEANPSEVVLLSNGLHVIIE
CCCCCCHHHHEEECCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEE
IDANSPIGQTDLAGVKDLTLEAAVTTIQDLEDSVAAVDAEEKVEGYRNWLGLMKGTLQES
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IEKNGKTIVRALNKDREIKNLIGGTTKLHGRSLMLLRNVGHLMTNPAILVDGEEIFEGIM
HHHCCHHHHHHHHCCHHHHHHHCCCCEECCCHHHHHHHHHHHHCCCEEEECHHHHHHHHH
DALVTPLLSIADIRSENENKNSRKGSMYIVKPKMHGPEEVAFAVELFERAEQALGLPAKS
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHH
LKIGIMDEERRTSVNLKNCIAAAKDRTIFINTGFMDRTGDEIHTSMEAAPVVRKEAVKTQ
EEEEEECCHHHHCCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KWIAAYENRNVAIGLKCGLQGKAQIGKGMWPKPDSMKDMLATKAAHPNAGASCAWVPSPT
HHHHHHCCCCEEEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCC
GAVLHAMHYHQVNVKARQDQLKAEEMLSLDDLLTPPFATDTNWSAEEINNELENNCQGIL
HHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GYVVRWVDLGVGCSKVPDINNVGLMEDRATLRISSQHVANWLRHGIVTREQVEEVLKRMA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHHHHHH
KIVDEQNANDPLYKPMAANFETNIAFQAASDLIFKGCEQPSGYTEPLLHAARLKLKGYTG
HHHHCCCCCCCCCCCHHCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHEECCCCC
D
C
>Mature Secondary Structure 
TARIQKGKLAIAKELYDFIENEALPGSGLDSETYWKNFEQVVVDLSPKNKALLAKRDEL
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCCEEHHHHHHH
QAKIDEWHRNNKFELGAYKAFLTEIGYLLPEVEDFQITTENVDEEIALLAGPQLVVPVRN
HHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHEEECCEEEEEECC
ARYCLNAANARWGSLYDALYGFDVISEEGGAEKGKGYNPVRGAKVIEFAKNFLNEIFPLA
CHHHHCCCCCCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
QGSHADATKYAIEQNKLVVTLKDGTKTGLAHEAQFVGFNGEEANPSEVVLLSNGLHVIIE
CCCCCCHHHHEEECCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEE
IDANSPIGQTDLAGVKDLTLEAAVTTIQDLEDSVAAVDAEEKVEGYRNWLGLMKGTLQES
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IEKNGKTIVRALNKDREIKNLIGGTTKLHGRSLMLLRNVGHLMTNPAILVDGEEIFEGIM
HHHCCHHHHHHHHCCHHHHHHHCCCCEECCCHHHHHHHHHHHHCCCEEEECHHHHHHHHH
DALVTPLLSIADIRSENENKNSRKGSMYIVKPKMHGPEEVAFAVELFERAEQALGLPAKS
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHH
LKIGIMDEERRTSVNLKNCIAAAKDRTIFINTGFMDRTGDEIHTSMEAAPVVRKEAVKTQ
EEEEEECCHHHHCCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KWIAAYENRNVAIGLKCGLQGKAQIGKGMWPKPDSMKDMLATKAAHPNAGASCAWVPSPT
HHHHHHCCCCEEEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCC
GAVLHAMHYHQVNVKARQDQLKAEEMLSLDDLLTPPFATDTNWSAEEINNELENNCQGIL
HHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GYVVRWVDLGVGCSKVPDINNVGLMEDRATLRISSQHVANWLRHGIVTREQVEEVLKRMA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHHHHHH
KIVDEQNANDPLYKPMAANFETNIAFQAASDLIFKGCEQPSGYTEPLLHAARLKLKGYTG
HHHHCCCCCCCCCCCHHCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHEECCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]