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The map label for this gene is hemK [C]

Identifier: 212225058

GI number: 212225058

Start: 1796355

End: 1796939

Strand: Reverse

Name: hemK [C]

Synonym: TON_1906

Alternate gene names: 212225058

Gene position: 1796939-1796355 (Counterclockwise)

Preceding gene: 212225061

Following gene: 212225057

Centisome position: 97.26

GC content: 49.91

Gene sequence:

>585_bases
ATGATGATATATTACAAGGGACTAAAGCTCAAACTTCATCCGCAAGTCTACGAGCCAGCGGAGGATACGTTTCTCTTAGC
CGAGAACTTGGCGGTTAAACATGGCGACGTTGCCCTCGATATGGGCACCGGAACGGGCATAATAGCACTTCTGATGGCGA
GAAAGGCAGAGTACGTCCTCGGCGTTGACGTAAATCCCCTCGCCATTAAGCTGGCAAGGGAAAATGCGAGGCTCAACGGC
ATTGAAAACGTTGAGTTCATCCAGAGCAACCTCTTCGAGGGGGTTAATGGGGAGTTTGACGTCATCACCTTCAACGCGCC
GTATCTGCCCGGCGAACCCGAGGAGCCTATAGACCTAGCACTGGTGGGGGGAGAAACCGGAAGGGAAGTCCTCGACAGGT
TCATAGATGAAGTTGCCGATTATCTAAAGCCCGGTGGAATCGTTCAAATAGTTCAGAGCTCCATAACAGGAATAAAAGAG
ACTCTCGAGAGGCTGAAAGAAGTGGGTCTAAAGGGAGAAATAGCCGCTAAGAATCATGTCTTCTTTGAGGACATAGTCCT
GATAAACGCCCTGCTTGAGGATTAA

Upstream 100 bases:

>100_bases
AGAATATTTTCAAAATGTTCGAAAGATATTCGAAAAATATCCCAAAAAGCCAAAAAGACACAGGGTTAAACACAAAAAGG
TTCTGAAGATATCTACTTTC

Downstream 100 bases:

>100_bases
GCCAAATGGTGACGTTTAACTTCAAACAGGAACTTAACCTTCGGCTTGTTCTCGACCTCTGGTTCTTCCGTAGGAAAGAT
CTCGAACTCCTCCTTTTTGA

Product: N5-glutamine methyltransferase

Products: NA

Alternate protein names: M.MjaHemkP [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MMIYYKGLKLKLHPQVYEPAEDTFLLAENLAVKHGDVALDMGTGTGIIALLMARKAEYVLGVDVNPLAIKLARENARLNG
IENVEFIQSNLFEGVNGEFDVITFNAPYLPGEPEEPIDLALVGGETGREVLDRFIDEVADYLKPGGIVQIVQSSITGIKE
TLERLKEVGLKGEIAAKNHVFFEDIVLINALLED

Sequences:

>Translated_194_residues
MMIYYKGLKLKLHPQVYEPAEDTFLLAENLAVKHGDVALDMGTGTGIIALLMARKAEYVLGVDVNPLAIKLARENARLNG
IENVEFIQSNLFEGVNGEFDVITFNAPYLPGEPEEPIDLALVGGETGREVLDRFIDEVADYLKPGGIVQIVQSSITGIKE
TLERLKEVGLKGEIAAKNHVFFEDIVLINALLED
>Mature_194_residues
MMIYYKGLKLKLHPQVYEPAEDTFLLAENLAVKHGDVALDMGTGTGIIALLMARKAEYVLGVDVNPLAIKLARENARLNG
IENVEFIQSNLFEGVNGEFDVITFNAPYLPGEPEEPIDLALVGGETGREVLDRFIDEVADYLKPGGIVQIVQSSITGIKE
TLERLKEVGLKGEIAAKNHVFFEDIVLINALLED

Specific function: Putative protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Homo sapiens, GI87159829, Length=177, Percent_Identity=33.8983050847458, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI87159831, Length=169, Percent_Identity=31.9526627218935, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787463, Length=159, Percent_Identity=31.4465408805031, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193204212, Length=162, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320344, Length=183, Percent_Identity=31.1475409836066, Blast_Score=88, Evalue=8e-19,
Organism=Drosophila melanogaster, GI78706836, Length=164, Percent_Identity=30.4878048780488, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004557
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 21324; Mature: 21324

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIYYKGLKLKLHPQVYEPAEDTFLLAENLAVKHGDVALDMGTGTGIIALLMARKAEYVL
CEEEEECCEEEECCCCCCCCCCEEEEECCCEEECCCEEEECCCCHHHHHHHHHHCCCEEE
GVDVNPLAIKLARENARLNGIENVEFIQSNLFEGVNGEFDVITFNAPYLPGEPEEPIDLA
ECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEE
LVGGETGREVLDRFIDEVADYLKPGGIVQIVQSSITGIKETLERLKEVGLKGEIAAKNHV
EECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCH
FFEDIVLINALLED
HHHHHHHHHHHHCC
>Mature Secondary Structure
MMIYYKGLKLKLHPQVYEPAEDTFLLAENLAVKHGDVALDMGTGTGIIALLMARKAEYVL
CEEEEECCEEEECCCCCCCCCCEEEEECCCEEECCCEEEECCCCHHHHHHHHHHCCCEEE
GVDVNPLAIKLARENARLNGIENVEFIQSNLFEGVNGEFDVITFNAPYLPGEPEEPIDLA
ECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEE
LVGGETGREVLDRFIDEVADYLKPGGIVQIVQSSITGIKETLERLKEVGLKGEIAAKNHV
EECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCH
FFEDIVLINALLED
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]