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The map label for this gene is wbbL [H]

Identifier: 212225013

GI number: 212225013

Start: 1741623

End: 1742618

Strand: Reverse

Name: wbbL [H]

Synonym: TON_1861

Alternate gene names: 212225013

Gene position: 1742618-1741623 (Counterclockwise)

Preceding gene: 212225014

Following gene: 212225012

Centisome position: 94.32

GC content: 45.98

Gene sequence:

>996_bases
ATGAGTCTTTCAAATAAGGCAAGTGTAATTATAGTCACGTACAACCACAAAAAATACATGGGGGACTGTTTAACTTCCGT
TCTAGCCAATGATCCGTTAGAGGTCATTGTTGTCGATAACGGCTCCACGGATAAAACTCCCGAGTTCATTGAAGAGAACT
TTCCAGAGGTTAAGGTCATAAGGAGTCCAAGGAATTTAGGCTATGGAGGAGGGAACAATTTAGGAGTTAGACATGCAAAA
GGAGAATACGTGGTGATCCTCAATCCAGACACGAAGGTTGGGGAGAACTGGCTCGAGGAACTCGTTAGGCCACTGTCTAA
AAGTAGGCGTTTGATAACGACCCCAAAGATACTCCTTTATGATGGCTCAGCTATAAATACAGTTGGAAACATTGTTCACT
TTACCGGACTCACGTTCACCAGGGGCTACTTGGAGCCTCCTGAGAAGTACAACAAGCCAGAATACCTCAGCGGCATTTCT
GGGGCATGCTTTGCCATGAGGAGAGACGAATATCTTGAACTGGGAGGGTTTGACGAGAACTTTTTAGCGTACAACGAGGA
CGGGGAGTTCTCATGGAGGGCCCATGCCAAGGGTTTCAAAATCCTGTACGTGCCGACATCGGTGGTTTATCACGACTACA
CCCTTAAAGTACCGCCGAAGAAAATATACCATCTGGAGAAAGGGAGGTACATTATTTTGAGGAAGTACTTAACGGCACGC
CAGAGGCTTGCAATCCTGCCCTCTCTGATTATGAGTGAGATACTGACCTGGGGGTACGCGGTACTGAACGGGCCATCGGG
CATAAAATTCAAGCTTAAGGGCCTTTTTGAGGGTTTAAAAGCTGAAGTGGATAAGATTGAAGCAGGTGAAGGGATACTCC
AAGGACTGGATAGCCAAATCCCCGATGACCAGCTATCCTACACTCCAATTGATAGGATTATTAAAAGAATCGCCAACAGG
ATTTACGAATGGAACTACAGGGTGATAGCAGGATGA

Upstream 100 bases:

>100_bases
CCCCGCCATCGGCTCGGGGATCTTCGCGATAATCGGGATCCAGCTGTTCGTTGCTGGATTGACGCTGAACGTGCTGGCAA
AGATGGTGAGGGAGTGAGAT

Downstream 100 bases:

>100_bases
AGATAGCTCTTGTGTGCTCTCATGGAGGGCATCTGACGGAGATGCTCTACTTAATGGAGGCATTTAGGGGGCATGAGGTG
TTTTTTGTAACTTATGACAA

Product: glycosyltransferase

Products: NA

Alternate protein names: Rhamnosyltransferase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSLSNKASVIIVTYNHKKYMGDCLTSVLANDPLEVIVVDNGSTDKTPEFIEENFPEVKVIRSPRNLGYGGGNNLGVRHAK
GEYVVILNPDTKVGENWLEELVRPLSKSRRLITTPKILLYDGSAINTVGNIVHFTGLTFTRGYLEPPEKYNKPEYLSGIS
GACFAMRRDEYLELGGFDENFLAYNEDGEFSWRAHAKGFKILYVPTSVVYHDYTLKVPPKKIYHLEKGRYIILRKYLTAR
QRLAILPSLIMSEILTWGYAVLNGPSGIKFKLKGLFEGLKAEVDKIEAGEGILQGLDSQIPDDQLSYTPIDRIIKRIANR
IYEWNYRVIAG

Sequences:

>Translated_331_residues
MSLSNKASVIIVTYNHKKYMGDCLTSVLANDPLEVIVVDNGSTDKTPEFIEENFPEVKVIRSPRNLGYGGGNNLGVRHAK
GEYVVILNPDTKVGENWLEELVRPLSKSRRLITTPKILLYDGSAINTVGNIVHFTGLTFTRGYLEPPEKYNKPEYLSGIS
GACFAMRRDEYLELGGFDENFLAYNEDGEFSWRAHAKGFKILYVPTSVVYHDYTLKVPPKKIYHLEKGRYIILRKYLTAR
QRLAILPSLIMSEILTWGYAVLNGPSGIKFKLKGLFEGLKAEVDKIEAGEGILQGLDSQIPDDQLSYTPIDRIIKRIANR
IYEWNYRVIAG
>Mature_330_residues
SLSNKASVIIVTYNHKKYMGDCLTSVLANDPLEVIVVDNGSTDKTPEFIEENFPEVKVIRSPRNLGYGGGNNLGVRHAKG
EYVVILNPDTKVGENWLEELVRPLSKSRRLITTPKILLYDGSAINTVGNIVHFTGLTFTRGYLEPPEKYNKPEYLSGISG
ACFAMRRDEYLELGGFDENFLAYNEDGEFSWRAHAKGFKILYVPTSVVYHDYTLKVPPKKIYHLEKGRYIILRKYLTARQ
RLAILPSLIMSEILTWGYAVLNGPSGIKFKLKGLFEGLKAEVDKIEAGEGILQGLDSQIPDDQLSYTPIDRIIKRIANRI
YEWNYRVIAG

Specific function: Involved in the biosynthesis of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of the rhamnosyl moiety from dTDP-rhamnosyl (dTDP-Rha) onto the undecaprenyl-pyrophosphoryl

COG id: COG1216

COG function: function code R; Predicted glycosyltransferases

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI157502212, Length=237, Percent_Identity=27.8481012658228, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI281485547, Length=225, Percent_Identity=26.2222222222222, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71996085, Length=203, Percent_Identity=27.0935960591133, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71996090, Length=203, Percent_Identity=27.0935960591133, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561826, Length=236, Percent_Identity=26.6949152542373, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584318, Length=235, Percent_Identity=26.3829787234043, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: NA

Molecular weight: Translated: 37417; Mature: 37285

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSNKASVIIVTYNHKKYMGDCLTSVLANDPLEVIVVDNGSTDKTPEFIEENFPEVKVI
CCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCCCEEEE
RSPRNLGYGGGNNLGVRHAKGEYVVILNPDTKVGENWLEELVRPLSKSRRLITTPKILLY
ECCCCCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEECCEEEEE
DGSAINTVGNIVHFTGLTFTRGYLEPPEKYNKPEYLSGISGACFAMRRDEYLELGGFDEN
CCCHHHHHHHHHEECCCEEECCCCCCHHHCCCCHHHCCCCHHHEEECCCCEEECCCCCCC
FLAYNEDGEFSWRAHAKGFKILYVPTSVVYHDYTLKVPPKKIYHLEKGRYIILRKYLTAR
CEEECCCCCEEEEECCCCEEEEEEECEEEEEEEEEECCHHHHEEECCCCEEEEEHHHHHH
QRLAILPSLIMSEILTWGYAVLNGPSGIKFKLKGLFEGLKAEVDKIEAGEGILQGLDSQI
HHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
PDDQLSYTPIDRIIKRIANRIYEWNYRVIAG
CCCCCCCCCHHHHHHHHHHHHEECCEEEECC
>Mature Secondary Structure 
SLSNKASVIIVTYNHKKYMGDCLTSVLANDPLEVIVVDNGSTDKTPEFIEENFPEVKVI
CCCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCCCEEEE
RSPRNLGYGGGNNLGVRHAKGEYVVILNPDTKVGENWLEELVRPLSKSRRLITTPKILLY
ECCCCCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEECCEEEEE
DGSAINTVGNIVHFTGLTFTRGYLEPPEKYNKPEYLSGISGACFAMRRDEYLELGGFDEN
CCCHHHHHHHHHEECCCEEECCCCCCHHHCCCCHHHCCCCHHHEEECCCCEEECCCCCCC
FLAYNEDGEFSWRAHAKGFKILYVPTSVVYHDYTLKVPPKKIYHLEKGRYIILRKYLTAR
CEEECCCCCEEEEECCCCEEEEEEECEEEEEEEEEECCHHHHEEECCCCEEEEEHHHHHH
QRLAILPSLIMSEILTWGYAVLNGPSGIKFKLKGLFEGLKAEVDKIEAGEGILQGLDSQI
HHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
PDDQLSYTPIDRIIKRIANRIYEWNYRVIAG
CCCCCCCCCHHHHHHHHHHHHEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]