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The map label for this gene is 212224823

Identifier: 212224823

GI number: 212224823

Start: 1536582

End: 1537655

Strand: Reverse

Name: 212224823

Synonym: TON_1672

Alternate gene names: NA

Gene position: 1537655-1536582 (Counterclockwise)

Preceding gene: 212224829

Following gene: 212224822

Centisome position: 83.22

GC content: 52.05

Gene sequence:

>1074_bases
ATGAAGCAGAGAAAAGCTTGGCGGGTTGTGAGAGAGGTAATTGACGAGGCCGATATCATCGTCGAGGTAGTTGACGCGCG
AGACCCTATAGGAACGAGGAACAGAAAACTGGAGAGGCTCGTTAAGGAGGAGGGAAAGCCGCTCCTTATAGTCATGAACA
AGGCTGACCTCGTGCCCAAGGAGTGGGCCGAGGAGTATAAGAGAAAGAGCGAGATTCCGGTCGTTTTTATCTCCGCCCGC
GAGAGGAAGGGAACTGGAATTTTAAGGAGGGAAATCAAAAAGCTCGCAAAGGGCCTGCTGGACTATCAGGATAAAGTTAA
GGTGGCCCTCATAGGCTATCCCAACGTCGGCAAGAGCACGATAATCAACACGCTGAAGGGCAAGAAGGCCGTAGGAACAG
CCCCTATTCCAGGCTACACAAAGGGGAAGCAGCTCATAAGGCTGAGCAAAAAGATATGGCTTCTCGACAGTCCTGGAGTT
GTTCCCATAGATGACTTCGACGAGCTAGTCATCAAAGGAGGTTTTCCTGCAGACAAGATAGAGGAGCCAGTTAAGCCGGC
ACTGAAGCTCATCGGCAGAATCCTGGAGACGAGAAAGGAGGCGCTAACGGAGAAGTTTGGCATTGAAGACTTTTCCAGCG
AGGAAGATATCCTCAGGGAGATAGGAAAGCGAAAGGGCATAATCAGGAAGGGCGGTGAGGTTGACCTTGAGGAAACGGCT
CGCTGGCTTCTCCGCGAGTGGCAGACCGGAAGGTTCACCCTCTTTGGAAAGGAGGAAGAGAAAGGCCAAGAGTTCGTCTG
GGACTTCGAGGATGTTCTTGATGGCATCGAGAAGGATTTGCTCCTCGACCCAAGGAGGATACTCTGGAAATACGGCGAAG
AGCTGAGGGAAAAGCTTGACAACACGAAGCGGGTTGGAATAAGGGAAATTGAGGGGTTCACCGTTGGCATCGCGACGGGC
TTCAAGAAGTGCGACGGCGGAATAAAGCTCCTCGAAAAGCTCACCGGAAAGCACGCCCTTGCGAGTGAGTGCTTTGGGAA
GAAGTGGAAGGGTGTCGTTGTGATAATGGAGTGA

Upstream 100 bases:

>100_bases
GGGCTTGGTAGGGGAGAGAAAGCCTACGTGCAGTGCCTTGATCCTGGACCGCCCTACACAGACGGAGGGACGGTAATCTT
TGAGATAACGGTGGTGCGAG

Downstream 100 bases:

>100_bases
TGAAGGATGAGACTGCTACTCACGACTTCTCAGGGAATCGAAGATTTAGCAAAGGCCGAGGTAGAGAGCCTTCTCAGCCA
GCTTGGAGTTTCGTTTCTGG

Product: GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKQRKAWRVVREVIDEADIIVEVVDARDPIGTRNRKLERLVKEEGKPLLIVMNKADLVPKEWAEEYKRKSEIPVVFISAR
ERKGTGILRREIKKLAKGLLDYQDKVKVALIGYPNVGKSTIINTLKGKKAVGTAPIPGYTKGKQLIRLSKKIWLLDSPGV
VPIDDFDELVIKGGFPADKIEEPVKPALKLIGRILETRKEALTEKFGIEDFSSEEDILREIGKRKGIIRKGGEVDLEETA
RWLLREWQTGRFTLFGKEEEKGQEFVWDFEDVLDGIEKDLLLDPRRILWKYGEELREKLDNTKRVGIREIEGFTVGIATG
FKKCDGGIKLLEKLTGKHALASECFGKKWKGVVVIME

Sequences:

>Translated_357_residues
MKQRKAWRVVREVIDEADIIVEVVDARDPIGTRNRKLERLVKEEGKPLLIVMNKADLVPKEWAEEYKRKSEIPVVFISAR
ERKGTGILRREIKKLAKGLLDYQDKVKVALIGYPNVGKSTIINTLKGKKAVGTAPIPGYTKGKQLIRLSKKIWLLDSPGV
VPIDDFDELVIKGGFPADKIEEPVKPALKLIGRILETRKEALTEKFGIEDFSSEEDILREIGKRKGIIRKGGEVDLEETA
RWLLREWQTGRFTLFGKEEEKGQEFVWDFEDVLDGIEKDLLLDPRRILWKYGEELREKLDNTKRVGIREIEGFTVGIATG
FKKCDGGIKLLEKLTGKHALASECFGKKWKGVVVIME
>Mature_357_residues
MKQRKAWRVVREVIDEADIIVEVVDARDPIGTRNRKLERLVKEEGKPLLIVMNKADLVPKEWAEEYKRKSEIPVVFISAR
ERKGTGILRREIKKLAKGLLDYQDKVKVALIGYPNVGKSTIINTLKGKKAVGTAPIPGYTKGKQLIRLSKKIWLLDSPGV
VPIDDFDELVIKGGFPADKIEEPVKPALKLIGRILETRKEALTEKFGIEDFSSEEDILREIGKRKGIIRKGGEVDLEETA
RWLLREWQTGRFTLFGKEEEKGQEFVWDFEDVLDGIEKDLLLDPRRILWKYGEELREKLDNTKRVGIREIEGFTVGIATG
FKKCDGGIKLLEKLTGKHALASECFGKKWKGVVVIME

Specific function: Unknown

COG id: COG1161

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI7019419, Length=265, Percent_Identity=37.3584905660377, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI296317324, Length=284, Percent_Identity=30.9859154929577, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI9506611, Length=284, Percent_Identity=30.9859154929577, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI45643129, Length=274, Percent_Identity=29.5620437956204, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI45643127, Length=274, Percent_Identity=29.5620437956204, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI45593130, Length=274, Percent_Identity=29.5620437956204, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI223029424, Length=162, Percent_Identity=29.6296296296296, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534827, Length=280, Percent_Identity=31.7857142857143, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI32563985, Length=276, Percent_Identity=34.7826086956522, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71990926, Length=276, Percent_Identity=34.7826086956522, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI32563983, Length=276, Percent_Identity=34.7826086956522, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI25143545, Length=280, Percent_Identity=30.3571428571429, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI115535155, Length=280, Percent_Identity=30.3571428571429, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6324381, Length=263, Percent_Identity=31.1787072243346, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6320842, Length=294, Percent_Identity=28.9115646258503, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321339, Length=313, Percent_Identity=28.1150159744409, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI19922460, Length=264, Percent_Identity=35.2272727272727, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI28572990, Length=282, Percent_Identity=29.7872340425532, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI18543229, Length=176, Percent_Identity=30.6818181818182, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI85815858, Length=296, Percent_Identity=24.6621621621622, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023179
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR000795 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 40687; Mature: 40687

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRKAWRVVREVIDEADIIVEVVDARDPIGTRNRKLERLVKEEGKPLLIVMNKADLVPK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHH
EWAEEYKRKSEIPVVFISARERKGTGILRREIKKLAKGLLDYQDKVKVALIGYPNVGKST
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
IINTLKGKKAVGTAPIPGYTKGKQLIRLSKKIWLLDSPGVVPIDDFDELVIKGGFPADKI
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCCCHHHHHEECCCCHHHH
EEPVKPALKLIGRILETRKEALTEKFGIEDFSSEEDILREIGKRKGIIRKGGEVDLEETA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHH
RWLLREWQTGRFTLFGKEEEKGQEFVWDFEDVLDGIEKDLLLDPRRILWKYGEELREKLD
HHHHHHCCCCCEEEECCCHHCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
NTKRVGIREIEGFTVGIATGFKKCDGGIKLLEKLTGKHALASECFGKKWKGVVVIME
CHHCCCCEECCCEEEEHHHCHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MKQRKAWRVVREVIDEADIIVEVVDARDPIGTRNRKLERLVKEEGKPLLIVMNKADLVPK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHH
EWAEEYKRKSEIPVVFISARERKGTGILRREIKKLAKGLLDYQDKVKVALIGYPNVGKST
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
IINTLKGKKAVGTAPIPGYTKGKQLIRLSKKIWLLDSPGVVPIDDFDELVIKGGFPADKI
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCCCHHHHHEECCCCHHHH
EEPVKPALKLIGRILETRKEALTEKFGIEDFSSEEDILREIGKRKGIIRKGGEVDLEETA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHH
RWLLREWQTGRFTLFGKEEEKGQEFVWDFEDVLDGIEKDLLLDPRRILWKYGEELREKLD
HHHHHHCCCCCEEEECCCHHCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
NTKRVGIREIEGFTVGIATGFKKCDGGIKLLEKLTGKHALASECFGKKWKGVVVIME
CHHCCCCEECCCEEEEHHHCHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]