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The map label for this gene is yhcS [C]

Identifier: 213156925

GI number: 213156925

Start: 1685705

End: 1686646

Strand: Direct

Name: yhcS [C]

Synonym: AB57_1596

Alternate gene names: 213156925

Gene position: 1685705-1686646 (Clockwise)

Preceding gene: 213156923

Following gene: 213156931

Centisome position: 41.62

GC content: 43.31

Gene sequence:

>942_bases
ATGCGCAAAAATCTCGATGGTGGACTTTTGCATGCAATGCATGCATTCCTGAAAGTGATTGATAGCGGGAGTTTCACAGC
AGCAGCTGAGCAGATGGATCTGACCACAGCACAGGTTTCACGTCTTATCAGCGAGCTAGAAACACGCTTAGGTACAAAAT
TAATACAACGCTCAACGCGCCAGCAGGCACTGACTGATATTGGTGCAACTTATGCAGAGCGTTGTCGGCAAGTTATTTCA
ATGGTGGATGAAGCAGAGGCAGAAGTCACCGGAACGGCATCTAAACCTAAAGGTCGTTTACGTGTATTAAGTATGGGAAG
CTTTGGGCATCATTATGTTTTCCCTGTCATGGCCGAGTTTTGTAAGCATTATCCCGAATTAACAGTGGAATATACGACCT
CACAATACGTTCCGGACCTGTTGGCAAAAGGGGTGGATGTCAGTCTTTATCTCACTGAATCATTAACAGACTCTCGTTTT
GTTGCACGCAGAATTGGCACTATTTTTTCTGTTTTATGTGCTTCACCTGCGTACCTAGAAAAACACGGCGTTCCTAAGTC
TCCAGAAGACTTAAAAAATCATGCCTGTTTACGCTTGGTAAACCCGTCTATTACGCCAGATTGGCATTTGTTAAATGCCA
ATGGTGAGTCTTGTCAAATCGACATTGGAGGGCAACTCATTGCAGATAACCCTGAGTTATTGTTAGATGTGGTGCAACAG
GATATGGGGGTCGCGTTATTGCCGATGTTTTCGGCTTTAGACGCGGTTCAAAATGGAAGATTATGTCATATCTTGCCTGA
GTGGCGTTCGCCCGATATTGGAGTTTATACCTTATTGCCTTCACGCCATTTTATTGATGCCAAAACACGCGCATGGTTGG
ATTGGGTAGAAGAATATATTTCTCCAAGAATTGAAATGGATGCATCTTATTTTTATAAATAA

Upstream 100 bases:

>100_bases
CTTCTTAAAAAAGAATTAGTGCCAATGTATGTACATTTAGTCATTGTGGTTGATCTAAACTGGTGCAACAATCCGTAATT
TAGGAAAAGATATTTACGTT

Downstream 100 bases:

>100_bases
TGAGATAAATTTTTTAAGGATTACAAGTGAAAAAGGATGAAGAATAATACGGATTAGAATAAAAATAGGGTAGAAAATGC
TTCTTTTTAAAGAGGCATTT

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRKNLDGGLLHAMHAFLKVIDSGSFTAAAEQMDLTTAQVSRLISELETRLGTKLIQRSTRQQALTDIGATYAERCRQVIS
MVDEAEAEVTGTASKPKGRLRVLSMGSFGHHYVFPVMAEFCKHYPELTVEYTTSQYVPDLLAKGVDVSLYLTESLTDSRF
VARRIGTIFSVLCASPAYLEKHGVPKSPEDLKNHACLRLVNPSITPDWHLLNANGESCQIDIGGQLIADNPELLLDVVQQ
DMGVALLPMFSALDAVQNGRLCHILPEWRSPDIGVYTLLPSRHFIDAKTRAWLDWVEEYISPRIEMDASYFYK

Sequences:

>Translated_313_residues
MRKNLDGGLLHAMHAFLKVIDSGSFTAAAEQMDLTTAQVSRLISELETRLGTKLIQRSTRQQALTDIGATYAERCRQVIS
MVDEAEAEVTGTASKPKGRLRVLSMGSFGHHYVFPVMAEFCKHYPELTVEYTTSQYVPDLLAKGVDVSLYLTESLTDSRF
VARRIGTIFSVLCASPAYLEKHGVPKSPEDLKNHACLRLVNPSITPDWHLLNANGESCQIDIGGQLIADNPELLLDVVQQ
DMGVALLPMFSALDAVQNGRLCHILPEWRSPDIGVYTLLPSRHFIDAKTRAWLDWVEEYISPRIEMDASYFYK
>Mature_313_residues
MRKNLDGGLLHAMHAFLKVIDSGSFTAAAEQMDLTTAQVSRLISELETRLGTKLIQRSTRQQALTDIGATYAERCRQVIS
MVDEAEAEVTGTASKPKGRLRVLSMGSFGHHYVFPVMAEFCKHYPELTVEYTTSQYVPDLLAKGVDVSLYLTESLTDSRF
VARRIGTIFSVLCASPAYLEKHGVPKSPEDLKNHACLRLVNPSITPDWHLLNANGESCQIDIGGQLIADNPELLLDVVQQ
DMGVALLPMFSALDAVQNGRLCHILPEWRSPDIGVYTLLPSRHFIDAKTRAWLDWVEEYISPRIEMDASYFYK

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=30.3754266211604, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786401, Length=286, Percent_Identity=29.020979020979, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=30.4498269896194, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=28.135593220339, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789440, Length=257, Percent_Identity=28.4046692607004, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787128, Length=284, Percent_Identity=26.7605633802817, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=24.9134948096886, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789173, Length=253, Percent_Identity=28.8537549407115, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788706, Length=250, Percent_Identity=23.6, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI157672245, Length=130, Percent_Identity=28.4615384615385, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786448, Length=125, Percent_Identity=29.6, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790011, Length=268, Percent_Identity=22.7611940298507, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34960; Mature: 34960

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNLDGGLLHAMHAFLKVIDSGSFTAAAEQMDLTTAQVSRLISELETRLGTKLIQRSTR
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQALTDIGATYAERCRQVISMVDEAEAEVTGTASKPKGRLRVLSMGSFGHHYVFPVMAEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCCCCHHHHHHHHHH
CKHYPELTVEYTTSQYVPDLLAKGVDVSLYLTESLTDSRFVARRIGTIFSVLCASPAYLE
HHCCCCEEEEECHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHH
KHGVPKSPEDLKNHACLRLVNPSITPDWHLLNANGESCQIDIGGQLIADNPELLLDVVQQ
HCCCCCCHHHHHCCCEEEEECCCCCCCEEEEECCCCEEEEEECCEEEECCHHHHHHHHHH
DMGVALLPMFSALDAVQNGRLCHILPEWRSPDIGVYTLLPSRHFIDAKTRAWLDWVEEYI
HCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
SPRIEMDASYFYK
CCCEECCHHHHCC
>Mature Secondary Structure
MRKNLDGGLLHAMHAFLKVIDSGSFTAAAEQMDLTTAQVSRLISELETRLGTKLIQRSTR
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQALTDIGATYAERCRQVISMVDEAEAEVTGTASKPKGRLRVLSMGSFGHHYVFPVMAEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCCCCHHHHHHHHHH
CKHYPELTVEYTTSQYVPDLLAKGVDVSLYLTESLTDSRFVARRIGTIFSVLCASPAYLE
HHCCCCEEEEECHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHH
KHGVPKSPEDLKNHACLRLVNPSITPDWHLLNANGESCQIDIGGQLIADNPELLLDVVQQ
HCCCCCCHHHHHCCCEEEEECCCCCCCEEEEECCCCEEEEEECCEEEECCHHHHHHHHHH
DMGVALLPMFSALDAVQNGRLCHILPEWRSPDIGVYTLLPSRHFIDAKTRAWLDWVEEYI
HCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
SPRIEMDASYFYK
CCCEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]