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The map label for this gene is pcaR [H]

Identifier: 213156906

GI number: 213156906

Start: 1662081

End: 1662932

Strand: Direct

Name: pcaR [H]

Synonym: AB57_1577

Alternate gene names: 213156906

Gene position: 1662081-1662932 (Clockwise)

Preceding gene: 213156905

Following gene: 213156908

Centisome position: 41.03

GC content: 40.26

Gene sequence:

>852_bases
ATGACAATGAACGATGCAGTTGATGCAGAACAGACAGAAAAATTATTAGCGCCTTTAAGGCATGAATTATTACATCCGAT
TGAAGACATGCAGGATGAAAATGATCGCCAATTTATTACTGCATTAGCACGTGGTTTAGAGCTATTACGTTGTTTTACGC
CTAAACATCAGCATTTGGGCAATCAAGAGCTTGCGCAGATGACAGGTTTGCCAAAACCAACCATTACTCGCCTCACACAT
ACTTTGTCGCGTTTGGGCTATATCAAACAAGTACCTAACTCAAGCAAATTTCAGCTTTCAGTAGGAGTTCTTGCGTTTGG
TTATTCGATGCTGTCTAACGTATCGATTCGCTCTATTGCTCATCCATATATGAAAAATTTGGCAGACTATGCTGGCGCTG
CTGTTGCCATGGCAACACGTGATCGACTGAATATGATTTATCTTGATGTGGTGCAAGGCAAAGGCAATATGACCATGCGC
CGTCAAGTTGGAACCTATTTACCGATTCATTTAAGTTCGATGGGACGTGCGTGTTTAGCTGCAATGCCTGAAGATGAAAG
AGAGTTCTTACTTAATGCCATTCGTAACAAGCACAAAGAAGACTGGATCAAAATTAACCGTGATTTAGACAAAGCCTTTA
AAGATTACCAAGATTTTGGATACTGTTTTTCTATTGGCGAATGGCATAAAGATGTCAATTCTGTTGCTGTTCCACTCATT
CATGAACAACATGGTTTGCTGGTGTTCAACTGTGGTGGCCCAAGTTTCATTATGAATCGTGAAAAACTCGAAGAAGATAT
TGCACCGCGTCTTTTACATATGGTGAATAATATTCGCACTGAGATTAGCTAA

Upstream 100 bases:

>100_bases
GAAGTTATCTTTAAAATGCAGACTAGGATGTTTGCTCTTTTGCTATTTATTGAAAAAATAGATTATAATTTTCGCAGTGC
GAAACAAAATATGGATTGGT

Downstream 100 bases:

>100_bases
ACCTATTTGATCCATTTATAAGAGCCAGCTTTGTTTTTTCAAGGCTGGCTTTTTATTGGGTAAGCTTTAGGCTGTTTGCT
TATGGAAGTTCGGTTTCCGT

Product: transcriptional regulator, IclR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTMNDAVDAEQTEKLLAPLRHELLHPIEDMQDENDRQFITALARGLELLRCFTPKHQHLGNQELAQMTGLPKPTITRLTH
TLSRLGYIKQVPNSSKFQLSVGVLAFGYSMLSNVSIRSIAHPYMKNLADYAGAAVAMATRDRLNMIYLDVVQGKGNMTMR
RQVGTYLPIHLSSMGRACLAAMPEDEREFLLNAIRNKHKEDWIKINRDLDKAFKDYQDFGYCFSIGEWHKDVNSVAVPLI
HEQHGLLVFNCGGPSFIMNREKLEEDIAPRLLHMVNNIRTEIS

Sequences:

>Translated_283_residues
MTMNDAVDAEQTEKLLAPLRHELLHPIEDMQDENDRQFITALARGLELLRCFTPKHQHLGNQELAQMTGLPKPTITRLTH
TLSRLGYIKQVPNSSKFQLSVGVLAFGYSMLSNVSIRSIAHPYMKNLADYAGAAVAMATRDRLNMIYLDVVQGKGNMTMR
RQVGTYLPIHLSSMGRACLAAMPEDEREFLLNAIRNKHKEDWIKINRDLDKAFKDYQDFGYCFSIGEWHKDVNSVAVPLI
HEQHGLLVFNCGGPSFIMNREKLEEDIAPRLLHMVNNIRTEIS
>Mature_282_residues
TMNDAVDAEQTEKLLAPLRHELLHPIEDMQDENDRQFITALARGLELLRCFTPKHQHLGNQELAQMTGLPKPTITRLTHT
LSRLGYIKQVPNSSKFQLSVGVLAFGYSMLSNVSIRSIAHPYMKNLADYAGAAVAMATRDRLNMIYLDVVQGKGNMTMRR
QVGTYLPIHLSSMGRACLAAMPEDEREFLLNAIRNKHKEDWIKINRDLDKAFKDYQDFGYCFSIGEWHKDVNSVAVPLIH
EQHGLLVFNCGGPSFIMNREKLEEDIAPRLLHMVNNIRTEIS

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=156, Percent_Identity=32.6923076923077, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786468, Length=203, Percent_Identity=25.1231527093596, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788131, Length=222, Percent_Identity=23.4234234234234, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI145693096, Length=224, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789999, Length=155, Percent_Identity=27.0967741935484, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 32219; Mature: 32087

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNDAVDAEQTEKLLAPLRHELLHPIEDMQDENDRQFITALARGLELLRCFTPKHQHLG
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHCC
NQELAQMTGLPKPTITRLTHTLSRLGYIKQVPNSSKFQLSVGVLAFGYSMLSNVSIRSIA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCHHHHHH
HPYMKNLADYAGAAVAMATRDRLNMIYLDVVQGKGNMTMRRQVGTYLPIHLSSMGRACLA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHCCCCCEEHHHHHHHHHH
AMPEDEREFLLNAIRNKHKEDWIKINRDLDKAFKDYQDFGYCFSIGEWHKDVNSVAVPLI
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
HEQHGLLVFNCGGPSFIMNREKLEEDIAPRLLHMVNNIRTEIS
ECCCCEEEEECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TMNDAVDAEQTEKLLAPLRHELLHPIEDMQDENDRQFITALARGLELLRCFTPKHQHLG
CCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHCC
NQELAQMTGLPKPTITRLTHTLSRLGYIKQVPNSSKFQLSVGVLAFGYSMLSNVSIRSIA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCHHHHHH
HPYMKNLADYAGAAVAMATRDRLNMIYLDVVQGKGNMTMRRQVGTYLPIHLSSMGRACLA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHCCCCCEEHHHHHHHHHH
AMPEDEREFLLNAIRNKHKEDWIKINRDLDKAFKDYQDFGYCFSIGEWHKDVNSVAVPLI
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
HEQHGLLVFNCGGPSFIMNREKLEEDIAPRLLHMVNNIRTEIS
ECCCCEEEEECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]