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The map label for this gene is 212225057

Identifier: 212225057

GI number: 212225057

Start: 1795105

End: 1796091

Strand: Reverse

Name: 212225057

Synonym: TON_1905

Alternate gene names: NA

Gene position: 1796091-1795105 (Counterclockwise)

Preceding gene: 212225058

Following gene: 212225056

Centisome position: 97.21

GC content: 53.5

Gene sequence:

>987_bases
ATGGCGATAACGTTCAAGTCCAATCCAAACATGCCGGGCGAGATTGCGAGACTGTTTAAAAAGCAGCATTACGCTCTCGT
GGGCAGACACAGCTCAGTCAAGCTCTGCCACTGGCTCAAAGAGAGCATAAAGCACGACAGGTTCTGTTACAAGCAGAAGT
TCTACGGAATACACTCCCACCGCTGTCTGCAGATGACGCCGGTTACTGCATGGTGCACCCACAACTGCATCTTCTGCTGG
CGTCCCATGGAGGGCTTCCTTGGAACCGAGCTTCCTGGACCCTGGGACGACCCGGCTTTCATAGTCGAGGAGAGCATAAA
GGCCCAGCGCAAGCTCCTCGTCGGCTACAAGGGCATGCCTGGAATAAACATGAAGAAGTTCGAGGAGGCCTGGAATCCGA
AGCACGCCGCCATAAGTCTCTCCGGTGAGCCGATGCTCTATCCATACATGGGCGATCTAGTTGAGGAGTTCCACAAGCGC
GGATTCACCACCTTCATAGTCACAAACGGAACCGCTCCGGAGAGACTCGAAGAGATGATTAAGGAGGACAAGCTTCCGAC
CCAGCTCTACGTCTCGCTCACCGCTCCAGACATAGAGACCTACAACCGCGTCAATGTCCCAATGATTCCCGACGGCTGGG
AGAAAATAACAAGAACCCTCGAGCTCATGAACGGTCTGCCAACGAGGACGGTGATAAGACTCACGCTCGTCAAGGACGAG
AACATGCACAATCCAGAGGGCTACGCAAAGCTCATAATGAAGGCCAAACCAATGTTCGTCGAGGCCAAAGCCTACATGTT
CGTCGGCTTCTCGAGGAACCGACTCACGATAAACAACATGCCGCGCCATGAAGAAATCAAGACCTTCGCAGAGGAGCTTG
TCAAGCACCTGCCCGGCTACCACATCGAGGACGAGTACGAGCCGAGCCGTGTCGTTCTTATAATGCGCGATGATGTGGAC
AAAACAGAACGCTTCATAAAGCACTGA

Upstream 100 bases:

>100_bases
TTCTCCGATTGACGAATAGTTTTTCGACGATAAAATATGGGACAGCTTTGTTCCCAACATCTTTTTAAAAGGGTGTCTGA
AGTGGAGTTAGGTGAGACTA

Downstream 100 bases:

>100_bases
GCTTTCTCTCCCCTTTTTATGGAAAAAGTTTATTTATTCTGGCCGCTTAGAATGAACCTAGGGGTGTAAGATGATGAAGA
AAGTTCTGGCTTTAATGATG

Product: tRNA-modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MAITFKSNPNMPGEIARLFKKQHYALVGRHSSVKLCHWLKESIKHDRFCYKQKFYGIHSHRCLQMTPVTAWCTHNCIFCW
RPMEGFLGTELPGPWDDPAFIVEESIKAQRKLLVGYKGMPGINMKKFEEAWNPKHAAISLSGEPMLYPYMGDLVEEFHKR
GFTTFIVTNGTAPERLEEMIKEDKLPTQLYVSLTAPDIETYNRVNVPMIPDGWEKITRTLELMNGLPTRTVIRLTLVKDE
NMHNPEGYAKLIMKAKPMFVEAKAYMFVGFSRNRLTINNMPRHEEIKTFAEELVKHLPGYHIEDEYEPSRVVLIMRDDVD
KTERFIKH

Sequences:

>Translated_328_residues
MAITFKSNPNMPGEIARLFKKQHYALVGRHSSVKLCHWLKESIKHDRFCYKQKFYGIHSHRCLQMTPVTAWCTHNCIFCW
RPMEGFLGTELPGPWDDPAFIVEESIKAQRKLLVGYKGMPGINMKKFEEAWNPKHAAISLSGEPMLYPYMGDLVEEFHKR
GFTTFIVTNGTAPERLEEMIKEDKLPTQLYVSLTAPDIETYNRVNVPMIPDGWEKITRTLELMNGLPTRTVIRLTLVKDE
NMHNPEGYAKLIMKAKPMFVEAKAYMFVGFSRNRLTINNMPRHEEIKTFAEELVKHLPGYHIEDEYEPSRVVLIMRDDVD
KTERFIKH
>Mature_327_residues
AITFKSNPNMPGEIARLFKKQHYALVGRHSSVKLCHWLKESIKHDRFCYKQKFYGIHSHRCLQMTPVTAWCTHNCIFCWR
PMEGFLGTELPGPWDDPAFIVEESIKAQRKLLVGYKGMPGINMKKFEEAWNPKHAAISLSGEPMLYPYMGDLVEEFHKRG
FTTFIVTNGTAPERLEEMIKEDKLPTQLYVSLTAPDIETYNRVNVPMIPDGWEKITRTLELMNGLPTRTVIRLTLVKDEN
MHNPEGYAKLIMKAKPMFVEAKAYMFVGFSRNRLTINNMPRHEEIKTFAEELVKHLPGYHIEDEYEPSRVVLIMRDDVDK
TERFIKH

Specific function: Unknown

COG id: COG0731

COG function: function code C; Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0026 family [H]

Homologues:

Organism=Homo sapiens, GI50726981, Length=295, Percent_Identity=37.9661016949153, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI224282123, Length=257, Percent_Identity=35.0194552529183, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI224282125, Length=257, Percent_Identity=35.0194552529183, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6325049, Length=303, Percent_Identity=35.973597359736, Blast_Score=210, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197
- InterPro:   IPR013917 [H]

Pfam domain/function: PF04055 Radical_SAM; PF08608 Wyosine_form [H]

EC number: NA

Molecular weight: Translated: 38237; Mature: 38106

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITFKSNPNMPGEIARLFKKQHYALVGRHSSVKLCHWLKESIKHDRFCYKQKFYGIHSH
CEEEECCCCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RCLQMTPVTAWCTHNCIFCWRPMEGFLGTELPGPWDDPAFIVEESIKAQRKLLVGYKGMP
CEEEECCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCC
GINMKKFEEAWNPKHAAISLSGEPMLYPYMGDLVEEFHKRGFTTFIVTNGTAPERLEEMI
CCCHHHHHHHCCCCCEEEEECCCCEECHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
KEDKLPTQLYVSLTAPDIETYNRVNVPMIPDGWEKITRTLELMNGLPTRTVIRLTLVKDE
HHCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECC
NMHNPEGYAKLIMKAKPMFVEAKAYMFVGFSRNRLTINNMPRHEEIKTFAEELVKHLPGY
CCCCCHHHHHHHHHCCCEEEEEEEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHCCCC
HIEDEYEPSRVVLIMRDDVDKTERFIKH
CCCCCCCCCEEEEEEECCCHHHHHHHCC
>Mature Secondary Structure 
AITFKSNPNMPGEIARLFKKQHYALVGRHSSVKLCHWLKESIKHDRFCYKQKFYGIHSH
EEEECCCCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RCLQMTPVTAWCTHNCIFCWRPMEGFLGTELPGPWDDPAFIVEESIKAQRKLLVGYKGMP
CEEEECCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCC
GINMKKFEEAWNPKHAAISLSGEPMLYPYMGDLVEEFHKRGFTTFIVTNGTAPERLEEMI
CCCHHHHHHHCCCCCEEEEECCCCEECHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
KEDKLPTQLYVSLTAPDIETYNRVNVPMIPDGWEKITRTLELMNGLPTRTVIRLTLVKDE
HHCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECC
NMHNPEGYAKLIMKAKPMFVEAKAYMFVGFSRNRLTINNMPRHEEIKTFAEELVKHLPGY
CCCCCHHHHHHHHHCCCEEEEEEEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHCCCC
HIEDEYEPSRVVLIMRDDVDKTERFIKH
CCCCCCCCCEEEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]