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The map label for this gene is ileS [H]

Identifier: 212224954

GI number: 212224954

Start: 1673201

End: 1676398

Strand: Reverse

Name: ileS [H]

Synonym: TON_1803

Alternate gene names: 212224954

Gene position: 1676398-1673201 (Counterclockwise)

Preceding gene: 212224955

Following gene: 212224950

Centisome position: 90.73

GC content: 56.07

Gene sequence:

>3198_bases
ATGATAAGGGAGCCAGAGTTTAGGGAGTATTCTCCAGGGAAGCTGGAAGAGAAAGTCGAGCGCTTTTGGAAGGAGAACAA
CGTCTATGAGAAGGTGAAGGCCAGCAGAGCAAACGGCCCGAAGTACTACTTCCTCGACGGGCCGCCCTACGTCAGCGGTG
CCATACACCTCGGAACGGCCTGGAACAAGATAATCAAGGACATGGTGATAAGGTTCAGGACCATGCAGGGCTACAACGTT
CGCAGGCAGCCGGGCTTCGACATGCACGGACTGCCGATAGAGGTCAAGGTCGAGCAGGCTCTCGGCCTGAAGACCAAGAA
GGACATAGAGACCGAGATAGGCGTTGACGAGTTCATAAGGAAGTGTAAGGAGTTCGCCCTCAACAACCTCAAGGTGATGA
CCGAGCAGTTCAAGATGCTCGGCATATGGATGGACTGGGACAACCCCTACATGACCATAAAGAACGAGTACATAGAATCG
GGCTGGTTCACGCTCAAGCGCGCCTGGGAGAAGGGCCTCCTCGAGAAGGACAAGAGGGTTCTGCACTGGTGTCCGCGCTG
TGAGACGGCTCTCGCTGAACACGAGGTTCGCGGTGAGTACAAGATAAGGAAGGACCCGAGCATATACGTCAAGTTCCCGG
TTGAGGGCAAAGACAACGAGTACCTTCTCATCTGGACAACCACGCCGTGGACTCTTCCGGCCAACCTCGCGGTTGCAGTT
CATCCCGAATACGACTACGTCAAGGTCAGGGTCGAGACCGAGAACGGCGAGGAGTACTGGATAGTGGCCAAGGCCTTGGC
TGAGAGAGTTCTCAACGAGGTCGGCGTTAAGGGCGAGATAGTCGAGGAGTTCAAGGGTGAAGACCTCGAGGGACTCCGCT
ACATGCACATACTCATGGAGGAGTACCCAACTCAGAAGGAGTTCCGCGAGAGGTACGAGTGGGCCCACCGCGTTATCCTC
GGCGAGCACGTGACGCTTGAGGACGGTACCGGACTGGTTCACACCGCACCGGGCCACGGTGAGGAAGACTTCGAAGTCGG
AAGGGAGTACGGCCTTCCGGCGTATTCACCAGTTGATGACCAGGGCAGATACGTGGAGGGCAGATGGAATGGAGTCTACG
TCAAAGACGCCGACCCCGAGATCATAGAACACCTCAAGGAGAAGGGCTACCTCGTCAAGGCCGGAACGATAGAGCACAAA
TATCCGCACTGCTGGCGCTGTAAGACGCCGCTTATATTCCGCGCCACCGACCAGTGGTTCCTCAAGGTCAGCAAGGTCAA
AGACCAGATAATCAAGGAGAACGACGAGAAGGTGACCTGGTACCCCGACTGGGTGAAGGTCAGGTACGACAACGGCGTCA
TGAACTCCGGAGATTGGGTCATAAGCAGACAGCGCTACTGGGGAATACCCCTGCCGATATGGCAGAGTGAGGACGGCGAA
ATATACGTCGTTGGAAGCTTTGAGGAGCTTGTCAAGCTTTCCGTGGCCATAGAAGTGAACGGCGAGAGGATAGACCTCCC
GGAGGACTACAGCGAGAAGCTCAGGGTCATCGAAGAGAAGCTCGGCCCGGAGGACCTCCACAGGCCCTACGTGGATGCAT
TCATCATAAAGGTCAACGGCAAGGAGATGCGCCGCGTTAAGGACGTCGTTGACGTCTGGTTTGACAGCGGAATAGCCAGC
TGGGCTTCCCTCGACTACCCGAGAAACGAGGAGCTCTTCAAGGAGCTCTGGCCGGCAGACTTCATAGTCGAGGGTGAAGA
CCAAGTAACCAAGTGGTTCTACTCCCAGCAGGCGGCCAGCGTTATAGCCTTCGACACAGTCCCCTACAGGAAGGTCGCCA
TGCACGGCTACGTCCTCGACGAAAAGGGCGACAAGATGAGCAAGAGCCTCGGCAACATCATAAGGCCGGAAGAGGTCGTC
CAGAAGGAAGGAAGGGACCCCTTCAGGTTCTACATGCTCTGGGCCACCAACCCCTGGGAAAACCTCAAGTTCAGCTGGAA
GGGCCTGGCTCAGGTCAAGAGGATGCTCAACATACTATGGAACGTCTACGTTTTGAGCGCCACCTACATGAGCCTGGATA
ACTTTGACCCGACTAGAGTCAATCCCGAGGAGCTGCCTTTCCGCGAGGAGGACAGGTGGATACTAAGCAGGGTCAACAGC
CTCATAGGAGAAGTCACGGAGGGCATAGAGACCTTCAGGCTTACCAAGGCAACGAGGGCGATATACAACTTCGTCGTCGA
GGACCTGAGCAGGTGGTACATCAGGCTGATCAGGAAGCGCATGTGGGTTGAAGGCGACGACCCGGACAAGTTAGCTGCCT
ACTACACCGTCTGGAAGGTCTTCAACGTCCTCCTGAGGCTTATGGCACCCTTCACGCCATACATAGCTGAAGAGATATAC
CAGAACCTCCTCAAGCCGTTCCTTGGCGTTGAGAGCGTCCACATGCTCGACTGGCCGAAGGCAGATGAGAAGACCATTGA
TGAAGAGCTCGAGAAGGAGATGGAAGCCGTAAGGAAGATAGTCGAGGCCGGCTCAGCGGCAAGGCAGAAGGCCAAGATAA
AGCTCCGCTACCCTGTTAGGAGAATAATCATAGAGACCGAGGACGAGACCGTAAAGAGGGCTGTCGAGAGGCTTAACAGA
CTGCTCAGGGATCAGCTCAACGCTAAGGAGGTCGTCGTTGGAAGGGTCGAGCGTGAGCTGATAATAAAGCCGAACTTCGC
GAAGGTCGGGCCGGAGTTCAAGGGCGACGCCAGACTCGTCTCCCAGTGGATAGCCGAGCACGGCAGGGAGCTCTACCAGG
CCGGCGAGATGGACGTCGAGATAGAGGGCAAGACCTTCCACCTCACAAAGGAGCACCTGACCATAGAGGAGAAGCTCCCG
GACTTCTTCGTTGCTGAGGACTTCGACGGCGGAAGGGTCTTCGTGGACAAGACCCTCACCAGGGAGCTCCTCGCTGAGGG
CCTCGCGAGGGAGTTCGTCAGGAGAATACAGGAGATGAGGAAGAGGCTCGACCTCGACGTCAACGACAGGATAGTTGTCA
CCATAGAGACCACCGACGAGAATCGCGAACTGCTCCAGGAGAACCTTGACTACATAGAGAGGGAGACGAGGGCAACTGAG
GTCATCTTCGGCGAGGCCAAGGGCTACGTGGTTGAGTGGCCCGAAGTTCAGGCGAAGATAGGGATTGAAGAGGTTTGA

Upstream 100 bases:

>100_bases
GTGTTTTATCCTTCGCTCTGCTCGTTTCGAGTAAGGCCCCTCACTGTTCTGAGCTAGTTAGTTCTAACTTTCCTTTCAAA
GACCACAGGGAGGTTTTGAA

Downstream 100 bases:

>100_bases
GCCTTCTCACTTTTCCAAAATTTCATTCTTCGTCTTCTCTTGAATTCCCCAACTGAGTGAGTATCCAAGAGTTTATCCAG
TCTTCAACTTCCTTGAGCTC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS [H]

Number of amino acids: Translated: 1065; Mature: 1065

Protein sequence:

>1065_residues
MIREPEFREYSPGKLEEKVERFWKENNVYEKVKASRANGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMVIRFRTMQGYNV
RRQPGFDMHGLPIEVKVEQALGLKTKKDIETEIGVDEFIRKCKEFALNNLKVMTEQFKMLGIWMDWDNPYMTIKNEYIES
GWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKIRKDPSIYVKFPVEGKDNEYLLIWTTTPWTLPANLAVAV
HPEYDYVKVRVETENGEEYWIVAKALAERVLNEVGVKGEIVEEFKGEDLEGLRYMHILMEEYPTQKEFRERYEWAHRVIL
GEHVTLEDGTGLVHTAPGHGEEDFEVGREYGLPAYSPVDDQGRYVEGRWNGVYVKDADPEIIEHLKEKGYLVKAGTIEHK
YPHCWRCKTPLIFRATDQWFLKVSKVKDQIIKENDEKVTWYPDWVKVRYDNGVMNSGDWVISRQRYWGIPLPIWQSEDGE
IYVVGSFEELVKLSVAIEVNGERIDLPEDYSEKLRVIEEKLGPEDLHRPYVDAFIIKVNGKEMRRVKDVVDVWFDSGIAS
WASLDYPRNEELFKELWPADFIVEGEDQVTKWFYSQQAASVIAFDTVPYRKVAMHGYVLDEKGDKMSKSLGNIIRPEEVV
QKEGRDPFRFYMLWATNPWENLKFSWKGLAQVKRMLNILWNVYVLSATYMSLDNFDPTRVNPEELPFREEDRWILSRVNS
LIGEVTEGIETFRLTKATRAIYNFVVEDLSRWYIRLIRKRMWVEGDDPDKLAAYYTVWKVFNVLLRLMAPFTPYIAEEIY
QNLLKPFLGVESVHMLDWPKADEKTIDEELEKEMEAVRKIVEAGSAARQKAKIKLRYPVRRIIIETEDETVKRAVERLNR
LLRDQLNAKEVVVGRVERELIIKPNFAKVGPEFKGDARLVSQWIAEHGRELYQAGEMDVEIEGKTFHLTKEHLTIEEKLP
DFFVAEDFDGGRVFVDKTLTRELLAEGLAREFVRRIQEMRKRLDLDVNDRIVVTIETTDENRELLQENLDYIERETRATE
VIFGEAKGYVVEWPEVQAKIGIEEV

Sequences:

>Translated_1065_residues
MIREPEFREYSPGKLEEKVERFWKENNVYEKVKASRANGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMVIRFRTMQGYNV
RRQPGFDMHGLPIEVKVEQALGLKTKKDIETEIGVDEFIRKCKEFALNNLKVMTEQFKMLGIWMDWDNPYMTIKNEYIES
GWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKIRKDPSIYVKFPVEGKDNEYLLIWTTTPWTLPANLAVAV
HPEYDYVKVRVETENGEEYWIVAKALAERVLNEVGVKGEIVEEFKGEDLEGLRYMHILMEEYPTQKEFRERYEWAHRVIL
GEHVTLEDGTGLVHTAPGHGEEDFEVGREYGLPAYSPVDDQGRYVEGRWNGVYVKDADPEIIEHLKEKGYLVKAGTIEHK
YPHCWRCKTPLIFRATDQWFLKVSKVKDQIIKENDEKVTWYPDWVKVRYDNGVMNSGDWVISRQRYWGIPLPIWQSEDGE
IYVVGSFEELVKLSVAIEVNGERIDLPEDYSEKLRVIEEKLGPEDLHRPYVDAFIIKVNGKEMRRVKDVVDVWFDSGIAS
WASLDYPRNEELFKELWPADFIVEGEDQVTKWFYSQQAASVIAFDTVPYRKVAMHGYVLDEKGDKMSKSLGNIIRPEEVV
QKEGRDPFRFYMLWATNPWENLKFSWKGLAQVKRMLNILWNVYVLSATYMSLDNFDPTRVNPEELPFREEDRWILSRVNS
LIGEVTEGIETFRLTKATRAIYNFVVEDLSRWYIRLIRKRMWVEGDDPDKLAAYYTVWKVFNVLLRLMAPFTPYIAEEIY
QNLLKPFLGVESVHMLDWPKADEKTIDEELEKEMEAVRKIVEAGSAARQKAKIKLRYPVRRIIIETEDETVKRAVERLNR
LLRDQLNAKEVVVGRVERELIIKPNFAKVGPEFKGDARLVSQWIAEHGRELYQAGEMDVEIEGKTFHLTKEHLTIEEKLP
DFFVAEDFDGGRVFVDKTLTRELLAEGLAREFVRRIQEMRKRLDLDVNDRIVVTIETTDENRELLQENLDYIERETRATE
VIFGEAKGYVVEWPEVQAKIGIEEV
>Mature_1065_residues
MIREPEFREYSPGKLEEKVERFWKENNVYEKVKASRANGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMVIRFRTMQGYNV
RRQPGFDMHGLPIEVKVEQALGLKTKKDIETEIGVDEFIRKCKEFALNNLKVMTEQFKMLGIWMDWDNPYMTIKNEYIES
GWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKIRKDPSIYVKFPVEGKDNEYLLIWTTTPWTLPANLAVAV
HPEYDYVKVRVETENGEEYWIVAKALAERVLNEVGVKGEIVEEFKGEDLEGLRYMHILMEEYPTQKEFRERYEWAHRVIL
GEHVTLEDGTGLVHTAPGHGEEDFEVGREYGLPAYSPVDDQGRYVEGRWNGVYVKDADPEIIEHLKEKGYLVKAGTIEHK
YPHCWRCKTPLIFRATDQWFLKVSKVKDQIIKENDEKVTWYPDWVKVRYDNGVMNSGDWVISRQRYWGIPLPIWQSEDGE
IYVVGSFEELVKLSVAIEVNGERIDLPEDYSEKLRVIEEKLGPEDLHRPYVDAFIIKVNGKEMRRVKDVVDVWFDSGIAS
WASLDYPRNEELFKELWPADFIVEGEDQVTKWFYSQQAASVIAFDTVPYRKVAMHGYVLDEKGDKMSKSLGNIIRPEEVV
QKEGRDPFRFYMLWATNPWENLKFSWKGLAQVKRMLNILWNVYVLSATYMSLDNFDPTRVNPEELPFREEDRWILSRVNS
LIGEVTEGIETFRLTKATRAIYNFVVEDLSRWYIRLIRKRMWVEGDDPDKLAAYYTVWKVFNVLLRLMAPFTPYIAEEIY
QNLLKPFLGVESVHMLDWPKADEKTIDEELEKEMEAVRKIVEAGSAARQKAKIKLRYPVRRIIIETEDETVKRAVERLNR
LLRDQLNAKEVVVGRVERELIIKPNFAKVGPEFKGDARLVSQWIAEHGRELYQAGEMDVEIEGKTFHLTKEHLTIEEKLP
DFFVAEDFDGGRVFVDKTLTRELLAEGLAREFVRRIQEMRKRLDLDVNDRIVVTIETTDENRELLQENLDYIERETRATE
VIFGEAKGYVVEWPEVQAKIGIEEV

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1086, Percent_Identity=32.4125230202578, Blast_Score=534, Evalue=1e-151,
Organism=Homo sapiens, GI94721241, Length=1086, Percent_Identity=32.4125230202578, Blast_Score=534, Evalue=1e-151,
Organism=Homo sapiens, GI46852147, Length=799, Percent_Identity=31.5394242803504, Blast_Score=359, Evalue=8e-99,
Organism=Homo sapiens, GI268370293, Length=929, Percent_Identity=23.0355220667384, Blast_Score=200, Evalue=7e-51,
Organism=Homo sapiens, GI268370297, Length=929, Percent_Identity=23.0355220667384, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI268370295, Length=888, Percent_Identity=23.3108108108108, Blast_Score=195, Evalue=2e-49,
Organism=Homo sapiens, GI5454158, Length=886, Percent_Identity=22.9119638826185, Blast_Score=184, Evalue=4e-46,
Organism=Homo sapiens, GI7661872, Length=181, Percent_Identity=28.1767955801105, Blast_Score=70, Evalue=9e-12,
Organism=Escherichia coli, GI2367096, Length=806, Percent_Identity=33.2506203473945, Blast_Score=420, Evalue=1e-118,
Organism=Escherichia coli, GI1790708, Length=945, Percent_Identity=22.962962962963, Blast_Score=212, Evalue=8e-56,
Organism=Escherichia coli, GI1786861, Length=943, Percent_Identity=23.541887592789, Blast_Score=138, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17541896, Length=1047, Percent_Identity=32.7602674307545, Blast_Score=508, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI71980946, Length=816, Percent_Identity=27.4509803921569, Blast_Score=288, Evalue=8e-78,
Organism=Caenorhabditis elegans, GI17510661, Length=925, Percent_Identity=23.2432432432432, Blast_Score=203, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI72001587, Length=902, Percent_Identity=22.6164079822616, Blast_Score=180, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1088, Percent_Identity=32.0772058823529, Blast_Score=523, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6325217, Length=869, Percent_Identity=30.1495972382048, Blast_Score=318, Evalue=4e-87,
Organism=Saccharomyces cerevisiae, GI6321531, Length=857, Percent_Identity=24.0373395565928, Blast_Score=188, Evalue=4e-48,
Organism=Drosophila melanogaster, GI28574730, Length=1062, Percent_Identity=31.1676082862524, Blast_Score=504, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24668547, Length=1062, Percent_Identity=31.1676082862524, Blast_Score=504, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24668543, Length=1062, Percent_Identity=31.1676082862524, Blast_Score=504, Evalue=1e-143,
Organism=Drosophila melanogaster, GI281366294, Length=811, Percent_Identity=31.9358816276202, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI17864482, Length=987, Percent_Identity=23.9108409321175, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24653289, Length=987, Percent_Identity=23.9108409321175, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21355675, Length=909, Percent_Identity=22.4422442244224, Blast_Score=187, Evalue=3e-47,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 125105; Mature: 125105

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIREPEFREYSPGKLEEKVERFWKENNVYEKVKASRANGPKYYFLDGPPYVSGAIHLGTA
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCCCEEEECHH
WNKIIKDMVIRFRTMQGYNVRRQPGFDMHGLPIEVKVEQALGLKTKKDIETEIGVDEFIR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHCCCCCCCCHHHCCHHHHHH
KCKEFALNNLKVMTEQFKMLGIWMDWDNPYMTIKNEYIESGWFTLKRAWEKGLLEKDKRV
HHHHHHHHHHHHHHHHEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LHWCPRCETALAEHEVRGEYKIRKDPSIYVKFPVEGKDNEYLLIWTTTPWTLPANLAVAV
HHHCCCHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEE
HPEYDYVKVRVETENGEEYWIVAKALAERVLNEVGVKGEIVEEFKGEDLEGLRYMHILME
CCCCCEEEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHH
EYPTQKEFRERYEWAHRVILGEHVTLEDGTGLVHTAPGHGEEDFEVGREYGLPAYSPVDD
HCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCC
QGRYVEGRWNGVYVKDADPEIIEHLKEKGYLVKAGTIEHKYPHCWRCKTPLIFRATDQWF
CCCEEEEEECEEEEECCCHHHHHHHHHCCEEEEECCCCCCCCCCEECCCCEEEEECHHHH
LKVSKVKDQIIKENDEKVTWYPDWVKVRYDNGVMNSGDWVISRQRYWGIPLPIWQSEDGE
HHHHHHHHHHHCCCCCEEEEECCEEEEEECCCCCCCCCEEEECCCCCCCCCCCEECCCCC
IYVVGSFEELVKLSVAIEVNGERIDLPEDYSEKLRVIEEKLGPEDLHRPYVDAFIIKVNG
EEEEECHHHHEEEEEEEEECCCEECCCCCHHHHHHHHHHHCCHHHHCCCCEEEEEEEECC
KEMRRVKDVVDVWFDSGIASWASLDYPRNEELFKELWPADFIVEGEDQVTKWFYSQQAAS
HHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHCC
VIAFDTVPYRKVAMHGYVLDEKGDKMSKSLGNIIRPEEVVQKEGRDPFRFYMLWATNPWE
EEEECCCCCHHHHHCCEEECCCCCHHHHHHCCCCCCHHHHHHCCCCCEEEEEEEECCCCC
NLKFSWKGLAQVKRMLNILWNVYVLSATYMSLDNFDPTRVNPEELPFREEDRWILSRVNS
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHHHHHHHH
LIGEVTEGIETFRLTKATRAIYNFVVEDLSRWYIRLIRKRMWVEGDDPDKLAAYYTVWKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FNVLLRLMAPFTPYIAEEIYQNLLKPFLGVESVHMLDWPKADEKTIDEELEKEMEAVRKI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
VEAGSAARQKAKIKLRYPVRRIIIETEDETVKRAVERLNRLLRDQLNAKEVVVGRVEREL
HHCCHHHHHCCEEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHEECCEEE
IIKPNFAKVGPEFKGDARLVSQWIAEHGRELYQAGEMDVEIEGKTFHLTKEHLTIEEKLP
EECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEHHHEEHHHHCC
DFFVAEDFDGGRVFVDKTLTRELLAEGLAREFVRRIQEMRKRLDLDVNDRIVVTIETTDE
CEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
NRELLQENLDYIERETRATEVIFGEAKGYVVEWPEVQAKIGIEEV
HHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECCCHHCCCCCCCC
>Mature Secondary Structure
MIREPEFREYSPGKLEEKVERFWKENNVYEKVKASRANGPKYYFLDGPPYVSGAIHLGTA
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCCCEEEECHH
WNKIIKDMVIRFRTMQGYNVRRQPGFDMHGLPIEVKVEQALGLKTKKDIETEIGVDEFIR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHCCCCCCCCHHHCCHHHHHH
KCKEFALNNLKVMTEQFKMLGIWMDWDNPYMTIKNEYIESGWFTLKRAWEKGLLEKDKRV
HHHHHHHHHHHHHHHHEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LHWCPRCETALAEHEVRGEYKIRKDPSIYVKFPVEGKDNEYLLIWTTTPWTLPANLAVAV
HHHCCCHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEE
HPEYDYVKVRVETENGEEYWIVAKALAERVLNEVGVKGEIVEEFKGEDLEGLRYMHILME
CCCCCEEEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHH
EYPTQKEFRERYEWAHRVILGEHVTLEDGTGLVHTAPGHGEEDFEVGREYGLPAYSPVDD
HCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCC
QGRYVEGRWNGVYVKDADPEIIEHLKEKGYLVKAGTIEHKYPHCWRCKTPLIFRATDQWF
CCCEEEEEECEEEEECCCHHHHHHHHHCCEEEEECCCCCCCCCCEECCCCEEEEECHHHH
LKVSKVKDQIIKENDEKVTWYPDWVKVRYDNGVMNSGDWVISRQRYWGIPLPIWQSEDGE
HHHHHHHHHHHCCCCCEEEEECCEEEEEECCCCCCCCCEEEECCCCCCCCCCCEECCCCC
IYVVGSFEELVKLSVAIEVNGERIDLPEDYSEKLRVIEEKLGPEDLHRPYVDAFIIKVNG
EEEEECHHHHEEEEEEEEECCCEECCCCCHHHHHHHHHHHCCHHHHCCCCEEEEEEEECC
KEMRRVKDVVDVWFDSGIASWASLDYPRNEELFKELWPADFIVEGEDQVTKWFYSQQAAS
HHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHCC
VIAFDTVPYRKVAMHGYVLDEKGDKMSKSLGNIIRPEEVVQKEGRDPFRFYMLWATNPWE
EEEECCCCCHHHHHCCEEECCCCCHHHHHHCCCCCCHHHHHHCCCCCEEEEEEEECCCCC
NLKFSWKGLAQVKRMLNILWNVYVLSATYMSLDNFDPTRVNPEELPFREEDRWILSRVNS
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHHHHHHHH
LIGEVTEGIETFRLTKATRAIYNFVVEDLSRWYIRLIRKRMWVEGDDPDKLAAYYTVWKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FNVLLRLMAPFTPYIAEEIYQNLLKPFLGVESVHMLDWPKADEKTIDEELEKEMEAVRKI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
VEAGSAARQKAKIKLRYPVRRIIIETEDETVKRAVERLNRLLRDQLNAKEVVVGRVEREL
HHCCHHHHHCCEEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHEECCEEE
IIKPNFAKVGPEFKGDARLVSQWIAEHGRELYQAGEMDVEIEGKTFHLTKEHLTIEEKLP
EECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEHHHEEHHHHCC
DFFVAEDFDGGRVFVDKTLTRELLAEGLAREFVRRIQEMRKRLDLDVNDRIVVTIETTDE
CEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
NRELLQENLDYIERETRATEVIFGEAKGYVVEWPEVQAKIGIEEV
HHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA