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The map label for this gene is yxlA [H]

Identifier: 213156888

GI number: 213156888

Start: 1640930

End: 1642336

Strand: Direct

Name: yxlA [H]

Synonym: AB57_1559

Alternate gene names: 213156888

Gene position: 1640930-1642336 (Clockwise)

Preceding gene: 213156887

Following gene: 213156889

Centisome position: 40.51

GC content: 41.08

Gene sequence:

>1407_bases
ATGAGCCAAAACGAAAATAGCAATAATGCTTTCGCTATCGAAAGTCATTCCATTGATTATGTTGCTCCCTCTGAACGTAA
TGGGAAAGTTCGCGATCTATTCACATTATGGTTTTGTACCAATATTGCACCGCTCGCCGTGATTACGGGTGCAATGTCAA
TTTTAACCTTTAACCTCAATATTGTAAGTGCATTGCTTGCGATCTGCTGCGGACATTTTTTTGGTGCAGCGATTCTGGCC
TTAACCTCTGCACAAGGCCCACAGGTCGGCATTCCTCAAATGATTCAGAGCCGCGCACAGTTCGGGCGTTATGGGGCATT
GCTGGTTGTACTGTTTACCACCCTCATTTATTTAGGTTTTTTCATCTCTAACATTATTTTGTCAGGCAAAACCCTTCATA
CCGTTGTTCCTGCTATTCCTGTGCCGACTGCGACTGTGATTGGTGCGATTGCAGCAACCACAATTGGCGTGATCGGTTAC
CACTTTATTCATAAGTTCAATAAAATTGGAACTTGGTTTATGGGTGGTTCGTTGCTGATCGGCCTCATGATTATGGTGCC
GCATATTAATGCAGATGTACTCGCTAAAGGCTCTTTCAATATGAAAGGCTGGTTTGCCATGTTCGGCTTATGTGCGGTAT
GGCAAATTAGTTTTTCACCTTATACCTCAGACTATTCACGATATTTACCGAAGTCGATTGGTATTTATAAGCCATTTATC
TTTACCTATTTAGGCGCATCGTTAGGAACCATTTTTGCGATGGCATTTGGGACGATTGCGGTCAGTATTGGCTCAACCAC
AGATGCTATGGAAGCGGTAAAGTCAGGCACTGGGTTGTTCGGTTATGTTCTTATGATTTTGTTCTTATGCAATATCATTG
GTCACAATGCCATGAACCTATACGGTGCGGTTCTTTCTTGTATTACTTCTATTCAGACTTTTGCAGGGCAGTGGATGCCA
AGCCGAAATATCCGAGTCGTGTTATCAATCATTGTGTTAGTTCTAGCGACTTTAACGGCGCTTTGGGCATCAAGTAACTT
TATTAGTTTCTTCTTGAATGTGATTTTTGCTCTGTTATTTATTTTGGTGCCATGGGTGTCTATTAATTTACTAGATTTCT
ATGTGGTAAATAAAAAGTCTTATGACATTCAATCCATCTTTGCACGTGATGGTGGTATTTACGGCAAATTTAATGCAAAA
GCGCTTACGGCTTATTTCATTGGGATTGCGGTACAAATTCCGTTCTTAAAAAATGCGTTTTTCACAGGTGCATTGGCTGA
TGTAATTCCGGATGCGGATATTTCATGGGTCATTGGTTTGGTGGTGAGTCTGGTGGTGTATTACGTCTTTAATCTAGGAA
AGATTAAATGTTCTGCACCTGCATTAAACGCAAAATTACCTCAATAA

Upstream 100 bases:

>100_bases
AAGGAAATAAAAAGATGAAGCCGAGTCATATTGAAATGACTTTGGCTGGGCAGATTTTTTGATGTTGAGGAAATGAATTC
CTCAAAGAGAGATTAAGGAT

Downstream 100 bases:

>100_bases
GCATTGTAGTGAAAGGAATCCCACAATGAAAAAAAGCTATTTACAAGTGGCTCTAAGCACAGCATTGATGGCTGTAATCT
ATCCGAGTTACGCAGGTATA

Product: permease, cytosine/purines, uracil, thiamine, allantoin permease family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSQNENSNNAFAIESHSIDYVAPSERNGKVRDLFTLWFCTNIAPLAVITGAMSILTFNLNIVSALLAICCGHFFGAAILA
LTSAQGPQVGIPQMIQSRAQFGRYGALLVVLFTTLIYLGFFISNIILSGKTLHTVVPAIPVPTATVIGAIAATTIGVIGY
HFIHKFNKIGTWFMGGSLLIGLMIMVPHINADVLAKGSFNMKGWFAMFGLCAVWQISFSPYTSDYSRYLPKSIGIYKPFI
FTYLGASLGTIFAMAFGTIAVSIGSTTDAMEAVKSGTGLFGYVLMILFLCNIIGHNAMNLYGAVLSCITSIQTFAGQWMP
SRNIRVVLSIIVLVLATLTALWASSNFISFFLNVIFALLFILVPWVSINLLDFYVVNKKSYDIQSIFARDGGIYGKFNAK
ALTAYFIGIAVQIPFLKNAFFTGALADVIPDADISWVIGLVVSLVVYYVFNLGKIKCSAPALNAKLPQ

Sequences:

>Translated_468_residues
MSQNENSNNAFAIESHSIDYVAPSERNGKVRDLFTLWFCTNIAPLAVITGAMSILTFNLNIVSALLAICCGHFFGAAILA
LTSAQGPQVGIPQMIQSRAQFGRYGALLVVLFTTLIYLGFFISNIILSGKTLHTVVPAIPVPTATVIGAIAATTIGVIGY
HFIHKFNKIGTWFMGGSLLIGLMIMVPHINADVLAKGSFNMKGWFAMFGLCAVWQISFSPYTSDYSRYLPKSIGIYKPFI
FTYLGASLGTIFAMAFGTIAVSIGSTTDAMEAVKSGTGLFGYVLMILFLCNIIGHNAMNLYGAVLSCITSIQTFAGQWMP
SRNIRVVLSIIVLVLATLTALWASSNFISFFLNVIFALLFILVPWVSINLLDFYVVNKKSYDIQSIFARDGGIYGKFNAK
ALTAYFIGIAVQIPFLKNAFFTGALADVIPDADISWVIGLVVSLVVYYVFNLGKIKCSAPALNAKLPQ
>Mature_467_residues
SQNENSNNAFAIESHSIDYVAPSERNGKVRDLFTLWFCTNIAPLAVITGAMSILTFNLNIVSALLAICCGHFFGAAILAL
TSAQGPQVGIPQMIQSRAQFGRYGALLVVLFTTLIYLGFFISNIILSGKTLHTVVPAIPVPTATVIGAIAATTIGVIGYH
FIHKFNKIGTWFMGGSLLIGLMIMVPHINADVLAKGSFNMKGWFAMFGLCAVWQISFSPYTSDYSRYLPKSIGIYKPFIF
TYLGASLGTIFAMAFGTIAVSIGSTTDAMEAVKSGTGLFGYVLMILFLCNIIGHNAMNLYGAVLSCITSIQTFAGQWMPS
RNIRVVLSIIVLVLATLTALWASSNFISFFLNVIFALLFILVPWVSINLLDFYVVNKKSYDIQSIFARDGGIYGKFNAKA
LTAYFIGIAVQIPFLKNAFFTGALADVIPDADISWVIGLVVSLVVYYVFNLGKIKCSAPALNAKLPQ

Specific function: Transport Of Allantoin (By Similarity). [C]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320902, Length=470, Percent_Identity=23.4042553191489, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320903, Length=267, Percent_Identity=26.2172284644195, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320897, Length=409, Percent_Identity=22.7383863080685, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 50722; Mature: 50590

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNENSNNAFAIESHSIDYVAPSERNGKVRDLFTLWFCTNIAPLAVITGAMSILTFNLN
CCCCCCCCCEEEEECCCCCEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IVSALLAICCGHFFGAAILALTSAQGPQVGIPQMIQSRAQFGRYGALLVVLFTTLIYLGF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FISNIILSGKTLHTVVPAIPVPTATVIGAIAATTIGVIGYHFIHKFNKIGTWFMGGSLLI
HHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMIMVPHINADVLAKGSFNMKGWFAMFGLCAVWQISFSPYTSDYSRYLPKSIGIYKPFI
HHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHCHHHCCHHHHHH
FTYLGASLGTIFAMAFGTIAVSIGSTTDAMEAVKSGTGLFGYVLMILFLCNIIGHNAMNL
HHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
YGAVLSCITSIQTFAGQWMPSRNIRVVLSIIVLVLATLTALWASSNFISFFLNVIFALLF
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ILVPWVSINLLDFYVVNKKSYDIQSIFARDGGIYGKFNAKALTAYFIGIAVQIPFLKNAF
HHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCEEECCCHHHHHHHHHHHHEECCHHHHHH
FTGALADVIPDADISWVIGLVVSLVVYYVFNLGKIKCSAPALNAKLPQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
SQNENSNNAFAIESHSIDYVAPSERNGKVRDLFTLWFCTNIAPLAVITGAMSILTFNLN
CCCCCCCCEEEEECCCCCEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IVSALLAICCGHFFGAAILALTSAQGPQVGIPQMIQSRAQFGRYGALLVVLFTTLIYLGF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FISNIILSGKTLHTVVPAIPVPTATVIGAIAATTIGVIGYHFIHKFNKIGTWFMGGSLLI
HHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMIMVPHINADVLAKGSFNMKGWFAMFGLCAVWQISFSPYTSDYSRYLPKSIGIYKPFI
HHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHCHHHCCHHHHHH
FTYLGASLGTIFAMAFGTIAVSIGSTTDAMEAVKSGTGLFGYVLMILFLCNIIGHNAMNL
HHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
YGAVLSCITSIQTFAGQWMPSRNIRVVLSIIVLVLATLTALWASSNFISFFLNVIFALLF
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ILVPWVSINLLDFYVVNKKSYDIQSIFARDGGIYGKFNAKALTAYFIGIAVQIPFLKNAF
HHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCEEECCCHHHHHHHHHHHHEECCHHHHHH
FTGALADVIPDADISWVIGLVVSLVVYYVFNLGKIKCSAPALNAKLPQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]