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The map label for this gene is rhtC [H]

Identifier: 213156962

GI number: 213156962

Start: 1726103

End: 1726741

Strand: Direct

Name: rhtC [H]

Synonym: AB57_1637

Alternate gene names: 213156962

Gene position: 1726103-1726741 (Clockwise)

Preceding gene: 213156960

Following gene: 213156968

Centisome position: 42.61

GC content: 40.06

Gene sequence:

>639_bases
ATGTGGCAGTTGTATGGACATGAGTTTTTAACGCTAGCTCTTATTCACTTTATGGCGGTGATTTTACCGGGACCAGATTT
TGTGATTACGGTAAGACAAAGTGTACGTTATGGCTATTTGATTGGTTGTCTGACTGCAATTGGTATTGGTGTCGGAATTT
CAGTCCATGTGTTTTATACACTGGTTGGTATTGGCTTTTTGATTCAGCAAAGTGAATGGCTTATGTCACTGATCAGAACA
GCGGGGGCGGCTTACTTAGTGTATTTAGGATGGCAGTGCTTACGTAGCCAGCCGAATACCAATATTGAAATTAATGGCCA
ATTAGACAGTGACACGCCGAGTTTATTTAAAGCGTTTACAATGGGTTTTCTCACTAATGCGTTAAACCCCAAAGCCACCA
TCTTTTTTCTGGCAATTTTTACGACGATTGTAAGTACGACCACACCAATGAAAGTTCAGGTTTTTTATGGGGTTTGGATG
TGTATGGTCAATGCCATCTGGTTTATGGTGGTGAGTGTACTGTTTGCACAGCCTATCGTACGTAAAAGATTTTTGGAGTT
TGGGGTTTATTTTGAGAGGGTGATGGGAGTGTTATTAATTGGAATTGCATTGAGATTGATTTGGGGATTGTTTAATTAA

Upstream 100 bases:

>100_bases
TGTGCTCATGAGGCAAAAGTTATTTGGATTTTAATTGGATTATCGCGTCTAAAAAAACGCAATACAATCTTTTCTGTGAT
TTTCAGGAAACTAAATTGTT

Downstream 100 bases:

>100_bases
GTTGGATATCTATTGATATTTCCTCAGGTTAAAGTCATCTGCAAGTTTTTAGACTAGCACAACGGAGCCCATACTTGCAT
TTGCTAGTGCTAAATTTCAT

Product: lysine exporter protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MWQLYGHEFLTLALIHFMAVILPGPDFVITVRQSVRYGYLIGCLTAIGIGVGISVHVFYTLVGIGFLIQQSEWLMSLIRT
AGAAYLVYLGWQCLRSQPNTNIEINGQLDSDTPSLFKAFTMGFLTNALNPKATIFFLAIFTTIVSTTTPMKVQVFYGVWM
CMVNAIWFMVVSVLFAQPIVRKRFLEFGVYFERVMGVLLIGIALRLIWGLFN

Sequences:

>Translated_212_residues
MWQLYGHEFLTLALIHFMAVILPGPDFVITVRQSVRYGYLIGCLTAIGIGVGISVHVFYTLVGIGFLIQQSEWLMSLIRT
AGAAYLVYLGWQCLRSQPNTNIEINGQLDSDTPSLFKAFTMGFLTNALNPKATIFFLAIFTTIVSTTTPMKVQVFYGVWM
CMVNAIWFMVVSVLFAQPIVRKRFLEFGVYFERVMGVLLIGIALRLIWGLFN
>Mature_212_residues
MWQLYGHEFLTLALIHFMAVILPGPDFVITVRQSVRYGYLIGCLTAIGIGVGISVHVFYTLVGIGFLIQQSEWLMSLIRT
AGAAYLVYLGWQCLRSQPNTNIEINGQLDSDTPSLFKAFTMGFLTNALNPKATIFFLAIFTTIVSTTTPMKVQVFYGVWM
CMVNAIWFMVVSVLFAQPIVRKRFLEFGVYFERVMGVLLIGIALRLIWGLFN

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=201, Percent_Identity=28.8557213930348, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1786522, Length=186, Percent_Identity=30.1075268817204, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788099, Length=193, Percent_Identity=26.9430051813472, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23915; Mature: 23915

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQLYGHEFLTLALIHFMAVILPGPDFVITVRQSVRYGYLIGCLTAIGIGVGISVHVFYT
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LVGIGFLIQQSEWLMSLIRTAGAAYLVYLGWQCLRSQPNTNIEINGQLDSDTPSLFKAFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHH
MGFLTNALNPKATIFFLAIFTTIVSTTTPMKVQVFYGVWMCMVNAIWFMVVSVLFAQPIV
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKRFLEFGVYFERVMGVLLIGIALRLIWGLFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWQLYGHEFLTLALIHFMAVILPGPDFVITVRQSVRYGYLIGCLTAIGIGVGISVHVFYT
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LVGIGFLIQQSEWLMSLIRTAGAAYLVYLGWQCLRSQPNTNIEINGQLDSDTPSLFKAFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHH
MGFLTNALNPKATIFFLAIFTTIVSTTTPMKVQVFYGVWMCMVNAIWFMVVSVLFAQPIV
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKRFLEFGVYFERVMGVLLIGIALRLIWGLFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]